New research shows that decreasing the levels of the SET protein can reawaken the tumor suppressor protein p53, providing a potential way to combat cancer.
p53 is described as the guardian angel of the genome because of its key role in suppressing tumor formation. Mutations in p53 occur in around half of all human tumors. These mutations probably facilitate tumor formation. Some scientists believe that if p53 is simply inactive, reawakening it may be a method of preventing cancer from developing. This study showed that reducing the SET protein increased the activity of p53 in human cancer cells. Moreover, tumors grow faster when SET is present. If you want to read more, refer to http://about.cusabio.com/c-19799.html