NADH and FADH2

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    • #1244
      victor
      Participant

      NADH and FADH2 give electron and H+ to start ETS. My question is how many ATP will be formed from ETS for each NADH and FADH2??

    • #25254
      Jelanen
      Participant

      Use the search function!!!! This kind of stuff has been hashed, rehashed and recycled hashed.

      http://www.biology-online.org/biology-forum/viewtopic.php?t=582&highlight=fadh+nadh

      -Jelanen

    • #26229
      Dr.Stein
      Participant

      1 NADH will generates 3 ATPs
      1 FADH2 will generates 2 ATPs

      Jelanen: You can merge similar topics or close one of them to reduce tons of topic in this board. Just a little suggestion, because I also a moderator of a forum of something else 😉

    • #26423
      victor
      Participant

      I read the biochem book and have it checked again and again…it said that aerobic respiration generates 36 ATP per glucose molecule…and if we count again:
      Glycolysis = 2 ATP and 2 NADH
      Oxydative decarbocilation = 2 NADH
      Krebs = 6 NADH, 2 FADH2, 2 ATP (or can be GTP based on body necessity)
      ETS = changes NADH and FADH2 into ATP

      We see that there’re 10 NADH, 2 FADH2 and 4 ATP.
      Then the result will be 38 ATPs…but the book said that there’re only 36 ATPs per glucose molecule…how can?? (if we make ATP in Krebs are involved because the book wrote it ATP not GTP)

    • #26448
      Poison
      Participant

      We either say 36 or 38 ATP. Depending on the pathway used. These are the 2 pathways: Malate Dehydrogenase, Glycerol-Phosphate Dehydrogenase.
      This is the point:

      quote :

      Glycolysis = 2 ATP and 2 NADH

      Let me explain it to you roughly. That 2 NADH (formed during glycolysis) give their H to the either NAD or FAD which is present in the mitochondria. (means that those NADH are not used directly.) If they give their H to FAD, present in the mitochondria, a total of 36 ATP is produced, if they give it to NAD a total of 38 ATP is produced.
      Hope this helped. 🙂

    • #26498
      victor
      Participant

      Usually my book use a malate dehydrogenase pathway in the Krebs cycle..so, I’ve just known that there’re 2 pathways…thanks Ozge.. 😆

    • #26523
      Poison
      Participant

      You’re welcome. 🙂

    • #26535
      Dr.Stein
      Participant

      Different cells will generate different amount of ATP. Some cells can generate 36 ATP whereas another cells generate 38 ATP depends on the type of cells and their activities. For instance muscle cells generate 38 ATP, gland cells only 36 ATP.

    • #29794
      victor
      Participant
      quote Dr.Stein:

      Different cells will generate different amount of ATP. Some cells can generate 36 ATP whereas another cells generate 38 ATP depends on the type of cells and their activities. For instance muscle cells generate 38 ATP, gland cells only 36 ATP.

      I’ve read in some books and they said that the difference between 36 ATP and 38 ATP is based on the prokaryotic and Eukaryotic cell. Eukaryotic cell produced 36 ATP because in the Glycolysis, 4H+ is taken by protein carrier named 2 NAD+ to form NADH+H to the ETS. But, during the way from Cytoplasm to mitochondrion cristae, NADH+H is converted into FADH2 and get processed just the same like other FADH2.
      so: Glycolysis = 2 ATP (net) + 2 FADH2
      Krebs = 2 ATP + 8 [NADH+H] + 2 FADH2
      Total NADH+H = 8 x 3 ATP = 24 ATP
      Total FADH2 = 4 x 2 ATP = 8 ATP
      Others = 4 ATP = 4 ATP
      whole ATP from 1 molecule Glucose = 36 ATP

      While in prokaryotic cell, NADH+H doesn’t converted into FADH2 durinf transport..so, they produce 38 ATP.

      That’s what I read
      Victor

    • #29854
      sdekivit
      Participant
      quote Dr.Stein:

      Different cells will generate different amount of ATP. Some cells can generate 36 ATP whereas another cells generate 38 ATP depends on the type of cells and their activities. For instance muscle cells generate 38 ATP, gland cells only 36 ATP.

      it’s due to the malate/aspartate shuttle.

    • #29890
      MrMistery
      Participant

      @victor
      I don’t think so…. 😀

    • #29928
      victor
      Participant

      Any reason Andrew??well, that’s based on my bio book… 😀

    • #29939
      sdekivit
      Participant
      quote victor:

      Any reason Andrew??well, that’s based on my bio book… 😀

      then it’s wrong, because it’s 30 or 32 ATP

    • #29955
      MrMistery
      Participant
      quote :

      I’ve read in some books and they said that the difference between 36 ATP and 38 ATP is based on the prokaryotic and Eukaryotic cell

      This is what i meant. why? because i know otherwise 😀 Even in the human body, you can find both kinds of cells, depending on which methabolic pathway the reactions follow. i think Dr.Stein gave an example…

    • #30007
      victor
      Participant

      Um, quite confused actually but let me write it down once more.
      we get 2 ATPs and 2FADH2 from glycolysis = total 6 ATPs.
      we get 2 ATPs, 8 NADH+H and 2 FADH2 from Krebs = total 30 ATPs.
      if all of the ATPs are summarized, it will be 36 ATPs right? (it’s in eukaryotic)

      If in prokaryotic:
      we get 2 ATPs and 2 NADH+H = total 8 ATPs
      we get 2 ATPs, 8 NADH+H and 2 FADH2 from Krebs = total 30 ATPs.
      if all of the ATPs are summarized, it will be 38 ATPs right?

      so?
      I know, I haven’t reach the more complicated stuff of BioChem but at least..is these right?

    • #31619
      jeffrey
      Participant

      my friend, generally, for making 1 ATP cells have to use 3 H+, 2 electrons can pump 10 protons, further information in the book<<color atlas of biochemistry>> chapter of ATP synthesis

    • #31737
      Morris
      Participant

      The transporter used in electron transport is NADH; Krebs cicle generates 6NADH; because to ossidate a glucose molecole are nedded two Krebs cicle, the total production of NADH is 12.
      In the elctron transport every NADH produces 3ATP; so after electron transport are generated 36 molecules.
      The total balance of aerobic metabolism is 38 ATP (2 ATP from glicolisis + 36 ATP from electron transpor = 38 ).

    • #82379
      kittenkat10221964
      Participant

      I need to figure out how many molecules of Nad+ are reduced to form NADH for each molecule of pyruvic acid that enters the Krebs Cycle?

    • #82418
      MrMistery
      Participant

      google images for "krebs cycle" and you will get your answer

    • #114073
      neutron55
      Participant

      i m gonna answer victor’s question..
      actually each NADH produced in glycolysis….produces 2 instead of 3ATPs…and it is called substrate level phosphorylation…because oxygen is not involved in it….hence the 2NADHs produced in glycolysis produces 4 ATPs…and i think total ATPs produced in glycolysis are 6…now u can easily get the result of net gain of 36 ATPs instead of 38 ATPs…ok…

      YOUR PROBLEM SOLVED HERE…

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