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    • #13027
      raji
      Participant

      for a protein in a cell, what does "turnover" mean? for example, when you say "turnover of protein A is larger than that of protein B", what does this mean? dose it have anything with biochemistry as well?
      thanks

    • #98711
      jwalin
      Participant

      most probably it means that the total output of protien A is larger than the toatl output of protien B
      99% this is right

    • #98712
      JackBean
      Participant

      output? And what is output?

    • #98714
      jwalin
      Participant

      output as in production… as in the amount that is produced

    • #98716
      JackBean
      Participant

      than you’re wrong 😛

      turnover means the net of synthesis and degradation, defining the half-life of protein.
      Higher turnover probably means, that the protein is synthesised and degraded faster
      http://sandwalk.blogspot.com/2007/06/pr … nover.html

    • #98745
      jwalin
      Participant

      ohk…
      mmm… :S
      the word net suggests…
      amount produced – amount degraded

      while the third line suggests
      amount produced + amount degraded

      sorry but i got a little confused…
      which one is the right one ❓

    • #98751
      mith
      Participant

      It’s not describing the total amounts, it’s describing the rates of production and degradation.

    • #98765
      david23
      Participant

      Yeah turn over, half lives, it’s just a description of how long it will stay around before it can no longer be detected or functional. It’s usually measured as a time value but you can make it a rate thing. Like the RBC turns over every 120 days or this drug’s half life is 5 hours.

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