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    • #7607
      fluktuacia
      Participant

      Are mature RBC capable of protein production when they do not have nucleus? How are they able to transcribe RNA for protein production (they need new proteins.. to repair etc. right?).
      And similarly when primary oocyte stops its division at diplotene stage is it capable of transcribtion? if not, how it creates RNA and proteins?

    • #72420
      david23
      Participant

      mature RBC do not have nucleus, so they cant transcribe or translate. All the proteins they need are made before they become mature.

    • #72484
      fluktuacia
      Participant

      and the proteins they have made before maturation is sufficient to supply their function? aren’t there different sources of proteins or other ways of their production?
      and what about that primary oocyte?

    • #72490
      Darby
      Participant

      An RBC is pretty much just a bag of hemoglobin anyway – not a lot of metabolic processes there.

      Not sure about the oocyte, but I know enough to know NOT to apply "rules" of what can and can’t happen at certain times to real-world biological systems. Biology is a system of exceptions.

    • #72549
      david23
      Participant

      RBC make everything they need before fully functioning, and then get rid of their nucleus.

      About primary oocyte, are you perhaps thinking that since the chromosomes are so tightly wound, that they cant be used to produce proteins? There are regulatory proteins that allow transcription to happen. Am I knocking up the right tree here?

    • #72576
      Revenged
      Participant

      I can’t think of a reason why a primary oocyte won’t be able to undergo transciption…

    • #72588
      david23
      Participant

      fluk u need to give some feedbacks so i can know how to answer u

    • #72644
      fluktuacia
      Participant

      sorry i wasn’t here at the weekend:).. well, i agree with those RBC (i have the same explanation, i was just doubtful whether RBC can survive just with the proteins made before the maturation)
      what i meant in the case of the oocyte was, that during division the transcribtion is halted and since the primary oocyte stops at the middle of it (diplotene stage) proteine production shoud be stopped as well.. so the same problem as in RBC – how it can survive for years withouth protein production

    • #72654
      kotoreru
      Participant

      Erythrocytes do not survive for years. I actually think the average life expectance is 3 weeks?

    • #72659
      Dustfinger
      Participant
      quote kotoreru:

      I actually think the average life expectance is 3 weeks?

      Not 120 days ???

    • #72681
      david23
      Participant

      everything made to survive those 120 days is made beforehand.

    • #72684
      Poison
      Participant
      quote Dustfinger:

      quote kotoreru:

      I actually think the average life expectance is 3 weeks?

      Not 120 days ???

      yes 120 days.

    • #72689
      david23
      Participant

      if you are willing to donate some time to look up all the proteins in a RBC, maybe we can then find out their half life which can probably answer your question better.

    • #73584
      fluktuacia
      Participant

      ok.. and i have another question concerning RBC. What is the function of the antibodies expressed on their surface (ABO system) and are there any functional differences btw. the antibodies of different blood groups?

    • #73589
      david23
      Participant

      antigens, not antibodies. a different antigen from a donor that the host body isnt used to will result an immediate immunological response, and thats caused by the antibodies

    • #73616
      fluktuacia
      Participant

      yes.. i ment antigens:) and i know that they cause the immunological response when blood of different type is donated, but that is their primary function? do the antigens cause response in the presence of some other substances than donor blood:) ?

    • #73644
      david23
      Participant

      no studies have been done that suggest so. Just a bunch of antigens

    • #73646
      fluktuacia
      Participant

      ok…anyway..thanx a lot:)

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