- May 9, 2007 at 5:28 am #7607
Are mature RBC capable of protein production when they do not have nucleus? How are they able to transcribe RNA for protein production (they need new proteins.. to repair etc. right?).
And similarly when primary oocyte stops its division at diplotene stage is it capable of transcribtion? if not, how it creates RNA and proteins?
- May 9, 2007 at 9:23 am #72420
mature RBC do not have nucleus, so they cant transcribe or translate. All the proteins they need are made before they become mature.
- May 10, 2007 at 9:11 am #72484
and the proteins they have made before maturation is sufficient to supply their function? aren’t there different sources of proteins or other ways of their production?
and what about that primary oocyte?
- May 10, 2007 at 3:16 pm #72490DarbyParticipant
An RBC is pretty much just a bag of hemoglobin anyway – not a lot of metabolic processes there.
Not sure about the oocyte, but I know enough to know NOT to apply "rules" of what can and can’t happen at certain times to real-world biological systems. Biology is a system of exceptions.
- May 11, 2007 at 3:51 pm #72549
RBC make everything they need before fully functioning, and then get rid of their nucleus.
About primary oocyte, are you perhaps thinking that since the chromosomes are so tightly wound, that they cant be used to produce proteins? There are regulatory proteins that allow transcription to happen. Am I knocking up the right tree here?
- May 11, 2007 at 11:23 pm #72576RevengedParticipant
I can’t think of a reason why a primary oocyte won’t be able to undergo transciption…
- May 12, 2007 at 7:07 pm #72588
fluk u need to give some feedbacks so i can know how to answer u
- May 14, 2007 at 6:50 am #72644
sorry i wasn’t here at the weekend:).. well, i agree with those RBC (i have the same explanation, i was just doubtful whether RBC can survive just with the proteins made before the maturation)
what i meant in the case of the oocyte was, that during division the transcribtion is halted and since the primary oocyte stops at the middle of it (diplotene stage) proteine production shoud be stopped as well.. so the same problem as in RBC – how it can survive for years withouth protein production
- May 14, 2007 at 8:01 am #72654kotoreruParticipant
Erythrocytes do not survive for years. I actually think the average life expectance is 3 weeks?
- May 14, 2007 at 11:07 am #72659DustfingerParticipantquote kotoreru:
Not 120 days ???
- May 14, 2007 at 7:24 pm #72681
everything made to survive those 120 days is made beforehand.
- May 14, 2007 at 8:00 pm #72684PoisonParticipantquote Dustfinger:
yes 120 days.
- May 14, 2007 at 8:27 pm #72689
if you are willing to donate some time to look up all the proteins in a RBC, maybe we can then find out their half life which can probably answer your question better.
- June 6, 2007 at 5:17 am #73584
ok.. and i have another question concerning RBC. What is the function of the antibodies expressed on their surface (ABO system) and are there any functional differences btw. the antibodies of different blood groups?
- June 6, 2007 at 11:15 am #73589
antigens, not antibodies. a different antigen from a donor that the host body isnt used to will result an immediate immunological response, and thats caused by the antibodies
- June 7, 2007 at 5:28 am #73616
yes.. i ment antigens:) and i know that they cause the immunological response when blood of different type is donated, but that is their primary function? do the antigens cause response in the presence of some other substances than donor blood:) ?
- June 8, 2007 at 2:48 pm #73644
no studies have been done that suggest so. Just a bunch of antigens
- June 8, 2007 at 4:26 pm #73646
ok…anyway..thanx a lot:)
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