pepsins - Biology Forum

last updated by

Poison 18 years, 2 months ago

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- September 29, 2006 at 7:04 am #5844
  promage
  Participant
  I have learnt that pepsin digests proteins to polypeptides, and I have also learnt that enzymes which are biological catalysts are made of protein. So, my question is, wouldn’t pepsin digest itself since it is made of protein?
- September 29, 2006 at 7:25 am #55627
  asutoshsahu
  Participant
  Similarly I can ask u If our stomach get digested by its own digestive juice . answer is of course not.
  An enzyme has a certain conformation which targets a specific type of protein and so it can’ digest itself which is not the right confromation and it is not also energitically favourable.
- September 29, 2006 at 11:31 pm #55671
  promage
  Participant
  Oh, what about our hormones?
  My biology teacher told our class that trypsin from the pancreas is able to digest insulin when both of them are put together.
- September 30, 2006 at 10:26 pm #55715
  Poison
  Participant
  That question was asked previously. (By me 😆 )
  And the answer is,proteases DO digest themself. That’s why you continuously produce it.
  Here is the topic:
  viewtopic.php?t=1249
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