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      Jessiyoo
      Participant

      Hi,

      I know that depolarization of a cell –> activates VGCC –> Ca2+ increases –> opens TRPM5 channels to let more Ca2+ in. But my questions are:
      1. What is the mechanism behind the activation of VGCC?
      2. How can TRPM5 channels open (how can they sense that they have to open)?

      //Jessie

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