1) When they’re synthesized by cytosolic ribosomes?
2) When they’re synthesized by ER bound ribosomes?
So in (2), will the holoprotein travel through the Golgi for further modifications or will the individual subunits (or complexes of a few subunits) travel through it and then finally be brought together… where?
Thanks in advance!
– if you have any link references, please post 😉
I do not know the general answer. However for transcription factors which are active through their quaternary structure this quaternary structure can only be obtained when activation by signal transmission pathways is realized. I therefore assume that monomers are already synthetized and that their later activation will allow the quaternary structure to be formed.