Biology Forum Cell Biology Please help!

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    • #15959
      Cloudrose
      Participant

      Where in the cell does glycolysis occur?
      In the presence of ample O2‘s what happens to pyruvate?
      Where in the cell is pyruvate broken down?

    • #109081
      canalon
      Participant

      I suggest you open your text book and look at the glycolysis chapter. There will be answers and maybe even light,

    • #109097
      billyfisher100
      Participant

      1) In the cytosol (the bit of the cytoplasm with no organelles).

      2) Pyruvate will enter the tricarboxylic acid cycle, be catabolised by pyruvate dehydrogenase into either Acetyl Coenzyme A or Ox.-Aloacetate. Then, the reduced nicotinamide adenine dinucleotide (NADH) and Succinate (C4O4) will enter an electron transport chain in oxidative phosphorylation to be oxidised, which is the most efficient way of releasing energy, unlike the glycolysis fermentation process.

      3) In the matrix of the mitochondrion.

      Hope this is better than looking in a textbook!

    • #109098
      billyfisher100
      Participant

      If you don’t mind me asking, just out of interest, is this A Level Biology you’re doing or is it part of a degree?

    • #109100
      JackBean
      Participant

      billyfisher100:
      1) what’s Ox.-Aloacetate?
      2) are you sure succinate is C4O4?
      3) succinate enters ETC?

    • #109116
      billyfisher100
      Participant

      1) Oxaloacetate is a compound (C4O5) in the tricarboxylic acid cycle, it is an isomer of Malate, after the action of Malate Dehydrogenase or Pyruvate Carboxylase, and is a compund which has been formed (sometimes oxaloacetate, sometimes acetyl, depending on the end compound that will be produced) after catabolism of pyruvate.
      2) Yes, it is only the carboxyl group, C4O4 succinic acid has 6 hydrogen atoms.
      3) Yes, oxidative phosphorylation, after a coupled reaction with Coenzyme Q to QH2 with the enzyme succinate dehydrogenase.

    • #109124
      JackBean
      Participant

      1) it’s difference between Ox.-Aloacetate and oxaloacetate
      2) no, succinate is not C4O4, you’re forgetting hydrogens 🙄
      3) succinate doesn’t enter the ETC. It just passes electrons to coenzyme Q, but otherwise is involved in TCA cycle, not in ETC

    • #109155
      billyfisher100
      Participant

      1. Sorry, I intended to type Oxaloacetate, not "Ox.-Aloacetate".
      2. Sorry, I mistyped that, obviously succinic acid is C4H6O4.
      3. Yes, succinate does pass electrons to Coenzyme Q (Q to QH2) but I thought you were referring to it entering "a stage" of oxidative phosphorylation, not primarily the electron transport chain.

    • #109237
      cbarlage
      Participant

      http://www.youtube.com/watch?v=p97BfO1c … ature=plcp
      Interesting way to explain cellular respiration
      this will probably help you out

    • #109239
      JackBean
      Participant

      not so sure about that

    • #109312
      billyfisher100
      Participant

      Neither am I, I agree with JackBean on that one…

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