Biology Forum Genetics Is this right

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    • #8519
      jjfptl
      Participant

      Hi,
      I have a problem in genetics and I was wondering if it is correct, I am pretty sure this is right, just want to make sure:

      Mutants 1, 2, 3, and 4 were analyzed and each was found to accumulate one compound (A – D), as indicated in the following table.
      Mutant Accumulation
      1 A
      2 B
      3 D
      4 D

      The pathway for phenylalanine biosynthesis is given below. Place mutants 1,2,3 and 4 in the pathway to show the reaction each gene catalyzes.

      X -> R -> B -> A -> D -> phenylalanine

      ANSWER : X -> R (2) -> B (1) -> A (3,4)-> D -> phenylalanine

      and is this because: if mutant 1 accumulates A then enzyme B-A-lase is mutant 1, R-B-lase is mutant 2, A-D-lase is mutant 3 and 4. and they all have enzymes to synthesis of phenylalanine.

      Just want to make sure i am understanding this. Thanks all

    • #77510
      mith
      Participant

      If mutant 1 has inactive form for A->D enzyme, does that mean A accumulates since it cannot be further processed?

    • #77511
      jjfptl
      Participant

      Did I confuse something here?

      Now I think I may be lost.

    • #77516
      mith
      Participant

      You said

      if mutant 1 accumulates A then enzyme B-A-lase is mutant

      However, if B->A is mutant, doesn’t that mean that it accumulates B, since it cannot further process it into A?

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