new dna form

October 4, 2005 at 9:51 am #2067

lara

Participant

read that p-form of dna(in vitro) has the phosphates facin’ inwards,any idea???

October 4, 2005 at 7:21 pm #30400

MrMistery

Participant

I have never heard of the p-form of DNA. I know B-form(natural), A-form and Z-form but P-form? Sorry, can’t help…

October 5, 2005 at 3:59 pm #30465

hurly

Participant

Care to explain what all of these X-forms are…? 😕

October 6, 2005 at 7:28 pm #30528

MrMistery

Participant

In a transversal section:
A-form: there is a central empty space, sugars and phosphates are at the margns and the nitrogen bases are towards the center
B-form: nitrogen bases are towards the center and the phosphates and sugars towards the margins(outside) of the macromolecule. The centre is filled with the nitrogen bases, there is no space
Z-form: appears as the compenents were distributed all around the matrix of the helix, with no specific domains. Actually the sugars and phosphates are towards the centre and the N bases on the outside.
Is this enough info or do you need more? cause i am lazy and do not want to write things without a point..

October 6, 2005 at 7:47 pm #30531

hurly

Participant

Thanks for taking time explaining it to me 😀

October 7, 2005 at 12:01 pm #30563

ak537

Participant

can you please elaborate p-form of DNA then I might be able to say something 🙂

October 7, 2005 at 4:50 pm #30588

lara

Participant

allright.p-form is found in vitro,on artificial xtension.this is all i know.can u make out sumthin’ of it?? 😆

October 8, 2005 at 12:19 am #30618

Chris4

Participant

quote lara:

allright.p-form is found in vitro,on artificial xtension.this is all i know.can u make out sumthin’ of it?? 😆

DNA undergoes a stretching phase transition at a force of 65 pN; above this force, DNA is thought to take the form that Linus Pauling originally hypothesized, with the phosphates in the middle and bases splayed outward. This proposed structure for overstretched DNA has been called “P-form DNA,” in honor of Pauling.

From: http://en.wikipedia.org/wiki/Mechanical … ies_of_DNA

October 8, 2005 at 12:11 pm #30636

ak537

Participant

thanks for such a nice explation about P form.

October 15, 2005 at 10:39 am #30950

lara

Participant

what’s the idea of bases splaying outwards?can we still call it dna??

October 15, 2005 at 6:16 pm #30976

MrMistery

Participant