change in alle frequency with selelction - Biology Forum

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CXCR4 15 years, 8 months ago

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- February 25, 2009 at 7:08 pm #10963
  nena77
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  I have a problem with the articel of Lebowitz in Theor Appl Genet, 1987
  Trait based analysis for the detection of linkages between marker loci and quantitative trait loci in crosses between inbred lines.
  in a F2 population with genotypes AA Aa aa at the QTL ( only one QTL is supposed to exist) the difference in allele frequency as a result of one step selection , carried out at both tail of the phenotypic normal distribution is
  =iD/4
  where i is the standardized selection differential
  D= is the proportional effect of the QTL
  why is it everythinf divided by 4?
  for a BC population the same forumal would be divided by 8-…..why?
  thanks
  Elena
- April 18, 2009 at 4:33 pm #90202
  CXCR4
  Participant
  Do you think it can become natural selection
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