I don’t understand why a person with type A can donate blood to type A or AB ppl, but receive blood from type A or O ppl. Here are my questions:
1) Since type A ppl have antigen A on their red blood cells and anti-B antibodies, when they donate their blood to type AB ppl, wouldn’t the anti-B antibodies bind to the B antigen on the AB red blood cells and agglutinate?
2) When a type A person receives blood a type O person, since the type O has anti-A and anti-B antibodies, wouldn’t the anti-A antibodies bind to the antigen A on the red blood cell and agglutinate?
3) When we are donating blood, are we donating only the red blood cell (with antigen on it) and no antibodies?
I answer just in your first question. I think that will be enough.
Yes, you are right saying that anti-B antibodies bind to B antigen on the AB red blood cells. Say, the donor of type A gives 1 liter a blood. The concentration of anti-B antibodies is pretty small in 1 liter of blood that would be triggered dangerous an agglutination. Clear?
