December 5, 2012 at 3:56 pm #17118
I have a question to ask.Can gene targeting be done in human being . I mean a fully grown person.And can anyone say what would be a suitable vector for using.
December 5, 2012 at 4:51 pm #113195JackBeanParticipant
what about gene therapy?
December 6, 2012 at 11:40 pm #113201
Here’s a very recent publication with a few well-known vector examples. Certainly there are other possibilities. This essay also points out some potential pitfalls.
http://www.nature.com/nm/journal/v18/n1 … -1718.html
I think RNA targeting is an easier way to treat many genetic conditions.
December 9, 2012 at 4:03 pm #113206
hello thank you for your response
Does gene targeting has been successful in human being in much accuracy?
can you please explain in short about cis and trans.Actually i am trying to know more about gene targeting so if you dont mind can you explain.Can retro virus can also be used as vector?
December 11, 2012 at 3:54 pm #113225
Very little work has been done in humans because of the strict regulations governing human clinical trials.
December 16, 2012 at 7:24 am #113243
oh ok thank you sir.
December 18, 2012 at 2:03 pm #113260
sir is it possible to remove a specific gene if its locus in the dna is known by gene targeting in humans ?
December 18, 2012 at 4:47 pm #113261
It might be possible (in theory, though it would not be allowed) to remove a gene from a gamete or a single-celled zygote. However, in an adult human you would have to remove the gene from every cell, and there is no technology available to alter the DNA in so many cells at once.
December 25, 2012 at 3:16 pm #113298
sir but is it possible to do so in a couple of cell say a hand full of those?
December 26, 2012 at 4:51 pm #113303
Yes. Delivery efficiency to cells in adult tissue will not be 100%. There are likely to be regulatory barriers (legal restrictions). But, in principle it is possible.
December 28, 2012 at 12:47 pm #113307
oh ok sir thank you actually.If you dont mind can you say the ways gene targeting is done.This may be silly question but i am just doing my 12th grade so please tolerate with me sir.
thank you for your time.
January 2, 2013 at 6:21 pm #113321
January 12, 2013 at 2:05 pm #113369
thank you sir.
April 23, 2013 at 2:30 pm #113741
I need help.I have finished my 12th grade and i wish to become Genetic Engineer.Which course should i take in mu Under Graduation if i wanted to do Masters in Genetic.I want to do Genetic Engineering in U.S.A and i am from INDIA.Please someone help me pls pls pls.My time is running out so pls pls pls.
Thanks for your time..:)
April 25, 2013 at 6:11 pm #113743
These come to mind.
organic chemistry (chemistry major’s year sequence)
biochemistry (chemistry major’s year sequence)
recombinant DNA techniques
instrumental chemical analysis
programming (for instance, C++ or a similar language)
Likely you won’t find courses with exactly these names in the course catalog of your school, but try to get some exposure in these topics.
June 10, 2013 at 8:58 am #113939
hello can anyone give the name of the gene involved in the production of telomerase and does in a normal cell production of telomerase is stopped???.
thank you for your time.
June 13, 2013 at 2:34 pm #113952webtech8899Participant
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July 27, 2013 at 5:06 pm #114123
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