Bcl-2 family proteins

Viewing 0 reply threads
  • Author
    Posts
    • #11907
      barny876
      Participant

      Bcl-2 family proteins, which include pro- and antiapoptotic members, positively or negatively regulate MOM permeabilization, i.e. a barrier to apoptosis induction. Over-expression of pro-survival members is associated with tumor progression and may be responsible for drug resistance, while pro-apoptotic members may promote sustained cell death during both acute injuries and chronic degenerative disorders. Detailed understanding of the precise biochemical mechanisms by which Bcl-2 family members control mitochondrial apoptosis is therefore of considerable therapeutic interest. (More information about the lab “POROS” on Labslink.com) 😆

Viewing 0 reply threads
  • You must be logged in to reply to this topic.