Biology Forum › Molecular Biology › RNA degradation with alkali?
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- March 30, 2006 at 7:55 am #4242bbs_rParticipant
According to:
quote :How does the akali destroys mRNA in the hybrid? Does it means "the bonding of nucleotides in mRNA degrades naturally in a high pH"?
Or I had misunderstood its meaning?
Thank you very much!
- March 30, 2006 at 8:31 pm #44683XgeneParticipant
mRNA has ribose sugar in its nucleotides, which is susceptable for alkali degradation. where as in the DNA deoxy ribose is present in its nucleotides which will resist alkali degradation.
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