DNA-binding molecules

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    • #11109
      Lurrena
      Participant

      Explain how DNA-binding proteins can make sequence specific contacts to a double stranded
      DNA molecule without breaking the hydrogen bonds that hold the bases
      together.

      Anyone got the answer to this?

    • #89852
      MrMistery
      Participant

      when we were discussing DNA-binding proteins a teaching assistant in my molecular bio course gave us the following joke.
      "I make naked DNA bend over and insert my beta sheet into its minor groove. Who am I?" though that’s not the regular way this takes place, it was very entertaining.

    • #89858
      plasmodesmata11
      Participant

      heard of leucine zippers and zinc fingers? google that.

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