- August 28, 2012 at 10:11 pm #16781
How does the lining of the small intestine absorb the B12/intrinsic factor complex into the bloodstream? Does the B12 separate from the intrinsic factor or are the two absorbed as a unit?
- August 29, 2012 at 6:35 pm #112204
Basically, how does intrinsic factor work?
- September 8, 2012 at 3:57 pm #112256david23Participant
This is a pretty straightforward thing, you dont trust wikipedia? intrinsic factor has to bind to b12 for it to be endocytosed.
If you rephrase your question ask what is B12 deficiency like then I can help you there because that sounds more like the questions you are wondering.
- September 10, 2012 at 5:31 pm #112297
Once the B12/intrinsic factor complex gets endocytosed (by what kind of cells?) and into the blood stream, where does it go next? When does the complex get broken up?
- September 11, 2012 at 12:45 am #112304david23Participant
Oh since we are in the small intestine I have guess maybe enterocytes. The complexes are broken once it gets taken. From blood it goes to a lot of places, oh like your CNS first example.
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