Think about this scenario, suppose there’s a person who has never drank alcohol before. You start him on a diet of beer and wines. Over time he develops a tolerance for alcohol(maybe because of more alcohol dehydrogenase?).
Is this a good thing? Perhaps…but at the same time just because you can drink more doesn’t mean you won’t feel the same effects of increased alcohol consumption(organ damage, beer belly etc). You also put yourself at the risk of damaging the liver and actually impairing function.
that certainly is true, but the fact that the recptor will be up-regulated will occur when blocking the AChR for longer periods. The site of the inhibition will determine the outcome of ‘the experiment’.
