Is thiamin (thiamine) amine or not?

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    • #17820
      boron
      Participant

      I’ve read (exactly here) that the name thiamine was changed to thiamin "after it was found it’s not an amine." Thiamin does have a NH2 group, so why wouldn’t it be amine? ChemSpider

    • #115538
      BasicBiology
      Participant

      From what it looks like to me, thiamine might not be an amine because the amino group is connected to an aromatic ring. I know phenylamines are amine groups connected to benzene rings. In thiamine, the amine group is connected to a pyrimidine ring. So I’m not sure but this may be why thiamine is not considered an amine…

    • #115635
      boron
      Participant

      Examples of amines in the Merriam-Webster dictionary include dopamine and histamine, in both of which, amino group is attached to a carbohydrate chain, not to the ring.

      Yes, in thiamin, NH2 is attached directly to the ring.

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