There has been a lot of discussion about open access and peer review recently. In addition to open access and pre-publication review, a forum to openly discuss research after it has been published is needed. That is why I think this new and free site PubMed Wizard (http://www.biowizard.com/search.aspx) is great. It lets you Rank and Discuss all your favorite papers. You can Discuss ANY paper found in the PubMed database, all 16 million of them! You can also Save interesting papers to your personal folder and Share them with friends. In addition, you can see what everyone else is reading by following the Most Viewed and Top Ranked papers. The site also hosts a social network for life scientists, Lab Wizard. Take a look at BioWizard (http://www.biowizard.com).