Please help! Question regarding microsatellite DNA.

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    • October 4, 2009 at 5:15 am #11933
      RoseLevin
      Participant

      Which of the following is true for microsatellite loci?

      a. are typically found in centromeres and telomeres
      b. are typically made up of 1-4 bp repeat units
      c. can be made up of tandemly arranged rRNA genes
      d. can decrease in unit number during DNA replication
      e. two of the above

      I believe b is true…but can someone give me their opinion for d??
      Thanks so much

    • October 4, 2009 at 3:52 pm #93348
      MrMistery
      Participant

      i would have said d is false, as i thought they can only increase (like in fragile X syndrome). However, according to wikipedia they can also decrease in number http://en.wikipedia.org/wiki/Microsatellite_instability

    • October 4, 2009 at 4:20 pm #93349
      RoseLevin
      Participant

      Ok…I thought that they could decrease. But I’m stuck on the wording…could it mean anything? Is there a difference between unit number and repeat number?

    • October 5, 2009 at 3:30 am #93354
      MrMistery
      Participant

      i don’t think so (though I am not an english native speaker, so wording is not my thing…).

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