Iv’e been searching various online medical journals and search engines but haven’t come across one site that mentions NF-1’s impact on human homeostasis. All I know is that the NF-1 gene produces neurofibromin which acts as a tumor suppressor, and mutations in the gene lead to the formation of neurofibromas which take hold along the nerves of the skin and brain. I would appreciate some help or advice if possible but I know research regarding this disorder is relativley limited and ongoing. Given I am not as well seasoned as most of the users on this site but give me a break Im still in high school and got stuck with a relativley unexplored disorder. I understand that homeostasis is a complicated process invoving many bodily systems, but if neurofibromas are forming within the outer nervous system and under the skin, besides asthetic deformation, HOW does this inturn impact upon homestasis?