Tripeptide in organic solvent

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    • #12231
      PimpleMan
      Participant

      I have two non-polar amino acids and I am trying to determine which would be most likely to be soluble in an hydrophobic organic solvent. The third option is either proline or glycine. Which would be the most hydrophobic? From my text book and the internet they both appear to have the ability to form hydrophobic tripeptides.

    • #94635
      JackBean
      Participant

      1) and will you tell us, which amino acids you have?
      2) althrough the side chain may be nonpolar, the NH2-C(alpha)-COOH is not

    • #94637
      PimpleMan
      Participant

      I going to say that phenylalanine, alanine, glycine would be the most likely to be soluble. Thanks for your advice.

    • #94638
      JackBean
      Participant

      You’re welcome 😆

      Why not L or I?

      I would be so sure about F, there is some trick, when comparing F and Y. Unfortunatelly, I don’t remember, what was it 🙁

    • #94639
      PimpleMan
      Participant

      My assignments are all question which require I draw on knowledge that is not present in my textbook, which makes it fairly confusing at best. Does anyone know a good website for cell bio, or more specifically how I could determine which amino acid sequence would be the most soluble in a (hydrophobic) organic solvent such as benzene? (Or I might have myself, if this has anything to with adding up hydropathy)

    • #94641
      JackBean
      Participant

      1) do you really think, that you will find better info on inthernet instead of in book? 🙄
      2) if you said benzene immediatelly, than it’s sure to use as much aromatic AAs (F, Y, W) as possible 😉

    • #94645
      PimpleMan
      Participant
      quote JackBean:

      1) do you really think, that you will find better info on inthernet instead of in book? 🙄
      2) if you said benzene immediatelly, than it’s sure to use as much aromatic AAs (F, Y, W) as possible 😉

      I only have introductory organic chemistry knowledge. I’m wondering if Cell Biology requires a bit more than that?

    • #94661
      JackBean
      Participant

      not really 🙂 Depends, how much you wish to be good and how much are are able to learn at time, when you need it 😉

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