Autism spectrum disorder (ASD) refers to a group of complex neurodevelopment disorders that cause significant social, communication and behavioral challenges. Now, a new study reports on a potential drug target that increases social interaction in ASD.
It has been reported that a gene termed Protocadherin 10 (PCDH10) is implicated in ASD. In this study, the researchers created mice that lacked one copy of PCDH10 (Pcdh10+/–), and found that male Pcdh10+/– mice had decreased social approach behavior, as well as anomalies in the structure and function of amygdala circuitry. When the researchers treated these mice with a drug termed d-cycloserine, their social approach deficits were reversed. You will get to know more about the study from http://about.cusabio.com/c-19791.html