Nephron2 - Biology Forum

last updated by

MrMistery 19 years, 6 months ago

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- April 29, 2005 at 12:09 am #806
  JennJenn73_angel
  Participant
  Chloride ions, Cl-, follow actively transported Na+ ions from the nephron into the blood. would you not expect the Cl- concentration to decrease as fluids are extracted along the nephron? What causes the discrepancy?
- May 10, 2005 at 10:21 pm #22353
  star21
  Participant
  active transport, the carryer proteins dont allow this movement
- May 11, 2005 at 7:57 pm #22381
  MrMistery
  Participant
  Actually, most of the Na+ is not transported through a regular ion channel. It is used to transport glucose back into the blood thorugh a permease(simport transport). Some of the ions ar later absorbed through ion channels. In the permease it is simple: there is no place for the Cl- ion to bind. In the ion channel, if i remember correctly, you have negatively charged aminoacids at the surface that keep those ions out(electrostatic forces do not let them enter)
  Good question..
  Regards,
  Andrew
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