Biology Forum Genetics …..

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    • #11962
      schnupps12
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      ….

    • #93458
      zami’87.
      Participant

      Let me see..if I remember well genetic classes 🙂

      Write given phenotypes in form of received genotypes from female gametes:

      Dy+*ct+*w+ 18
      dy*ct+*w+ 153
      dy+*ct*w+ 6
      dy+*ct+*w 76
      dy+*ct*w 150
      dy*ct*w+ 72
      dy*ct*w 22
      dy*ct+*w 3
      total: 500
      Parental class is the biggest.So dy*ct+*w+ 153 and dy+*ct*w 150 don’t have recombinations. Note classes with least individuals 3 and 6. Those are double crossing overs.Gene in the middle switches. So w gene is in the middle.So correct orders on two X chromosomes are Dy*w+*ct+ and dy+*w*ct . Next calculate recombinant frequency by dividing (number of recombinants for each gene pair) with (total number). For example distance in m.u between genes w and ct is..(search w*ct+ and w+*ct pairs in classes..forget dy gene for now) 100*(6+76+72+3)/500=100* 0.314=31.4 m.u and by calculating in similar fashion distance between dy+ and w(or dy*w+) is 9.8 m.u. If you check distance between dy+ and ct you’ll notice that you’ll get smaller number than by summing 9.8+31.4 . Why?Because you forgot about double crossingovers that in this case you add twice. Next calculate interference by using formula I=1-(observed doublerecombinants/expected recombinants).Observed double recombinants are 6 + 3 as I said. Expected are..product of frequencies in individual regions..thus (0.314*0.098)*500=15.386..I=1-9/15.386=0.4151 or 41.5 %..hope this helped.Cheers! 🙂

      ps feel free to correct me..

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