Lymphoid progenitor cells are only found in primary lymphoid organs, i.e. bone marrow, bursa Fabricius, and thymus, provided as repertoire. The ones found in lymph nodes and other secondary lymphoid organs are cells that already undergoing education, selection, maturation, and differentiation to be capable to recognize antigens.
The ones found in lymph nodes and other secondary lymphoid organs are cells that already undergoing education, selection, maturation, and differentiation to be capable to recognize antigens.
It is a dorsal diverticulum of bird’s cloaca, the origin of B-cells in addition to that ones produced in bone marrow in where B-cells undergo proliferation, education, and differentiation.
Then what is the difference between these cells and ‘null’ cells? They both seem to be an early stage of bone marrow cells
Null cell or killer cell (K cell) is a class of lymphocytes characterized by a lack of surface markers specific for either T or B lymphocytes. There is another type of lymphocytes called natural killer cell (NK cell), this type also lacks of that surface marker (CD3). K cell and NK cell has a difference on how they kill their target cells, K cell kills with a mechanism called ADCC (antibody-dependent cytotoxicity), whereas NK cells is antibody-independent.
The ones found in lymph nodes and other secondary lymphoid organs are cells that already undergoing education, selection, maturation, and differentiation to be capable to recognize antigens.
come out as a naive cells..I like “naive” words..
Naah, naive cells are the ones that have maturated in primary lymphoid organs but have not yet encountered antigen. The other word for this is "virgin" 😉
Just a suggestion for you, Vic. Because you learn Deutsch now, it would be much better if you notice the caps. Deutscher like everything in its place. That’s why they become a great nation. Deutschland ueber alles 🙂
