Biology Forum › Genetics › effects of point mutation on properties and function
- AuthorPosts
- May 1, 2006 at 7:36 am #4647
metalinfernoParticipantHi guys.. am new here.. need some help in biology as I just took up this subject this year….
Hmmm alright here it goes, with reference to the sickle cell anaemia, what are the effects of point mutation on properties and function of hemoglobin?
I am aware of the basic structural changes, such as the change in the shape of Hemoglobin from globular to sickle shaped. Is there anything more? and how does it change the function of hemoglobin, thanks!
,Nicholas
- May 1, 2006 at 10:59 am #47703kiekyonParticipant
the hemoglobin become less effective in transporting oxygen, smaller surface area
- May 1, 2006 at 2:57 pm #47706LilKimParticipant
Both the shape of the hemoglin changes (causing it to be "less effective in transporting oxygen…"- Kiekyon.) And.. also the shape of the RBC’s themselves change … further hindering their abliity to physically travel trhough small vessels and capillaries to deliver oxygen to tissue/cells.
- May 1, 2006 at 7:10 pm #47723MrMisteryParticipant
The shape of the RBC changes cause the newly formed haemoglobin(called HbS in literature) forms fibres, kinda pulling the walls of the cell
- AuthorPosts
You must be logged in to reply to this topic.
