Viewing 5 reply threads
  • Author
    Posts
    • #14985
      Adz795
      Participant

      I have come across these terms: homodimer, heteromer, hexamer,etc. I don’t quite understand what they mean. I would appreciate it if you could explain me in detail the significance of these terms. You may also do by just posting a link so that I’ll read it myself. I couldn’t find it online the relevant data related to these terms.

      I also want to know what happens when proteins are treated with Mercaptoethanol, urea, etc.
      Thank you.

    • #104981
      canalon
      Participant

      Basically learn greek.
      Homo: same
      Hetero: different
      di: 2
      hexa: 6
      Mer (actually not sure if the root is greek for that one): unit
      Homo di mer: same 2 units is aprotein made of 2 identical subunits
      Hetero di mer: 2 different units

    • #104982
      Adz795
      Participant

      So with "-mer" you mean a subunit? That is a polypeptide?
      Also, what is the difference between: protein domain, polypeptide, subunit.
      I guess all the three words mean the same.

    • #104985
      canalon
      Participant

      Protein domain: A portion of a protein usually defined by a specific function (zinc finger or some such). There might be more than one domain in one polypeptide.
      Polypeptide: a large chain of amino acids, but not a protein.
      Subunit: usually one of the many polypeptide composing a protein

    • #104991
      vinayaksabnis
      Participant

      In case of protein with alcohol it will denature the side chains affecting hydrogen bondings while in case of protein with urea will affect covalent bonds and urea is a powerful denaturant than alcohol

    • #105008
      JackBean
      Participant

      1) are you sure, that urea will disrupt covalent bonds? I highly doubt, since such denatured proteins can be renatured after dialysis.
      2) how is that related to the topic? 🙄

Viewing 5 reply threads
  • You must be logged in to reply to this topic.