- November 23, 2011 at 1:43 pm #15727
I do not understand what is meant by splice isoforms. I used to think that they are the products of alternate splicing.
But I was reading a paper on:
"mTORbeta Splicing Isoform Promotes Cell Proliferation and Tumorigenesis"
And I got confused and decided to get the basic definition right. Google wasnt very helpful either.
What does the title refer to?
1. the product (mRNA) of alternate splicing OR
2. the product (protein) of translation of already spliced mRNA
Thank you so much.
- November 23, 2011 at 4:46 pm #108338JackBeanParticipant
product of alternative splicing leads to alternative protein isoforms, doesn’t it?
- November 23, 2011 at 7:28 pm #108349
I am not very sure now it seems so. But yes a clarification would help.
Thanks though. 🙂
- November 28, 2011 at 7:18 pm #108471cw11Participant
I did a quick google search and it seems that isoforms typically refer to proteins, so I believe the correct answer would be (2) – the protein product of already-spliced mRNA.
- November 28, 2011 at 7:19 pm #108472
Seemed so to me too. Thank you so much 🙂
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