Idiotype of antibodies ?

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    • #7323
      DMZ
      Participant

      how to answer this question please.

    • #70723
      blcr11
      Participant

      id·i·o·type(d–tp)
      n.
      A set of one or more antigenic determinants specific to the variable region of an immunoglobulin molecule.

      The American Heritage® Dictionary of the English Language, Fourth Edition copyright ©2000 by Houghton Mifflin Company. Updated in 2003. Published by Houghton Mifflin Company. All rights reserved.

      http://pathmicro.med.sc.edu/book/immunol-sta.htm

      I don’t know how good the above online text is, but the price is right (free). You can look up the basics of immunology there.

    • #72244
      david23
      Participant

      This what I can remember, I hope it helps. Hmm you know that antibody bind to antigens right. But did you know you can make antibodies attack antibodies too. idiotypes are antibodies’s varible regions (their own antigen recognition site), which are being attacked by other antibodies. So basically antibodies’ variable region are themselves being used as antigen sites. Maybe I can rephrase it a little.

    • #72273
      LilKim
      Participant
    • #72296
      david23
      Participant

      yeah i wrote too much. Just go with the definition of it being different variable regions.

    • #72800
      go6o
      Participant

      Guys? Do textbooks exist for you?

    • #72806
      david23
      Participant

      I did not look in the textbook for this one because I constantly use antibodies for blotting experiments, and idiotype was just something that came to me.

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