How to search the short sequence among the nuclear acid bank

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    • #15568
      seahow
      Participant

      Hi,I want search some consensus in the genome using blast program on human genome database. But when I enter the sequence which is about 10 base long , the BLAST show me “No significant similarity found” I have enlarge the expect threshold to 10000. And the sequence I entered is really in the human genome.

      Should I change the program but blast? Or others, thanks!

    • #107112
      JackBean
      Participant

      try the NCBI BLAST, it should automatically set for short sequences. There are also some algoritms for searching consensus sequences, whit AAs far from each other.

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