is their any other interactions involve in DNA stability other than hydrogen and covalent bonds,, i have to do work on assignment "role of supramolecular interaction in DNA self assembly" plz help me.. i m very much confused i did not find any ionic, hydrophobic or vanderwal interactions involved in DNA assembly, is hydrogen bonding and phosphodiester are the only two bondings involve in DNA stability?
nope. actually H bonding don’t really contribute much to the thermodynamic stability of the DNA molecule. the bulk of the stability is accomplished through base stacking http://en.wikipedia.org/wiki/Pi_stackin … in_biology
From what I know it’s not actually 100% what sort of interactions contribute to the phenomenon known as pi stacking, but it is definitely THE major contributor to the thermodynamic stability of the DNA double helix
thanks , this information is really new for me, i have studied that that DNA is natively present in water, and there is some hydrophobic interactions also involved in stability, do you have any idea about it?
thanks , this information is really new for me, i have studied that that DNA is natively present in water, and there is some hydrophobic interactions also involved in stability, do you have any idea about it?
