Biology Forum › Cell Biology › Blood Type
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- August 13, 2008 at 7:57 pm #9956
MarukoParticipantHi,
I don’t understand why a person with type A can donate blood to type A or AB ppl, but receive blood from type A or O ppl. Here are my questions:
1) Since type A ppl have antigen A on their red blood cells and anti-B antibodies, when they donate their blood to type AB ppl, wouldn’t the anti-B antibodies bind to the B antigen on the AB red blood cells and agglutinate?
2) When a type A person receives blood a type O person, since the type O has anti-A and anti-B antibodies, wouldn’t the anti-A antibodies bind to the antigen A on the red blood cell and agglutinate?
3) When we are donating blood, are we donating only the red blood cell (with antigen on it) and no antibodies?
Thanks in advance!
Maruko
- August 13, 2008 at 9:32 pm #85500MisterATPParticipant
I answer just in your first question. I think that will be enough.
Yes, you are right saying that anti-B antibodies bind to B antigen on the AB red blood cells. Say, the donor of type A gives 1 liter a blood. The concentration of anti-B antibodies is pretty small in 1 liter of blood that would be triggered dangerous an agglutination. Clear?
- August 14, 2008 at 12:58 am #85503MarukoParticipant
Thank you so much, MisterATP!
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