synthetic enzyme substrates

[felicity_wishes]

Anyone know where I can get detailed information about synthetic substrates from? Something along the lines of their uses, purposes, history etc?

Any journals or websites would be really helpful.

Many thanks.

[weesper]

Give me an example and I’ll try and help you

[felicity_wishes]

Well, anything from as broad as what they are and their purposes, to examples such as chromogenic or fluorogenic substrates for hydrolases/glycosidases.

Thank you.

[weesper]

Oh so you want to everything?

Go to http://www.syntheticsubstrates.com

Seriously if you’re asking such as broad question I can only give you broad replies. Give me one concrete example.

[felicity_wishes]

Seriously – I need like a general overview. No details about their synthesis or one particular substrate or type of substrate. Just a general overview.

Perhaps something about their applications, and future prospects? Their use in clinical diagnosis?

PS. I don’t know if you know, but that link doesn’t work. Thanks for your help anyway.

[oppox]

yea I think he knew 😉 . I think the best u can do is search it, search googles and in journals etc. I dont think u will find an overview in one place since its alot of substrates for alot of different proteins.

[weesper]

Yes next time I’ll also put a link up to http://www.canyouhandleajoke.com to make sure the message gets across. take care good luck

[felicity_wishes]

Thank you oppox for your reply 🙂 I have tried google and journals, but can’t really find much about where it all started and who came up with the idea and why – but I shall keep looking anyway! I need to write an introduction on "synthetic enzyme substrates and their applications". More specifically, I will need to focus on chromogenic substrates for glycosidases. Thanks again – I’ll keep looking 🙂

Weesper – lol…I can handle a joke – I just didn’t know it was one 🙂
So perhaps something like http://www.isitajoke?.com would be more uselful for me. I can click on the FAQ page and read up the "50 ways of determining when someone is being funny over the internet" section…
thanks anyway! 🙂

[canalon]

As far as I remember it started with Monod and the use of IPTG/Xgal to study the Beta-galactosidase activity. But it was long ago and I do not have the book anymore 🙁

[felicity_wishes]

Thank you for the information – it’s helpful. I’ll try searching that as well 🙂

[Author]

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