A simple problem - Biology Forum

last updated by

JackBean 14 years, 4 months ago

4 voices

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- June 25, 2010 at 3:05 pm #13485
  biostud
  Participant
  Well, we know that during DNA replication there is 1 mistake per 10^9 bases per generation. Well lets suppose we have a gene that contains 10^3 bases. In how many generations there will be one mutation? I think in 10^6 generations! Am i correct? ❓
- June 29, 2010 at 7:20 pm #100357
  mith
  Participant
  those are probabilities fyi, so it’s not 1 mistake per 10^9, it’s on average 1 mistake per 10^9.
- July 1, 2010 at 3:38 pm #100373
  hashemyemen
  Participant
  simply, all those mistakes are then repaired.
  Almost 1 mistake per 10,000,000 is taking place while DNA replication according to the book of Brooker ( Principles of Genetics ).
  Check it out 😀
- July 3, 2010 at 1:04 am #100384
  JackBean
  Participant
  hashem, hashem, you’re talking, well, stupid things again…
  Definitely not all the mistakes are repeaired (what about evolution?), but the repair systems increase the efficiency by factor of 100 (with Pol’s proof-reading of 100 as well)
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