A simple problem

[biostud]

Well, we know that during DNA replication there is 1 mistake per 10^9 bases per generation. Well lets suppose we have a gene that contains 10^3 bases. In how many generations there will be one mutation? I think in 10^6 generations! Am i correct? ❓

[mith]

those are probabilities fyi, so it’s not 1 mistake per 10^9, it’s on average 1 mistake per 10^9.

[hashemyemen]

simply, all those mistakes are then repaired.
Almost 1 mistake per 10,000,000 is taking place while DNA replication according to the book of Brooker ( Principles of Genetics ).

Check it out 😀

[JackBean]

hashem, hashem, you’re talking, well, stupid things again…
Definitely not all the mistakes are repeaired (what about evolution?), but the repair systems increase the efficiency by factor of 100 (with Pol’s proof-reading of 100 as well)

[Author]

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