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    • #15727
      jwalin
      Participant

      I do not understand what is meant by splice isoforms. I used to think that they are the products of alternate splicing.
      But I was reading a paper on:
      "mTORbeta Splicing Isoform Promotes Cell Proliferation and Tumorigenesis"
      And I got confused and decided to get the basic definition right. Google wasnt very helpful either.
      What does the title refer to?
      1. the product (mRNA) of alternate splicing OR
      2. the product (protein) of translation of already spliced mRNA

      Thank you so much.
      🙂

    • #108338
      JackBean
      Participant

      product of alternative splicing leads to alternative protein isoforms, doesn’t it?

    • #108349
      jwalin
      Participant

      I am not very sure now it seems so. But yes a clarification would help.
      Thanks though. 🙂

    • #108471
      cw11
      Participant

      I did a quick google search and it seems that isoforms typically refer to proteins, so I believe the correct answer would be (2) – the protein product of already-spliced mRNA.

    • #108472
      jwalin
      Participant

      Seemed so to me too. Thank you so much 🙂

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