Biology Forum Cell Biology Please comment this theory, is this theory correct?

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    • #17485
      schang1984
      Participant

      I made a theory that explains how flavonoids kill cancer cells without harming normal cells.

      Quercetin is an antioxidant. It neutralizes free radicals. While doing so this quercetin changes to a radical molecule. For example it neutralizes 4 radical molecules and becomes a radical molecule with 4 radicals.

      Then it sticks to DNA (covalent binding). Because there is no water present there, it stays a radical molecule.

      When a cell divides, water nears this molecule so it reacts with water causing OH radicals killing the cell.

      Normal cells always repair their entire DNA before cell division, so the radical flavonoid molecule is removed. So normal cells stay unharmed.

      Cancer cells divide before they have repaired their entire DNA, so they die.

      So it’s actually a bomb.

      A flavonoid molecule is like a bomb that explodes if it’s not removed before a cell tries to divide. Cancer cells that divide before reperation die, because the bomb isn’t removed, so it explodes when the cell tries to divide. Normal cells that divide after reperation remove the bomb so they live.

      Cancer cells that do completely repair their DNA before cell division aren’t cancer cells anymore (they are normal cells) because they have to wait a long time before cell division.

      Normal cells that did not completely repair their DNA before cell division can pass a mutation down to daughter cells.

      So flavonoids kill only cancer cells but no normal cells.

      It’s like this:

      Normal cell -> completely repaired -> flavonoid bomb removed -> cell divides normal

      Cancer cell -> not completely repaired -> flavonoid bomb detonates -> cell killed while it was dividing.

      Cancer cell that completely repairs = normal cell.

      copyright © 2007 Steven Chang, All Rights Reserved.

      Please comment on this theory, is it correct?

    • #114184
      JackBean
      Participant

      so you have a theory since 2007 and you publish it in 2013 on internet forum, where anybody can take it?

      Few things:
      1) it will not have 4 radicals on one molecule, it’s always just one radical electron
      2) the water is everywhere!

    • #114187
      schang1984
      Participant

      Thank you for your answer.

      1) I wonder how it is possible then that ascorbic acid can lose 2 electrons and then have 2 free radicals at the same time.

      2) The water is everywhere, but the idea is that DNA is hydrophobic so it pushes the water away. However, when it divides, the 2 DNA strands seperate and then it loses it’s hydrophobic properties.

      My theory is put online on my website yes and I put it here too. If it may help cancer patients it should be published right? Maybe others can improve that theory and then one day the cure against cancer will be found.

      I have a website which hosts an alternative cancer treatment protocol, using the compounds quercetin + ascorbic acid + free radicals:

      http://www.acancer.info/

      Unfortunately, the results are not as good as I expected and I don’t know why. Can you find out? I thought maybe the quality of the quercetin supplements are not good enough? Or there are bioavailability issues?

    • #114189
      JackBean
      Participant

      Results not good? Maybe because the theory is wrong?

    • #114222
      adithya528
      Participant

      i have gone through your theory its really good but can you explain hoe the DNA ant he flavnoid quercetin occurs exactly ??? ❗

    • #114234
      schang1984
      Participant

      The theory is that the radical flavonoid (like quercetin) molecule forms a DNA adduct, like mutagenic substances form a DNA adduct and causes DNA to be misread which causes mutation in daughter cells. Radical molecules have the ability to covalently bind to DNA, which makes it able for the radical flavonoid to form adducts on DNA.

      Then, if the DNA adduct isn’t removed before cell division and cell division takes place, the radical flavonoid molecule reacts with water, causing OH radicals, making the DNA unreadable, killing the cell while it was trying to divide.

      Where the adducts are formed on DNA exactly I do not know, because there isn’t any research done into this.

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