Biology Forum › Cell Biology › myofibroblasts
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- January 5, 2010 at 1:22 pm #12557
kk
ParticipantIs there a clear difference between fibroblasts and myofibroblasts?
As far as I am concerned, there are certain markers to identify myofibroblasts. I am sure some cells are permanently myofibroblasts (e.g. in the mammary gland?), but can a regular fibroblast trans-differentiate to myofibroblast upon certain signals (e.g. mechanical stress)? Does a regular fibroblast have nice stress fibers with all components or only myofibroblasts have alpha-smooth muscle actin as a component of their stress fibers?
Thank you in advance for any input. 😉
- January 12, 2010 at 9:27 am #96615
kk
ParticipantYes, an extensive answer can be found under the link below:
http://www.jbiomech.com/article/S0021-9290(09)00511-9/abstract
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