the n and c terminus - Biology Forum

last updated by

JackBean 14 years, 7 months ago

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- April 27, 2010 at 12:48 pm #13213
  llyneth28
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  Why are the amino acids near the n and c terminus of proteins difficult to resolve by x-ray crystallography.
- April 27, 2010 at 1:47 pm #99379
  JackBean
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  because the ends are usually at the surface of the protein and are flexible and thus "invisible" for X-ray. It’s similar like whit some loops, which are disordered until the substrate is bound 😉
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