Gluconeogenesis

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    • #16616
      billyfisher100
      Participant

      Hello all.

      What is the origin of HCO3- where it enters at the first step of gluconeogenesis? Is it from carbonic anhydrase?

      Thanks 🙂

    • #111622
      JackBean
      Participant

      There is equilibrium between CO2 and (HCO3)-

    • #111623
      JackBean
      Participant

      And yes, the equilibrium is maintained by carbonic anhydrase, but even without it there would be some (HCO3)-, but it could be replenished quickly.

    • #111635
      billyfisher100
      Participant

      Thanks very much! Is there any compartmentalisation of carbonic anhydrase, or can it be present anywhere?

    • #111637
      JackBean
      Participant

      http://www.brenda-enzymes.info/php/resu … no=4.2.1.1
      look for localization (seems to be present basically everywhere)

    • #111750
      billyfisher100
      Participant

      Thanks 🙂

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