Obesity is a fast growing problem in many regions of the world. The brain has been linked to obesity development. However, the exact mechanism of how an unhealthy diet alters the brain and thus leads to body fat accumulation remains unclear.
Now, a study has revealed a novel mechanism involving the Rap1 gene in the brain that modulates obesity, providing a potential therapeutic target for the intervention of obesity. Researchers found that the mice without the Rap 1 gene had significantly reduced body weight, when they were given a high fat diet. More details, please visit: http://about.cusabio.com/c-19798.html