last updated by JackBean 15 years ago
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    • #12587
      plasmodesmata11
      Participant

      Awhile ago I posted something about cell constance. It was bothering me the other day, and after a bit of perusing, I found out it was more properly termed eutely. With this title, hopefully more people will get it…
      Does anyone know exactly how and why this happens? I read something and it mentioned the organism using quorum sensing, a new topic to me. The site says "These cells communicate with each other chemically in a process called quorum sensing to ensure that the total number of cells in the colony remains constant over time." Then I looked up quorum sensing and it said it was used for groups of organisms, not within an organism. Does it secrete the signal molecules in the EM or something? Or is it just wrong (The site looked like garbage)? And if so, what is the mechanism and how could it be imposed on other cells?
      And also, what is the viability of inducing or using eutely as an anticancer strategy/ treatment?
      Thanks

    • #96593
      JackBean
      Participant

      here
      http://www.wisegeek.com/what-is-eutely.htm
      they write, that it’s achieved by limited number of cell divisions.
      In the case of chemical signal I would guess something like growth factors and stuff, but I think, that would not guarantee the exact number 😉

    • #96610
      plasmodesmata11
      Participant

      alright… how does a cell come with limited divisions? does it have to do with things that control the cell cycle? do they get it stuck in an arrested phase using CDKs?

    • #96614
      JackBean
      Participant

      IMHO CDKs or anything related to cell cycle itself won’t guarantee exact number of divisions, again. I would guess something like telomeres…?

    • #96772
      plasmodesmata11
      Participant

      are you referring to the hayflick limit?

    • #96778
      JackBean
      Participant

      sorry? 😳

    • #96804
      plasmodesmata11
      Participant

      http://en.wikipedia.org/wiki/Hayflick_limit
      then the cells undergo apoptosis…

    • #96805
      JackBean
      Participant

      yes, probably something like that

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