No. Because the viral RNA retrovirus is run in reverse. The cells are already infected with the virus. It directs the cell to produce a DNA gene sequence from the viral RNA template.

We have to provide more sophisticated "education" to those stem cells against "smart" HIV 😕

How about mutating those T-cells so that they never have CCR5 receptor. Then HIV won’t enter the T-cells..:lol:

@victor
the idea is nice…but it is going to be really hard to achieve that, i guess

what physiological effects are due to absence of the CCR5 ?

Well, if engineering CD4+ is hard, I think we need to educate macrophage much better. It helps HIV to meet CD4+ 😈

@Dr.Stein
hmm….I think that macrophage also act like innocent cells when it meets with HIV. Um…like commonly cells, HIV will enter macrophage via CXCR4 receptor, so how could we educate those macrophage?

@sdekivit
In my book (JMAMMB), it discusses about HIV profile and it’s written that a patient with mutation on the T-Cell (CCR5 receptor) is immune to AIDS. Then the book doesn’t write anything about the bad effect of this mutation.

JMAMMB = Jawetz, Melnick & Adelberg’s Medical Microbiology. Written By Geo F. Brooks, Janet S. Mutel, and friends…:mrgreen:

That’s it. It should not be that innocent! 😈