hydrochloric acid

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    • #2607
      burningredphoenix
      Participant

      it’s in the body, but where does body get it frm, it can’t get it from salt

    • #33200
      Poison
      Participant

      Why not from salt? salt is NaCl.

    • #33201
      mith
      Participant

      I got the impression that HCl is created from proton pumps. I was doing my Russian history homework yesterday and I read about Rasputin and how he survived cyanide(incredible story, he survived like 3 assasination attempts). Anyway he had a disease that inhibits production of HCl.

      http://en.wikipedia.org/wiki/Achlorhydria

    • #33222
      burningredphoenix
      Participant

      It can’t come from salt, The ion concentration would increase, however, the voltage difference would just rebond Cl to Na .

    • #33245
      Poison
      Participant

      So what is NaCl used for in your body?

    • #33251
      MrMistery
      Participant

      NaCl is a soruce of minerals, nothing more. Na and Cl are some of the most important minerals in the body. But the concentration is a fixed point(homeostazy) so eating more NaCl won’t help you have more minerals in the body.
      Now, Dave is right. HCl is not present in the cells of the stomach(i think the reason is obvious) so cells excrete K+ and Cl- separatly into the lumen by active transporters, and then they combine to form HCl, which is so important for the digestion process

    • #33308
      victor
      Participant
      quote MrMistery:

      so cells excrete K+ and Cl- separatly into the lumen by active transporters, and then they combine to form HCl, which is so important for the digestion process

      K+ and Cl- will form KCl….where’s the H+ needed to form HCl ?

    • #33337
      MrMistery
      Participant

      I wrote K+ instead of H+. You want the real process? Fine!
      Downloading from IBO training memory:
      Co2 enters the parietal cell according to concentration gradient. There, the enzyme carbonic anhidrase is present. It catalises the reaction:
      CO2 + H2O–> HCO3- + H+
      H+ is excreted into the lumen through a pump identical to the one plants use to create H+ gradients
      Now, Cl- enters the cell through an antiport with HCO3-, so the cell solves 2 problems: gets rid of HCO3- and gets the Cl- inside the cell. Then Cl- is excreted into the lumen through an ion channel according to the Gibbs-Donnan equilibrium. This channel is only present in the part of the cell facing the lumen.

      Any questions? 😉

    • #33417
      Mjhavok
      Participant
      quote mithrilhack:

      I got the impression that HCl is created from proton pumps. I was doing my Russian history homework yesterday and I read about Rasputin and how he survived cyanide(incredible story, he survived like 3 assasination attempts). Anyway he had a disease that inhibits production of HCl.

      http://en.wikipedia.org/wiki/Achlorhydria

      That is quite interesting

    • #33437
      Poison
      Participant
      quote MrMistery:

      Any questions? 😉

      😯 Nope

    • #33441
      MrMistery
      Participant

      LOL… Don’t be afraid to ask Ozge… 🙂
      By the way, a cool thing to know is that specific inhbitors for the H+ pump are used in treating stomach ulcer. I don’t really know what they are called, but i don’t think anyone really cares so…

    • #33849
      Terry K.
      Participant

      Doesn’t nexium have those inhibitors, or is my memory for TV fading away as I speak?

    • #33912
      MrMistery
      Participant

      No idea… What’s nexium?

    • #35226
      Mjhavok
      Participant

      Esomeprazole magnesium trihydrate. nexium is just the trademarked name I think. It used in stomach ulcer diseases as a proton pump inhibitor.

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