Biology Forum Molecular Biology new dna form

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    • #2067
      lara
      Participant

      read that p-form of dna(in vitro) has the phosphates facin’ inwards,any idea???

    • #30400
      MrMistery
      Participant

      I have never heard of the p-form of DNA. I know B-form(natural), A-form and Z-form but P-form? Sorry, can’t help…

    • #30465
      hurly
      Participant

      Care to explain what all of these X-forms are…? 😕

    • #30528
      MrMistery
      Participant

      In a transversal section:
      A-form: there is a central empty space, sugars and phosphates are at the margns and the nitrogen bases are towards the center
      B-form: nitrogen bases are towards the center and the phosphates and sugars towards the margins(outside) of the macromolecule. The centre is filled with the nitrogen bases, there is no space
      Z-form: appears as the compenents were distributed all around the matrix of the helix, with no specific domains. Actually the sugars and phosphates are towards the centre and the N bases on the outside.
      Is this enough info or do you need more? cause i am lazy and do not want to write things without a point..

    • #30531
      hurly
      Participant

      Thanks for taking time explaining it to me 😀

    • #30563
      ak537
      Participant

      can you please elaborate p-form of DNA then I might be able to say something 🙂

    • #30588
      lara
      Participant

      allright.p-form is found in vitro,on artificial xtension.this is all i know.can u make out sumthin’ of it?? 😆

    • #30618
      Chris4
      Participant
      quote lara:

      allright.p-form is found in vitro,on artificial xtension.this is all i know.can u make out sumthin’ of it?? 😆

      DNA undergoes a stretching phase transition at a force of 65 pN; above this force, DNA is thought to take the form that Linus Pauling originally hypothesized, with the phosphates in the middle and bases splayed outward. This proposed structure for overstretched DNA has been called “P-form DNA,” in honor of Pauling.

      From: http://en.wikipedia.org/wiki/Mechanical … ies_of_DNA

    • #30636
      ak537
      Participant

      thanks for such a nice explation about P form.

    • #30950
      lara
      Participant

      what’s the idea of bases splaying outwards?can we still call it dna??

    • #30976
      MrMistery
      Participant

      Sure we can, just another type of DNA

    • #31036
      lara
      Participant

      what about the H-bonds between the bases ,then??

    • #31070
      MrMistery
      Participant

      That is only in B-form, which is natural…

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