Surfing the web, I found an interesting picture that I’ve posted as attachment.
The image shows the cellular organization of chromosomes in the nucleus; you can observe that in the interchromatin space there is a transcription factory (in the picture: RNA transcripts) ,while around this region there are more than one active locus( of different chromosomes).Then,since the chromosomes are so close ,could happen that a traslocation appear between these active loci ?

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Attachments:

This research should be interesting ,if you want to read it : http://www.sciencedirect.com/science/article/pii/S0092867407001262

In the article there is also a paragraph about traslocation,what do you think?

thank for posting these researches,I’ve found them satisfying