Biology Forum Molecular Biology DNA Gyrase vs. DNA Helicase

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    • #2692
      jayson
      Participant

      What is the difference between the two ? (not structurelly (sp?), but by function)

      Thanks in advance.

    • #33826
      sdekivit
      Participant

      DNA gyrase produces DNA supercoiling and DNA helicase unwinds DNA

    • #33827
      jayson
      Participant

      Doesn’t Gyrase also relive the tension from the DNA strand.

    • #33859
      Jennifer
      Participant

      DNA helicase unwinds the double helix by disrupting the hydrogen bonds of the base pairs of nucleotides. DNA gyrase relieves the tension from the unwinding of the double helix by cutting the strand, and reannealing it once the tension has been released.

    • #33905
      sdekivit
      Participant

      NOOOOOOO!!!!!! DNA gyrase = DNA topoisomerase II and produces negative supercoils

      –> DNA topoisomerase I relaxes these negative supercoils.

      DNA helicase pulls the DNA strands away from each other for transcription and is completely different from producing/relaxing supercoils

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