- November 21, 2005 at 9:26 pm #2607burningredphoenixParticipant
it’s in the body, but where does body get it frm, it can’t get it from salt
- November 21, 2005 at 9:29 pm #33200
Why not from salt? salt is NaCl.
- November 21, 2005 at 9:38 pm #33201mithParticipant
I got the impression that HCl is created from proton pumps. I was doing my Russian history homework yesterday and I read about Rasputin and how he survived cyanide(incredible story, he survived like 3 assasination attempts). Anyway he had a disease that inhibits production of HCl.
- November 22, 2005 at 3:14 am #33222burningredphoenixParticipant
It can’t come from salt, The ion concentration would increase, however, the voltage difference would just rebond Cl to Na .
- November 22, 2005 at 4:41 pm #33245
So what is NaCl used for in your body?
- November 22, 2005 at 6:27 pm #33251
NaCl is a soruce of minerals, nothing more. Na and Cl are some of the most important minerals in the body. But the concentration is a fixed point(homeostazy) so eating more NaCl won’t help you have more minerals in the body.
Now, Dave is right. HCl is not present in the cells of the stomach(i think the reason is obvious) so cells excrete K+ and Cl- separatly into the lumen by active transporters, and then they combine to form HCl, which is so important for the digestion process
- November 23, 2005 at 12:29 pm #33308victorParticipantquote MrMistery:
K+ and Cl- will form KCl….where’s the H+ needed to form HCl ?
- November 23, 2005 at 6:39 pm #33337
I wrote K+ instead of H+. You want the real process? Fine!
Downloading from IBO training memory:
Co2 enters the parietal cell according to concentration gradient. There, the enzyme carbonic anhidrase is present. It catalises the reaction:
CO2 + H2O–> HCO3- + H+
H+ is excreted into the lumen through a pump identical to the one plants use to create H+ gradients
Now, Cl- enters the cell through an antiport with HCO3-, so the cell solves 2 problems: gets rid of HCO3- and gets the Cl- inside the cell. Then Cl- is excreted into the lumen through an ion channel according to the Gibbs-Donnan equilibrium. This channel is only present in the part of the cell facing the lumen.
Any questions? 😉
- November 24, 2005 at 12:10 pm #33417MjhavokParticipantquote mithrilhack:
That is quite interesting
- November 24, 2005 at 4:53 pm #33437quote MrMistery:
- November 24, 2005 at 6:32 pm #33441
LOL… Don’t be afraid to ask Ozge… 🙂
By the way, a cool thing to know is that specific inhbitors for the H+ pump are used in treating stomach ulcer. I don’t really know what they are called, but i don’t think anyone really cares so…
- November 29, 2005 at 11:40 pm #33849Terry K.Participant
Doesn’t nexium have those inhibitors, or is my memory for TV fading away as I speak?
- November 30, 2005 at 6:49 pm #33912
No idea… What’s nexium?
- December 20, 2005 at 3:16 am #35226MjhavokParticipant
Esomeprazole magnesium trihydrate. nexium is just the trademarked name I think. It used in stomach ulcer diseases as a proton pump inhibitor.
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