Biology Forum › Molecular Biology › DNA Gyrase vs. DNA Helicase
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- November 29, 2005 at 2:10 am #2692jaysonParticipant
What is the difference between the two ? (not structurelly (sp?), but by function)
Thanks in advance.
- November 29, 2005 at 8:58 pm #33826sdekivitParticipant
DNA gyrase produces DNA supercoiling and DNA helicase unwinds DNA
- November 29, 2005 at 8:58 pm #33827jaysonParticipant
Doesn’t Gyrase also relive the tension from the DNA strand.
- November 30, 2005 at 1:37 am #33859JenniferParticipant
DNA helicase unwinds the double helix by disrupting the hydrogen bonds of the base pairs of nucleotides. DNA gyrase relieves the tension from the unwinding of the double helix by cutting the strand, and reannealing it once the tension has been released.
- November 30, 2005 at 3:32 pm #33905sdekivitParticipant
NOOOOOOO!!!!!! DNA gyrase = DNA topoisomerase II and produces negative supercoils
–> DNA topoisomerase I relaxes these negative supercoils.
DNA helicase pulls the DNA strands away from each other for transcription and is completely different from producing/relaxing supercoils
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