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    • #14420
      ILoveISO
      Participant

      for example if I was told to draw Val-Ser-Gly would I draw the three structures and connect them by peptide bonds? If so now the next step what would I do if I was told to draw it in PH = 5.7 and PH = 7.7? How would I show the differences?

    • #103315
      JackBean
      Participant

      it’s pH 🙄

      you need to find out the pKa of ionizable groups and if the pH is above the pKa, it will be deprotonized, if it’s bellow, the group will be protonized.

    • #103321
      ILoveISO
      Participant

      So basically if it is protonized or not you would represent it in the drawing by either adding and H to the structure or removing it?

    • #103322
      JackBean
      Participant

      yes, but of course only those groups, which can be de/protonized

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