Biology Forum Evolution Theories – Origin of Life

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    • #10139
      chilipanda
      Participant

      Hey guys,

      I’m writing a paper on the origin of life, and I need some suggestions about which theories to write about. Obviously there are tons of them, so any suggestions, information, or references you guys can give me would be great.

    • #86005
      alextemplet
      Participant

      Most biologists believe RNA was one of the first biochemical molecules to develop, and experiments have shown that under the right conditions it can perform the functions of itself as well as those of DNA and proteins. In fact there is an entire hypothesis called the "RNA world" that has been developed around these concepts; look it up on google or wikipedia and you’ll find plenty of info.

      At my university, a group of students recently conducted experiments in which RNA was found to spontaneously isolate itself inside protective spheres of phospholipids. I’ll have to see if I can get a copy of the research paper; they think this could lead to explaining the formation of the first cells.

    • #86014
      MrMistery
      Participant

      basically when you’re writing something like this, you wanna look up what the mainstream belief is and write about that. You may also include a chapter on "alternative hypothesis" but it should be best to stick with the mainstream one

    • #86087
      YashArya
      Participant

      Guyz, has anyone here heard of "Carin Smith’s" theory on the Origin of life?
      It tries to prove that the initial replicators was not RNA or some other molecule, but actually "clay replicator".

      Check this website dedicated to the theory.
      [http://originoflife.net/crystals/index.html]

      I haven’t read Carin Smiths book but I’ve been reading Richard Dawkins – "The Blind watchmaker" (currently in Ch:8)

      I was quite impressed by the theory, it is logical. However I don’t know if there is much evidence for it.

    • #86091
      canalon
      Participant

      It is Cairn-Smith, but if I remember some people that know their chemistry better than I do have been able to point multiple flaw in that otherwise interesting and elegant theory.

    • #86096
      chilipanda
      Participant

      Carins-smith has two books about the clay theory, "seven clues to the origin of life", and "genetic takeover" i believe. seven clues is very well and easy written, in a sherlock holmes style that is somewhat enjoyable to read. genetic takeover is much more in depth, but has been given very positive reviews. i havent had time to read either myself but i plan on finishing seven clues when i finish my paper.

    • #89468
      Alberts
      Participant

      I think you’d better write about "protein-first and nucleic acid-first" paradox. The research articles of Joyce, Orgel, Eigen and Dyson can be an useful reference for you. Best wishes.

    • #89513
      mcar
      Participant

      I remember some; Biblical, biogenesis, spontaneous, physico-chemical and cosmozoic theories.

      quote :

      alextemplet wrote: At my university, a group of students recently conducted experiments in which RNA was found to spontaneously isolate itself inside protective spheres of phospholipids. I’ll have to see if I can get a copy of the research paper; they think this could lead to explaining the formation of the first cells.

      I have thought if they’re viruses but since you have said "phospholipids" my thought lead me to a true cell. It just reminded me of some questions like what made the certain elements to react with one another and form such first biomolecules of life or perhaps their interactions were spontaneous indeed.

    • #89537
      MrMistery
      Participant

      by the way alex, i hope your peers published their results, cause if not jack szostack beat them to it
      http://www.nature.com/nature/journal/v4 … 07018.html

    • #89618
      futurezoologist
      Participant

      I am assuming you mean how it started and the above posts pretty much sum it up but if you mean where it started youve got:

      panspermia hypothesis: life came from another planet on meteorite etc.

      Bible: you know

      or the mainstream – it originated on earth because the early earths atmoshere had no oxygen=no oxydisation=organic compunds are able to exist(e.g. Nucleic acids, proteins, carbs etc) and were created by energy discharges like lightning or using the heat from volcanism.

      Google and you will find loads on any of these.

      ps. sorry for any typos… im running late for an appointment.

    • #101990
      believer
      Participant

      Everyone that has ever commented on the origins of life are reduced to their opinions, even the great Richard Dawkins is left to speculation. The last time I saw Dawkins he said no one knew how the first lifeform started and speculated that it could have come from Aliens. The chances of DNA occuring in nature by accident were put at "No mathematical possibility" That’s 0 for you that have trouble with numbers, The problem with those of us who dont believe in evolution is all the steps it would take to get to advanced life without the species dieing out.All the vital organs that each species have that without any of them "no life". What happened on Earth even 10,000 years ago is really a mystery because there are no written records of those events, of course evolutionists will disregard any other explanation of life as foolish. The Bible says that the proof of God is in Nature, look at the beauty and complexity and then reason.

    • #102496
      madriley
      Participant

      You should read the first chapter of Nick Lane’s new book "Life Ascending." He discusses the reasons why the "primordial soup" idea is not feasible (mostly because there is very little evidence and there are problems with thermodynamics) and discusses more recent research into life evolving in hydrothermal vents.

    • #102620
      BDDVM
      Participant

      The thing that many seem to forget about the origens of life on earth is that it happened without any competition. It’s not like these molecular oddities had to get started on the current earth. They just had to be able to get the replication/variation/selection cycle started.
      DNA doesn’t have to spontaneously generate. RNA seems to be able to start the process of evolution all by itself. Obviously not well by modern standards, but when there’s no competition, no enzymes (RNAases) nothing to get in the way, it’s not hard to imagine that those early RNAs mutated to assemble protiens to protect them, DNA to more stabily store RNA templates and cells to concentrate nutrients.
      If you break it down into baby steps it becomes almost inevitable that life happened.

    • #102801
      lifefrommembranes
      Participant

      I have a new theory for the Origin of Life on the earth. Life has originated from primordial membranes that have formed from hydrocarbon chains in the earth’s crust about 3.7 billion years ago. These membranes developed electrical potentials resulting in the evolution of consciousness. The erosion of the hydrocarbons by the membrane potentials led to the development of various other organic molecules.

      I have propounded a hypothesis with an adequte scientific ground. I have written a book titled "The Role of Cell Membrane in the Origin of Life and in Cell Biology". If you are interested you may discuss it in full detail with me.
      Dr Krishnagopal

    • #102803
      BDDVM
      Participant

      The processes you describe sound like excellent candidates for recreation in the lab. Do you have any simulations in the works? Repeatable evidence is the difference between "science" and "making stuff up".

    • #102846
      gabielk1
      Participant

      I thought When Earth was a molten surface. It was Bombarded with space objects that carried the first round of life-bearing substance and imbued the planet with its own sense of identity. Before the earth experiment began and the turning of the hardened planet surface into habitable by electrically shocking the core with a laser, and spray an oxygen shell around atmosphere with plasma ballon inflation. Then people arrived… How come there is no consensus??

    • #102868
      BDDVM
      Participant

      Pease tell me you are kidding.

    • #103972
      Jonl1408
      Participant

      Have any of you thought about the fact that the model of Evolution, is totally destroyed by the Second Law of Thermodynamics, which says that in all energy exchanges, if no energy enters or leaves the system, the potential energy of the state will always be less than that of the initial state.

    • #103973
      BDDVM
      Participant

      OK I’m going to try to explain the second law of thermodynamics without resorting to math.
      The basic idea is that things that are ordered will tend to become disordered. Think of a carefully stacked pyramid of cannon balls. Anything you do to the cannon balls will tend to result in thier no longer being piled up neatly in a pyramid. In fact no matter how much you randomly fiddle with them the chances of them ever being neatly piled in a pyramid again are infinitessimal.
      Notice I said randomly. If, however, you decide you want them to be in a neat pyramidal pile and start restacking them you do not violate the second law (obviously it’s possible I’ve seen it done) when you succeed in stacking them. If you only fixate on the pile of cannon balls it appears that the order has increased. The universe, and the laws of thermodynamics,take a more wholistic view. Into the entropy equation go many other things besides the cannon balls small increase in order. There is the energy used by the person doing the stacking (Millions? of molecules of chemicals converted to more random forms, Lots of just plain heat given off by doing Work that cause the molecules in the area to move faster, get farther appart and be less ordered.)
      Things can become more ordered locally if the process also makes even more disorder happen elsewhere. Life and evolution are increadably good at this.

    • #103989
      Jonl1408
      Participant

      You said that it appears as if the pyramid, has become more complex, as in an optical illusion, because the really haven’t become more complex, just reorganized, right?
      Does that mean that you are saying that evolution just reorganized the cells in animals, so they haven’t evolved, they were just reorganized?

    • #103995
      BDDVM
      Participant

      My explanation was about the 2nd law, not evolution. I said the stacked balls had more order, not complexity. They are not synonymous. You need to understand these concepts without the bias of trying to prove or disprove anything. If you feel you must disprove evolution all you have do do is come up with another theory that explains how life works and is consistent with all the evidence collected by humanity.

    • #103998
      Jonl1408
      Participant

      Very true, and that other theory, is called Creation.

    • #104002
      BDDVM
      Participant

      Many would argue that creationism isn’t even a theory. I think this is wrong. Creationism is a theory and it’s easily stated. God did it. Being scientists we like to check the details though. How, where, why and when did god do it? To be a good beleivable theory you must have good (prefferably logical and obvious) aswers to these questions . Let me also add that evidence can’t be strictly heresay. Because Moses said so doesn’t cut it.
      You must also explain my favorite problem with creationism. Why is your intelligent designer so bad at designing? A couple quick examples, The lower back (lumbar vertibrae) , Why do the paths of air being breathed and food being swallowed cross each other? (serious chocking hazard). Why give the gift of flight to birds and not us? Why give a much more efficient repiratory system to birds and not us? Maybe God likes birds better. Ask any doctor for further examples of poor design.
      Creationism is a theory, just a bad one that was abandonned in the 19th century for good reasons.
      Believe whatever you want but if you choose to believe something stupid I reserve the right to dispute you and laugh at you if it’s really dumb.

    • #104003
      Jonl1408
      Participant

      Also although you may think that Creation has been abandoned, there are thousands of people, that would disgree with you there.
      I have said this many times, and I will say it again, if you go back to the very beginning of either viewpoint, you come up with an eternal Intelligent Creator (God) or eternal matter. Evolution takes more faith to beieve in, than Creation.
      http://www.great-quotes.com/quote/1117193
      Also why is it that most people on this website, answer my comments with insults. Sure, I can see that none of you like what I am saying, but throwing insults rather than providing evidence, makes you sound very unintelligent, and not professional at all.

    • #104004
      BDDVM
      Participant

      I thought we were discussing science not faith. Obviously if you are using faith you can believe anything you want and I can’t argue with faith. Faith does have some spotty history though. Good ideas according to faith, Burning people alive, crashing airliners into office buildings, killing healthcare providers etc. Then there’s the problem of faith in who? You mentioned thousands of people who believe in creation. Can’t argue with that statement but there are hundreds of millions who believe that the creation theory includes the world sitting on the back of a really big turtle. Does that sound more of less silly than flammable shrubbery telling you what to do.
      You also haven’t answered my questions about why your intelligent designer doesn’t seem able to design very well. Why creat all those people who believe all those untrue religeons?
      As for insulting you, don’t feel bad, Aristotle, one of the great minds of western civilisation, was wrong about everything. It took hundreds of years of science to undo the weird stuff he made up.
      Also in science we try not to take things personally.

    • #104005
      Jonl1408
      Participant

      First of all, there is evidence for Creation, as I have shown in many posts on this website.
      Second, about why God created people, who do not worship him, God doesn’t want mindless zombies, he wants people to accept him because they feel grateful to him. Think about it, if you were able to create beings capable of their own thoughts, wouldn’t you rather create them, rather than some machine that tells you that you are awesome every morning?
      As to the insults I am not merely complaining, I take no offense at your insults, but I like to think that I am conversing with intelligent people, who back up their claims with evidence, rather than people who just call names.

    • #104013
      BDDVM
      Participant

      Still no answer for why the design is so bad and seems to be overly dependent on designs carried forward from earlier ancestral forms. In evolution it’s called evolutionary baggage and it’s just what you would expect.

    • #104016
      Jonl1408
      Participant

      Give some examples of bad designs please.

    • #104032
      BDDVM
      Participant

      The chiropractic industry is based on the lower back pain that humans are so prone to.
      Only an idiot would have the path of air into the lungs cross the path of food and water into the stomache. Serious choking hazard.
      On the subject of breathing our lungs breath in and out through the same path, this mixes new air with old air which is very inefficient. Birds have a better system that uses a series of air sacs to push air through the lung in only one direction.
      Heck if I was designing humans I’d make them able to fly and photosynthesize and rationally control our population.
      I’d also suggest that sex should be more satisfying with long term committed partners than first time flings and adultery.
      Why viruses?
      Why birth defects?
      Why cancer?

    • #104048
      Jonl1408
      Participant

      There may be reasons for that setup, as there were for the appendix, which man thought was useless, until it was discovered that it had many purposes. Also there would be many problems, with man being that way, and what do you mean by rationally control our population?
      As to your questions, let it suffice to say that if man lived his life the way that God intended him to, we would have none of those problems.

    • #104050
      BDDVM
      Participant

      When you say "there may be reasons" in science you are then expected to say what those reasons are.
      I’m curious, I know what the appendix (Cecum) does in other species. Slow fermentation of fiber.
      What are those great things that it does in humans that would outweigh the intense pain and death associated with it? Why can’t God make it work for us without the apendicitis?
      In science attempting to avoid answering questions makes people assume you don’t know what you are talking about. Better to say "interesting question, I don’t know". That way people will at least think you gave it some thought.
      As you are new to science I will give an example.
      God created everything therefore God created cancer. He gave us cancer to make us appreciate life more. Not obviously very convincing to those who get cancer but it at least follows the right form and is logical.

    • #104054
      JackBean
      Participant

      just look on our eyes

    • #104056
      BDDVM
      Participant

      we are trying to have a conversation for grownups if you don’t mind.

    • #104059
      JackBean
      Participant

      if it was to me, I was suggesting another example of bad design

    • #104061
      angel92
      Participant

      Hypercycles, as an overarching organization of autocatalytic sets, have been proposed as a model for the origin of life (Eigen and Schuster 1977) and are explained at Principia Cybernetica Web. However, complex hypercycles only exist as computer simulations. More than thirty years after the introduction of the hypothesis, there is no experimental evidence whatsoever for complex, possibly prebiotic hypercycles. This makes them still nothing more than mere speculation and, while the hypothesis has been a recurring theme in the scientific literature about the origin of life, it is not frequently mentioned anymore in recent publications in the field.
      So far only one, very simple, hypercycle has been generated more than 10 years ago in the laboratory with two self-replicating peptides by the group of Ghadiri (Lee et al. 1997). However, these authors posted a correction (Lee et al. 1998) where they state: “Although the kinetic data suggest the intermediary of higher-order species in the autocatalytic processes, the present system should not be referred to as an example of a minimal hypercycle in the absence of direct experimental evidence for the auto-catalytic cross-coupling between replicators.”
      There is a single report on a naturally occurring hypercycle (Eigen et al. 1991). But this example, relating to the infection cycle of an RNA bacteriophage, obviously is not prebiotic – the cycle evolved on the complexity of living beings as template.

    • #104065
      BDDVM
      Participant

      You might want to use less jargon in this forum because I for one have no idea what you are talking about or why.

    • #104071
      Jonl1408
      Participant

      The appendix helps your immune system. You want me to list the reasons, we haven’t discovered any yet, just like we had no reasons for the appendix, until people understood what it was for. The Bible gives a guideline, on how to live a healthy life, but man completely ignores it, because it mentions cutting out foods that we have grown up loving. There are some groups of people today, who have grown up eating the way that the Bible says to, and those people, are some of the healthiest people on the planet. They do not get cancer or other diseases. The Hallelujah diet, is a diet that focuses on following God’s food laws in the Bible. Cancer patients, given months or less to live, decided to try the diet, (they had nothing to lose) and not only did the live, but they were cured of the cancer, in a relatively short time period. I am not just speaking of a few people either, there have been a few hundred cancer patients cured, and not just cancer patients but tons of people with other diseases too. http://www.hacres.com/library/testimonies/search
      Also when did I not answer your question?

    • #104075
      BDDVM
      Participant

      Wouldn’t that be nice if it were true. You see I don’t trust your sources. Lying to forward your biases is just too easy. In science we require evidence that is not tainted by bias. Now when I say lying I am not necessarily saying that intentional untruths are being said. It is at least as likely that the underlying bias has made your sources actually believe what they are saying. Self deception is the easiest because we automatically thrust the source. Science (at least good science) assumes bias exists and goes to great lengths to expose it and compensate for it. Just wanting to believe is a huge bias and requires extreme controls to get to the facts through the fog of bias.
      Scientists don’t do multiple controls and double blind studies because we like them. We do them because we don’t trust ourselves any more than we trust creationists.
      Murphy is a scientist, whatever can be biased is biased.

    • #104418
      scottie
      Participant

      I have only just joined this forum and have been rather interested in this thread.
      In particular the debate between Jonl1408 and BDDVM.

      Jonl1408
      You clearly have a confidence in your bible and trust it considerably. May I suggest that when you debate the bible in a science forum you be prepared to debate science not faith.
      Now you clearly believe that the God of the bible designed man (indeed everything else) as the bible states. However the bible also states that something else is at play here in that man’s condition has been tampered with, you have only to refer to Hebrews 2:14 to show that death and suffering was not part of the original design.

      Now if someone believes the bible account is just a myth, at least you can point to the account as being consistent within itself and it explains the current situation of man.
      What I am suggesting is that if you get to know your bible better you would therefore be better prepared to debate with anyone who does not share your belief.

      BDVM
      I can see you are an educated person and adhere to evolutionary theory, although I am uncertain as to what branch of evolutionary theory you subscribe.
      However when you state that
      “Only an idiot would have the path of air into the lungs cross the path of food and water into the stomache.” I feel you are being more than a little arrogant.

      May I suggest you check out the actual design of the human respiratory system and it’s control, perhaps here
      http://en.wikibooks.org/wiki/Human_Phys … ory_system and inform how you would modify the system away from idiocy.

      Please keep in mind that vague statements about the superior system of the birds is just simple rhetoric unless design detail accompanies your comments.

    • #104419
      BDDVM
      Participant

      Some requested details which I’m afraid will be somewhat longwinded for this forum.
      To improve the human respiratory system ( without a major overhaul) simply move the esophagus in front of (anterior to) the trachea so the air pathway and the food/water pathway don’t cross each other.
      Avian respiratory anatomy and physiology is kind of complicated but I’ll give it a shot. The windpipe opens at the base of the tongue where debris isn’t trapped easily like the back of our pharynx. A system of air sacs then direct air through the lung in only one direction which keeps incoming air from mixing with outgoing air thus greatly increasing oxygen transfer efficiency. It’s actually a very cool system. If you watch a bird inhale and then exhale the air you see coming out was not the air that was just inhaled, it’s the air that was inhaled the time before. If a bird was smoking the smoke would come out a breath later than expected. If we had this level of oxygen transfer efficiency we could likely run 3 minute miles. I’m just saying that for an intelligent designer the designs look like they were put together without much intelligence.

    • #104431
      canalon
      Participant
      quote scottie:

      Please keep in mind that vague statements about the superior system of the birds is just simple rhetoric unless design detail accompanies your comments.

      And why would that be? There are countless design that would work better than what we have. Anything that you can imagine where respiratory and food ingestion system are separate. teh point is if it evolved it somehow makes sense for the 2 system to have ended up that way, however absurd and unnecessarily complicated and failure prone it is, but if it had been designed from scratch with even a modicum of intelligence separation of the system would be part of the design requirement.
      In fact as with many things there is no need for our body to have all those design quirks that are proving to be annoying (design of our spine, absence of protection of the sensitive abdominal area, excretion and reproduction system sharing conduits…) unless you consider that they evolved from preexisting structures that constrained them so much that a better design was not possible. The problem with (un)intelligent design hypothesis is that it completely fails to explain why if we have been designed, those major problems have not been taken in consideration from the start.

    • #104452
      scottie
      Participant

      BDVM

      Thanks very much for your response. It is certainly educational and appreciated.
      I am also glad you have modified the language of your critique in the comparison between the bird/ human respiratory and digestive systems.

      I understand the nub of your argument but feel it is a view that is rather simplistic and I don’t mean this in any derogative sense.

      In my question to you I deliberately referred to control of the systems, those that which are housed in different parts of the brain. You have simply sought to focus on the mechanics of the systems.

      Although there are common functionalities between the two systems the fact is that the human system is far more elaborate and indeed versatile. We have only to examine the taste and vocal abilities of the two to appreciate that one is more sophisticated than the other.

      The epiglottis is the flap of cartilage located at the opening to the larynx.
      During swallowing, the larynx closes to prevent swallowed material from entering the lungs, the larynx is also pulled upwards to assist this process. Stimulation of the larynx by ingested matter produces a strong cough reflex to protect the lungs.
      You rightly refer to choking that occurs when the epiglottis fails to cover the trachea, and food becomes lodged in our windpipe.

      The closing of the larynx during swallowing indicates anticipation does it not?

      I would argue that this is not a matter of faulty design but one of faulty maintenance.

      The two systems operate in two different environments and have different purposes while having some common functions.

      I don’t see why should one system be considered the product of idiot design and the other not.

      Now canalon raises a good question and I will respond in my next post shortly.

    • #104454
      BDDVM
      Participant

      I don’t actually believe an idiot designed anything. Evolution did it. The fact that our bodies seem bodgered together is just what you would expect from such a simple and often imprecise process.
      Those who advocate the scientific theory of Creationism or Intelligent design must explain why these problems exist (every single one of them). Furthermore their explainations must be consistent with their definition of the creator/ designer.
      No fair claiming god created evolution while saying evolution didn’t happen.
      Incidentally, part of the nerve supply to the larynx , the recurrent laryngeal nerve, is another example of Rube Goldburg type design.
      The nerve starts as a cranial nerve , XI ? I don’t recall exactly. Anyway it starts at he base of the skull and heads south, goes right past the larynx, loops around the base of the heart and ends up at he larnyx. This path makes it one of the longest periferal nerves in the body. Unfortunately periferal nerves have to get all their nutrition and metabolites to the ends of their axons through those axons. This becomes increasingly difficult as those axons get longer. In dogs at least this often leads to the nerve becoming damaged with age to the point that about once a month I see an old dog that can’t open the larynx to inhale. A 50cm nerve that wears out where a much more healthy 10cm nerve would work fine. Not intelligent, evolutionary baggage.

    • #104455
      scottie
      Participant

      canalon

      quote :

      “teh point is if it evolved it somehow makes sense for the 2 system to have ended up that way, however absurd and unnecessarily complicated and failure prone it is, but if it had been designed from scratch with even a modicum of intelligence separation of the system would be part of the design requirement.”

      When you used the term evolved I assume (correct me if I am wrong) you refer to random variation followed by natural selection i.e. (survival, mate-finding, reproduction)

      Now for the moment lets stick with the respiratory/digestive system mentioned as evidence of as you put it (un)intelligent design.

      Did you know (perhaps you do) that our mouths can only distinguish 5 different tastes, sweet, salt, sour, bitter and umami (or savouriness).

      But you also know that when we enjoy a really good meal we are definitely not limited to those 5 tastes.

      So what’s going on?

      The other flavours (as distinct from the term taste) is detected by flavour molecules stimulating our olfactory glands in the nose. (part of the respiratory system)

      Try the following experiment to see this in action:
      Take a piece of any strong flavoured food (say cheese or garlic), hold your nose and put it on your tongue and rub it against the roof of your mouth.

      What can you detect? probably just salt or one of the other 4 taste sensations.
      Now let your nose go and breath in as you taste (part of the digestive system) the morsel of food, suddenly the flavours erupt in your mouth and nose. 

      Everything we smell in life comes from these 5 atoms.
      carbon
      nitrogen
      hydrogen
      oxygen
      sulphur

      These 5 atoms form into different molecules and molecules vibrate at different frequencies and a spectroscope can analyse the vibrations and determine what the molecule is.

      We smell molecular vibrations( according to theory), now the fly in the ointment is that if you looked up the nose of the person next to you what you would not see is a spectroscope. 🙂

      Birds have an acute sense of taste. Taste is used to help avoid harmful foods. Sensory receptors inside the bird’s mouth detect sweet, salt, sour (acid), and bitter tastes. Sensitivity to each of these tastes differs from species to species.
      http://www.seaworld.org/animal-info/inf … senses.htm

      The sense of taste is part of their survival package.

      Do birds enjoy the full flavour as humans do? The answer is no. One major reason is that the sense of taste and smell do not combine as they do in humans. (separate systems as we are informed)

      The point I make is this
      This highly developed combination of senses in Humans is clearly not a requirement for survival, findng a mate or reproduction ie Natural Selection.

      So the obvious question is why do we posses this quality and not birds.The only good reason I can come up with is pleasure.

      Now where does pleasure play a part in natural selection. I don’t know, can anyone educate me please.

      To combine the two systems far from being an example of bad design is a excellent example of good design, if only for the reason it adds pleasure to what is otherwise an essential requirement.

      I could take up your other points (design of our spine, absence of protection of the sensitive abdominal area, excretion and reproduction system sharing conduits…) but perhaps we could move on to them later

    • #104456
      scottie
      Participant

      BDDVM
      I know you don’t believe an idiot designed anything.

      But before we go any further I would like to make one thing clear. I am neither a creationist nor an advocate of the ID community.

      I have made a study of the various denominations of evolutionary thinking, and there are several, and all coming up with separate ideas.

      I have similarly made a study of the bible though not the Qu’ran and the religious churches of Christendom and Islam again come up with different ideas, each one claiming they are right.

      Science is my interest.
      Science in my opinion should not be tied to any philosophy.

      Getting past my bedtime now so must conclude for the time being.

      Now I don’t get hung up on terminology. When I see design I see it for what it is –Design. I don’t need to prefix it with adjectives such as “Intelligent” as the ID community does or “Apparent” as Richard Dawkins does.

      How did this design come about? Well I don’t see this has been answered by science.
      We haven’t even been able to explain what life is so how can science know how it came about. If it came about by supernatural means then science will never be able to answer it.

      Science however can explain how it could not have come about.

      So when you claim that that it is the result of evolutionary process then I need to pin you down to explain which evolutionary theory you are subscribing to, as there are many.

      With respect you have not answered that yet.

      Could you possibly answer that question please.

    • #104457
      BDDVM
      Participant

      Pleasure is evolutions way of rienforcing decisions that make you more likely to live and reproduce. Generally, apples taste good and feces, decayed meat etc taste (and smell) bad. Incidentally there are exceptions as one would expect in a process that takes at least one generation to eliminate deliterious variations. Some people can’t resist feces and other not so healthy dietary choices.
      Some of these preferences are learned, some are inate and adjusted by learning and some are inate.
      I have been accused of offering simplistic answers to these questions.
      In science, simple answers are prefered.

    • #104458
      BDDVM
      Participant

      Scotty I am sorry, I don’t know what you mean by denominations of evolutionary thinking. Could you name a few. Also I’m not sure of your point about the sense of smell/taste in birds. Birds in general have poor sense of both taste and smell. Flight makes smells hard to track and places a premium on eyesight. Food is generally identified visually and is very inflexible. Once a bird starts eating sunflower seeds it’s difficult to get them to even try a food with a different appearence. Even ground sunflower seeds.

    • #104459
      canalon
      Participant
      quote scottie:

      When you used the term evolved I assume (correct me if I am wrong) you refer to random variation followed by natural selection i.e. (survival, mate-finding, reproduction)

      Now for the moment lets stick with the respiratory/digestive system mentioned as evidence of as you put it (un)intelligent design.

      Did you know (perhaps you do) that our mouths can only distinguish 5 different tastes, sweet, salt, sour, bitter and umami (or savouriness). [… snip for brevity…]
      To combine the two systems far from being an example of bad design is a excellent example of good design, if only for the reason it adds pleasure to what is otherwise an essential requirement.

      I could take up your other points (design of our spine, absence of protection of the sensitive abdominal area, excretion and reproduction system sharing conduits…) but perhaps we could move on to them later

      My answer is simple: WRONG.
      The design is essentially bad and over complicated. The fact that there is a silver lining to that does not make it any better. If the fact that Windows Millenium Edition was so buggy that it required almost monthly reinstall limited the usual accumulation of crap in the registry, it did not make it a better OS than windows 98. 😆
      There are countless way to make the 2 systems communicate and do that more safely if you can design it from scratch. Or to have the olfactive system actually located in the mouth (like snakes) or to make the tongue more sensitive. This is a clunky design that was born of randomness and necessity while nature’s tinkering where constrained by the preexisting.
      And in fact no amount of rationalisation is convincing: Bad design is bad design whatever later improvment come afterwards. Human have the ribcage of tetrapods, in spite of being bipedals; our larynx and excretion system should not have been connected the way they are if they had been designed. But there never was design or intent, just random tinkering and selection, and a bit of serendipity. Look at the thumb of the panda (and read S.J. Gould’s book by the same name, and most of his other book, they are worth it) and many other examples in nature and all we can see is Chance and necessity (Thank you J. Monod).

    • #104464
      LeoPol
      Participant

      How have emerged and have become sensible ones membrane-ids, which for many billions of years ago, have built a peptide-nucleic super-technology – is an open question. But how do these membranoidy appeared on Earth – we can explore …
      http://translate.google.com/translate?h … .agro.name
      And the dream! http://spacenoology.agro.name/?page_id=4904

    • #104470
      BDDVM
      Participant

      Leopol, I don’t know if your post was nonsense before it was translated but it’s certainly nonsense now.

    • #104480
      scottie
      Participant

      BDDVM

      Denominations
      Let me try and explain.
      (1) There is the modern Standard Theory of Evolution which essentially states .. well
      here is a good description from:-
      http://www.fossilmuseum.net/Evolution.htm

      Evolution and the Tree of Life
      The modern theory of evolution is based on two primary tenets:
      All living things are related to one another to varying degrees through common decent (share common ancestors), have developed from other species, and all life forms have a single common ancestor.
      The origin of a new species results from random heritable genetic mutations (changes), some of which are more likely to spread and persist in a gene pool than others. Mutations that result in an advantage to survive and reproduce are more likely to be retained and propagated than mutations that do not result in a survival to reproduce advantage.
      The great Tree of Life is real. It is a phylogenetic tree representing the unique ancestral history of each and every creature. Darwin believed that all creatures on Earth might have originated from a single common ancestor so that each species through geological history fit somewhere in an overarching metaphorical tree;

      (2) From Wikipedia ( I am always cautious about using wiki but in this case they have it about right.)
      Punctuated equilibrium is a theory in evolutionary biology which proposes that most sexually reproducing species will experience little net evolutionary change for most of their geological history, remaining in an extended state called stasis. Punctuated equilibrium also proposes that stasis is broken up by rare and rapid events of branching speciation called cladogenesis. Cladogenesis is the process by which species split into two distinct species, rather than one species gradually transforming into another.
      Punctuated equilibrium is commonly contrasted against the theory of phyletic gradualism, which states that evolution generally occurs uniformly and by the steady and gradual transformation of whole lineages (anagenesis). In this view, evolution is seen as generally smooth and continuous.
      In 1972, paleontologists Niles Eldredge and Stephen Jay Gould published a landmark paper developing this theory and called it punctuated equilibria.[2] Their paper built upon Ernst Mayr’s theory of geographic speciation,[3] I. Michael Lerner’s theories of developmental and genetic homeostasis,[4] as well as their own empirical research.[5][6] Eldredge and Gould proposed that the degree of gradualism commonly attributed to Charles Darwin is virtually nonexistent in the fossil record, and that stasis dominates the history of most fossil species.
      http://en.wikipedia.org/wiki/Punctuated_equilibrium

      Two opposing views on one of the fundamental pillars of of Darwinian theory.

      Another fundamental pillar of Darwinian theory is the notion of Common decent. (Tree of life) as explained above.
      (3) Carl Woese and others like Craig Venter disagree fundamentally with this concept.
      He describes this as “the doctrine of common decent” and is wrong. There is no tree of life, if any such analogy is to be used then a bush or forest would be more appropriate.

      Again on one of the fundamental pillars of the standard theory there is disagreement.

      So here briefly are three different theories but there are more.

      I could relate Jim Shipiro’s Natural Genetic Engineering view which he states is the third way between Creationism and Darwinism.
      Or Simon Conway Morris who argues against Gould and Darwin in that evolution far from being quirky and unpredictable is essentially front loaded in that the evolutionary routes are many but the destinations are few.

      Or Lynn Margolis... ….I think I had better leave it there in case everyone starts dozing off. 🙂

      The reason I use the term denominations is because each theory has it’s own doctrinal fundamentals and the fact that the adherents of one disagree with another, often with a vitriol that smacks of a sort of religious fervour, paints a picture for me.

      Does evolution happen? It most certainly does and we have the evidence all around us.
      What does that evidence show, well quite simply that all this evolution occurs within species.

      Does it produce new species. Well I am waiting for anyone to demonstrate that with evidence and not speculation.

      If anyone believes that speciation occurs through evolution by whatever formal theory, I have no problem with that.

      It becomes a problem when that belief system is presented a fact.

      I hope this clears up some of my points.

      btw my comment about birds having a keen sense of taste is actually a quote from the Orlando’s sea world website, I gave the link in my response to canolan, here it is again
      http://www.seaworld.org/animal-info/inf … senses.htm
      Scroll down to Taste.

      Thanks

    • #104484
      LeoPol
      Participant
      quote BDDVM:

      Leopol, I don’t know if your post was nonsense before it was translated but it’s certainly nonsense now.

      But other forum participants such translation is acceptable. "Polypeptide-nucleic nano-technology that underpins life on Earth – is ancient and efficient engineering. Multicellularity as an engineering design, just not as ancient."

      I am a molecular geneticist, in addition, cytology in oncology. These conclusions are based on extensive experience in the Biological Institute.

    • #104485
      scottie
      Participant

      canolan

      Well I may be wrong, but you have chosen a rather curious way to try to demonstrate your point.
      I assume that of the “countless ways” to make two systems communicate and do it more safely one way would be to take a lesson from the snake ie locate the olfactory system in the mouth and make the tongue more sensitive.

      You are aware are you not that the snake requires two senses of smell. One which involves the olfactory system located in the nose (not in the mouth as you have stated) and the other, the vomeronasal system that is associated with the constantly flicking tongue, which incidentally has no taste buds.This system is used in conjunction with the standard sense of smell possibly because the their rate of breathing does not allow the air to enter the nostrils fast enough to collect and translate scent particles in the normal way.

      I would suggest that just a cursory examination of the needs of the two (humans and snakes) explains the two different systems and in my subjective opinion as opposed to your subjective opinion there is nothing “clunky” about either system.

      However a far more fundamental point is at issue here.
      You contend that the human sense of taste and smell evolved from preexisting structures that constrained them so much that a better design was not possible.

      This raises two questions which I would appreciate you clarify
      (1)From what lineages were these preexisting structures inherited?
      (2)Can you provide the evidence for this please.

      Finally you are clearly using a designed piece of software to demonstrate how something can’t be designed because of design flaws. Am I right in assuming that this is the logic you are using to support you point, or am I missing a trick somewhere?

      I have read Stephen Gould quite extensively, I would be happy to discuss his book(s) later if you wish.

      Thanks

    • #104486
      scottie
      Participant

      sorry canalon for spelling error

      Not sure if posts can be edited for such mistakes

    • #104487
      BDDVM
      Participant

      Scotty,
      Where you see differences in doctrinal fundamentals I see differences in detail. The arguements you site are akin to whether ionic or doric collumns are better. They are both collumns.
      As for the vitreol and furvor you see in science are simply explained by the fact that humans are involved. Science is not devoid of bias but we make an effort to understand and mitigate those biases.
      If you espouse faith as a tool toward fact I would suggest it’s a tool with a very poor record.
      After all, If you have enough faith you can believe anything.
      As for my current understanding ( I avoid having beliefs, they are too hard to abandon when better evidence is presented) I see the tree of life as being very likely. One or a small handful of projenitors.
      Punctuated equalibrium vs gradualism? It depends on the situation(niche).
      Some situations cause fast change, some, don’t change and some change gradually.
      If you want to get a feel for real time evolutionary change I would suggest you read "The Beak of The Finch" by Jonathan Weiner
      about the Grants study of Finches in The Galopagos.
      It’s not overly technical so the main theme comes through well.

    • #104531
      scottie
      Participant

      BDDVM
      Sorry for the delay but I am a bit tied up on other matters and have not been able to get back to my computer.

      I will get back and respond tomorrow just as soon as I am free.
      I appreciate this discussion very much because a respectful exchange of ideas and thoughts is always refreshing.

      I will try to explain my point of view in order not to be misunderstood.

      To me science and faith are two different concepts.
      Science is limited to natural laws and any explanation must be confined within the limits of known natural laws.

      Now Darwin proposed a theory or model that explained the Origin of Species. Now because it could be tested within the confines of Natural laws it is a valid scientific theory simply because it can be falsified.
      He introduced the concept of Natural selection acting on random variation on given species that over time gradually change into another and different species. So this process can be tested and indeed has and continues to be.

      If I state that species arrived by an act(s) of a God i.e. by supernatural means then that statement cannot be tested in a scientific way and therefore cannot be regarded as a scientific theory,
      That is a belief system that I would be adhering to.

      Belief can and often is simply blind and doesn’t require evidence.

      Faith on the other hand is something more than belief.
      Faith should be based on evidence which maybe directly observed or by strong circumstantial evidence.
      In a court for example a person may be convicted of murder although no one actually witnessed the crime but other evidence allows the jury to conclude that the crime was committed by that person.

      So faith and belief are in themselves two different concepts although they are very very often used as synonyms.

      Now I don’t argue from a point of belief, nor indeed in matters of science do I argue from a point of faith.

      What I will try and explain tomorrow is why I argue the way I do, not from a standpoint of belief or faith but from the standpoint of corroborating evidence, because this is a science forum.

    • #104533
      canalon
      Participant
      quote scottie:

      Now I don’t argue from a point of belief, nor indeed in matters of science do I argue from a point of faith.

      What I will try and explain tomorrow is why I argue the way I do, not from a standpoint of belief or faith but from the standpoint of corroborating evidence, because this is a science forum.

      Now I prepare my self the popcorn and will settle in the seat and I am waiting impatiently to see the evidence for the existence for god and its implication in creation being presented. The trailer is good, I hope that the main feature will be up to the task. 8)

    • #104534
      BDDVM
      Participant

      Scotty,
      I think your definitions of faith and belief might be peculiar to you. In common usage faith refers to beliefs instilled by authority without evidence beyond the word of the authority. As a recovering catholic I can recount first hand the "because God said so" argument. Belief simply refers to ones understanding of reality regardless of how it came about.
      To argue another point, I feel that theology is a fine topic for science.
      The scientific process is the best tool we have to get to the truth. It isn’t perfect but it’s the best we have come up with yet.
      Besides, it was the creationists who claimed that they were scientists.

    • #104578
      scottie
      Participant

      Sorry for the delay but life is a bit hectic at the moment.

      Ok
      The theories of evolution attempt to describe the process by which species arrive.

      Now because we are discussing process it is important to understand which process you are subscribing to, as there are various differing theories.

      Hence my question as to which theory (process)you subscribe to.
      Since you have refrained to address the question I will assume you subscribe to the
      first of my descriptions I presented you with, i.e. the Darwinian concept of decent from a single common ancestor. This process of decent being by random mutations within the genetic mechanism and sifted by Natural selection. The whole process operates by the gradual accumulation of changes to produce new species.
      (If I am wrong please correct me.)

      Let me try and explain my understanding.
      The cell is a highly regulated biological information processing system that produces function. By it’s very nature this system is governed by the laws of information theory. Three essential ingredients are required.
      A coding system using symbols — the cell has that
      A decoding system recognising those symbols —- the cell has that
      And a channel for communication— the cell has that.

      This system uses the physical laws (physics, chemistry etc) to provide this function.

      Now you appear to have indicated that I concentrate on “doctrine” and you on detail.
      I am at a loss to understand how you could draw that conclusion, however lets look at some detail of the cell.

      In order for a eukaryotic organism to develop and form, cell division takes place.
      There are various stages to this cell cycle.

      The cell contains several control mechanisms that are referred to as checkpoints and these come into action at various stages of the cycle.

      These control mechanisms by their very nature check and verify whether the processes that led up to the particular stage are accurately completed before allowing progression to the next stage.

      An important function of many checkpoints is to assess DNA damage.
      When damage is found, the checkpoint uses a signal mechanism either to stall the cell cycle until repairs are made or, if repairs cannot be made, to target the cell for destruction via another mechanism.

      Now this is but a very small part of the control the cell exercises before it divides, but it is enough to reveal some fundamental points.

      (1) DNA damage (which is at the heart of Darwinian theory for speciation) is identified at virtually every stage in cell division and it is either repaired or it is passed on for destruction, except in some special situations. This demonstrates that decisions are being made by the cell, by way of biological algorithms, to eliminate the damage. Damage in the cell is regarded as noise in an information processing system which of course the cell is. Now engineers devote great time and effort to eliminate or at least reduce noise in any system, simply because noise corrupts information. Is it not strange that the very thing that corrupts information is being regarded as one of the fundamental driving forces of evolutional theory, of whatever shade?

      (2) Decision points or nodes like this, and there are several in the cell, where the process is directed one way or another cannot come about by chance because natural laws do not work this way. Laws are discovered because endless amounts of dynamic data can be reduced down into mathematical formula, and the reason this can be done is because the behaviour pattern being examined is highly ordered, fixed, and low in information. However degrees of freedom is exactly what is required by the cell systems in living organisms. So not even some yet undiscovered law can address this issue.

      (3) This is simply why I recognise design in biology. It has nothing to do with doctrine or belief or faith. It is about science.

      Now the argument has been put forward that bad design is evidence of randomness.
      However bad design can only be an example of bad design.

      Randomness cannot produce the prescriptive design we see in the cell. It is not scientifically possible.

      The analogy of the Panda’s Thumb sadly is the perpetuation of this myth.

      In 1978 Stephen Gould proposed this as an example of bad design to support his view that bad design is evidence of randomness. However he did not fully understand what he was examining, because he did not have the technology available to examine thoroughly.
      Some 20 years later however around 1998 and as technology had greatly advanced, his idea was put to the test and was found wanting.
      You will find the paper in Nature (peer reviewed of course) here
      http://www.nature.com/nature/journal/v3 … 309a0.html
      This is how the abstract reads
      “The way in which the giant panda, Ailuropoda melanoleuca, uses the radial sesamoid bone — its ‘pseudo-thumb’ — for grasping makes it one of the most extraordinary manipulation systems in mammalian evolution1, 2, 3, 4, 5. The bone has been reported to function as an active manipulator, enabling the panda to grasp bamboo stems between the bone and the opposing palm2,6, 7, 8. We have used computed tomography, magnetic resonance imaging (MRI) and related techniques to analyse a panda hand. The three-dimensional images we obtained indicate that the radial sesamoid bone cannot move independently of its articulated bones, as has been suggested1, 2, 3, but rather acts as part of a functional unit of manipulation. The radial sesamoid bone and the accessory carpal bone form a double pincer-like apparatus in the medial and lateral sides of the hand, respectively, enabling the panda to manipulate objects with great dexterity. (my emphasis)”

      The panda has specific needs (stripping bark off bamboo for some 12 hours a day is not an activity normally associated with other mammals)
      This is good design and therefore hardly an icon of bad design.

    • #104580
      scottie
      Participant

      Canalon

      By the way I am not trying to prove the existence of anything except design.
      You should not presume to ascribe motives to me. Don’t demonstrate fear of discussing science by trying to turn it towards some form of religion.

      Now how much pop corn do you have?
      Why not put it to good use and investigate evidences of Good design in Nature that science learns from.

      As the Whale turns
      http://www.naturalhistorymag.com/biomec … hale-turns
      Read the whole article you will learn something but here is a taster.
      “The Humpback Whale….
      And underwater, the animals move with such astonishing agility that they’ve caught the attention of naval engineers, who hope that some of the principles learned from the study of the humpback’s flippers can be applied to designing submersible vehicles of unprecedented maneuverability.”

      How about Heat exchanger Design
      Here is an acknowledgement from by Arthur P Fraas in his book “Heat Exchanger Design”
      You will find some extracts here
      http://books.google.com/books?id=rdtKXC … &q&f=false

      On page 2 he says
      “ It is interesting to note that nature presents us with one of the best examples of a highly efficient counterflow system in the blood vessel system in the legs of wading birds such as herons. The warm blood moving outward into the leg from the heart is passed through a system of tiny parallel blood vessels that are interspersed in checkerboard fashion with similar vessels returning from the extremity of the birds leg, giving one of the worlds most effective regenerative heat exchangers. The heat transfer performance of this blood vessel configuration is so good that the warm blood is cooled almost to the ambient temperature before reaching the region immersed in cold water, and thus the bird loses relatively little heat through the skin of it’s leg.”

      These are but a couple of examples of design that scientists and engineers look to, when designing their machines. I could go on about the seagull’s wings, the low drag design of the boxfish that the concept car imitates, the shock-absorbing properties of the abalone shells, or the sonar in dolphins etc etc.

      So many good ideas have come from nature that researchers have established a database that already catalogs thousands of different biological systems so that scientists can search this database to find natural solutions to their design problems.

      http://www.economist.com/node/4031083?story_id=4031083

      The June 9th 2005 edition of the Economist reports .. in part

      “This process is entirely the wrong way round, says Dr Vincent. “To be effective, biomimetics should be providing examples of suitable technologies from biology which fulfil the requirements of a particular engineering problem,” he explains. That is why he and his colleagues, with funding from Britain’s Engineering and Physical Sciences Research Council, have spent the past three years building a database of biological tricks which engineers will be able to access to find natural solutions to their design problems. A search of the database with the keyword “propulsion”, for example, produces a range of propulsion mechanisms used by jellyfish, frogs and crustaceans.”

      Now if Bad design is evidence of randomness as you argue to then do tell
      What is Good design evidence of?

      I would say Non-randomness, wouldn’t you or would your theology prevent that conclusion?

      Got any pop corn left? 🙂

    • #104581
      BDDVM
      Participant

      Scottie,
      Bad design is not evidence of randomness, it’s evidence of design by a non omnicient, non omnipotent designer.Its evidence of a design process that has limits in how perfect it can be because it has to start with designs that are preexisting.
      As for randomness not producing the designs we see in the cell. You seem to forget that only part of the process of evolution is random.
      The selection process brutally removes all organisms that don’t fit into an available niche.
      An analogy, Obviously it’s impossible for an industrial paint sprayer to paint the greek alphabet in 1” letters on a wall. ( the sprayer paints only a blast of paint 3ft wide) Unless you first mask off all of the wall that isn’t shaped like the greek alphabet. This makes a stencel that removes all the paint that doesn’t fit in the niche. Random paint, non random niche. In life the niche tends to be constantly changeing as well as the organisms that are fit in it.
      Variation (Random changes to current design) Selection (non random removal of designs that aren’t fitting) Reproduction. repeat a few quadrillion times.

      Now if you walk into a room and see the greek alphabet on the wall in 1 inch letters you can’t say that a random process wasn’t involved.
      You might say it appears that someone painted it on with a brush or it might have been done with a stensel. To determine which it was just look closely. A brush will leave brush strokes. The sprayer will show stippled paint and overspray.
      We are just saying that the often half baked bodged together designs we see in nature look like paint sprayer evidence not masterful brushstrokes.
      (awesome metaphore if I do say so myself)

    • #104677
      scottie
      Participant

      BDDVM
      Sorry for the delay. I have been away for a few days.

      I think you have misunderstood me.
      It’s not me that is suggesting bad design is evidence of randomness.
      This idea has been put out by canalon and you appear to agree with him.

      I was merely responding to his assertion. He appears not to answer any questions his assertions raise. So they are coming over as statements of doctrine, and I get very suspicious of doctrinaire pronouncements, because they invariably lack evidence or logic.

      When you say

      quote :

      “As for randomness not producing the designs we see in the cell. You seem to forget that only part of the process of evolution is random.”

      With respect there is nothing random at all about the cell process. I have explained, and any text book or peer reviewed paper will concur that as a fact.

      More than that I have also explained that any mistakes in copying are corrected before cell division takes place.

      Random mutations cannot produce the feedback processes we see in the cell. If you say they do then surely it is incumbent on you to show evidence of that.

      I am arguing that only design accounts for what we observe in the cell. You keep presuming that I am trying to bring religion into science.

      Why?

      After all my 13 year old grandson studies Design Technology in class and it is not a religious school.
      Design is a perfectly valid scientific topic.

      Is it your contention that unless the cell arrived by random mutations of the genetic material followed by natural selection, any other explanation must be religiously based.

      Could you please clarify your position.

    • #104679
      BDDVM
      Participant

      First all mutations are not repaired, most are repaired, a few kill the cell and an extremely tiny fraction give the cell something it didn’t have before.
      It might be your use of the term design that is confusing me. When you say design do you imply a designer that is an entity?
      The process of evolution is a design process without an entity guiding it.
      This design process has actually been used recently to design robots and some software.
      Random processes (Mutation) can result in feedback systems in cells. A well studied system is called the lac operon. It’s a bacterial system for regulating when certain DNA segments are expressed and when they aren’t. Because it is such a simple system it takes less imagination to see how it evolved.
      It is not my contention that designer based explainations are religeously based. It is however consistent with all my previous experience.

    • #104720
      scottie
      Participant
      quote :

      First all mutations are not repaired, most are repaired, a few kill the cell

      Yes the cell proof reading catches most errors and corrects them. Only rarely, as in such cases as in cancer will a new mutation lead to a phenotype so dramatic that we will realise that something new has happened. Note of course that the new mutation is invariably deleterious. At best these mutations are neutral.

      Is there any mutation observed that has resulted in beneficial phenotypic change? If so
      Could you please point me to any peer reviewed paper to confirm that.

      btw. please think for a moment, do natural laws proof read for errors?

      quote :

      When you say design do you imply a designer that is an entity?

      The best way for me to answer that is by referring to the lac operon that you cite
      as an example this way

      quote :

      Because it is such a simple system it takes less imagination to see how it evolved.

      Firstly to suggest that this is a simple system so that less imagination is required, I find quite astonishing.
      May I suggest you review the actual operation of this lac operon. Here is a good visual of what it does and how.

      http://highered.mcgraw-hill.com/olc/dl/120080/bio27.swf

      If bacteria encounter two sugars, e.g. glucose and lactose, then E. coli cells will keep the lac operon turned down as long as glucose is present. It is not appropriate if glucose is still available, because E. coli cells metabolize glucose more easily than lactose, it would therefore be wasteful in energy for them to activate the lac operon in the presence of glucose.

      This operon is therefore described as a combination of switches, and that is exactly what it is.
      Now switches are decision nodes that allow a process to go one way or another depending on what the circumstances require.

      There is nothing simple about this system. It requires informational signalling from both within and without the cell. That symbolic signalling determines which switch sequence to turn on or off and when, along with energy saving decisions

      We see algorithmic commands such as START, STOP, AND, OR, ELSE and so on
      in operation. These things are never seen in natural laws.

      We still don’t understand how these genes come to grouped in the way they are on the genome except that this grouping is definitely non random, as a clear understanding of the operon shows.

      So this is not haphazard design at work. This is clearly design to cater for different energy sources, functioning with a definite purpose in mind.

      It is definitely not a simple system

      However by way of comparison lets consider the circular settings of the large upright stones at Stonehenge in England. Some of these massive stones have equally massive cross member stones perched on top.

      How did this massive configuration come about?
      Does anyone believe that is was the result of natural forces?
      And why not ?— after all we have seen for ourselves how in the recent tsunami heavy vehicles being perched on top of buildings in a matter of minutes demonstrating that natural forces do have the capacity to deposit heavy structures on top of others.

      But we don’t believe these came about naturally, because we recognise functional design in the configuration. It is simple and it could even be argued that it is not a very good design. Still we attribute it to an outside agency. We don’t know who that outside agency was but yet in the science of archaeology it is carefully studied and accepted that outside agency is definitely involved.

      Now can science identify a designer? Well the simple answer is that science cannot.
      A historical record can, but that is not a scientific topic.
      Also a historical record may or may not be true.

      Now

      The Churches of Christendom claim that their Triune creator did it.
      The Islamic churches claim that their creator did it.
      The Hindus claim their creator(s) did it.
      The Church of the Flying Spaghetti Monster claims their creator did it, and so on.

      These are simply belief systems and therefore cannot be falsifiable in the scientific sense and therefore are not subjects for scientific debate, even though many try to make it so.

      However the creator we call decent with modification by random mutations/natural selection claims to be scientific and not a belief system.
      Therefore it must be, by it’s very definition, falsifiable.

      Please ask yourself this question
      Why are there so many different theories about the origin of species i.e. macro evolution?

      The answer must be because each theory is simply not fitting the evidence, an essential requirement of any scientific theory.

      Just about every facet of evolutionary theory is being falsified time and time again.
      This is not a dogmatic statement because the peer-reviewed material is abundant showing this to be so. The interesting point about this material is that most of it is coming from the evolutionary community itself.

      I am quite happy to point you to any necessary papers to confirm my argument.

    • #104727
      BDDVM
      Participant

      First, falsefiable doesn’t mean false. It means a theory that can be tested. If I say, Santa Claus lives at the North Pole. That is falsefiable. You just have to look. Anyone who wants to can look for themselves.
      If you say, God just talked to me and told me that I am the new Pope therefore all that cool stuff in the Vatican belongs to me. That isn’t falsefiable. God only talks to me, sorry.
      You appear to have a common problem among creationists. A very limited imagination. I have little choice but to assume you are in the creationist mindset as you dodged my question about an entity designer.
      The lac operon has only a handful of parts, non of which will mean instant death if it’s missing. Once the bits of the system finally get together in the same E coli it gives a very nice advantage of not wasting recources on lactose metabolic machinery when it’s not needed. It’s just a few mutations. No need to get God involved. Just give the little beasties some time.
      I’ve often wondered why God tells his chosen people that they are chosen but neglects to tell everyone else.

    • #104728
      BDDVM
      Participant

      As for Origen of species. First you have to realise that the concept of species itself is a human construct. There, I said it, I think it’s kind of a red herring. Many will argue with this. That’s fine, It doesn’t mean that we need a God to explain life. It’s another of those detail arguments that some would use to invalidate all of Biology.
      As for just about every aspect of evolutionary theory being falsefied, Well to put it cordially, Male Bovid Feces.
      If you want to see selection,reproduction, mutation happen in a short period of time. You can do it yourself. Petri dish, bacterial culture, pick an antibiotic, apply it to the plate for a while. What you will see is a large percentage of the initial population die off and are replaced by a new population of bacteria that are more resistant to the antibiotic in question. (unfortunately they will likely also get resistant to several other antibiotics due to how a lot of bacteria share resistance factors).
      If you don’t believe this happens I would invite you to take good old fashioned penicillin for your next staph infection.
      As you appear to have about the average amount of preexisting bias about this experiments outcome I would suggest you team up with someone who will be able to counter your conscious and unconscious biases with appropriate controls. (scientific method)

    • #104759
      scottie
      Participant

      Thank you for your two posts
      Let me start by responding to the first.

      quote :

      First, falsefiable doesn’t mean false. It means a theory that can be tested

      You are actually making my point for me.
      For a theory to be considered scientific it must be falsifiable and if evidence is produced to rebut the theory then the theory must be abandoned or at least modified.

      However when I present valid scientific arguments that the theory does not and indeed cannot explain, you launch into anti-religious rhetoric. You don’t even know what my belief system is or even if I have one. I have no idea what all this "chosen people" rhetoric is all about

      So can we just stick to science please.

      You stated that the lac operon is a simple example of evolution.

      In fairness you have tried to expand upon that by adding

      quote :

      The lac operon has only a handful of parts, non of which will mean instant death if it’s missing. Once the bits of the system finally get together in the same E coli it gives a very nice advantage of not wasting recources on lactose metabolic machinery when it’s not needed. It’s just a few mutations. No need to get God involved. Just give the little beasties some time.

      Firstly, and with great respect, that does not even begin to explain how some pre existing structure whatever it may have been, came to be, what is known as the lac operon.

      It’s just a few mutations you say. Is that really the best “scientific” explanation you can come up with?
      Simply stating that a few mutations did it is frankly no different the “god did it argument”.

      Secondly lac operon is evidence of the system’s built in redundancy that enables E coli to exist on different energy sources.
      Redundancy in any system is evidence of forward planning and which is of course evidence of design.

      Random mutation by their very nature cannot forward plan.

      Another biological fact you need to appreciate is that mutations invariably are deleterious, at best neutral, to the organism. There has been enough experimental evidence over the past at least 60 or so years, to establish that point.

      If you wish I will point you some of the research that has been carried out.

    • #104760
      Darby
      Participant

      Beneficial mutations –

      http://www.ncbi.nlm.nih.gov/pubmed/16396175

      http://www.csun.edu/~sd51881/readings/E … l_1996.pdf

      http://www.jstor.org/pss/2411188

      How duplication and preservation increases the chances of beneficial mutation while preserving original function (something that would look to the uneducated like "forward planning") –

      http://www.ncbi.nlm.nih.gov/pmc/article … 101175.pdf

      That took all of 5 minutes searching.

    • #104761
      scottie
      Participant

      Thanks Darby

      At last someone has decided to engage in some real science.
      I was beginning to wonder if the anti-religious flow towards me was ever going to change to genuine science. So once again thanks

      Firstly this discussion is in relation to origin of species not the evolution within species which no one that I am aware of disputes.
      As I understand it even the creationists recognise this fact.

      You claim it took you about 5 minutes to locate these papers, but did it take you 5 minutes to actually read them.

      Please point me to any one of them that shows how a new species has emerged.
      All these mutations observed did not produce any new species.

      Did any of the beneficial mutations produce phenotypic change required for a new species?
      I think you already know the answer to that.

      Two of these papers includes the very good work of Richard Lenski with some collegues.
      http://www.ncbi.nlm.nih.gov/pubmed/16396175
      and
      http://www.csun.edu/~sd51881/readings/E … l_1996.pdf

      Now the latter is particularly interesting, however you have chosen a more dated paper of Lenski.

      This paper from 1996 refers to his experiment with E.coli, but what is pertinent is that the paper in it’s opening paragraph refers to the Stephens Gould / Niles Eldridge theory of punctuated equilibriam to explain the origin of species. They developed this theory in response to the fossil record in Cambrian strata that even Darwin himself acknowledged was a real problem for his theory.

      Now I would suggest you read his more recent paper(2008) relating to this experiment that was conducted over more than 22 years and involving some 600,000 generations of E.coli growth in 12 population groups.
      http://myxo.css.msu.edu/lenski/pdf/2008 … t%20al.pdf

      And what appears to be his concluding paper on this experiment (2011)
      http://www.microbemagazine.org/images/s … 000030.pdf

      In the 2008 paper in his concluding comments he asks the question
      “Will the Cit and Cit lineages eventually become distinct species?”

      Clearly up to that point the answer was no.

      Lets move on to 2011 and his accolade to Darwin
      Lets again go to his concluding comments relation to his long experiment to show how Darwin’s theory of the origin Species was being supported by his experoiments.
      After all these long years of painstaking experimenting he enters what he terms his midlife crisis.
      “From Bacteria to Computers,and Back Again
      Perhaps it was a midlife crisis: my bacteria were slowing down, and I was looking for some new action. So I had an affair—one that continues today, though with slightly less feverish intensity—with some artificial creatures. Avidians are computer programs that copy their own genomes, and they live in a virtual world that exists inside a computer.”

      No new species then.
      So he has given up on the real world and goes to a virtual reality.

      Your third citation
      http://www.jstor.org/pss/2411188
      far from showing that random mutations cause new species attempts to demonstrate that these random mutations tend more to immunise species from extinction.. As I read it therefore stasis rather than evolution in the order of the day.

      Finally your last citation is simply a hypothesis.
      I don’t see how using one hypothesis to support another can be classed as empirical evidence.
      I think you will find that things have moved on since 1998

      But thanks for your response.
      Much appreciated.

    • #104767
      BDDVM
      Participant

      Scotty,
      In order to see new species you must do a few things. First define species, relatively easy for sexually reproducing organisms, very difficult for bacteria. Bacteria would be nice because of the relatively short time per generation but the definition problem makes this a non starter.
      The best place to look would likely be African rift lake Cichlids. They have been spinning off new species at a very fast rate. Still it’s going to likely take 10’s of years.
      Another place to look is in a very small system like Darwins finches in the Galopago islands. "The Beak of The Finch" chronicles the Grants’ herculean multiyear study of these finches separating into 3 species during bad years and hybridizing back into one big genetic blob during high rainfall years. It’s quite readable. They actually captured, measured, and followed every single bird on the Island for many years.
      I’m still curious about your version of a designer. Please describe, I can’t argue with your beliefs/biases if you won’t define them. Are you ashamed of your beliefs? Incidentally, I find that saying your biases out load helps to see alternatives more clearly. It seems to help take some of the emotion out.
      The reason I don’t site peer revieved papers in this forum is that I agree with Albert Einstien when he said (aproximately) You can’t say you understand a theory until you can explain it to your grandmother.

    • #104798
      scottie
      Participant

      BDDVM
      Sorry once again for the delay in responding. I have a very busy life and it does take me away from the forum often for days at a time. I have the weekend ahead so can devote more time to this discussion.

      quote :

      First define species, relatively easy for sexually reproducing organisms, very difficult for bacteria. Bacteria would be nice because of the relatively short time per generation but the definition problem makes this a non starter.

      You are right about the need to define species.
      Now I can only rely on biologists who provide that definition.
      As you say with sexually producing organisms it is fairly well defined.
      In the case of bacteria it could perhaps be more subjective.

      However I can only take on board what biologists themselves say.
      When Richard Lenski who is (was) in the forefront of bacteria investigation in connection with the evolutionary process says quite clearly that no new species had emerged in the course of his investigation, he clearly had a definition in mind.

      The E.coli he started with was still E.coli when he concluded.

      quote :

      Another place to look is in a very small system like Darwins finches in the Galopago islands. “The Beak of The Finch” chronicles the Grants’ herculean multiyear study of these finches separating into 3 species during bad years and hybridizing back into one big genetic blob during high rainfall years. It’s quite readable. They actually captured, measured, and followed every single bird on the Island for many years.

      Now I am familiar with the Grants work.
      As far as I am aware all the finches they were studying are sexually reproducing and able to reproduce with each other.
      Am I correct?

      So,are you saying that finches with different size beaks are now being regarded as different species. Is that correct?

      This is how this forum defines species

      quote :

      Species
      Definition
      noun, singular or plural: species
      (taxonomy)
      (1) The lowest taxonomic rank, and the most basic unit or category of biological classification.
      (2) An individual belonging to a group of organisms (or the entire group itself) having common characteristics and (usually) are capable of mating with one another.

      Supplement
      A species is given a two-part name: the generic name and the specific name (or specific epithet). For example, Allium cepa (commonly known as onion)
      http://www.biology-online.org/dictionary/Species

      Now according to this definition are all the finches, that the Grants or indeed Darwin himself studied, of the same species or not?

      What you are mistakenly doing is noting variation within a given species depending on environmental conditions and promoting it as evidence of one species changing into another.

      The finches still remained finches.
      Lenski’s E.coli bacteria still remained E.coli bacteria.

      quote :

      I’m still curious about your version of a designer. Please describe

      Natural Laws can and do produce design. A good example of this is the snowflake.
      This site describes nicely how the design in snowflakes is produced.
      http://chemistry.about.com/od/molecules … wflake.htm

      So one “version of a designer” is Natural Laws and as the site above shows this design can be explained scientifically.

      There is another type of design, for example the cell. The Design clearly seen in it’s operation cannot be explained by natural laws alone. Natural laws are in operation but are controlled by what are referred to as biological algorithms.

      Algorithms by their very nature are the product of an outside agency.
      So the question is, what is that outside agency?
      This is a question that science is simply unable to answer because analytical science can only describe natural phenomena.

      So I have two “versions of a designer”. One science can describe and the other science cannot describe.

      Now regarding the latter a description of this outside agency must naturally be a matter of belief and not science. That belief can be regarded as a religion or philosophy and therefore cannot be analysed by the scientific method.

      Let me remind you that this discussion is about a scientific theory(s).

      Now I can understand why you appear to want to move this debate on to belief systems because on a scientific basis the argument for species change (origin) by natural phenomena is being lost.

      All the arguments you are putting forward are based on a philosophical approach and not as I am arguing, a scientific one.
      Some would regard that as a religious approach.

      The reality is, you don’t need to know what I believe, to show that what I state is scientifically incorrect. All you have to do is produce the evidence that rebuts my statements.

      quote :

      The reason I don’t site peer revieved papers in this forum is that I agree with Albert Einstien when he said (aproximately) You can’t say you understand a theory until you can explain it to your grandmother.

      So please tell, what are you doing making statements you claim are based on science and in a scientific forum if you are not prepared to support them with any recognised scientific evidence. (Although once again you contradict yourself because you refer to the Grant studies of finches)

      btw The standard theory i.e. "decent from a common ancestor by random mutation and natural selection" is quite a simple theory and one that my grandson understands. Not sure about my grandmother!

      If something is factual you will be able to show it with evidence, if you cannot then it is a belief .
      Why not just admit that what you have been arguing is based on a belief system.
      That would be a consistent way of presenting your point.

    • #104799
      BDDVM
      Participant

      New species created in lab. May 3 issue Proceedings of National Acadamy of Sciences.
      I do not agree that Religeous/ Phylosophical beliefs are beyond the reach of science. If it comes out of someones mouth it’s biased BS until the scientific process has been applied. Even then look at it a couple thousand more times.
      I can’t disprove or prove your beliefs if you refuse to tell me what they are. Why? are you ashamed? Worried that you might have to rethink your world view?
      This is the strongest, most insideous bias there is. Being emotionally invested in your theory.
      To test for this bias, simply immagine how you would feel if someone were to prove to you that your beliefs are wrong.
      I know , I know, there is no way to disprove the existence of a deity.
      But hypothetically, Say a giant intergallactic spaceship arrived and the inhabitants mentioned that they dropped off some bacteria here 3 billion years ago and were just stopping by to see how things were going.
      How would you feel?
      The most biased statement ever. "I’m not biased, you are."

    • #104810
      scottie
      Participant
      quote :

      New species created in lab. May 3 issue Proceedings of National Acadamy of Sciences.

      Really now you simply need do better than that.

      “New species created in Lab”
      Hasn’t the obvious struck you?

      An outside agency was required for whatever the result was.
      That is precisely the nub of my argument relating to species formation.
      Don’t you realise you are making my point for me.

      I of course assume you are referring to the “Long-term evolution of Pseudomonas in the human host” article. Even the article does not make the claim you are attributing to it. So please at least report these experiments without any philosophical spin to buttress your arguments.

      You keep going on about my beliefs, so let’s put you out of your obvious frustation.

      Now you have stated you couldn’t not respond to my enquires because you did not understand theory enough to be able to explain it.

      So you don’t really understand what you actually believe.

      However I understand exactly what I believe.

      I believe in the veracity of the Scientific method.

      Here is my understanding of this method and I am very clear about it.
      The essential elements of a scientific method are :-
      Operation – Some action done to the system being investigated
      Observation – What happens when the operation is done to the system
      Model – A fact, hypothesis, theory, or the phenomenon itself at a certain moment
      Utility Function – A measure of the usefulness of the model to explain, predict, and control.

      One of the elements of any scientific utility function is the refutability of the model. Another is its simplicity, on the Principle of Parsimony also known as Occam’s razor.

      quote :

      If it comes out of someones mouth it’s biased BS until the scientific process has been applied.

      I assume you include your own mouth in this analysis.

      quote :

      This is the strongest, most insideous bias there is. Being emotionally invested in your theory.

      I understand your point completely. Your emotions are coming over in a very obvious manner.

      quote :

      To test for this bias, simply immagine how you would feel if someone were to prove to you that your beliefs are wrong.

      I am still waiting. Please keep trying.

    • #104824
      canalon
      Participant
      quote scottie:

      BDDVM
      Sorry for the delay. I have been away for a few days.

      I think you have misunderstood me.
      It’s not me that is suggesting bad design is evidence of randomness.
      This idea has been put out by canalon and you appear to agree with him.

      I was merely responding to his assertion. He appears not to answer any questions his assertions raise. So they are coming over as statements of doctrine, and I get very suspicious of doctrinaire pronouncements, because they invariably lack evidence or logic.

      Sorry not to have pushed further, but I had to recover from surgery and then had to get back to work. But I will once again try it.

      The whole point of the bad design argument is not that bad design is evidence of randomness but that it is evidence of a complete lack of planning, foresight and generally what we call design in nature. See the ancester of bears had a thumb, but they lost it. Then came the Panda and a thumb would have been useful, and instead of taking the old very good design of a thumb, something else had to evolve. But there was no coming back, it had to come from something that was still there in the panda’s genetic toolbox.
      The argument is that if there was design, the reliance on necessity and on what is there, instead of what is available in the life’s toolbox in general is proof that there is no overarching design, plan(ner) or anything that can select from what is available at large. And the selection is limited to what is genetically available. That makes sense in the framework of evolutionnary biology, this is stupid if your hypothesize that there is a designer behind things.

      And I see that you are using the old Occam’s razor saw a bit down thread. You know the "a designer is a simpler explanation that random accumulation of unlikely event yada yada yada…" kind of argument. Would you care to tell us where the designer comes from? because if there is one, it must come from somewhere, no? And we now have a very interesting recursive loop in the making, that does not appear to be any more probable than random accumulation of rare events followed by selection.

    • #104826
      BDDVM
      Participant

      Wrong article, It’s the one about the lizards.
      It describes a new species of parthenogenic lizards created by hybridizing two related lizards. This is proof of concept for these lizards producing a plethora of related species, both parthenogenic and sexaully reproducing.
      Yes I am Biased. I know that and keep it constantly in mind and pay careful attention to how it feels.
      Are you claiming a lack of bias?
      So you are telling me that the fact that species have never been seen diverging and the fact that species have now been seen diverging are both arguements for intelligent design?

    • #104827
      scottie
      Participant

      I take it then you mean this one
      http://arstechnica.com/science/news/201 … he-lab.ars

      It describes a new species of parthenogenic lizards created by hybridizing two related lizards.

      Here is a clue for you
      This article is based on the paper entitled.
      Laboratory synthesis of an independently reproducing vertebrate species.” By Aracely A. Lutes, Diana P. Baumann, William B. Neaves, and Peter Baumann. Proceedings of the National Academy of Sciences, Vol. 108. No. 18, May 3, 2011.

      Now I could go into the details of the paper, but the obvious stands out so clearly that I don’t need to dig into it, and here is why.

      Hybridization is the cross breeding of related organisms within a given species.
      It also involves the input of an outside agency (i.e. the researcher) which is what this research experiment is all about.

      Has a new species been created?
      Let me refer you back to how this forum defines species.
      (1)The lowest taxonomic rank, and the most basic unit or category of biological classification.
      (2) An individual belonging to a group of organisms (or the entire group itself) having common characteristics and (usually) are capable of mating with one another.

      The sloppy use of this term species can lead to any amount of slight of hand conclusions, if that is where one wishes to go.

      Please read the abstract I have provided here
      http://www.pnas.org/content/early/2011/ … 8.abstract

      Go to the Materials and Methods of the paper to understand the degree of outside input that was required to arrive at their destination
      You notice I use the word destination. Why?
      Because there was a purpose to this experiment.

      Since when has random mutations had a purpose.
      Natural selection even, does not come into play.
      Artificial selection however does.

      You are trying to use artificial input and artificial selection to prove randomness.
      What sort of logic is this?

      Of course an outside agency can modify the genetic material of an organism to create a different species. (if of course that agency has the capacity.)

      That is my point. It requires an outside agency.

      I am arguing for design in biology. I don’t need to preface the word with adjectives, be it (un)intelligent, apparent, good bad or whatever.

      The biological algorithms we see operating in the cell fit perfectly within the requirements of analysis by the scientific method.
      And algorithms by their very nature are not the product of natural law. They use natural laws towards a specific function or purpose.

      Now if you can demonstrate any of the evolutionary models to fit into the scientific method of analysis, then you have a genuine scientific theory.

      If you cannot then you have, at best a hypothesis that is not standing the test of the scientific method.

      Now in fairness you have declared a bias toward this hypothesis of whatever model and
      I don’t have a problem with that and do sincerely respect your viewpoint.

      All I ask is that you do not present it as science, because then I have to take issue.

      You ask
      Are you claiming a lack of bias?

      We all could be guilty of having a bias.
      What sticking to the scientific method does in any analysis, is to remove any bias.

      Now if you can show me where I have strayed outside the scientific method in any analysis
      I have presented I will correct it.

      I have no problem in being corrected. I have found through experience, that being corrected is one of the best forms of learning.

    • #104828
      BDDVM
      Participant

      Your definition of hybrid is wrong. To be a hybrid the parents must be different species. (again we have the species definition to contend with).
      and it does happen in nature. The new species isn’t the same as either of the parent species and is self replicating.
      If it’s not a new species created by means common in nature, what is it?
      Obviously, this is kind of a back door way to create a new species but it is a way that can be accomplished in a short time and is therefore amenable to recreation in the lab.
      As I said it’s a proof of concept showing that this group of related lizards could have arisen by simple hybridization.
      As for how selection takes place, natural, sexual,domestication, they all work to shape the gene pool. Arguments about which takes precidence I think are silly semantics. Selection is Selection.
      Could be guilty of bias? No No No. Always bias, all day every day.
      There are still a huge number of people who believe President Obama was not born in Hawaii despite the documentary proof they asked for. As soon as you think you are unbiased then bias has you in it’s insideous grasp.
      The hallmark of bias is the inability to take in information that would endanger the comfortable world view that creates the bias. You litterally have to make an effort to see the evidence.

    • #104829
      scottie
      Participant

      canalon

      Sorry to hear about your surgery, I do hope you are on a good trajectory back to full health.

      I understand the argument you are making but it lacks coherence.
      Let me explain

      quote :

      The whole point of the bad design argument is not that bad design is evidence of randomness but that it is evidence of a complete lack of planning, foresight and generally what we call design in nature.

      You appear to completely ignore any evidence that does not fit your ideas.
      The analogy of the “Panda’s thumb” is sheer nonsense and although being refuted is still being perpetuated as evidence of as you now put it of a complete lack of planning, foresight and generally what we call design in nature.

      Now really please read the paper if you haven’t taken the trouble already.
      You will find the paper in Nature (peer reviewed of course) here
      http://www.nature.com/nature/journal/v3 … 309a0.html

      quote :

      This is how the abstract reads
      “The way in which the giant panda, Ailuropoda melanoleuca, uses the radial sesamoid bone — its ‘pseudo-thumb’ — for grasping makes it one of the most extraordinary manipulation systems in mammalian evolution1, 2, 3, 4, 5. The bone has been reported to function as an active manipulator, enabling the panda to grasp bamboo stems between the bone and the opposing palm2,6, 7, 8. We have used computed tomography, magnetic resonance imaging (MRI) and related techniques to analyse a panda hand. The three-dimensional images we obtained indicate that the radial sesamoid bone cannot move independently of its articulated bones, as has been suggested1, 2, 3, but rather acts as part of a functional unit of manipulation. The radial sesamoid bone and the accessory carpal bone form a double pincer-like apparatus in the medial and lateral sides of the hand, respectively, enabling the panda to manipulate objects with great dexterity.

      (my emphasis)”
      The panda has specific needs (stripping bark off bamboo for some 12 hours a day is not an activity normally associated with other mammals)
      If the panda evolved as you describe ( I will come back to this later) of what better use would the ordinary thumb be over the ‘pseudo-thumb’. Can you explain?

      The environment, the diet and the eating habit of the panda required forward planning and foresight as you say and that is what we see.
      But it is not just this digit that is evidence of forward planning for particular diet and eating habits.
      Here is a description of the digestive system you will find here
      http://factsanddetails.com/china.php?it … ubcatid=68
       

      quote :

      The panda oddly enough is a carnivore not an herbivore: its stomach and intestines are adapted for meat and its teeth are so strong they can chew through metal. The panda esophagus has a tough, horny lining to protect it from sharp, bamboo splinters. The stomach is thick and muscular and gizardlike. The rest of the digestive system is similar or that of other carnivores but because it doesn’t eat meat is lightly used.
      Pandas don’t have a specialized gut like cows and deer for breaking down fibrous material. To get enough nourishment from the relatively nutrient-free bamboo, the panda has a stomach like a conveyor belt. Food is barely chewed, only 17 percent of it is digested, compared to 80 percent for most herbivores, and it passes through the body in as little as five hours. After a panda has sat in one place for a while it is not uncommon for it leave behind seven to nine kilograms of woody, spindle-shaped droppings. On average a panda produces 13 kilograms of droppings a day.
       Japanese researchers have found a bacteria in panda dung that has shown to be more effective in breaking down organic garbage than almost any other known substance. In one experiment the bacteria broke down 100 kilograms of waste into three kilograms after 17 weeks, producing only water and carbon dioxide as by products. The researchers discovered the bacteria and found 270 other kinds of microbes in panda dung they received from a zoo.

      No forward planning eh. It’s all randomness is it?
      Now let me come on to this idea of common decent.

      You say

      quote :

      See the ancester of bears had a thumb, but they lost it.

      This is just sheer speculation and you know it.
      If I were to ask you ( but I wont because you not not be able to give me one) who or what was this ancestor of the bears, you would not be able to give one.
      Why?
      Because there is no evidence for this.

      This idea of a common ancestor is based on a Doctrine that has run it’s course and is now being rejected by some of the most prominent biologists.

      Among such ones as Carl Woese and many many others there is Eugene Koonin of the National Center for Biotechnology Information, National Library of Medicine, and National Institutes of Health
      Koonin is widely regarded and is certainly at the center of the scientific establishment.
      In 2007 he presented a paper which is online here
      http://www.biology-direct.com/content/2/1/21

      It is entitled
      "The Biological Big Bang model for the major transitions in evolution."
      May I urge you to read it please and not continue to be taken in by this myth of common decent.
      Only the priesthood of Darwinian doctrine continue with this myth.

      Now let me respond to your final little bit of rhetoric

      quote :

      And I see that you are using the old Occam’s razor saw a bit down thread. You know the “a designer is a simpler explanation that random accumulation of unlikely event yada yada yada…” kind of argument. Would you care to tell us where the designer comes from? because if there is one, it must come from somewhere, no? And we now have a very interesting recursive loop in the making, that does not appear to be any more probable than random accumulation of rare events followed by selection.

      Do you accept Kepler’s Laws of motion? – Of course you do
      Do you accept Newton’s Laws on gravity — Of course you do
      Do you accept Maxwell’s Laws on Electromagnetism – Of course you do

      Did Kepler or Newton or Maxwell make those laws? Do tell please — who?
      But you accept them all without knowing don’t you?

      So instead of all your

      quote :

      yada yada yada

      let us make a deal

      You tell me who made those Laws and I will tell you who designed the cell.

      Deal?

    • #104830
      canalon
      Participant

      Scottie,

      Your point about the adaptation of the panda’s thumb is irrelevant. It does not prove design, just adaptation. Interestingly I would point that the carnivorous and wasteful digestive system of said animal is once again a good argument for its link with other bears (who are all carnivorous). The adaptation of its digestive flora is once again irrelevant to the point, it does adapt. And frigging quickly. Observing variation of any individual digestive flora over time (and even more so if its diet is modified) is easy. Understanding waht happens is another story, though…

      As for the laws of physics, nobody designed them. They are the consequence of the interaction whatever constituted the primordial soup of the Big Bang.

      But who designed your designer? I do not give a shit who or what it is, but if it has the power to interact with our world, it comes from somewhere. Yet we know that it cannot come from nothing as design is essantial to anything. So who designed your designer?

      See that is why it is dangerous to play with a razor, you can hurt yourself.

    • #104831
      BDDVM
      Participant

      I’m still waiting to hear more about this designer. Who, what, when ,where, how?

    • #104873
      scottie
      Participant

      BDDVM

      Since you are having trouble with a definition of species why don’t you sort out in your own mind what constitutes “a species” and then we can continue our discussion.

      canalon

      Oh dear
      Did you really think this one through?

      quote :

      As for the laws of physics, nobody designed them. They are the consequence of the interaction whatever constituted the primordial soup of the Big Bang.

      Is this supposed to be an explanation based on science?

      Your confusion in the mixing of two concepts from two different hypothesis reveals more about what you don’t understand, than about what you do understand.

      The primordial soup is the start point from which Darwin formulated his Origin of species hypothesis. Somehow life came into being from some chemicals.

      No one has even figured out what this so called soup consisted of. Scientists have only been able to speculate as to what it may have consisted of.

      The most fundamental law in biology is that life comes only from another pre-existing life.

      Louis Pasteur clarified this law of Biogenesis about 150 years ago. I take it you did learn about this at school.( Incidently, Pasteur and Darwin were contemporaries.)

      Funny that eh ! Darwin hypothesising that life started from a chemical soup and Pasteur showing through science that it couldn’t.

      But hey why let science stand in the way of a good story.

      Now
      The Big Bang hypothesis starts with a mathematical concept called Singularity.
      Singularity has no physical existence.

      Monsignor Georges Lemaître a Belgian Catholic priest proposed the Big Bang hypothesis.
      Of course it had a few rather basic problems so in 1980 Alan Guth bolted on his hypothesis which we know as Inflation theory to try and make some sense of the Big Bang but created even more problems.

      By the way George Lemaitre also believed that the Virgin Mary was assumed body and soul into heaven at her death.

      Do you now understand the difference between these two theories? Good
      So now lets go a little further

      Now you should at least know this one.

      The most fundamental law in physics is the law of the conservation of energy.
      In the natural world neither matter nor energy can be created or destroyed.

      Therefore either matter and energy has had no beginning (i.e. it has always existed, the concept of infinity)
      OR
      it was brought into existence as a consequence of an action outside the physical world.

      Since infinity is simply a mathematical construct and has no physical existence the latter must apply.

      That is why our Catholic priest thought up this hypothesis to explain how his god would have have created the universe.

      So your answer is both scientifically wrong and religiously based.

      Your confusion reveals not your science but your religion.
      And all religions have dogmas.
      So would you like to try again

      Once you have absorbed this little lesson we can continue with our science class.

    • #104874
      BDDVM
      Participant

      I’ll make you a deal. I’ll define Species when you define your designer.
      I can’t help but wonder why you are reluctant to define your designer.

    • #104907
      scottie
      Participant

      I am able to get back to the forum for the weekend and
      Yes I accept your deal
      Design
      to create, fashion, execute, or construct according to plan or purpose

      Examples of designers in the natural world
      Birds – constructing a nest
      Ants – constructing a anthill
      Etc,etc.

      Examples of religion’s chief designers (supposedly)
      Christendom’s Triune god
      Islam’s Allah
      Hindu’s Vishnu
      Egyptian’s Amon
      Evolution’s Random mutation
      Etc, etc, etc,

      Examples of human designers
      Isambard Kingdom Brunell — bridges
      Isaac Newton — telescope
      Robert Oppenheimer — atomic bomb
      Etc, etc, etc.

      Now Regarding the designer of the cell.

      I am not able to define the designer, any more than I can define the maker of the natural laws.
      Neither can you or anyone else.
      That is why I was able to confidentially offer the deal canalon.

      However what I find amusing are the arrogant assumptions some have who claim they can, only to find that when their claims are put to the test and found wanting, they have to try and change the debate to one of belief or religion.

      Science does not need to define the designer of anything to acknowledge the fact that design is there.

      Religions however by their nature have to, in order to attract believers.

      However you can as indeed I can define an understanding of species.
      There is enough information around to be able to do this.

      So do tell please what is it? I have already given you my understanding.

    • #104908
      BDDVM
      Participant

      WRONG, If you posit a designer it is incumbant on you to define as much as you can and attempt to prove/ disprove it.
      "I believe in a designer that can design the cell." doesn’t cut it.
      and they say survival of the fittest is a tautology.
      I am only interested in practical theories. Does your designer currently do anything? Will any more designs be forthcoming? Does your designer have any interest in helping or hurting me?
      If your designer is beyond the reach of scientific investigation then they might as well be in a different universe and anything said about them is pointless speculation (Phylosophy).
      The designer positted by modern biology is well defined. Mostly (if not completely) random changes in the genetic material of preexisting organisms ( or almost living chemical systems capable of some crude form of replication) provide variation in the population. Selection (natural, sexual, domestication) removes variations that don’t fit in an available niche. The remaining organisms reproduce. Repeat, repeat ,repeat.
      Things you wouldn’t expect to see. Perfection, this process is a little messy. Completely new designs with no previous history. Virgin birth
      (Spontaneous generation)
      Notice I don’t mention your arguement. Complexity is not evidence against this process. Life doesn’t violate any thermodynamic laws.
      Organic molecules are perfectly capable of creating bizarrely complex systems without intelligent input.
      If you find a watch on the beach it is perfectly logical to look around for the owner/maker. If however you find a crab on the beach there is no reason to look for it’s creator. It’s pretty likely other crabs were involved.

    • #104934
      scottie
      Participant

      First things first

      quote :

      “I believe in a designer that can design the cell.”

      If you are going to quote me then do it accurately. Please don’t attribute comments to me I have not made.

      This is what I wrote. “Now Regarding the designer of the cell.” And it was in In response to your question
      Nowhere will you find that I have said “I believe in a designer”

      The only belief I have clearly enumerated is that I believe in the veracity of the scientific method. I also stated my understanding of the scientific method.

      It seems very clear now that you are trying very hard to engage in a philosophical debate.

      I have repeatedly stated that the cell displays all the evidence of functional design and not the product of random variation.

      I have also stated quite clearly that random mutations cannot produce the functional design clearly observed in cell operations and have given scientific reasons why this is so.

      Now if the reasons I have provided can be shown to be scientifically inaccurate then please do correct me. If not then my argument stands, because it is based on scientific and not wishful thinking.

      You are still evading the issue of species definition so I will give up on getting that from you. 🙂
      However you have committed to a definition of the

      quote :

      “The designer positted by modern biology”

      You state

      quote :

      The designer positted by modern biology is well defined. Mostly (if not completely) random changes in the genetic material of preexisting organisms ( or almost living chemical systems capable of some crude form of replication) provide variation in the population. Selection (natural, sexual, domestication) removes variations that don’t fit in an available niche. The remaining organisms reproduce. Repeat, repeat ,repeat.

      Now I must presume that you regard this to be a statement of scientific validity.
      So let me examine it.

      quote :

      ( or almost living chemical systems capable of some crude form of replication)

      Could you explain what are “almost living chemical systems” ?

      Also please describe what you mean by “some crude form of replication”?

      quote :

      Mostly (if not completely) random changes in the genetic material of preexisting organisms provide variation in the population.

      This part of your definition is about variation within existing population is it not?

      quote :

      Selection (natural, sexual, domestication) removes variations that don’t fit in an available niche. The remaining organisms reproduce.

      This again is about variation within an existing population is it not?
      You appear to be agreeing with me,

      quote :

      Things you wouldn’t expect to see. Perfection, this process is a little messy. Completely new designs with no previous history. Virgin birth
      (Spontaneous generation)

      This is simple rhetoric that doesn’t seem to make a great deal of sense.
      Are you saying that Virgin birth (whatever that is) is spontaneous generation?

      quote :

      Notice I don’t mention your arguement. Complexity is not evidence against this process.

      Whose is arguing that complexity is evidence of design. Design can be simple or complex and I gave examples in my previous post.

      Please address what I am writing and not make up arguments you wish to attack. I think they are called straw man arguments.

      quote :

      Life doesn’t violate any thermodynamic laws.

      Who say’s it does?

      quote :

      Organic molecules are perfectly capable of creating bizarrely complex systems without intelligent input.

      How?

      quote :

      If you find a watch on the beach it is perfectly logical to look around for the owner/maker. If however you find a crab on the beach there is no reason to look for it’s creator. It’s pretty likely other crabs were involved.

      Do you not see the obvious contradiction between this statement and your opening statement.

      quote :

      WRONG, If you posit a designer it is incumbant on you to define as much as you can and attempt to prove/ disprove it.

      So if the design of crab is as you claim the product of random mutations and natural selection then it is also as you put it
      “incumbant on you to define as much as you can and attempt to prove/ disprove it.”

      So how does the mechanism of random mutations produce the biological algorithms we observe in the cell?

      Now here is an example of such a algorithm.

      IF lactose present. AND glucose not present. AND cell can actually synthesize active LacZ and LacY. THEN transcribe lacZYA from lacP ...

      You will find an explanation of this here

      http://books.google.com/books?id=WSf1FF … 22&f=false

      Now if you have any difficulty in understanding how algorithms work don’t worry I will explain it all scientifically.

    • #104935
      BDDVM
      Participant

      Apparently it boils down to the fact that you can’t imagine or can’t allow yourself to imagine that these complex systems, algorhythms if you will, evolved.
      I and the rest of the scientific community have no problem imagining this evolution process producing all the life we see, both alive and extinct. There is a reason it’s considered one of the greatest theories ever.
      Don’t get too hung up on the species concept, evolution obviously doesn’t.
      I apologize for misquoting your apparent arguments about a designer.
      You’ve left some significant gaps in your definition which I had to guess at. I was left assuming that you fall into the catagory of creationist/ Intelligent designist. If this is not true I sincerly apologize. If it is true just say so and quit avoiding putting your beliefs out where they can be debated.

    • #104936
      canalon
      Participant

      So if I understand your problem with evolution:
      – The cell, or living organisms cannot have arisen de novo because nothing comes from nothing
      – And self organizing complexity cannot arise spontaneously from chemistry alone
      Ergo There must have been something that designed it.

      But you cannot say what that designer might be, or where it comes from, or anything substantial about it. So your Scientific conclusion is that there must be a designer because you cannot imagine anything else, but because you are a scientist you will not say anything about it because that would be philosophy. Great. I am temepted to say that once summarized your argument is a bit crap.

    • #104945
      scottie
      Participant

      BDDVM

      quote :

      I and the rest of the scientific community have no problem imagining this evolution process producing all the life we see, both alive and extinct.

      You have summed up your position very well indeed. It is all in your imagination.
      I respect you for acknowledging that.

      Also you are right about me. I don’t have those imaginative powers. It is a failing I have I must admit.

      quote :

      Don’t get too hung up on the species concept, evolution obviously doesn’t.

      Now this is a very interesting statement. Am I not correct in understanding that your position is Darwinian based. Is it not also true that his seminal work is entitled “ Origin of Species….”. I have read his work and the term species keeps coming up with almost monotonous regularity. Very strange!!!!

      quote :

      I was left assuming that you fall into the catagory of creationist/ Intelligent designist.

      Why are you left assuming?
      This is what I wrote on the 14th April.

      quote :

      by scottie » Thu Apr 14, 2011 9:57 pm

      But before we go any further I would like to make one thing clear. I am neither a creationist nor an advocate of the ID community.

      I have made a study of the various denominations of evolutionary thinking, and there are several, and all coming up with separate ideas.

      I have similarly made a study of the bible though not the Qu’ran and the religious churches of Christendom and Islam again come up with different ideas, each one claiming they are right.

      Science is my interest.
      Science in my opinion should not be tied to any philosophy.

      Now how much clearer do you wish me to be?
      I would be happy to sign some kind of affidavit if you wish. 🙂

      However apologies accepted.

      quote :

      If it is true just say so and quit avoiding putting your beliefs out where they can be debated.

      My belief system is out there to be debated but you don’t appear to want to.

      Why are you having such a problem with my belief in the veracity of the scientific method?

      I appreciate you don’t have the same faith in it’s veracity as I do, but my faith is very much evidenced based.

      That is why I have gone to such great lengths to provide the information from science papers and publications to demonstrate my absolute confidence in my belief.

    • #104946
      scottie
      Participant

      canalon

      quote :

      So if I understand your problem with evolution:
      – The cell, or living organisms cannot have arisen de novo because nothing comes from nothing
      – And self organizing complexity cannot arise spontaneously from chemistry alone
      – Ergo There must have been something that designed it.

      You’re looking through the wrong end of the telescope.

      I don’t have any problems with evolution. I know evolution occurs. I also know the limits of what it can accomplish and what it cannot.

      With respect you are the one with the problems. You don’t accept the limits that prevent speciation but are unable to support that understanding with evidence.

      You still adhere to the idea of common decent and yet molecular biology now demonstrates that this hypothesis has been falsified. I have provided you with the evidence and you take no note. I can do no more than to keep trying to educate.

      quote :

      And self organizing complexity cannot arise spontaneously from chemistry alone

      That is correct, however it does not have to be very complex.

      There is a tendency for some to confuse self ordering with self organising.

      Self ordering can and does happen. Tornadoes and whirlpools are examples of self ordering, and chaos theory well explains those phenomena.

      Self organising however, of which the cell is a prime example cannot be explained by the action of any natural law(s). The origin of the codes operating within the cell can only be speculated at because natural laws do not produce the symbolic information that is clearly evident.

      quote :

      But you cannot say what that designer might be, or where it comes from, or anything substantial about it. So your Scientific conclusion is that there must be a designer because you cannot imagine anything else, but because you are a scientist you will not say anything about it because that would be philosophy. Great. I am temepted to say that once summarized your argument is a bit crap.

      You are right I cannot define the designer of the cell. But then nor can you. You tried to demonstrate how natural laws came about and look at the hopeless tangle you got yourself into.
      Come on now be honest, you made a right pigs ear of it didn’t you?
      Nothing to be ashamed of though, science can’t answer questions like that, you were just a little bit silly to try.

      Religions however supposedly can. All they have to do is construct a dogma and that explains it. Darwinism has become a dogma, no differently.

      Now I know this cuts across your belief system, but you are making the claim that you have science on your side.

      When I explain and show that you don’t have science on your side, it gets frustrating and shows up in your deteriorating language.

      Finally, on this question of naming the designer, May I relate a little sad story from about October 2001.

      Three very hardworking guys discovered a quite amazing control system and were put up to receive a prize for all their hard work and ingenuity.

      However the prize panel while recognising their tremendous work realised it fell significantly short because they were unable to tell who was the designer of the system. Sadly therefore this system had to be classified as non-designed in the same way as the wheel or the abacus.

      However the panel did feel they deserved some recognition so they awarded them a consolation prize.

      You will find the whole sad tale here
      http://nobelprize.org/nobel_prizes/medi … press.html

    • #104947
      canalon
      Participant

      Scottie,

      You miss the point, I do not care if you are a creationist, an IDiot, or simply thick. What i am trying to argue is that the theory of evolution is the only theory that fits and explains life as we see it. If you argue that self organization cannot happen, you have to explain where the organization comes from, what the designer is in other word. It is not a name that I want, but an idea of what the designer is, where it comes from. The point is that your affirmation that self organization is impossible, besides lacking demonstration, throw your reasoning in a recursive loop, and I am curious to know how you get out of it.
      But if you provide a reasonned and undestandable model for design, I promise that I will definitely reconsider my views on evolution. Right now however, you seem limited to say that there must be a designer and therefore evolution is wrong. Sorry that does not work. Offer something consistent.
      As for your story it is simply irrelevant to the discussion.

    • #104948
      BDDVM
      Participant

      I’m fascinated with this designer. Please can we have some details that we may use to make our daily lives better.

    • #104983
      scottie
      Participant

      canalon

      quote :

      But if you provide a reasonned and undestandable model for design, I promise that I will definitely reconsider my views on evolution.

      That is a very reasonable question so let’s see if I can provide a scientifically satisfying answer.

      I will start with an illustration in symbolic representation. Please bear with me.

      A person walking past a house notices the roof is on fire. He also is aware that someone is in the house. He has no way of communicating with the householder as he is a deaf mute.

      He notices that the front yard is laid with loose pebbles.
      He goes into the yard and arranges some of the pebbles of a particular colour to read.
      “Roof on fire Get out”
      The householder reads the pebbles and escapes.
      Now what has gone on here?

      The yard pebbles in themselves have no meaning. They are inert, just lumps of pebble molecules.

      The passer-by arranged some of the pebbles in such a way as to put a meaning into them. In other words he coded some of the pebbles to convey meaning.

      Now the householder had to decode the pebble arrangement. IF he could not understand written English, the message would be meaningless to him. In other words the pebbles would have remained inert to him because he could not decode the pebble arrangement and therefore no function (his escape) would take place.

      This is the essence of Shannon communication.
      A Coder is required – the passerby
      A Channel of communication required – the pebbles
      A Decoder is required – the householder.

      There is another element that needs to be considered. NOISE.

      If for instance the pebble arrangement starts to get messed up due to wind or heavy rain or the householder simply running across it, the arrangement begins to get corrupted. This is noise. Now the coder would have to keep rearranging the pebbles to retain meaning.

      The important thing to keep in mind is that the pebbles in themselves carry no meaning. They are inert.
      The meaning that is put into the arrangement comes from outside—The passer-by.
      He uses a code (written English) and importantly the householder understands that code and can act on it.

      Now it is this method of communication that the cell uses.

      Here is an example of a fairly simple regulatory system.

      The lac operon in E. coli and other bacteria is an example of a simple regulatory circuit. In bacteria, genes with related functions are often located next to each other, controlled by the same regulatory region, and transcribed together; this group of genes is called an operon. The lac operon functions in the metabolism of the sugar lactose, which can be used as an energy source. However, the bacteria prefer to use glucose as an energy source, so if there is glucose present in the environment the bacteria do not want to make the proteins that are encoded by the lac operon. Therefore, transcription of the lac operon is regulated by an elegant circuit in which transcription occurs only if there is lactose but not glucose is present in the environment.

      http://ocw.mit.edu/courses/electrical-e … note01.pdf

      James Shapiro describes refers to this simple but excellent example of cell coding for function.

      "IF lactose present AND glucose not present AND cell can synthesize active LacZ and LacY, THEN transcribe lacZYA from lacP."

      The symbols IF AND THEN in this simple functional code have meaning but that meaning in NOT in the molecules themselves.( as in the pebbles) As James Shapiro himself says. They are inert.
      http://shapiro.bsd.uchicago.edu/21st_Ce … _Evol.html ( Please spend some time reading it. You will find it very instructive.)

      The expression THEN is what is referred to as a Decision Node. These nodes are required in a genetic algorithm for function to take place. Without these decision nodes natural laws take everything forward and is explained very well in chaos theory.

      Notice also the expressions IF and AND. These expressions introduce potential into the algorithm. (the algorithm looks forward to note if a particular situation exists and IF it exists then move forward this way). Now when potential is recognised in an algorithm then natural mechanistic laws cannot be involved in that decision making process simply because moving forward takes the course of the algorithm and not natural law.

      Now the meaning of these symbols comes from the cell itself.
      A good question can be …
      How did that meaning come about? But that question does not hinder the science of trying to understand how the cell works. Does it?

      If you read David Abel’s and Jack Trevor’s paper “Three subsets of sequence complexity and their relevance to biopolymeric information”
      You will find it here
      http://www.tbiomed.com/content/2/1/29

      They clearly show that this symbolic meaning cannot arrive in any natural materialistic way and have shown why this is not possible even in theory.

      They have put forward 4 Null Hypothesis and invites them to be falsified.
      To date there has been no success.
      Science only deals with the materialistic world of natural laws.

      Shapiro uses the expression Natural genetic engineering because he philosophically wants the answer as to the origin of this process to come from a naturalistic cause. If you removed the adjective Natural from his descriptions of cell functions, the explanatory power of his papers does not diminish in the slightest.

      Is there anything wrong with his use of that adjective? Well NO.
      It just needs to be recognised what the science is and what the philosophy is.

      All too often the boundary between science and philosophy gets very very blurred.

      Darwinian evolution that has developed into today’s Modern Synthesis is in reality a Null Hypothesis. This null hypothesis is being falsified by the science of molecular biology.

      Random mutations cannot produce symbolic representation. Random mutation is the NOISE that degrades symbolic representation. The cell’s genetic engineering repair systems work at eliminating that noise.

      The irony of this is, that noise in an information channel degrades the information content and engineers spend great time and effort in reducing that noise in order to maintain clarity of information. Darwinian theory on the other hand is based on noise being the instrument that drives forward progress.
      It totally contradicts Shannon information theory.

      Practically every molecular biologist around the world is discovering what James Shapiro is so ably presenting, in showing that the Darwinian process is simply not the mechanism that explains speciation. That mechanism is simply not known.

      In my next post in a couple of hours I will try and provide another example that visually is more instructive.

    • #104984
      canalon
      Participant

      And will you make any progress toward answering the question?

      "If design cannot be spontaneous, where/how did the designer originate?"

    • #104986
      scottie
      Participant

      Let’s take another example but this time with far more selective power. I will try to make it more visually descriptive to demonstrate the process.
      tRNA biosynthesis
      DNA molecule carries the instructions which are absolutely necessary to produce enzymes, different nucleotide complexes, and smaller protein molecules used in the processes of transcription and translation. One of such important tools are tRNA molecules. Each living cell constantly utilizes some 40 different forms of the tRNA molecule.

      We will look at the yeast DNA gene for tRNA tyr
      The tRNATyr gene has to be found in one of the chromosomes. Here that gene is represented with the aid of the four symbols A, C, G, T, substituted for the rather complex chemical formulas of four the different deoxyribonucleotides:

      Here it is.
      GTTATCAGTTAATTGACTCTCGGTAGCCAAGTTGGTTTAAGGCGCAAGACT GTAATTTACCACTACGAAATCTTTGAGATCGGGCGTTCGACTCGCCCCCG GGAGATT

      Don’t worry about the exact meaning of this sequence just note the configuration changes as they come along.

      The DNA gene has to be copied (transcribed). The gene remains intact in the structure of the given chromosome. The subunits of the copy are made from a different kind of sugar (not deoxyribose, but ribose), and one of the original organic bases (T) is substituted by another one (U):

      So the early RNA transcript of the gene is

      GUUAUCAGUUAAUUGACUCUCGGUAGCCAAGUUGGUUUAAGGCGC AAGACUGUAAUUUACCACUACGAAAUCUUUGAGAUCGGGCGUUCG ACUCGCCCCCGGGAGAUU (notice the T’s are now U’s)

      Both the tRNATyr gene and its faithful RNA copy consist of four different units linked in a sequence 104 subunits long. Now this may seem to us quite random, but in fact it is absolutely non-random, i.e. this specific sequence is closely correlated with the final, functional properties of the tRNATyr molecule. Virtually any change in this sequence makes it unfit to fill properly its job in the cell.

      This non-randomness is usually called selectivity.

      This RNA copy dictated by the structure of the tRNATyr gene undergoes many further complex modifications before it changes into the functional primary or mature structure of the tRNATyr molecule.
      Parts of the precursor 1 copy have to be removed. The removed elements are written in lowercase red

      guuaucaguuaauugaCUCUCGGUAGCCAAGUUGGUUUAAGGCGCAAGA CUGUAAuuuaccacuacgaaAUCUUUGAGAUCGGGCGUUCGACUCGCCC CCGGGAGAuu

      Which give us Precursor 2

      CUCUCGGUAGCCAAGUUGGUUUAAGGCGCAAGACUGUAAAUCUUU GAGAUCGGGCGUUCGACUCGCCCCCGGGAGACAA

      Several single units have to undergo a transformation. The transformed elements are the final, functional primary structure of the yeast tRNA Tyr

      CUCUCGGUAGmCCAAGDDGmGDDDAAGGCGmCAAGACUGPsAAiA
      PsCUUUGAGADCmGGGCGTPsCGAmCUCGCCCCCGGGAGACCA

      Have a look again at the early RNA transcript of the tRNA gene dictated by the sequence of the DNA gene the early RNA transcript of the gene – the supposedly unique source of information

      GUUAUCAGUUAAUUGACUCUCGGUAGCCAAGUUGGUUUAAGGCGC AAGACUGUAAUUUACCACUACGAAAUCUUUGAGAUCGGGCGUUCG ACUCGCCCCCGGGAGAUU

      The final, functional primary structure of the yeast tRNATyr differs considerably from the original DNA gene.
      It is shorter than the gene – just 78 subunits long, but it is composed not from four but from eleven different subunits.

      The original DNA gene is simply a very rough and incomplete information set that is required to produce the function it is required to. It has to be modified

      The process of modifying the raw precursor involves a considerable increase in the selectivity of the product. This increase is over 1000 fold.

      In other words the selectivity guaranteed by the DNA gene is insignificantly small in comparison with the selectivity really needed and actually somehow provided.

      So where does this enormous selective power reside? We don’t know.

      About 14 years ago mRNA editing was discovered. This means that the DNA genes, in some cases, do not determine the proper sequence of amino acids. The information provided by DNA messages is – in these cases -simply wrong, from the functional, biological point of view, and it has to be edited during a separate stage. As a result of this editing the original, primary molecular meaning of a given gene can be radically changed.

      If DNA is the main ruling agency of the body mechanisms, then any mutilation of the DNA molecule should be fatal and unrecoverable. In reality DNA can, and is constantly being repaired. Somehow the organism knows how to detect a change in the genetic message, and utilizes many different, complex procedures to repair different forms of mutation.

      Here is another spanner in the works of the one gene one function concept
      http://www.sciencemag.org/cgi/content/a … +One+Codon,
      As the abstract concludes
      “Thus, the genetic code supports the use of one codon to code for multiple aminoacids.”

      In linguists we have homonyms, one word having two meanings. The meaning is determined by the context. ( bear –an animal but also to carry something) the context determines the meaning.)
      So here we have the cell displaying a quasi-linguistic capability.

      How did that meaning come about? Also where does that algorithm reside.
      The simple answer is we do not know.

      The present, almost completed inventory of the cell certainly does not contain any complex set of structures that we can identify with this type decision making code (and there are countless numbers of this information storage)

      In a computer for instance we find these algorithms written onto the hard drive. But with the cell we have no idea as yet where these algorithms reside.

      What is clear though is that symbolic information that is so clearly evident has to come from somewhere. It does not reside in the chemical nature of the molecules.

      Random mutilation of DNA for example does not provide the prescriptive information that we see in cell operation.
      In communication theory mutilation of any data is regarded as noise. And noise corrupts the signal. That is why such care is taken to eliminate noise from a communication channel..

      So what we are seeing in these two examples are features of operations we would expect in genetic engineering design. As James Shipiro describes it Natural Genetic Engineering.

      Please reflect on his concluding submission entitled
      A 21st Century View of Evolution.

      In part he states

      The last half century has taught us an astonishing amount about how living organisms function at the molecular level, in particular about how they execute cellular computations through molecular interactions and about the systemic, modular, computation-ready organization of the genome. We have come to realize some of the basic design features that govern genome structure. Combining this knowledge with our understanding of how natural genetic engineering operates, it is possible to formulate the outlines of a new 21st Century vision of evolutionary engineering that postulates a more regular principle-based process of change than the gradual random walk of 19th and 20th Century theories. Such a new vision is not all-encompassing because it cannot provide detailed accounts for major events currently beyond the reach of science, such as the origin of cellular life or the mechanisms of endosymbiotic events underlying the emergence of distinct superkingdoms and kingdoms of life (51, 52). Nonetheless, a 21st Century view of evolution can help us understand how new taxonomic groups have emerged bearing novel complex adaptations.

    • #104988
      BDDVM
      Participant

      And your point is…..

    • #105010
      scottie
      Participant

      Canalon

      quote :

      And will you make any progress toward answering the question?

      “If design cannot be spontaneous, where/how did the designer originate?”
      Patrick

      This question is very confusing.

      Where have I stated that design cannot be spontaneous?

      May I remind what your original question was.

      quote :

      But if you provide a reasonned and undestandable model for design, I promise that I will definitely reconsider my views on evolution.

      This is what I am in the progress of dealing with. So I will continue.

      Now I deliberately waited a while before continuing in the hope that you would read the papers I have cited.

      IF you have then you will know the answer to the question raised. However for the sake of clarity in case you have not fully absorbed the information I have presented.
      Allow me to quote directly from his (Shapiro’s)paper that incidentally has referenced some 56 other papers and articles in support of his presentation.
      Here is the paper again
      http://shapiro.bsd.uchicago.edu/21st_Ce … _Evol.html

      Under the heading
      A 21ST CENTURY VIEW OF EVOLUTION

      "The last half century has taught us an astonishing amount about how living organisms function at the molecular level, in particular about how they execute cellular computations through molecular interactions and about the systemic, modular, computation-ready organization of the genome. We have come to realize some of the basic design features that govern genome structure.
      Combining this knowledge with our understanding of how natural genetic engineering operates, it is possible to formulate the outlines of a new 21st Century vision of evolutionary engineering that postulates a more regular principle-based process of change than the gradual random walk of 19th and 20th Century theories.

      Such a new vision is not all-encompassing because it cannot provide detailed accounts for major events currently beyond the reach of science, such as the origin of cellular life or the mechanisms of endosymbiotic events underlying the emergence of distinct superkingdoms and kingdoms of life (51, 52).

      Nonetheless, a 21st Century view of evolution can help us understand how new taxonomic groups have emerged bearing novel complex adaptations."

      He then summarises in the following way

      "� Major evolutionary change to the genome occurs by the amplification and rearrangement of pre-existing modules. Old genomic systems are disassembled and new genomic systems are assembled by natural genetic engineering functions that operate via non-random molecular processes.

      � Major alterations in the content and distribution of repetitive DNA elements results in a reformatting of the genome to function in novel ways –without major alterations of protein coding sequences. These reformattings would be particularly important in adaptive radiations within taxonomic groups that use the same basic materials to make a wide variety of morphologically distinct species (e.g. birds and mammals).

      Large-scale genome-wide reorganizations occur rapidly (potentially within a single generation) following activation of natural genetic engineering systems in response to a major evolutionary challenge. The cellular regulation of natural genetic engineering automatically imposes a punctuated tempo on the process of evolutionary change.

      � Targeting of natural genetic engineering processes by cellular control networks to particular regions of the genome enhances the probability of generating useful new multi-locus systems. (Exactly how far the computational capacity of cells can influence complex genome rearrangements needs to be investigated. This area also holds promise for powerful new biotechnologies.)

      � Natural selection following genome reorganization eliminates the misfits whose new genetic structures are non-functional. In this sense, natural selection plays an essentially negative role, as postulated by many early thinkers about evolution (e.g. 53). Once organisms with functional new genomes appear, however, natural selection may play a positive role in fine-tuning novel genetic systems by the kind of micro-evolutionary processes currently studied in the laboratory."

      He concludes this way

      "Molecular genetics has amply confirmed McClintock�s discovery that living organisms actively reorganize their genomes (5). It has also supported her view that the genome can "sense danger" and respond accordingly (56).
      The recognition of the fundamentally biological nature of genetic change and of cellular potentials for information processing frees our thinking about evolution. In particular, our conceptual formulations are no longer dependent on the operation of stochastic processes. Thus, we can now envision a role for computational inputs and adaptive feedbacks into the evolution of life as a complex system. Indeed, it is possible that we will eventually see such information-processing capabilities as essential to life itself."

      In 2009 Shapiro revisited this subject and you will find his paper here.
      http://shapiro.bsd.uchicago.edu/Shapiro … 0Dogma.pdf
      This time citing 154 reference articles.
      Under
      Natural Genetic Engineering
      Underlying the central dogma and conventional views of genome evolution was the ideathat the genome is a stable structure thatchanges rarely and accidentally by chemicalfluctuations or replication errors. This view has had to change with the realization that maintenance of genome stability is an active cellular function and the discovery of numerous dedicated biochemical systems for restructuring DNA molecules.

      Genetic changeis almost always the result of cellular action on the genome. These natural processes are analogous to human genetic engineering, and their
      activity in genome evolution has been extensively documented.

      In summary therefore
      The mechanism for genetic change is the natural genetic engineering process Shapiro describes.
      Old genomic systems are disassembled and new genomic systems are assembled by natural genetic engineering functions that operate via non-random molecular processes.
      Basic design features are now recognised
      Major change occurs suddenly (potentially within one generation and supported by the fossil record)

      You will notice that although Shapiro acknowledges the design engineering process. He also states that it’s origin is currently beyond the scope of science.

      If you want to persist in your argument of having to name or describe a designer, for the process to be credible, then your argument against the evolutionary community itself.
      Because Shapiro is an evolutionary biologist and so are a great number of scientists who also recognise this process.

      There are a reducing number of biologists who still subscribe to the Darwinian process of random mutations.
      The main protagonists are notably Dawkins and Coyne who seem more interested in promoting their religious views rather than science.

    • #105011
      BDDVM
      Participant

      So, if not random mutations, what? Do you suggest corn is consciously redisigning itself ? To me it just looks like another aspect of the Red Queen. (Keep the rate of change in your genome at least as high as your parasites or be replaced by someone who does.)

    • #105049
      canalon
      Participant

      Scottie, if there is design, there is intent or a designer.
      You have been arguing that randomness cannot explain the complicated funcctions that are observed in every life form, and that as consequence life has to be designed.
      So once again:
      who/what is the designer of life, and where did it itself come from.

      I am not interested in the rest. you are dodging the essential question and your longwinded evasions are tiring.

    • #105055
      BDDVM
      Participant

      Come on Scottie at least give us a hint about the designer. The suspense is killing me. Or are you just trying to manufacture some "controversy among the scientific community".

    • #105067
      scottie
      Participant

      BDDVM

      Well you have lost the argument on science and so you are reduced to sarcasm.
      OK so that is your method of debate. I’ll run with you then.

      quote :

      So, if not random mutations, what?

      Now despite all the evidence, are you really still running with random mutations? 🙂
      Oh dear I was hoping your claim to be a person of science had some merit.
      You might just as well swap “random mutations” with “The Flying Spaghetti Monster” . 🙂

      canalon

      quote :

      You have been arguing that randomness cannot explain the complicated funcctions that are observed in every life form, and that as consequence life has to be designed.

      No no you have it wrong.
      I havn’t been arguing that randomness cannot explain..
      I have been proving it.

      quote :

      I am not interested in the rest. you are dodging the essential question and your longwinded evasions are tiring.

      I take it then you are not interested in the evidence that science provides.
      My “long winded evasions “ as you put it are the product of actual empirical evidence provided by peer-reviewed papers from the scientific (evolutionary) community and what is more you have not provided a single refutation.

      Come on admit it, you know you have lost the scientific argument so your only avenue of escape now is to change the subject to your religion. But as I have said before I don’t do religion.

      I know it hurts to be shown up on actual science, especially when so much emotional energy has been invested in a belief that is coming apart at the seams.

      The Pope has the same problem you know, so don’t feel too isolated, you are in good company.:)

      Look isn’t it better to acknowledge you are wrong than to religiously stick to a dogma that simply does not stack up.

      Science progresses through the falsification of previously held views or hypotheses.
      In fact it is this kind of falsification that elevates true science from a lot of the claptrap that so pervades life.

    • #105071
      BDDVM
      Participant

      Still no hints about the nature of the designer?
      How can your theory be falsified if you refuse to give any details?
      Some direct questions about your designer.
      Currently designing? or Finished designing a long time ago?
      Intelligent being?
      Does the designer have any interest in my well being?
      None of these questions should take more than a few words to answer.(this forum doesn’t work well with long arguements.)

    • #105074
      scottie
      Participant

      Here is a short reply

      Do you wish to discuss science or religion.

      Which?

      Because my understanding is that this is a science forum?

    • #105075
      JackBean
      Participant

      scottie: you came up with the designer, so don’t ask whether to discuss science or religion and answer the questions.

    • #105076
      scottie
      Participant

      BDDVM

      Let ‘s try and understand what science can or cannot do.

      This is really primary school stuff and I genuinely thought I was in discussion with an intellect beyond this level, but apparently not.

      So let’s take for example my Honda Accord vehicle.

      Science can determine that it has been designed by someone and manufactured by someone, because firstly it has function, also because it has parts that have the attributes of manufacture. It has circuitry and a computer system that has feedback loops etc. It has heat exchange systems that again have the attributes of design etc etc etc.

      That is what science can tell you. Actually it is pretty much a matter of common sense is it not.

      However science cannot tell you who designed or manufactured it.
      That information can only come from some form of historical record.

      What is so difficult to understand?
      This is something an eight year old child can understand.

      Now the cell has all the attributes of design. That is not in question.
      Any biologist will affirm that.

      The question is not whether it is designed.
      The question is whether that design can come about by random mutations.
      The theory of random mutations claims to be a scientific theory, therefore it can be examined by the scientific method to determine whether that can be so.

      Now I have at very great lengths presented the evidence from within the scientific community to demonstrate that random mutations cannot produce the attributes of function we observe in the cell.

      You have not been able to scientifically refute any of my posts.

      Now many of the religions of this world claim to know how this came about.
      However they cannot demonstrate it through the scientific method, therefore they rest their case on a belief system and those beliefs are founded on Dogmas which adherents hold dear.
      That much is clear is it not.

      The problem you have is that you also have a Dogma which is random mutations, but the difference is that you claim it to be scientifically based.

      That is where your problem is, because when the scientific method is applied to this Dogma it fails the test.

      Now no end of sarcasm and cat calls will alter this very simple fact.

      If you say that this is what you believe, then that is a very different matter, simply because a belief system, or philosophy or religion takes this matter beyond science.

      What I have done is not present a theory of design.
      I have presented facts that demonstrate the cell is designed.
      Now who or what designed it is beyond the reach of science.

      To determine who or what designed it must be a matter of an historical record and not a scientific record.

    • #105077
      BDDVM
      Participant

      I simply don’t aggree that your designer is beyond the reach of science.
      Therefore I am requesting some information about your designer.
      I’m afraid "I don’t believe in your theory and I won’t tell you mine." sounds a little juvenile.

    • #105078
      JackBean
      Participant
      quote scottie:

      So let’s take for example my Honda Accord vehicle.

      Science can determine that it has been designed by someone and manufactured by someone, because firstly it has function, also because it has parts that have the attributes of manufacture. It has circuitry and a computer system that has feedback loops etc. It has heat exchange systems that again have the attributes of design etc etc etc.

      Actually, that has no attributes of design, but attributes of creation, but doesn’t tell you anything what has created it. Whether it was someone or the previous generation of Hondas.

    • #105089
      scottie
      Participant

      I really don’t understand why you are having such difficulty in recognising the obvious

      Darwin introduced historicity into science. Evolutionary biology, in contrast with physics and chemistry, is a historical science – the evolutionist attempts to explain events and processes that have already taken place. Laws and experiments are inappropriate techniques for the explication of such events and processes. Instead one constructs a historical narrative, consisting of a tentative reconstruction of the particular scenario that led to the events one is trying to explain.
      The discovery of natural selection, by Darwin and Alfred Russel Wallace, must itself be counted as an extraordinary philosophical advance.

      All you have to do is recognise that natural selection is a philosophical concept. No different from the philosophical concepts of other religions.

      What is the problem?

    • #105090
      JackBean
      Participant

      probably recognizing, that it’s only philosophy, since you can have experiments to confirm or not the evolution. Even more, you can see it in the nature.

    • #105091
      scottie
      Participant

      JackBean

      quote :

      Darwin introduced historicity into science. Evolutionary biology, in contrast with physics and chemistry, is a historical science – the evolutionist attempts to explain events and processes that have already taken place. Laws and experiments are inappropriate techniques for the explication of such events and processes. Instead one constructs a historical narrative, consisting of a tentative reconstruction of the particular scenario that led to the events one is trying to explain.
      The discovery of natural selection, by Darwin and Alfred Russel Wallace, must itself be counted as an extraordinary philosophical advance.

      What I wrote (the above)in my last post is a direct quote from Ernst Mayr himself in his lecture of 1999
      You will find that lecture here
      http://www.biologie.uni-hamburg.de/b-on … luence.htm

      One of the founding fathers of the modern synthesis proudly hails Darwinism as a philosophy.
      You are now taking on Ernst Mayr, well good for you.

    • #105092
      JackBean
      Participant

      that’s nice example, how context may change meaning.

    • #105093
      BDDVM
      Participant

      Phylosophy is the intellectual persuit of truth. Science is a rather recent and far more effective tool than the biased hand waving(and coersion) of the past. Scottie, stop the evasions,long winded obfuscations and name dropping. Just explain your theory.

    • #105094
      scottie
      Participant

      The context has not changed any meaning.
      Here is what he went on further to say in the same lecture

      quote :

      Another aspect of the new philosophy of biology concerns the role of laws. Laws give way to concepts in Darwinism. In the physical sciences, as a rule, theories are based on laws; for example, the laws of motion led to the theory of gravitation. In evolutionary biology, however theories are largely based on concepts such as competition, female choice, selection, succession and dominance. These biological concepts, and the theories based on them, cannot be reduced to the laws and theories of the physical sciences

      my emphasis.

      No context change here at all.
      Ernst Mayr was simply being honest and indeed proud of it.

      Evolutionary theory is not a physical science it is a philosophy that is being promoted as a physical science.

    • #105095
      scottie
      Participant

      BDDVM

      You posted

      quote :

      I simply don’t aggree that your designer is beyond the reach of science.

      Ok let’s put that statement to the test

      Craig Venter and his team made headlines when they announced their success in transforming and existing cell into a cell with as he put it “with no biological anscester”

      He published an account of what his team accomplished in the Science Express portion of the journal Science. Here is an excerpt from the 12-page report.

      quote :

      pSynthetic genome assembly strategy
      The designed cassettes were generally 1,080 bp with 80-bp overlaps to adjacent cassettes. They were all produced by assembly of chemically synthesized oligonucleotides by Blue Heron; Bothell, Washington. Each cassette was individually synthesized and sequence-verified by the manufacturer.

      They made this long DNA molecule by putting together smaller segments of commercially available DNA which they purchased from Blue Heron. They purchased pieces that were about 1,000 base pairs long and joined ten of them together to form pieces that were about 10,000 base pairs long. They took ten of these 10,000 base pair pieces and joined them together to form pieces about 100,000 base pairs long. Finally, they joined eleven of these 100,000 base pair pieces together to form the complete molecule.

      In other words they designed and built a new genome and inserted this genome into the cell of another bacterium and it booted up.

      As he says

      quote :

      It took 15 years to get to this proof-of-concept experiment. And it is just that: proof that it is possible to use a computer and four chemical bases to create a cell with no biological ancestor. Of course, we began by modifying an existing genome. Where else to start?

      Now take any number of biologists and examine that cell. Make sure they have no information about how that cell came about. We know that it was clearly designed and built(or at least an important part of it was).

      Now just for clarity here is your statement again

      quote :

      I simply don’t aggree that your designer is beyond the reach of science.

      So please explain to me but more importantly to this forum, how these biologists by only using the tools of science can determine who the designer and creator of this new species is.

      If science can do that, then you should have no problem demonstrating it.

      Please prove me wrong.

    • #105098
      BDDVM
      Participant

      Sounds like Craig Venter was the designer in this case. I’m pretty sure you can’t extrapolate that very far. Craig Ventor is human, he was engaged in a scientific exploration, and I doubt that he has created any other life. (Being a scientist he wouldn’t keep it a secret.)
      Now back to your designer. WHO? WHAT? WHEN? WHERE? hell I am even curious about WHY? Inquiring minds want to know.
      By the way, if your apponant in an arguement gets tired, annoyed,exasperated and decides argueing with you is pointless, it doesn’t mean you have won the arguement. This is a common misconception among crackpots. Crackpots believe that when people politely nod and smile that they are aggreeing with the ranting. It just means that they know a crackpot when they see one and know that it can be dangerous to provoke the delusional. Don’t be a crackpot.

    • #105101
      scottie
      Participant
      quote :

      Sounds like Craig Venter was the designer in this case. I’m pretty sure you can’t extrapolate that very far.

      No NO it doesn’t sound like Craig Venter. It was Craig Venter and his team.

      And how do we know that Venter is the designer?
      Because he has provided an historical record, or has that simple point escaped your notice.
      Without that record we would not know who created it.

      We would not know by examining the cell itself with all the science at our disposal.

      As I have said before and repeatedly, neither I nor any other person could tell who created the cell without some form of authentic historical record, any more than could you tell who designed and made this cell without an historical record to accompany it.

      Surely even you with all your intelligence can understand that, can’t you?

      As for me, well I am just a crackpot aren’t I, so how could I possibly explain such simple concepts to you. 🙂

    • #105102
      BDDVM
      Participant

      I’m having trouble seeing what this experiment says about your designer.
      I recall you were at one time hung up on the idea that creating a new species was not possible. Even though it’s just a bacteria it is a new species, lab created. Just like the lizards.Two proofs of concept.
      It seems your designer hasn’t been doing anything metaphysical, just physical and well within the pervue of science.
      Sooooooo, once more Please describe your theoretical designer.
      If you evade this question once more I will give up on you and you will no doubt conclude (incorrectly) that you have won this arguement.

    • #105111
      scottie
      Participant

      Well there you go, rambling again. (bad sign) 🙂

      However let’s try and unravel your confusion.

      quote :

      I recall you were at one time hung up on the idea that creating a new species was not possible. Even though it’s just a bacteria it is a new species, lab created. Just like the lizards.Two proofs of concept.

      You really must not rely on your powers of recall, a very uncertain process. Go and read my posts again. It really isn’t that difficult, it is in English.

      quote :

      It seems your designer hasn’t been doing anything metaphysical, just physical and well within the pervue of science.

      It does seem that you have some difficulty with language. I need to take that into account in future. Very remiss of me, please accept my apologies.

      Where have I stated or even relied on anything metaphysical?
      In fact I have been arguing that the metaphysical is within your argumentation and therefore not physical science.

      quote :

      If you evade this question once more I will give up on you and you will no doubt conclude (incorrectly) that you have won this arguement

      Oh come come, I don’t need to conclude anything. You reveal it all for yourself far better than I could ever conclude.

      I will of course try and educate if you wish to continue. Patience is a virtue I have tried to develop over many years now, so don’t worry you won’t be in any danger of trying my patience, honest. 🙂

    • #105121
      freerob
      Participant
      quote scottie:

      There are a reducing number of biologists who still subscribe to the Darwinian process of random mutations.
      The main protagonists are notably Dawkins and Coyne who seem more interested in promoting their religious views rather than science.

      Please back up this absurd statement.

      Also, I take issue with your consistent mischaracterizations of what the literature, you yourself have linked in this thread, actually say.

      quote scottie:

      IF you have then you will know the answer to the question raised. However for the sake of clarity in case you have not fully absorbed the information I have presented.
      Allow me to quote directly from his (Shapiro’s)paper that incidentally has referenced some 56 other papers and articles in support of his presentation.
      Here is the paper again
      http://shapiro.bsd.uchicago.edu/21st_Ce … _Evol.html

      Shapiro could reference 56 or 560,000,000,000 papers. So what? This is from a lecture at a conference, is speculative, is NOT a peer reviewed scientific work. On top of this blatant appeal to authority, you (and other ID’ers) have totally overstated what Shapiro is saying in this document, which Shapiro himself is overstating. There is nothing earth shattering in the actual science he is referencing in this document.

      It’s a common tactic for creationists/intelligent design proponents to latch on to this particular document as if it totally disproves random mutation in favor of design claims. I back that statement up by simply pointing out that if search for Shapiro’s "third way" concept you find it plastered all over many psuedoscientific ID websites.

      quote scottie:

      Among such ones as Carl Woese and many many others there is Eugene Koonin of the National Center for Biotechnology Information, National Library of Medicine, and National Institutes of Health
      Koonin is widely regarded and is certainly at the center of the scientific establishment.
      In 2007 he presented a paper which is online here
      http://www.biology-direct.com/content/2/1/21

      It is entitled
      “The Biological Big Bang model for the major transitions in evolution.”
      May I urge you to read it please and not continue to be taken in by this myth of common decent.
      Only the priesthood of Darwinian doctrine continue with this myth.

      You have terribly mischaracterized this paper. In no way does this work refute common ancestry. It’s an attempt to reestablish the shape of the "tree of life", or even redefine it in other terms, to match the observational data. NOWHERE in the paper does the author even remotely suggest throwing out the idea of common ancestry.

      This Biological Big Bang argument in no way supports design claims. The peer reviewers, however, saw the potential for this work to be misinterpreted (intentionally or otherwise).

      Allow me to quote:

      quote :

      Reviewer 1: William Martin (University of Duesseldorf) “Abstract: “In each major class of biological objects, the principal types emerge “ready-made”, and intermediate grades cannot be identified.” Ouch, that will be up on ID websites faster than one can bat an eye.

      Your design claims are not science. Wish as though you might, they just aren’t. Design infers a designer. You admit science can’t find the designer. Therefore design claims are not science. Stop claiming they are.

      You also repeatedly allude to "Darwinists" and try repeatedly to make the claim that Darwinian evolution is a religion. This a tired old debate tactic of the Creationist/Intelligent Design community. It’s a way to try to equate the two (religion and the study of evolution by natural processes) even though are clearly not the same thing.

      Evolution is not a religion. Your evidence that it is a religion is the zeal and conviction with which it is pursued. This logic could be applied to ANY activity, for example quilting or coin collecting. Calling evolution a religion makes religion pretty much meaningless.

      The fact is, people of diverse cultural backgrounds and religious affiliations believe in evolution, yet not one of them, if asked, would identify their religion as evolution. If evolution is a religion, it is the only religion that is rejected by all its members.

      About your design claims:
      1) There is no "theory of design" in biology because design can’t be defined in the normal sense without also defining an agent and purpose. A theory of design must address agent and purpose or it is not about design. You admit that you do not define the agent and purpose. Therefore, even if you could somehow prove design, it wouldn’t be about design in the usual sense at all.
      2) Nowhere in the scientific literature is any design theory validated.
      3) The design claim is useless and unscientific, it has not generated any predictions and no scientific work has come from it.

      scottie, you can go on linking scientific works and mischaracterizing until your heart’s content but you’d still be wrong WRONG wrong. All throughout this thread you’ve made this argument from incredulity about design. The problem with your arguments is that they rely on "disproving" evolution instead of proving positive your own claims. You appear to be trying to sneak in the god of the gaps whether you admit or not.

    • #105122
      freerob
      Participant
      quote scottie:

      JackBean

      quote :

      Darwin introduced historicity into science. Evolutionary biology, in contrast with physics and chemistry, is a historical science – the evolutionist attempts to explain events and processes that have already taken place. Laws and experiments are inappropriate techniques for the explication of such events and processes. Instead one constructs a historical narrative, consisting of a tentative reconstruction of the particular scenario that led to the events one is trying to explain.
      The discovery of natural selection, by Darwin and Alfred Russel Wallace, must itself be counted as an extraordinary philosophical advance.

      What I wrote (the above)in my last post is a direct quote from Ernst Mayr himself in his lecture of 1999
      You will find that lecture here
      http://www.biologie.uni-hamburg.de/b-on … luence.htm

      One of the founding fathers of the modern synthesis proudly hails Darwinism as a philosophy.
      You are now taking on Ernst Mayr, well good for you.

      This is an absurd attempt to discount Darwinian evolution by misconstruing Mayr. Shame on you scottie. Shame.

      The effects of Darwin’s ideas on Philosophy and the founding of the well regarded science of Philosophy of Biology is clearly the sentiment of Mayr’s article. Not writing off Darwinian evolution as something less than scientific or as a something akin to religion.

      Mayr is giving praise to Darwin’s theories not solely as philosophical, but in addition to it’s merit as scientific FACT. Huge difference when you compare it to what you are inferring he meant scottie.

      Further down in Mayr’s article:

      quote :

      Let me now try to summarize my major findings. No educated person any longer questions the validity of the so-called theory of evolution, which we now know to be a simple fact. Likewise, most of Darwin’s particular theses have been fully confirmed, such as that of common descent, the gradualism of evolution, and his explanatory theory of natural selection.

      "No educated person any longer questions the validity of the so-called theory of evolution, which we now know to be a simple fact." Sounds a heck of a lot different than what you wrote in your post right above the one I’m criticizing:

      quote scottie:

      “All you have to do is recognise that natural selection is a philosophical concept. No different from the philosophical concepts of other religions.”

      Darwinian evolution is not a religion. Did you just not understand Mayr, or were trying to intentionally misconstrue him? Either way your point is invalid and wrong.

    • #105139
      LeoPol
      Participant

      Darwin created the theory of the origin of new species from the former by means of natural selection. The theory of evolution – "from simple replicators to the crown of evolutionary selection", he did not create, and just trying to adjust to his theory of the origin of species.

      The theory of evolution before Darwin came up as a "whipping boy", embed it in biology and used to criticize the science of being a missionary.

      Darwin’s theory works seamlessly with the theory of Devolution from the initial complex engineering design to dead-end species.
      http://translate.google.com/translate?h … ro.name%2F

    • #105173
      scottie
      Participant

      Response to freerob

      Sorry for the delay in responding but I have been doing other things and have only just got back to this forum.

      Now you raise a lot of questions for me to deal with so if I may I deal with each one in the order you raised them.

      First

      my statement
      "There are a reducing number of biologists who still subscribe to the Darwinian process of random mutations.
      The main protagonists are notably Dawkins and Coyne who seem more interested in promoting their religious views rather than science.”

      quote :

      Please back up this absurd statement.

      When you put out a challenge like this please be certain you know what you are talking about.

      Let me start backing up my statement with the actual names of Scientists who have publicly put their names forward as ones who refute the Darwinian process of natural selection acting upon random mutations

      Philip Skell Emeritus, Evan Pugh Prof. of Chemistry, Pennsylvania State University Member of the National Academy of Sciences
      Lyle H. Jensen Professor Emeritus, Dept. of Biological Structure & Dept. of Biochemistry University of Washington, Fellow AAAS
      Maciej Giertych Full Professor, Institute of Dendrology Polish Academy of Sciences
      Lev Beloussov Prof. of Embryology, Honorary Prof., Moscow State University Member, Russian Academy of Natural Sciences
      Eugene Buff Ph.D. Genetics Institute of Developmental Biology, Russian Academy of Sciences
      Emil Palecek Prof. of Molecular Biology, Masaryk University; Leading Scientist Inst. of Biophysics, Academy of Sci., Czech Republic
      K. Mosto Onuoha Shell Professor of Geology & Deputy Vice-Chancellor, Univ. of Nigeria Fellow, Nigerian Academy of Science
      Ferenc Jeszenszky Former Head of the Center of Research Groups Hungarian Academy of Sciences
      M.M. Ninan Former President Hindustan Academy of Science, Bangalore University (India)
      Denis Fesenko Junior Research Fellow, Engelhardt Institute of Molecular Biology Russian Academy of Sciences (Russia)
      Sergey I. Vdovenko Senior Research Assistant, Department of Fine Organic Synthesis Institute of Bioorganic Chemistry and Petrochemistry
      Ukrainian National Academy of Sciences (Ukraine)
      Henry Schaefer Director, Center for Computational Quantum Chemistry University of Georgia
      Paul Ashby Ph.D. Chemistry Harvard University
      Israel Hanukoglu Professor of Biochemistry and Molecular Biology Chairman The College of Judea and Samaria (Israel)
      Alan Linton Emeritus Professor of Bacteriology University of Bristol (UK)
      Dean Kenyon Emeritus Professor of Biology San Francisco State University
      David W. Forslund Ph.D. Astrophysics, Princeton University Fellow of American Physical Society
      Robert W. Bass Ph.D. Mathematics (also: Rhodes Scholar; Post-Doc at Princeton) Johns Hopkins University
      John Hey Associate Clinical Prof. (also: Fellow, American Geriatrics Society) Dept. of Family Medicine, Univ. of Mississippi
      Daniel W. Heinze Ph.D. Geophysics (also: Post-Doc Fellow, Carnegie Inst. of Washington) Texas A&M University
      Richard Anderson Assistant Professor of Environmental Science and Policy Duke University
      David Chapman Senior Scientist Woods Hole Oceanographic Institution
      Giuseppe Sermonti Professor of Genetics, Ret. (Editor, Rivista di Biologia/Biology Forum) University of Perugia (Italy)
      Stanley Salthe Emeritus Professor Biological Sciences Brooklyn College of the City University of New York
      Marcos N. Eberlin Professor, The State University of Campinas (Brazil) Member, Brazilian Academy of Science

      Now I am going to pause here, as it is only just a start, and ask you to match my list of non-Darwinists with a comparable list of Darwinists.

      For every name you put forward I will match it.

      Now are you prepared to go toe to toe with me with “this absurd statement” of mine.”

      I will deal with the rest of your comments but let’s first get this one out of the way.

    • #105177
      canalon
      Participant

      Nice appeal to authority.
      With some dead physicists and other people completely unrelated science. Is that supposed to impress anyone? Is a list of 20-something scientists demonstrating anything else than those 20-something people had view that dissent with the majority.
      How do that prove that a reducing number of scientist believe something?

    • #105183
      scottie
      Participant

      canalon

      I said that was a start, you really need to read what I am actually writing.
      How far do you wish me to go and more importantly will you be able to match me name for name.
      My list was not an appeal to authority but simply to respond to freerob’s challenge to support my previous statement.

      How else can I do that without naming names. I naturally assumed that to be a fairly basic requirement.

      By the way those I have named were not dead when they went public, some though may have died since. Life does have that unfortunate quality.

      Also as far as proof goes, just one or two of those who have changed from Darwinian to non Darwinian
      is sufficient to prove my point. —— However I am not relying on just a few.

      We can take this as far as you wish.

      I do understand however that your need to go for any little opening you can spot since the big gates have closed in on you.

    • #105184
      canalon
      Participant

      No you have not answered my question. I doubt you ever will.
      As for your list the kind of data would be rather like polls telling me what percentage of scientists (I’d rather have biologist as the other are not very likely to be more than laymen in the field) support which side of the discussion. if possible with size of sample, origin and method of sampling. You know data, not anecdotes (which is exactly what a list of name is).
      And since you claim a reducing number of scientists, please provide at least 2 data points (the more the merrier) to support your assertion.

    • #105185
      canalon
      Participant

      Oh and define scientist.

      Should I list my former students (3rd year Biology major), they know probably a lot more on the subject that some random chemists and mathematicians. Or all my fellow labmates?

    • #105186
      scottie
      Participant

      How many biologists would you like me to name?
      How many can you name?
      I notice you have learnt a salutary lesson not to engage in facts but just rely on rhetoric.

      So how many would you like me to name.

    • #105187
      scottie
      Participant

      Here are some more.

      Jiøí Vácha Professor Emeritus of Pathological Physiology Institute of Pathophysiology, Masaryk University (Czech Republic)
      John S. Roden Associate Professor of Biology Southern Oregon University
      Donald W. Russell Adjunct Assistant Clinical Professor University of North Carolina School of Medicine
      Geoff Barnard Senior Research Scientist, Department of Veterinary Medicine University of Cambridge (UK)
      Olivia Torres Professor-Researcher (Human Genetics) Autonomous University of Guadalajara (Mexico)
      Donald A. Kangas Professor of Biology Truman State University
      Dennis M. Sullivan Professor of Biology and Bioethics Cedarville University
      Robert D. Orr Professor of Family Medicine University of Vermont College of Medicine
      Laverne Miller Clinical Associate Professor of Family Medicine Medical College of Ohio
      S. Thomas Abraham Assistant Professor of Pharmacology & Toxicology Campbell University School of Pharmacy
      Professor of Anesthesiology Texas A&M Univ. Syst. Health Science Center
      Donald F. Smee Research Professor (Microbiology) Utah State University
      Colin R. Reeves Professor of Operational Research (Ph.D. Evolutionary Algorithms) Coventry University (UK)
      Eugene K. Balon University Professor Emeritus, Department of Integrative
      Biology University of Guelph
      Chrystal L. Ho Pao Assistant Professor of Biology (Ph.D. Molecular Genetics,
      Harvard U.) Trinity International University
      Joel Brind Professor of Biology Baruch College, City University of New York
      Jan Peter Bengtson Associate Professor (M.D., Ph.D. Intensive Care Medicine) University of Gothenburg (Sweden)
      Timothy A. Mixon Assistant Professor of Medicine Texas A&M University
      Ivan M. Lang Ph.D. Physiology and Biophysics Temple University
      John G. Hoey Ph.D. Molecular and Cellular Biology City University of New York Graduate School
      Theodore J. Siek Ph.D. Biochemistry Oregon State University
      Christian M. Loch Ph.D. Biochemistry and Molecular Genetics University of Virginia
      Charles A. Signorino Ph.D. Organic Chemistry University of Pennsylvania
      Luke Randall Ph.D. Molecular Microbiology University of London (UK)
      Jan Frederic Dudt Associate Professor of Biology Grove City College
      Eduardo Sahagun Professor of Botany Autonomous University of Guadalajara (Mexico)
      Mark A. Chambers Ph.D. Virology University of Cambridge (UK)
      Daniel Howell Ph.D. Biochemistry Virginia Tech
      Jonathan D. Eisenback Professor of Plant Pathology Dept. of Plant Pathology and Weed Science Virginia Tech
      Eduardo Arroyo Professor of Forensics (Ph.D. Biology) Complutense University (Spain)
      Peter Silley Ph.D. Microbial Biochemistry University of Newcastle upon Tyne
      E. Norbert Smith Ph.D. Zoology Texas Tech University
      Peter C. Iwen Professor of Pathology and Microbiology University of Nebraska Medical Center
      Luman R. Wing Associate Professor of Biology Azusa Pacific University
      Wesley M. Taylor Former Chairman of the Division of Primate Medicine & Surgery New England Regional Primate Research Center, Harvard Medical School
      Wayne Linn Professor Emeritus of Biology Southern Oregon University
      Gregory D. Bossart Director and Head of Pathology Harbor Branch Oceanographic Institution

      Do you wish me to carry on, or are you going to try and move the goal posts?

    • #105188
      freerob
      Participant
      quote scottie:

      Now I am going to pause here, as it is only just a start, and ask you to match my list of non-Darwinists with a comparable list of Darwinists.

      For every name you put forward I will match it.

      Now are you prepared to go toe to toe with me with “this absurd statement” of mine.”

      Obviously you are unaware of "project Steve". http://ncse.com/taking-action/project-steve

      quote :

      NCSE’s “Project Steve” is a tongue-in-cheek parody of a long-standing creationist tradition of amassing lists of “scientists who doubt evolution” or “scientists who dissent from Darwinism.”

      Today the list of scientists who DO NOT doubt Darwin’s theory AND have the first name of Steve sits at well over 1100(one-thousand-one-hundred). Considering only about 1% of scientists are named Steve, I’d say your attempt to show Evolution as a theory in crisis with a list of "dissenters" has been shown to be absurd.

      Each one of those on that list of "Steves" had to voluntarily sign up to be on it. They all had to sign and support the following statement:

      quote :

      The statement:

      Evolution is a vital, well-supported, unifying principle of the biological sciences, and the scientific evidence is overwhelmingly in favor of the idea that all living things share a common ancestry. Although there are legitimate debates about the patterns and processes of evolution, there is no serious scientific doubt that evolution occurred or that natural selection is a major mechanism in its occurrence. It is scientifically inappropriate and pedagogically irresponsible for creationist pseudoscience, including but not limited to “intelligent design,” to be introduced into the science curricula of our nation’s public schools.

      How many Steves were on your list? More than 1100? 😆

      Edit to add insult to injury:

      quote scottie:

      When you put out a challenge like this please be certain you know what you are talking about.

      Back at ya! 😀

      freerob

    • #105189
      freerob
      Participant

      The list scottie is copying names from is most likely the one found at http://www.dissentfromdarwin.org/index.php ,a website belonging to The Discovery Institute, now calling itself the Center For Science and Culture. The leading "Intelligent Design" advocacy group in the U.S. He should have cited his source but didn’t. I noticed quite a few of the names on both lists (the website’s and scottie’s).

      If that is the reference source for scottie’s list of scientists it should be noted that there are many serious criticisms of how it was gathered. Mainly through a petition called "A Scientific Dissent From Darwinism". Since the list was published, some who have signed on to it have dissented from the petition itself. Claims of being mislead into signing on to it and of misrepresentations were reported.

      Only 80 of the original 700 signing the petition were biologists to answer canalon’s question since scottie tried to skate past it (if indeed this is his source, he didn’t cite a source).

      All are welcome to review the wiki-article on "A Scientific Dissent From Darwinism".

      quote :

      In their 2010 book Biology and Ideology from Descartes to Dawkins, science and religion scholar Denis Alexander and historian of science Ronald L. Numbers tied the fate of the Dissent to that of the wider intelligent design movement:

      After more than a decade of effort the Discovery Institute proudly announced in 2007 that it had got some 700 doctoral-level scientists and engineers to sign “A Scientific Dissent from Darwinism.” Though the number may strike some observers as rather large, it represented less than 0.023 percent of the world’s scientists. On the scientific front of the much ballyhooed “Evolution Wars”, the Darwinists were winning handily. The ideological struggle between (methodological) naturalism and supernaturalism continued largely in the fantasies of the faithful and the hyperbole of the press.

      freerob

    • #105190
      scottie
      Participant

      well done Freerob
      At last some one is actually doing some homework.

      As I said before and will say again, can you match name for name. Whatever the source at least these people have actually had the temerity to put their names out in public.
      Do you see names such as Shapiro, or Koonin,( I will deal with your comment regarding him shortly) or Woese or any other of the evolutionary scientists who refute Darwinism. Of course not.

      And why not. –because they don’t wish to be associated with ID or any other interpretation. They will critique from within but not commit the gross sin of siding with the opposition.
      This is all about the "them and us" syndrome and nothing to do with facts. I will comment further on this list.

      However let me move on for the moment to Shapiro

      quote :

      Shapiro could reference 56 or 560,000,000,000 papers. So what? This is from a lecture at a conference, is speculative, is NOT a peer reviewed scientific work. On top of this blatant appeal to authority, you (and other ID’ers) have totally overstated what Shapiro is saying in this document, which Shapiro himself is overstating. There is nothing earth shattering in the actual science he is referencing in this document.

      Nice little bit of rhetoric but please tell me was “Origin of Species” ever peer-reviewed before publication like all good scientific papers should, or as you put it was just speculative? 🙂

      However what part of Shapiro’s “essays” if you like, are speculative and overstated.
      Please enlighten me.
      Also can you cite any peer-reviewed paper that actually contradicts what he states as observed facts.

      By the way I am not an advocate of Shapiro’s views per se, but simply quote him as an example of the divide between Darwinists themselves. He clearly does not support Darwinian theory.

      quote :

      It’s a common tactic for creationists/intelligent design proponents to latch on to this particular document as if it totally disproves random mutation in favor of design claims. I back that statement up by simply pointing out that if search for Shapiro’s “third way” concept you find it plastered all over many psuedoscientific ID websites

      .

      It may or may not be a common tactic for creationists/intelligent design proponents, but since I am neither, one or the other, your accusation lacks any power with me. Please read my previous posts.

      quote :

      Evolution is not a religion. Your evidence that it is a religion is the zeal and conviction with which it is pursued. This logic could be applied to ANY activity, for example quilting or coin collecting. Calling evolution a religion makes religion pretty much meaningless.

      Religions are belief systems. They do not rely on factual evidence to support their beliefs. That is why they are beliefs or points of view!!! They generally rely on sacred dogmas.

      Now Is Darwinian theory simply a dogma ?
      Well let’s see
      Species arrive by common decent through natural selection sifting out random mutations. In other words random mutations produce a phenotypic change in an existing species and then that change remains, or is discarded by natural selection.

      Now lets have the evidence please in a macro evolutionary sense.
      No unsupported statements of any materialist philosophy counts as evidence as you well know.

      So let me turn to Ernst Mayr the root of so much of my shame 🙂

      quote :

      Mayr is giving praise to Darwin’s theories not solely as philosophical, but in addition to it’s merit as scientific FACT. Huge difference when you compare it to what you are inferring he meant scottie.

      So according to you Darwinian theory is a scientific fact. Yes?

      Now these are the words of Ernst Mayr himself. I am not editing anything or taking him out of context. He simply argued his corner very rigorously.

      quote :

      The discovery of natural selection, by Darwin and Alfred Russel Wallace, must itself be counted as an extraordinary philosophical advance

      So if the theory is a fact why does it need a supporting philosophy?
      After all, other scientific facts don’t have,or indeed need, supporting philosophies.
      Newton’s Laws on gravity, Kepler’s Laws of motion, Chargaff’s rule of GC% content etc etc.

      The reason is simple, it is a philosophy. Mind you Mayr also describes it as a historical science.
      Now that puts it on a par with Archaeology, and we all know how exact a science archaeology is don’t we?

      If you were honest enough to acknowledge that, at best this theory is a material interpretation of what is believed to have happened then there is no problem, except of course for you it is a problem, because it put this on the same level as other interpretations.
      So a dictat is issued – how does Mayr put it- and you so rightly quote him

      quote :

      No educated person any longer questions the validity of the so-called theory of evolution, which we now know to be a simple fact.

      So anyone who questions Darwinian Theory is not an educated person according to Ernst Mayr and you as one of his obedient acolytes simply parrots the same dictat as though it had some force.

      That means that all the PHD scientists (I have already provided you with a very very small starting list of these ) who do not hold with the theory, are part of the uneducated masses.

      Oh dearie me 🙂 ( It’s an english expression)

      The Darwinian doctrine is a sacred doctrine that only the educated can comprehend.
      Hmm!!! sounds very much like the principle driving force that was behind the Spanish inquisition.

      Look if you don’t like being referred to as a religionist then don’t behave like a fundamentalist in religion.

      I will take up “

      quote :

      About your design claims

      ” in my next post.

    • #105193
      canalon
      Participant

      Scottie You said you want science. A list of name is just a butterfly collection it does not say anything on the larger population, the changes over time of the acceptance of the idea or anything interesting. This not science, this is anecdote.

      You claimed that there is a reducing number of scientist backing up evolution, could you provide facts baking up your claim?

      You claim that life as we see it is evidence for design. If this is true, and scince design imply action by an outer agent, what would this agent be? and how did it came to be? I remind you that you were the one that first called Occam’s razor in deciding what hypothesis should be accepted. Is an infinitely recursive loop simpler to accept than "spontaneous order from chaos"?

    • #105197
      scottie
      Participant

      canalon
      I will respond to your post but if I may I would first like to continue with freerob’s rather lengthy series of questions.

      Promise I will return to you.

      freerob
      Now I will take up “About your design claims” i

      quote :

      About your design claims:
      1) There is no “theory of design” in biology because design can’t be defined in the normal sense without also defining an agent and purpose. A theory of design must address agent and purpose or it is not about design. You admit that you do not define the agent and purpose. Therefore, even if you could somehow prove design, it wouldn’t be about design in the usual sense at all.
      2) Nowhere in the scientific literature is any design theory validated.
      3) The design claim is useless and unscientific, it has not generated any predictions and no scientific work has come from it.

      Point 1
      As regards the theory of design. Please get your facts straight. Do some research on for instance the theory of C K design.

      However does design feature in biology?

      This is what George V. Lauder of Harvard University has to say on the subject
      http://www.people.fas.harvard.edu/~glau … heoBio.pdf

      quote :

      1. Introduction
      The problem of biological design is one of the oldest topics in biology. It has been clear, at least from the time of Aristotle, that organisms possess a “unity of plan” or underlying commonality of structure, and that the function of biological features bears some relationship to their form. E. S. Russell in his classic book (1916) has interpreted the history of morphology as an attempt to understand the relationship between form and function.
      The concepts of commonality of structure and functional design play
      prominent roles in modern evolutionary morphology.

      So please tell has any scientist refuted this statement?

      In fact so profuse is the recognition that some have sought to try to remove the word design from scientific literature.

      Here is what Andrew Moore Editor-in-Chief of online library of Wiley has suggested. Have a read here.
      http://onlinelibrary.wiley.com/doi/10.1 … 90011/full
      Also see http://www.synbioworld.org/

      quote :

      2 ) Nowhere in the scientific literature is any design theory validated.

      What do you mean by this statement. There is plenty of literature teaching design theory. Perhaps you could be more precise. Are you saying that design is not a scientific concept?

      quote :

      3) The design claim is useless and unscientific, it has not generated any predictions and no scientific work has come from it.

      Does Darwinian theory generate any predictions? If it does then it cannot be random or undirected.
      So according to your logic then Darwinian theory is also as you put it useless and unscientific.

      You really need to think more carefully before engaging in your rather rash rhetoric.

      Now design meets even your requirements.

      Lets take the digestive system of say, yourself.

      From teeth to anus there is purpose is there not.
      You know the food intake goes into your stomach, gets digested, produces the necessary fuel to power the cellular processes to keep you alive.
      The waste parts of the food that your body cannot use you discharge through your anus.

      Now does this tract have purpose.
      Answer – Yes, fundamentally to keep you alive. There are some side issues like waste discharge. It also allows you to blow hot air from time to time.

      Is there a process?
      Answer – Yes, you can see that process depicted in any digestive tract diagram.

      But Darwinian theory has no purpose – Right?
      It is undirected — Right?

      So for this tract to arrive by a Darwinian process some undirected and purposeless mutation(s) would have to have taken place in the genome — Right?

      Lets ignore the fact that most mutations lose information instead of gaining information.

      Where does this mutation process start? Is it at the teeth or at the anus?
      Or does it start with an already existing digestive system?

      But that means that the already existing digestive system must also have mutated from a previous digestive system.

      But wait a minute don’t all these previous systems have purpose, and function and direction, all the attributes of design.
      But common decent is a major plank in Darwinian theory. Yes?

      So really it is design all the way back right to the very beginning is it not?

      Now could you please explain to me, an obviously uneducated person, where purposeless and undirected processes fits into this scenario.

      Now I don’t want you blowing any hot air at me, just give me the FACTS – please

      I need to know.

    • #105201
      canalon
      Participant

      Scottie,

      Would you be an engineer, per chance?
      This is unrelated to the discussion, and will not be discussed further, but I am curious…

    • #105202
      freerob
      Participant
      quote scottie:

      However does design feature in biology?

      This is what George V. Lauder of Harvard University has to say on the subject
      http://www.people.fas.harvard.edu/~glau … heoBio.pdf

      quote :

      1. Introduction
      The problem of biological design is one of the oldest topics in biology. It has been clear, at least from the time of Aristotle, that organisms possess a “unity of plan” or underlying commonality of structure, and that the function of biological features bears some relationship to their form. E. S. Russell in his classic book (1916) has interpreted the history of morphology as an attempt to understand the relationship between form and function.
      The concepts of commonality of structure and functional design play
      prominent roles in modern evolutionary morphology.

      So please tell has any scientist refuted this statement?

      There is no issue with the use of the word "design" in the above cited paper because the author clearly points out his definition of "design" as a biological structure relative to it’s function and the "designer" as adaptation through natural selection. In the introduction you quoted from, the author gives us his definition of design and designer. I probably wouldn’t use the word design to describe the result of an unguided process, however, as you point out, it’s common in the terminology. Not that the frequency of the use of the word design in any way gives it the meaning you wish it to have.

      My issue is with YOUR use of the word design. You imply design in a guided manner but do not define a designer. Please clearly state your design hypothesis, including your "designer".

      Using the author quoted above’s definitions, you arrive at Darwin’s theory. This is another example of you(scottie) attempting to misconstrue or mischaracterize what a cited example actually says. The article is actually really interesting if you read it. Does it refute natural selection in favor of a "design and designer"? Nope. That’s not what the paper discusses in any way, shape, or form.

      Was the Grand Canyon designed? It has form and function. I suppose you could say it was if you include geologic forces as the designer. However, design is probably not the best word choice, which brings me to the article by Andrew Moore that you cited. http://onlinelibrary.wiley.com/doi/10.1 … 90011/full

      I strongly agree with Moore here. I have heard others propose similar ideas and agreed to that as well. Anthropomorphic terminology is a problem, and is even evidenced by you yourself scottie. In articles you have linked, you imply such a meaning to words like design when a different meaning is what was intended by it’s author.

      I’m beginning to think there is a not a difference of opinion here in this thread so much as an attempt to lead a discussion astray by deception. The strategy you have used is this: The word design is used in an article and you ascribe an invocation of an agency, even though the author clearly did not. Or, if not an anthropomorphic misconception, you take a quote and attempted to twist it into a meaning it does not have in the broader context of the entire article, what is commonly called "quote mining". It’s a form of dishonesty. Also you use terms like "Darwinism" and "Darwinists" in an almost derogatory manner. That’s an example of trying to write off the scientific consensus as mere "group-think", and it’s wrong. That’s what ID proponents do when their arguments can’t pass the scientific test. Claim the consensus is dogmatic and intolerant to new ideas.

      I also want to address this nonsense:

      quote scottie:

      So if the theory is a fact why does it need a supporting philosophy?
      After all, other scientific facts don’t have,or indeed need, supporting philosophies.
      Newton’s Laws on gravity, Kepler’s Laws of motion, Chargaff’s rule of GC% content etc etc.

      How about:
      Philosophy of Chemistry
      Philosophy of Mathmatics
      Philosophy of Physics

      Yes, evolution is a FACT. Does it need a supporting philosophy? NO. What was stated by Mayr and others was that the unifying theory of biology, evolution by natural selection, opened the door for a Philosophy of Biology. It was as indeed as profound as Mayr stated in the article you linked.

      Where you get it wrong is in trying to put the cart before the horse. The science behind Darwin’s theory came before any philosophy could be built upon it. Not vice-versa as you attempt to assert. Additionally, the philosophy that arose from Darwin’s theories was/is not playing some "supportive" role in propping the theory up as you suggest. It’s how we deal with the implications of a new way of understanding the natural world around us and our role in it. Just the same as Philosophy works when applied to Chemistry or Physics or Mathematics.

      What is the following quote supposed to achieve?

      quote scottie:

      So anyone who questions Darwinian Theory is not an educated person according to Ernst Mayr and you as one of his obedient acolytes simply parrots the same dictat as though it had some force.

      That means that all the PHD scientists (I have already provided you with a very very small starting list of these ) who do not hold with the theory, are part of the uneducated masses.

      Oh dearie me ( It’s an english expression)

      The Darwinian doctrine is a sacred doctrine that only the educated can comprehend.
      Hmm!!! sounds very much like the principle driving force that was behind the Spanish inquisition.

      Look if you don’t like being referred to as a religionist then don’t behave like a fundamentalist in religion.

      Weren’t you repeatedly accusing others in this thread of using rhetoric? Hey pot, what color is that kettle again? 🙄

      You call me religionist because I’m someone who agrees with the scientific consensus and argues the merits of a theory with zeal eh? Ridiculous. Also that list of PHD’s you’ve mentioned again is a punchline more than it is a reason to take the ID movement seriously. You admit the list came from a Creationist/Intelligent design website. You claim you aren’t one of "them", but you use their propaganda on a legitimate biology forum?

      Also. Your abrasive, sarcastic, and passive aggressive tone really rubs me the wrong way. The floor is yours to spread some more fallacies draped in jargon and rhetoric I suppose.

    • #105210
      JackBean
      Participant
      quote canalon:

      Scottie,

      Would you be an engineer, per chance?
      This is unrelated to the discussion, and will not be discussed further, but I am curious…

      😆 😆

    • #105230
      scottie
      Participant

      Canalon

      To answer your question
      Yes I am an engineer. I am a retired Managing Director of a communications company. My main subject is communications engineering.

      May I ask you to please think about this and ask yourself if it is explainable. I am not looking to you to post any explanation, just to think about it.

      What is physically the difference between a living animal and the same animal at the moment of death.
      The corpse, remains under the same laws of physics and chemistry as the living animal, does it not?
      The same collection of molecules exist in the animal during the moments immediately before and after death.

      Yet after this transition, will you as a biologist think about genes as being regulated, or would you refer to normal chromosome functioning?.

      No molecules will be carrying signals and certainly there will be no structures that will recognise those signals.

      Coded information and communication in their biological sense, will have disappeared completely.

      If life is simply a material manifestation of arranged molecules, why is there this complete contrast between the living and the dead animal.
      Physically, they are still the same are they not?

      Now you are trying hard to explain that life is just a collection of molecules arranged, amazingly, not just by some functional design, but by of all things, randomly.

      Darwin privately envisioned life as starting from some quiet little pond full of the right molecules wherein life first got started.

      Scientific American in it’s September 2010 article entitled “Dust to Dust” page 58 describes the process of cell death

      quote :

      IN THE FIRST STAGE, soft tissue begins to decompose in a chain of events that starts with autolysis, or self-digestion. When breathing and circulation cease, cells are left without a supply of oxygen. The cells survive for a few minutes to a few days, but they can no longer pass wastes into the bloodstream. Carbon dioxide, one of the by-products of metabolism, is acidic, and as it accumulates, the acidity inside a cell increases, causing cell membranes to rupture. Single membranes surrounding organelles called lysosomes tend to dissolve first. The sacs contain digestive enzymes normally used by cells to break down organic molecules such as proteins. As these enzymes spill out, they begin digesting the cell from the inside out, eventually creating small blisters in and on internal tissues and organs and on the skin. The blister fluid, consisting of digested cell innards, is rich in nutrients. ( my emphasis)

      So here is all that is needed to start life off with. As Darwin envisioned a fluid rich in nutrients and we have that postulated “little pond”.

      What then do these nutrients have to do?

      Well it’s quite simple really.

      The nutrients separate themselves into cell walls and enzymes. But of course actually these enzymes naturally digest those very cell walls. (But never mind lets carry on)

      For some reason, lysosomes form to prevent that from happening.

      Then the cells start taking in carbon dioxide from surrounding fluid to release oxygen. And viola there we have it Life! 🙂

      Yet, you know as indeed I know that this does not happen, despite the conditions being so amenable.

      What I find hard to understand is:-
      What is it about this so obvious manifestation of evidence of some force operating beyond physics and chemistry, that you find so abhorrent to come to terms with.

      Whatever this life force is, science is simply unable to explain, and yet not only do you seem to refuse to acknowledge this fact that is staring out at everyone, but you so readily appear to accept the notion that somehow and quite miraculously a random collection of molecules has come together and produced a living organism that has purpose, function and behaves predictably.

      Is it not obvious that this life force whatever it may be, and clearly is quite apart from physics and chemistry, has to be present before life can manifest itself.

      If scientists would have some idea as to what this life force is then it could perhaps be explained, but as it is science cannot explain it.
      All we know with any confidence is where this life force comes from. You know it, I know it, every biologist knows it.
      It comes from another life.

      Scientists cannot even provide an agreed definition of what life is, let alone explain it.

      This whole controversy is not about science, it is about different philosophies or religious beliefs that are trying to deal this question.

      Ernst Mayr knew exactly what he was talking about when he described Darwin’s view as an extraordinary philosophic advance.

      So coming again to your repeated question, can I name the designer?,–
      No I cannot, because science cannot.
      Does not your own tag line go something like this “ Science is proof without certainty….”

      Yet you are trying to obtain a proof with certainty from me, which of course completes your tag line, rebutting creationists.

      All anyone can ever do is provide a philosophical view that will probably be different from yours.
      That of course will not be a scientific exchange, it will be a philosophical exchange.

      So please tell me what prevents you from acknowledging that the materialist viewpoint you clearly hold (correct me if I am misrepresenting you) cannot be proved scientifically.

      Ernst Mayr proudly acknowledged it as such.
      However he put himself on the pedestal that clearly demeans anyone, that has a different view, as uneducated. This sort of arrogance does indeed permeate discussions like this and it does come from all sides of the debate.

      Therefore it is not possible to enter into any rational discussion with that arrogant perspective as a controlling edict.

      And that, as I have said before, is not a road I will go down, simply because of the way these exchanges quickly degenerate into shrill name and cat calling.

      Now if you as a moderator would wish to start a thread on this subject with the strict rule that everyone’s views will be treated with respect, then I will happily have an input.
      This will also give some freeness of speech for any views to be aired without the posters of those views having to cope with the distaste of the emotional demeaning that keeps taking place.

    • #105231
      canalon
      Participant

      1- There is a theory that those doubting evolution are particularly common among engineers. No explanation, just correlation. It is inconsequential but funny, and indeed very often true. the good thing is that in spite of the general very poor understanding of biology (no, you are no exception), at least the argument with engineers are slightly more interesting that with the religious crowd.

      2- For your little story, decomposition of living things are usually not leading to new life, because even in the deadest corpse is teeming with life which is extremely adept at using all source of energy to its benefits. And very efficient at it too. So even if a new life form were to emerge, it would be at such a competitive disadvantage that it would disappear quickly. (Think throwing a toddler in a hungry tiger cage to compete for food….).

      3- You still have not answered my one simple question.

    • #105269
      scottie
      Participant
      quote :

      There is a theory that those doubting evolution are particularly common among engineers. No explanation, just correlation

      There is nothing theoretical about your comment.

      You see engineers have to live in the real world of physical laws. They have to design and make things. Therefore they are bound by laws that make their projects possible.
      They cannot philosophise or fantasize about matters, because philosophy and fantasy do not make things.

      quote :

      the good thing is that in spite of the general very poor understanding of biology (no, you are no exception),

      So that’s your best argument is it?
      What part of biology have I got wrong?

      quote :

      For your little story, decomposition of living things are usually not leading to new life, because even in the deadest corpse is teeming with life which is extremely adept at using all source of energy to its benefits.

      I am not referring what decomposition may lead to.
      Are you deliberately trying to miss-understand the point I was making?

      My point was to try and help you to think that life is not a physical/chemical process.
      Life uses physical and chemical processes and is something apart from them.

      Darwinian theory in effect states that life is just a physical/chemical process and my “little story” as you put it simply shows that that is not so.

      Even I, who only studied biology at college knows what Louis Pasteur proved.
      Do go back to your school notes and read all about his experiments.
      Or did you not learn that at school?.

      Life only come from another pre-existing life.(that’s what Pasteur demonstrated and to date it has not been refuted)

      Every biologist knows that, but those of a materialist philosophy then try to argue otherwise and as I have said before that number is reducing.

      Of course micro-organisms (other living organisms) do infect and feed off the dead corpse, but corpse is dead and you know it. The life that was controlling that now dead copse is no longer there. It has gone, vanished , vamoosed, disappeared.:)

      The biological processes in that corpse has wound down and no longer exists.

      Are you seriously arguing that the dead corpse is somehow alive or with the right physical conditions could be made alive again?
      Is that your contention?

      Come on surely even you can do better than that.
      I know, points you are unable to answer are somehow irrelevant, but only because you are not able to answer them.

      You may wish to argue by issuing dictacts. That what religions do, but that only enhances my contention.

      quote :

      You still have not answered my one simple question.

      Again, I have and you know it.
      You ask for a name as if that matters scientifically.
      You are trying to hide behind a philosophical point to advance your claimed “scientific” view.

      However have you even tried to describe how random, undirected processes can account for the functionality we observe in the cell?

      Other than, ofcourse stating by – dictact – that it does.

      That is your problem.
      You are stuck with a doctrine that you can’t explain, you cannot prove, so you have to rely on these dictacts.

      I have often asked priests and clergymen to explain the doctrine of the trinity. (you know how three persons can be one person).
      The answers is always the same.

      Well it is. It is a FACT. 🙂
      Now how is your method any different?

      I see no difference.
      But then I have no imagination, after all I only a humble engineer:)

    • #105270
      canalon
      Participant

      Thank you for your demonstartion of your ignorance and stupidity. That will be my last post in this thread.

      Just for your education, i will nevertheless that death is not what you think. When an organism dies, it does not mean that all cells instantaneously dies simultaneously. In fact, all cells will die, but some might take way longer time depending on their requirements in food and oxygen. So life is still active, but the general system is unable to perform the coordinated activities that were allowed the survival of the organism. In case of a human, that would entail respiration, blood circulation and so on. Some cells that are bad are storing energy and with high energy needs (as neurons) will die quickly when those functions cease. Other like some hair and skin cells with very low requirement will be able to keep going for weeks, in their own little corner.
      As an engineer you should think of it as a very complex machine with multiple independant subsystems where the central control dies. many of the subsystems will be able to carry (some of ) their functions automatically, but without order or significance. The machine itself is dead.

      As for your engineer explanation, we pretty much agree on the reason of the correlation (used to work on complex and designed system) but in my view you need to add arrogance and ignorance (of biology) to the mix to explain creationism. And you sir are are an arrogant fool. Learn about biology before you talk.

    • #105285
      kathreeds
      Participant

      Rapid advances in the study of genetics and molecular biology have produced additional insight into fundamental questions such as the origin of life on Earth. You should write a paper that provides an overview of Genetics engineering perspective

    • #105295
      scottie
      Participant

      canalon

      quote :

      As an engineer you should think of it as a very complex machine with multiple independant subsystems where the central control dies. many of the subsystems will be able to carry (some of ) their functions automatically, but without order or significance. The machine itself is dead.

      As for your engineer explanation, we pretty much agree on the reason of the correlation (used to work on complex and designed system) but in my view you need to add arrogance and ignorance (of biology) to the mix to explain creationism. And you sir are are an arrogant fool. Learn about biology before you talk.
      Patrick

      We are agreed then as you say the “machine” is dead.

      Now if you had actually read what I did write, you would have understood I was describing a winding down process
      I actually said

      quote :

      The biological processes in that corpse has wound down and no longer exists.

      To add to the information I could have said that individual cell death takes anywhere from some minutes to perhaps a couple of days as the lack of blood flow starves the cell of the energy needed to maintain operations and so on and so forth.

      However I assumed I was debating with a biologist who would have known these things.
      But there you go, in my arrogance, I deemed it unnecessary.

      However you do make a valid point

      quote :

      Learn about biology before you talk.

      Indeed I have spent the last three years learning, which is why I have the “arrogance” to debate with an obviously intelligent biologist, on his own turf.

      To demonstrate how much I have learned, not from my own research, but from those much more eminently qualified, I will take up kathreeds suggestion and present some of the latest research in genetics.

      I appreciate you will not be saying anymore on the matter but perhaps others may be interested in what is coming to light.

      I will of course support whatever I present with the necessary evidence. (as I have always done)
      kathreeds

      Thank you for your suggestion. A tremendous amount is being learned about cell functions.

      One of the major areas of research is in the field of epigenetics.

      The information is quite fascinating.

    • #105297
      scottie
      Participant

      Since Watson and Crick identified the structure of DNA and Marshall Nirenberg along with Hargobind Khorana and Robert Holley broke the code of it, a central dogma in molecular biology solidified.

      DNA codes RNA codes Protein.
      DNA being the carrier of genetic information in organisms.

      http://employees.csbsju.edu/hjakubowski … dogma.html

      In the 1990’s it became evident that this simple concept of DNA encoding protein is not what is actually happening.

      It became clear that the original length of DNA (the gene) is substantially altered before the protein encoding is accomplished.

      quote :

      RNA editing in plants, as in other organisms, challenges our traditional notions of genetic information transfer.

      http://www.ncbi.nlm.nih.gov/pubmed/8422976

      In my post of the 20th May I provided some information relating to the way a gene is modified before protein is manufactured.
      by scottie » Fri May 20, 2011 9:30 pm
      about14351-84.html

      My comment was

      quote :

      The original DNA gene is simply a very rough and incomplete information set that is required to produce the function it is required to. It has to be modified

      This means that the DNA genes, in some cases, do not determine the proper sequence of amino acids. The information provided by DNA messages is – in these cases -simply wrong, from the functional, biological point of view, and it has to be edited during a separate stage. As a result of this editing the original, primary molecular meaning of a given gene can be radically changed.

      If DNA is the main ruling agency of the body mechanisms, then any mutilation of the DNA molecule should be fatal and unrecoverable. In reality DNA can, and is constantly being repaired. Somehow the organism knows how to detect a change in the genetic message, and utilizes many different, complex procedures to repair different forms of mutation.

      This was in effect introducing the subject of epigenetics into the discussion

      You will find this site a useful introduction to the subject

      http://epigenome.eu/en/1,1,0

      I will take this a little further next.

    • #105298
      JackBean
      Participant

      so? How does that relate? 🙄

    • #105307
      JackBean
      Participant

      just a little joke 🙂
      http://xkcd.com/154/

    • #105318
      oldman
      Participant

      It seems to me that some of you have fallen into a classic creationist trap. You can tell by “Scottie`s” ever increasing length of arguments and his arrogance and his ”boys, if you can`t follow me, I will take it slow and easy” act. He`s showing off, obviously. He`s playing for an audience and that is really the tactics for creationists nowadays. Be strictly scientific, strictly unreligious and repeat as often as possible that the idea of evolution is really a belief system. I think it was obvious when “Scottie” stated that evolution is a fact, but only within species. To say that, you have a different motive than science. I hate to see these fake debates over and over again. I think they are harmful to forums like this and to science in general.

    • #105349
      scottie
      Participant

      oldman

      Thanks for the compliment.
      It’s nice to have it recognised that I am sticking strictly to science and being un-religious.
      I assumed that science is about just that.

      I will therefore continue with the science and continue to keep religion out of the discussion.

      So
      Is the DNA sequence the Master controller of the cell?

      We all begin life as a single cell containing an entire genome.
      As the cell divides the chromosomes are faithfully replicated so that each daughter cell receives the same genome (There are some exceptions to this. For example in the human immune system.)
      So how is it that the daughter cells then go down different pathways leading to different tissues in this process of differentiation?

      The offspring of one cell will eventually gain the ability to expand and contract as part of a muscle, while another will take on a rigid form with a specialized ability to transmit electrical signals etc etc.
      In the human genome there are about 200 different cell types..

      This instruction set (genome) apparently does not contain all the instructions needed for cell growth.
      These instructions are extra or above (epi) to the genome.

      Now there is also another factor worthy of consideration.

      The result of the Human Genome Project posed another problem.
      It was expected that the human genome would contain about one hundred thousand protein coding genes. Instead it turned out to be only about twenty odd thousand.

      This number is roughly about the same as a simple one millimeter long roundworm.

      Genes are therefore far from the whole story.

      Most of the human DNA (some 98.8%) does not code for proteins. The bulk of this non coding DNA was referred to as junk i.e. the evolutionary accumulation of meaningless genetic leftovers.

      However as more information has surfaced an intriguing picture is revealed.
      Non coding DNA accounts for only 10% of a one celled prokarote, only 32% in yeast, 75% in roundworms, 83% in insects, 91% in a pufferfish.
      The more complex the organism the greater is the amount of this “junk”.
      This is highlighted in this paper
      http://onlinelibrary.wiley.com/doi/10.1 … 4/abstract

      quote :

      We show by analysis of sequenced genomes that the relative amount of non-protein-coding sequence increases consistently with complexity. We also show that the distribution of introns in complex organisms is non-random.

      The above is a direct quote from the above abstract.

      So we have gone from “junk” to the primary measure of our evolutionary advance, as organisms have got more complex. 🙂

      So a reasonable question to ask would be.

      How does Darwinian theory of random mutations of the genome explain this 98.8% “junk” in the human genome and which incidentally is distinctly non-random?

      This is how cell biologist Lenny Moss reviews the situation in his book “ What Genes can’t do”

      Once upon a time it was believed that something called “genes” were integral units, that each specified a piece of a phenotype [that is, a trait], that the phenotype as a whole was the result of the sum of these units, and that evolutionary change was the result of new genes created by random mutation and differential survival.
      Once upon a time it was believed that the chromosomal location of genes was irrelevant, that DNA was the citadel of stability, that DNA which didn’t code for proteins was biological “junk,” and that coding DNA included, as it were, its own instructions for use.
      Once upon a time it would have stood to reason that the complexity of an organism would be proportional to the number of its unique genetic units. (Moss 2003, p. 185)

      http://books.google.com/books?id=AGm7Tg … ss&f=false

      The evidence now is that the resources for the management of cell functions reside, in part, in these non-coding protein areas as well as other areas distributed throughout the cell.
      Some recent experiments show how important the role of RNA is in phenotypic variation.

      I will point to evidence next.

    • #105350
      JackBean
      Participant

      scottie: I highly doubt, that was a compliment

      But go on and continue with your long posts, which will noone read and answer to 😉

    • #105351
      scottie
      Participant

      jackbean

      And there I was thinking I was being funny.
      🙂

    • #105367
      canalon
      Participant
      quote oldman:

      It seems to me that some of you have fallen into a classic creationist trap. You can tell by “Scottie`s” ever increasing length of arguments and his arrogance and his ”boys, if you can`t follow me, I will take it slow and easy” act. He`s showing off, obviously. He`s playing for an audience and that is really the tactics for creationists nowadays. Be strictly scientific, strictly unreligious and repeat as often as possible that the idea of evolution is really a belief system. I think it was obvious when “Scottie” stated that evolution is a fact, but only within species. To say that, you have a different motive than science. I hate to see these fake debates over and over again. I think they are harmful to forums like this and to science in general.

      I am not sure if Scottie is being harmful. He sure is not debating, as his constant refusal to answer my simple question demonstrate, and he is long winded and not very interesting. But I think that there is also a need to counterbalance the substance of his arguments to show their flaws, not in order to convince him, but to prevent those who could be convinced that there is some substance in his demonstration. So pointing out that his argument of design is essentially circular (nothing can be without design, so there must be a designer that is something [back to start]) is essential.
      However I do not think that interacting with him is useful. He demonstrates that his part of the discussion is only a way to make his points irrespectively of any arguments he is presented with, so I have no problem in using the same strategy.

    • #105370
      BDDVM
      Participant

      So I take it that Scottie still refuses to give any information about his theory. Science is not a secret society . If you want to keep secrets I would suggest keeping a diary.

    • #105373
      scottie
      Participant
      quote :

      So I take it that Scottie still refuses to give any information about his theory. Science is not a secret society . If you want to keep secrets I would suggest keeping a diary

      Who needs a diary when the evidence is publicly available.
      Canolan’s question has been answered.
      It is just that he does not like the answer so he invents arguments about circular reasoning.
      His problem is that he has not asked the scientific question.
      So let me help

      How about this most important one.

      Is my understanding of Functional Design falsifiable?

      Now this would be a reasonable question.
      But of course he is unable to argue scientifically,so he tries to get me to name the designer, as if that has some scientific merit.
      But that is his only bolt hole so I suppose he has to dive into it.

      So lets deal with what would falsify design hypothesis and also what would falsify the neo-darwinian theory.

      For a theory to be scientific it must be falsifiable.
      Yes? no one is going to argue with that are they?

      Lets start with my view.
      We all see functional design in the cell and no one seriously argues with that.
      The question is how did this functional design come about.

      My understanding is that an outside agency is responsible.

      To be regarded as science then it must be falsifiable.
      So once again, is this understanding falsifiable?
      I answer Yes, it can be falsified, and there is nothing “secretive” about this.

      Every one is aware that functional design (whether good, or not so good or even downright bad) displays itself with certain properties.
      1) The function has a purpose. ( i.e. It goes from A to B with C as it’s goal )
      2) Method by which that purpose is achieved. (How does it go from A to B)
      3) It would not contain parts or units that had no function toward the purpose.

      Therefore, falsifying this hypothesis would require that parts of the genome were non functional. Now if that was the case then that would be an argument against my hypothesis.

      So, all you have to do provide evidence that any part(s) of the genome are non functional and my hypothesis is in trouble.
      There you are, I have told you what you need to show.
      Should be quite simple, shouldn’t it?

      Now, the Darwinian or the neo Darwinian view is that this functional design has come about by random mutations of the genome filtered by natural selection with all life having developed from a common ancester.

      If this theory is to be regarded as scientific then again it must also be falsifiable.
      So What would falsify this theory?

      All you need to do is simply reveal what would be required to falsify this theory.
      Darwin himself has made some clear statements in that regard in his “Origin of Species.” So you should have no difficulty.

      So lets keep all the philosophy, religion, and misrepresentation of my posts out of this discussion and cut to the chase.

      Come on canolan,
      I know you don’t wish to continue debating with me but surely even you can rise to this simple challenge.
      After all you are the biologist and I am but (how did you put it?) an arrogant fool 🙂

      btw. I will continue pointing to more evidence on epigenetics.

    • #105405
      Abe
      Participant

      I just noticed this post today and it seems interesting. So if i understand u correctly Ur not saying evolution doesn’t occur just that it doesn’t occur randomly. is this what ur saying?

    • #105414
      scottie
      Participant

      Abe
      Thank you for your question.
      I joined this forum on the 12th April. My first post is here.
      about14351-36.html

      48 posts later, along with a certain amount of abuse being directed towards me, 🙂 has resulted in an unanswered challenge.

      The theory of design is a valid scientific theory simply because it can be falsified.
      I have shown how it can be falsified and it has resulted in my challenge to do just that.

      I am waiting for someone to inform how the Darwinian theory can be falsified.
      It has to be falsifiable if it to be counted as scientific.

      Things have gone silent on both fronts.

      So to recap for your benefit and answer your question

      quote :

      I just noticed this post today and it seems interesting. So if i understand u correctly Ur not saying evolution doesn’t occur just that it doesn’t occur randomly. is this what ur saying?

      There is good evidence that evolution (variation) does occur, but only within species.
      There is some accumulating evidence that undermines this process as purely random.
      The field of epi genetics is beginning to show this.

      I have been arguing that the (Darwinian or neo-Darwinian) hypothesis, random mutations filtered by natural selection from a common ancestor is not supported by the evidence we see in the functioning of the cell.

      I have contended that design is the correct understanding of how the cell appeared.

      I do not support either the creationist or the ID understandings as I have found difficulties with them both, although I have not explained my reasons, simply because this debate has been around Darwinian hypothesis or evolution as it seems to be commonly called.
      Hope that answers your question.

    • #105446
      scottie
      Participant

      Some further evidence that impacts on Darwinism

      Firstly by way of some basics for us non biologists!!

      Chromosomes normally come in pairs in the genomes of mammals. One is inherited from the mother and the other from the father. So any given gene occurs twice, with one version or "allele” located on the first chromosome of a pair and the other on the second.
      When the two alleles are identical, the organism is said to be homozygous for that gene; when the alleles are different, the organism is heterozygous.

      As an example, there are mice that in their natural wildtype state are dark-coloured.
      This colour is partly dependent on a gene known as Kit. These mice are normally homozygous (i.e. both alleles are identical) for this gene. However, when one of the Kit alleles is replaced with a certain mutant gene, the now heterozygous mouse developed white feet and a white tail tip.

      Now when these mutant mice were bred together, some of the offspring were again normal wildtype, which would be expected.

      However these normal wildtype mice maintained the same white spots that were characteristic of the mutants.
      Mendel’s laws of inheritance were apparently being violated.

      A trait was being displayed despite the absence of it’s corresponding gene. Something epigenetic was going on in the inheritance of the offspring.

      It appears that RNA is playing a role in this inheritance across generations
      http://cambridge.academia.edu/AlysonAsh … enerations

      This is further evidence that DNA is not the only information set that the cell is using.

      Now why is this important for theory.

      It is because Darwinian thinking has centered on the genome as being the driver for phenotypic change. Gradualism being the operative process.

      However the evidence is, that the cell as a whole determines what an organism is. Neo Darwinism has no answer for this.

      One of the most outstanding examples is the caterpillar and butterfly. Both organisms have the same genome, yet how different they are in phenotype and all this change takes place within about two weeks.

      I will of course provide more evidence of this epi genetic control that is rapidly coming to light.

    • #105447
      JackBean
      Participant

      First of all, Darwin had no idea about DNA. At the time, when he lived, the DNA was not known yet, especially not as an inheritance material.
      Second, all of your cells contain the same genome, yet they are different. However, that’s not epigenetics, only regulation of genes. Nevertheless, this has nothing to do with evolution.

    • #105451
      Genotype
      Participant
      quote :

      One of the most outstanding examples is the caterpillar and butterfly. Both organisms have the same genome, yet how different they are in phenotype and all this change takes place within about two weeks.

      Where does it say that similar genotype aren’t capable of producing different phenotypes?

    • #105452
      Genotype
      Participant

      By the way why do you use the term "Darwinism"? Does it make you feel any better?

    • #105484
      scottie
      Participant

      JackBean » Fri Jul 01, 2011 1:11 pm

      quote :

      First of all, Darwin had no idea about DNA. At the time, when he lived, the DNA was not known yet, especially not as an inheritance material.

      Correct, but what has that to do with the point I was raising?
      I have previously stated that the theory I keep referring to is the standard or neo Darwinin theory.

      quote :

      Second, all of your cells contain the same genome, yet they are different. However, that’s not epigenetics, only regulation of genes. Nevertheless, this has nothing to do with evolution.

      Actually all cells appear not to contain the same genome.
      http://www.sciencedaily.com/releases/20 … 131449.htm

      However perhaps you could describe to me what you mean by evolution. If it is the standard neo Darwinian process then it has everything to do with evolution theory.
      However you may have a different view of evolution. Do you?

      Epi genetics is the study of control other that genomic control.
      That is what epi means — extra or above.
      Also you are correct. Neither epigenetics nor gene regulation have anything to do with evolution.

      The whole point that I am arguing is whether these control mechanisms came about by random mutations of the genome from an existing organism.
      The theory of “evolution” says it does and I am arguing it does not.

      by Genotype » Fri Jul 01, 2011 6:58 pm

      quote :

      Where does it say that similar genotype aren’t capable of producing different phenotypes?

      The standard theory states that random mutations to the genome cause (gradually) the different phenotypic changes does it not?
      Are you subscribing to a different theory?

      quote :

      By the way why do you use the term “Darwinism”? Does it make you feel any better?

      I use the term “Darwinisn” simply because that is a term used by many adherents to the theory themselves.
      I feel neither better or worse in using it.

      Would you like me to use another term? If so please let me know and I will try to oblige so long as it is not in any way abusive or inflammatory.

    • #105485
      scottie
      Participant

      The Universal Code Dilemma of Darwinism.(or however Genotype would like me to refer to it as)

      In 1986 Richard Dawkins (The selfish gene) claimed that the genetic code is universal across all organisms, and cited this as evidence, indeed as near conclusive proof that every living organism in our planet descended from a single common ancestor.

      In his 2009 book The Greatest Show on Earth he reiterates this claim.

      “the genetic code is universal, all but identical across animals, plants, fungi, bacteria, archaea and viruses. The 64-word dictionary, by which three letter DNA words are translated into 20 amino acids and one punctuation mark, which means ‘start reading here’ or ‘stop reading here,’ is the same 64-word dictionary wherever you look in the living kingdoms (with one or two exceptions too minor to undermine the generalization)”

      He goes on to explain why this is important.

      Any mutation in the genetic code itself (as opposed to mutations in the genes that it encodes) would have an instantly catastrophic effect, not just in one place but throughout the whole organism. If any word in the 64-word dictionary changed its meaning, so that it came to specify a different amino acid, just about every protein in the body would instantaneously change, probably in many places along its length. Unlike an ordinary mutation…this would spell disaster. (2009, p. 409-10).(my emphasis)

      Is Dawkins correct?
      If the Darwinian mechanism is true then yes, he is correct.

      However is that mechanism correct?

      There are in fact 17 known variations of the genetic codes that have been compiled by the National Center for Biotechnology Information.
      http://www.ncbi.nlm.nih.gov/Taxonomy/ta … =cgencodes

      Not one or two minor exceptions but at the latest count 17.
      And are they minor?

      Well take the organism Mycoplasmas.
      The stop codon in the human code is UGA
      In Mycoplasmas UGA codes for tryptophan.

      In human cells therefore when the ribosome meets up with UGA in the messenger RNA it stops translating. (UGA is code for STOP)

      In Mycoplasma the ribosome would insert tryptophan into the mRNA and would continue translating until it reached the Mycoplasma stop codon.

      Is that serious?
      Well Craig Venter explained it well to Richard Dawkins and Paul Davies during a discussion at Arizona State University earlier this year.

      Watch here from about 6min:30sec to about 11min:45

      http://thesciencenetwork.org/programs/t … life-panel
      enjoy

      Contary to what Richard Dawkins believes There is no tree of life. .

      This is from a bio-engineer who knows what he is talking about. At least Paul Davies concedes to Venter.
      Dawkins however is really troubled about this.

      Listen carefully to his response to Venter and Venter’s polite chuckle.

      In my next post I will show how the Darwinian mechanism fails to show how a prokaryotic cell could have evolved into a eukaryotic cell

    • #105533
      LeoPol
      Participant

      Hmmm. So, once, a few billion years ago created a reasonable membranes, standardized first version of the peptide-nucleic molecular technology, and armed with her​​, travel to the Metagallaktik. Then somewhere a bit more than once the standard has changed, but the basics remain the same. But the main thing – the version of Darwinism, according to which natural selection is combined not with the "Evolution" – from simple replicators to the "crown of creation", but with vice versa, the "Devolution" from a reasonable universal form – to super-specialized species of dead-end.
      http://translate.google.com/translate?hl=ru&sl=ru&tl=en&u=http%3A%2F%2Fspacenoology.agro.name%2F
      Excuse me my inglish Google 🙁

    • #105538
      Genotype
      Participant
      quote scottie:

      The standard theory states that random mutations to the genome cause (gradually) the different phenotypic changes does it not?
      Are you subscribing to a different theory?

      Does it state mutations alone can cause pheontypic changes? That seems to be your point, right? I’d love some sources on that. Phenotype is usually the result of both genetic and environmental factors.

      And what you’ve talked above is metamorphosis, what has it got to do with TOE?

      quote scottie:

      quote :

      By the way why do you use the term “Darwinism”? Does it make you feel any better?

      I use the term “Darwinisn” simply because that is a term used by many adherents to the theory themselves.
      I feel neither better or worse in using it.

      Would you like me to use another term? If so please let me know and I will try to oblige so long as it is not in any way abusive or inflammatory.

      Theory of evolution please. We’re thankful to Darwin that he’s formulated perhaps the one of the most solid theories in science, but modern TOE has come leaps and bounds since. And we’re talking about genetics, I don’t see why you’d call it "Darwinian" anyways.

      Oh btw I’m a newtonian too 😉

    • #105539
      Genotype
      Participant

      By the way, I’d like you to cite some sources before you respond, I can barely understand what you’re saying.

    • #105606
      scottie
      Participant

      Leopol
      Thank you for your comment.
      As I understand, you appear to dispute the Darwinian theory yourself.
      I wish I could do as well in Ukrainian as you do in English.

      Genotype
      Thanks for your response.
      My apologies for not responding sooner but I have been away and am only just catching up on things.

      Lets start with some sources of (neo)darwinian theory
      http://www.jstor.org/pss/2408095
      In part this source states

      quote :

      “These authors broadly agree with Darwin’s view that the most important evolutionary changes at the level of the visible phenotype, as revealed by paleontological and systematic studies, have resulted from natural selection acting on variation within populations. This variation is ultimately due to mutations that arise at random with respect to the direction of selection.”

      It goes on to describe challenges to this theory, in particular by Gould where it quotes Gould in part

      quote :

      “.. The pattern of morphological stasis for most lineages and the sudden appearance of new forms is contrasted with the alternative mode of gradual evolution of species.”

      There are perhaps differing views at the edges of this but the foundation pillar is the random mutation of genome filtered by natural selection from a common ancester and that this process is gradual. You just have to read Dawkins, Coyne and indeed others to note that gradualism is prominent. Small incremental steps of random change.

      Also try this
      http://en.wikipedia.org/wiki/Neo-Darwinism

      Sorry you are having trouble understanding my posts. I will try and be a little clearer.

      My reference to metamorphosis simply illustrates that changes in phenotype do not require changes in genotype as the theory states. Something else is at work.
      This contrasts with the Dawkin’s "selfish gene" and "mount improbable" for instance.

      Good to hear you are a Newtonian. He did get a lot right. 🙂

    • #105608
      Genotype
      Participant
      quote :

      My reference to metamorphosis simply illustrates that changes in phenotype do not require changes in genotype

      I agree

      quote :

      as the theory states. Something else is at work.

      Nope, the theory doesn’t state that mutations ALONE can cause change in phenotypes. Where does Dawkins or anyone say that?

    • #105614
      LeoPol
      Participant

      to scottie

      Yes? Ukrainian? And I try to write in Russian … This is very good. I can easily understand what translate Google from English! Then take a look here is more!

      We almost all remember from biology: "ontogeny recapitulates phylogeny." This is according to the theory of evolution. And from the standpoint of the theory devolution – "ontogeny repeats metamorphosis of primary universal amphibians". From the standpoint of those of amphibians, our "embryo" – it’s unfortunate larva, devoid of happiness independent existence during the most exciting stages of childhood – from the stage myuller-larve! 😀

    • #105631
      scottie
      Participant

      Leopol

      Nice sense of humor. I must remember that one. 🙂

      Genotype
      Please read my post in it’s entirety. I responded to your request to provide citation..
      I did with the direct quote from “A Neo Darwinian commentary of Macroevolution”
      That very specifically states

      quote :

      This variation is ultimately due to mutations that arise at random with respect to the direction of selection.”

      Now if you disagree with that postulate then your disagreement is not with me but with the authors of the commentary.
      I also did state very clearly that

      quote :

      There are perhaps differing views at the edges of this but the foundation pillar is the random mutation of genome filtered by natural selection from a common ancester and that this process is gradual.

      So I standby my statement.

      The whole interest in the study of epigenetics is precisely because the understanding that mutations of the genome are the driver for the theory is rapidly being eroded.
      Why else are distinguished scientists like Margulis, Koonan and many others distancing themselves from the neo-Darwinian hypothesis ?

      Richard Dawkins “Selfish Gene” recounts a gene centric view of change.

      In his book “Climbing Mount Improbable”
      Well —Wikipedia describes the book this way

      quote :

      In the book he gives various ideas about a seemingly complex mechanism coming about from many different gradual steps, that were previously unseen.

      http://en.wikipedia.org/wiki/Climbing_Mount_Improbable

      If you read the summary of the modern synthesis you will note that the again the evolution of species revolves around gradual genomic changes.
      Check it out here.
      Summary of the modern synthesis
      http://en.wikipedia.org/wiki/Modern_evo … _synthesis

      btw I have repeatedly tried in past posts to get my detractors to elaborate what actual theory or hypothesis they subscribe to. But none one yet has seen fit to respond.

      You disagree with me with a NOPE, however I don’t know what your understanding is.
      Would you be prepared to elaborate.

      Thanks

    • #105632
      scottie
      Participant

      I would now like to continue

      The theory of common descent, simply postulates that all life evolved from one kind of organism and that each species arose from another species that preceded it in time. Each group of organisms shares a common ancestor.

      The prokaryote cell is postulated to have arisen before the eukaryote cell.
      http://evolution.berkeley.edu/evolibrar … mbiosis_03

      This is a challenge to the standard theory because random mutations in the genome is clearly not the answer.

      Therefore how does, or what is the mechanism that turns a cell without a nucleus ie a prokaryote into a cell with a nucleus a eukaryote. There are some similarities between the two types of cell, however there are also many other differences as well.

      This is where the Endosymbiotic theory enters, to postulate the mechanism by which this all came about.

      http://www.biology.iupui.edu/biocourses … osymb.html
      The Endosymbiotic Theory first postulated by Lynn Margulis in the 1967.

      However Lyn Margulis rejects the Darwinian mechanism of random mutations and Natural selection.
      http://discover.coverleaf.com/discoverm … pg=68#pg68

      So let’s take her starting point.

      quote :

      “Margulis’ original hypothesis proposed that aerobic bacteria (that require oxygen) were ingested by anaerobic bacteria (poisoned by oxygen), and may each have had a survival advantage as long as they continued their partnership.”
      quote :

      “1. . The timeline of life on Earth:
      a. Anaerobic bacteria: Scientists have fossil evidence of bacterial life on Earth ~3.8 billion years ago. At this time, the atmosphere of the Earth did not contain oxygen, and all life (bacterial cells) was anaerobic.”

      http://www.ux1.eiu.edu/~cfjps/1400/atmos_origin.html
      When you read the above it all sounds very plausible.

      So What is the actual evidence?
      The simple answer is there is none.
      Just check out the papers listed below.
      http://www.sciencedirect.com/science/ar … 6888900228
      http://memoirs.gsapubs.org/content/198/121.abstract
      http://www.sciencedirect.com/science/ar … 3779902382
      http://www.phys.uu.nl/~wettum/vakken/st … er%201.pdf
      http://www.chem.duke.edu/~jds/cruise_ch … earth.html

      What we do have is an awful lot of speculation.
      The fuel for all this speculation is simple to understand.

      Life could not have got started naturally in an atmosphere that contained oxygen.
      Any schoolboy chemist would be able to explain the chemistry of why that cannot happen.

      I could of course go into the physics and chemistry of this should anyone wish to dispute this. In fact I would welcome someone to rebut this.

      This theory therefore falls at the first evidential hurdle.
      My point is simple. Someone needs to produce some evidence other than tall tales about what may have led to an early earth atmosphere containing no oxygen.
      Speculation is not science.
      Of course there is a lot more but lets leave that for another post.

    • #105633
      LeoPol
      Participant

      Yes, you’ve collected all the basic propositions around which is a long argument. It’s all about, I repeat once again – in the synthesis of the theory of evolution (from simple replicators to "crown selection") and natural selection. But personally, I abandoned this "evolution" and replace it with "devolution"! And this "Darwinism" was stable enough! http://translate.google.com/translate?h … ge_id%3D82
      That think is IRREVERSIBLE the loss of a free stage for larvae placed our "embryo" in the egg, then – in the genital tract for pregnancy. But the frog "embryo" is placed in the egg stage only with fish (Turbellaria And today, there is also a form of free-floating planula!)! Hence, the ancestors of amphibians also have the same nymphs in their voluntary metamorphosis! But this is Stegocephalia! So, coelacanth, then ihtiostega, akantostega – this is not adult organisms, but the intermediate stages of metamorphosis Stegocephalia! Oh, how we lie to many paleontologists for this silly theory of evolution! 😛
      A modern fish, respectively – the victim of neoteny as the axolotl, in which the land morphology all lost. But in flatworms (parasite – fasciola) stage of the fish – adolescariae …

    • #105634
      JackBean
      Participant

      scottie: you are again and again providing just piece of information so that it looks nice for your picture, right?
      The endosymbiotic theory does not say, how eukaryotes evolved, but how did we obtain the mitochondria and chloroplasts.

      The actual evidence are genetic data of plastids, mitochondria and bacteria. It has nothing to do with the oxygen level.

      I’m sure that you are much more than a schoolboy chemist, so you will be for sure able to explain to me, why couldn’t life evolved, right? And NO LINKS! I won’t read any links, I won’t read anything what you won’t type by yourself into this forum, so stop posting plenty of articles. Noone is reading that anyway.

    • #105643
      LeoPol
      Participant

      So the answer to these questions from the perspective of macro-devolution !

      You know, as different from each other different "experts" in the termite hill? And termites – it’s obviously – a relic of the paleo-civilization. Cells in multi-cellular organism – and it’s so clear. Too – an obvious relic paleo-civilization! Well, some specialized Protista – members of the first communities of myxomycetes more billion years ago – had a specialty: work with photosynthetic bacteria. A mitochondrion domesticated even earlier – to multicellularity! Planted this bacterium in a membrane interesnub pocket and used as a generator … Spent the most appropriate selection of the mitochondria … Then plastids selected such that proliferated in the membrane pockets, but chloroplasts evolved into active only at a special incentive-team. And – "Cambrian explosion"? Also a consequence of some of the early Cambrian paleo-civilization! Twists in the caste society with a global division of labor morphological polymorphism … Then different castes in a separate race, species.
      😉

      http://translate.google.com/translate?j … ge_id%3D32

    • #105652
      CarlosG
      Participant

      I can’t help but to think that Scottie is a Turing test stuck in a cycle of sorts. 😀

    • #105666
      scottie
      Participant

      jackbean

      quote :

      scottie: you are again and again providing just piece of information so that it looks nice for your picture, right?

      That is what any rebuttal is all about.
      If you disagree with me then you should do likewise. Rebut with evidence.

      quote :

      The endosymbiotic theory does not say, how eukaryotes evolved, but how did we obtain the mitochondria and chloroplasts.

      A prokaryote cell is a cell without a nucleus or other membrane-bound organelles
      A eukaryote cell contains structures enclosed within membranes. These structures include a nucleus that contains dna, a mitochondria that also contains dna or likewise chloroplasts.

      Now you should have noticed that I provided two citations in introducing the theory. The first that does not mention the early conditions and the second that does postulate the early conditions.

      In fact the first from Berkley is entitled “From prokaryotes to eukaryotes”
      Pretty clear I would argue.

      My critique of the theory cantered on the early conditions, and the speculation that surrounds those conditions.

      I would encourage you to read carefully what I have written.
      I wrote
      This is where the Endosymbiotic theory enters, to postulate the mechanism by which this all came about.

      My criticism was about the mechanism (i.e. the endosymbiotic idea).
      Endosymbiotic theory encompasses all the organelles that are enclosed in membranes.

      quote :

      The actual evidence are genetic data of plastids, mitochondria and bacteria. It has nothing to do with the oxygen level.

      The theory is about the origin of the organisms. I am surprised you miss such an obvious point. This thread is all about theories of origins.

      quote :

      I’m sure that you are much more than a schoolboy chemist, so you will be for sure able to explain to me, why couldn’t life evolved, right? And NO LINKS! I won’t read any links, I won’t read anything what you won’t type by yourself into this forum, so stop posting plenty of articles. Noone is reading that anyway

      For sure I do have fond memories about my schooldays 🙂
      My last 50 odd posts have dealt in some detail how life could not have evolved in the way it is being promoted.

      I appreciate you don’t like citations, however without citations I would simply be positing personal opinions. Science advances through proper documentation of research and therefore citations are important in explaining scientific matters. I would encourage you to read any accredited citation in order to fully appreciate,that any statement does have proper support.

      I will therefore of course continue to support my statements with proper citations. Whether you choose to read and check them out is for you to decide.

    • #105691
      scottie
      Participant

      I was not aware that this forum catered for advertsiments.

      Jackbean

      Genotype wants me to provide citations and you don’t want me to.
      So what I suggest is that you read my posts that don’t include citations and Genotype read those with citations. That way both of you will be more comfortable. 🙂

      This one is for you .

      Let me try and consolidate my views as to why life could not have evolved by any natural process but as a result of design by an outside agency.

      By evolved I mean some chemical combination of molecules (non life) somehow turning into some living organism.
      This life in turn changes into other forms of life due to random processes acting on the organism

      Let’s take the supposedly simple prokaryote cell.

      This cell is hundreds of times smaller than the period at the end of this sentence.

      There is a tough, flexible membrane that acts something like a brick wall surrounding a factory. It would take some 10,000 layers of this membrane to equal the thickness of a sheet of paper.
      But this membrane wall is no simple brick wall.

      This membrane shields the contents of the cell from a hostile environment, however it is not solid. It allows small molecules such as oxygen to pass in and out but blocks larger and more complex molecules from entering without permission. It also prevents the useful molecules within the cell from leaving.

      There are special protein molecules embedded in this membrane wall that act like doors.
      Some of these proteins have a hole through the middle that allow only certain types of molecules in and out of the cell.
      Other proteins are open on one side of the membrane and closed on the other.
      They have a docking site shaped to fit a specific substance, so that when the particular substance docks, the other end of the protein opens to allow the cargo through.

      As you should already know this activity is just a very small part of the protective wall surrounding even the simplest of cells.

      Now I don’t need to go into any further depth to ask some simple questions

      Does this membrane (wall) have a purpose? Answer — Clearly yes
      Does it have function to fulfil that purpose? Answer — Again yes
      Does it have predictability, i.e. can we know what will and what wont be allowed through? Answer — yes.

      Are these all the attributes of design and with a specific purpose by an outside agency?
      Again the answer is yes, with the proviso that nothing else can explain these attributes.

      So, is there another possibility?

      If you contend that there is then please explain what that can be.

      Now I have asked for those who disagree with me, and that includes both you and genotype, to put their own viewpoints or theories forward so that they can be scrutinised.
      Nobody — including you, has come up with any explanation that you may wish to be held up to scrutiny.

      So why not?
      There is a concept that is referred to as “wilful or deliberate blindness”

      Is that what is going on here?

    • #105697
      scottie
      Participant

      Jackbean

      Genotype wants me to provide citations and you don’t want me to.
      So what I suggest is that you read my posts that don’t include citations and Genotype read those with citations. That way both of you will be more comfortable.:)

      This one is for you .

      Let me try and consolidate my views as to why life could not have evolved by any natural process but as a result of design by an outside agency.
      By evolved I mean some chemical combination of molecules (non life) somehow turning into some living organism.
      This life in turn changes into other forms of life due to random processes acting on the organism

      Let’s take the supposedly simple prokaryote cell.

      This cell is hundreds of times smaller than the period at the end of this sentence.

      There is a tough, flexible membrane that acts something like a brick wall surrounding a factory. It would take some 10,000 layers of this membrane to equal the thickness of a sheet of paper.
      But this membrane wall is no simple brick wall.

      This membrane shields the contents of the cell from a hostile environment, however it is not solid. It allows small molecules such as oxygen to pass in and out but blocks larger and more complex molecules from entering without permission. It also prevents the useful molecules within the cell from leaving.

      There are special protein molecules embedded in this membrane wall that act like doors.
      Some of these proteins have a hole through the middle that allow only certain types of molecules in and out of the cell.
      Other proteins are open on one side of the membrane and closed on the other.
      They have a docking site shaped to fit a specific substance, so that when the particular substance docks, the other end of the protein opens to allow the cargo through.

      As you should already know this activity is just a very small part of the protective wall surrounding even the simplest of cells.

      Now I don’t need to go into any further depth to ask some simple questions

      Does this membrane (wall) have a purpose? Answer — Clearly yes
      Does it have function to fulfil that purpose? Answer — Again yes
      Does it have predictability, i.e. can we know what will and what wont be allowed through? Answer — yes.

      Are these all the attributes of design and with a specific purpose by an outside agency?
      Again the answer is yes, with the proviso that nothing else can explain these attributes.

      So, is there another possibility?

      If you contend that there is then please explain what that can be.

      Now I have asked for those who disagree with me, and that includes both you and genotype, to put their own viewpoints or theories forward so that they can be scrutinised.
      Nobody — including you has come up with any explanation that you may wish to be held up to scrutiny.

      So why not?
      There is a concept that is referred to as “wilful or deliberate blindness”

      Is that what is going on here?

    • #105706
      scottie
      Participant

      For those who accept citations in support of posts.

      Accordingly to Freeman/Herron’s Evolutionary Analysis Chapter 17, there are currently about 4 different hypotheses regarding Origin of Life.
      http://wps.prenhall.com/esm_freeman_evo … index.html

      Here they are with their comments in an end of chapter summary questions.

      "The "universal gene-exchange pool" hypothesis proposes a time when genomes were modular, and when organisms assembled their genomes from a common pool. It is not yet clear whether this system is stable and feasible, or whether it could give rise to Darwinian natural selection.

      The ring-of-life hypothesis proposes that eukaryotes arose from a fusion of archaeans and bacteria. However, this hypothesis cannot explain where eukaryotes got their unique genes, and how fusion could have occurred in the two groups that lack a cytoskeleton.

      The chronocyte hypothesis proposes that eukaryotes arose from a long-vanished lineage of "chronocytes", one of which engulfed an archaean that became the eukaryotic nucleus. No such chronocytes exist today, but perhaps the eukaryotes’ unique genes represent a remnant of the genome of a chronocyte ancestor.

      Finally, the "three viruses, three domains" hypothesis integrates viruses into the picture, proposing that (a) viruses are a remnant of the RNA World, (b) viruses evolved DNA during arms-race coevolution with their hosts, and (c) three such viruses then converted the three domains from RNA to DNA. Evidence from viral genomes offers a modest amount of support for this hypothesis, though more viral genomes are needed to thoroughly test the hypothesis.

      These four hypotheses offer creative and varied ideas for the solution of the puzzle of life’s origins. Which of these four is true, if any, we cannot say yet. But the more we learn, the more it appears that the early history of life on Earth was strange indeed."

      You will notice that they all begin with a premise that life is already in existence.
      So for a start this analysis has nothing to do with actual origin of life.

      What is really interesting however is that one of these hypothesis has had to invent a new life form as a starter for the hypothesis.
      It is called the chronocyte. 🙂

      What is more interesting is that this mythical creature is actually the subject of a paper that appeared in PNAS entitled
      The origin of the eukaryotic cell: A genomic investigation
      http://biologia.uab.es/biocomputacio/tr … 20endo.htm

      So here we have an august scientific body resorting to or endorsing mythical creatures to try and substantiate scientific ideas.

      Is this what science is being reduced to?

    • #105781
      scottie
      Participant

      There is a body of opinion within this debating controversy that argues this way.—

      The Darwinian evolutionary process does not engage with origin of life scenarios, but only addresses how an existing organism has changed in form and function to produce the variety of life forms that exist today.
      The process that achieves this is the random variations of the genome that change form and function and is then filtered by Natural selection.

      The problem that even this argument has is, it fails to account for the actual observations we note in cellular processes.

      What is being discovered in cell investigation is not just a linear array of code in DNA, but a total integrated information processing system.

      We are learning that DNA is not even nearly the whole answer.

      DNA codes for proteins that do the important work in the cells.

      These proteins though have to be arranged into more complex or higher cell structures
      Cell types then have to be arranged into tissues.
      Tissues in turn have to be arranged into organs.
      These organs in turn have to be arranged into entire body plans, the forms we see in life.

      These higher forms of organization are not fully understood, but it is clear that there are higher orders of information in the cell that are above DNA

      DNA does not control all those higher orders of information.

      DNA codes for proteins.

      So there is this information hierarchy in the cell, and DNA is at the lowest level.
      So clearly DNA alone does not control the formation of body plans.

      Now the problem for the neo Darwinian synthesis (the modern theory of evolution in any of it’s forms) is that this theory attempts to describe how random mutations in DNA (the lowest level of information in this hierarchy) is responsible for new biological forms.

      Since DNA alone is not responsible for biological form, no amount of mutations, random or even otherwise can produce new organisms.

      This is why this materialist Darwinian concept is defunct.
      It can’t account for the origin of form let alone life itself.

      It is therefore very clear to me why I have had no responses to my repeated requests from those critical of my postings, to put on record what their actual scientific understanding is on this subject.

      Sorry I must correct myself here, one critic did accuse me of lacking imagination. 🙂

      Evolutionary theory is a materialist philosophy and not a scientific concept.

    • #105839
      scottie
      Participant

      Quorum Sensing

      Following on from my post on the hierarchical layers of information in the cell, further information on this has emerged in recent years.

      There is the phenomenon of “quorum sensing”.
      This is a mechanism by which bacteria communicate with one another.
      The purpose of this communication is to establish the population density of a species of any of these micro-organisms within a local environment.

      A single bacterial cell that secretes a toxin into an organism is not likely to cause any harm to the host. However if there are sufficient numbers around a host, joint expression of the toxin is more likely to have the desired effect.
      In other words this communication allows bacteria to collectively regulate gene expression.

      Professor Bonnie Bassler of Princeton University gave a TED talk recently where she explains this phenomenon far more interestingly and in layman terms.

      Well worth watching.

      http://www.ted.com/talks/bonnie_bassler … icate.html

      When you have watched this you may well wonder what Darwinian process led to this coordinated activity. 🙂

    • #105846
      Eon
      Participant

      Evolution is a scientific fact – this is not an opinion, there is a plethora of evidence that validates that statement.

      quote scottie:

      Evolutionary theory is a materialist philosophy and not a scientific concept.

      You have the stink of a Creationist that is merely trolling this particular topic thread.

    • #105848
      scottie
      Participant

      I produce evidence from accredited sources and you respond with philosophic and defamatory rhetoric.

      Is that your best argument? 🙂

      Which part of "evolution is a fact" as you put it, is a fact?

    • #105849
      Eon
      Participant
    • #105850
      scottie
      Participant

      From your supplied link

      This is how Kellogg introduces his proposal.

      quote :

      “Introduction
      Phyletic change, is best defined as “change with respect to time of characteristics of a species” (Bock, personal communication), is possibly the best documented aspect of evolution in the fossil record. (Simpson 1953, page 385)….

      More recently, Eldridge (1971) and Eldridge and Gould (1972) have proposed as an alternative to evolution by “phyletic gradualism,” a concept of “punctuated equilibria,” which they believe to be more in keeping with the discontinuous nature of the fossil record. I agree with Eldridge and Gould…..”

      Point 1
      His first sentence clearly states the best documented aspect of evolution is “ change with respect to time of characteristics of a species.

      Are you not aware that this change is within a species.

      I am not aware that anyone disagrees with this micro evolutionary change.
      Not even creationists as far as I am aware.
      May I encourage you to read what I have written, not what you think I have.

      Point 2
      Kellogg clearly recognised this and that is why he in this paper agrees with Eldridge and Gould on their “proposal” of punctuated equilibra

      So he doesn’t agree with gradualism but prefers punctuated equilibrium.

      Again are you not aware that these are proposals or hypothesis and not fact as you have so confidently asserted

      Point 3
      Let me refer you to his website here
      http://www.geology.um.maine.edu/user/Da … blications
      This is what he states are his interests

      My interests are in three fields of study:
      1. Evolutionary Biology, particularly the tempo and mode of evolution. I pursue the long continuous records of siliceous microfossils in deep-sea sediment cores to test hypotheses about the rate and timing of morphologic change – is it continual, continuous, or episodic; what does that tell us about the nature of evolution at and above the species level? I am also interested in the more purely philosophical questions of species individuality, and the ethical implications of evolutionary biology…….

      Notice he presents his hypothesis. Of course he is not sure whether change is continual, continuous, or episodic.

      Now if you wish to present hypotheses as facts then may I suggest you get a clearer understanding of the meaning of terms used in science.

    • #105856
      JackBean
      Participant

      how does the DNA thing and quorum sensing provide proofs against evolution?

    • #105875
      scottie
      Participant

      Jackbean

      quote :

      how does the DNA thing and quorum sensing provide proofs against evolution?

      May I refer you to my post below.

      about14351-168.html
      by scottie » Mon Aug 01, 2011 7:44 pm

      There I explained that there are different levels of information that govern cell processes.

      The DNA coding resides at the lowest level and codes for protein.

      Above that, is a level of information that differentiates into cell types that then have to be arranged into tissues.
      We don’t know where the information that controls this process resides.

      Above that then, we have information that controls the arrangement of the tissues into organs
      We we don’t know where that information resides.
      These organs then have to be arranged into body plans, the forms we see in life.
      Again ditto

      Now these higher levels of organization go beyond the DNA level.
      In other words DNA does not control these higher order processes.
      DNA controls the form and expression of proteins.

      This is why changes in DNA (however incurred) can only alter the protein level.
      Now Darwinian theory ( I have to assume that you subscribe to Darwinian theory) only deals with mutations to DNA.

      Therefore you can mutate DNA as much as you like and no new forms of organisms will arise.

      Quorum sensing is just another demonstration of the higher orders of information that control cell processes.

      In fact it appears that the information being used is above even cell level.

      You will have noticed that Bonnie Bassler explained that there is communication not just between bacteria of the same species but also between different species.

      All this information is quite definitely not being controlled by DNA.

      Therefore evolution theory of any description that is based on DNA modifications simply cannot account for the forms and communication levels we see in nature.

      What makes these theories even more unrealistic,is that they are all firmly rooted in the notion of random modifications of DNA.
      Yet all over we see highly non-random structures.
      I have covered this is previous posts.

      It is not my intention to destroy anyone’s belief. People have different belief systems and I feel they should be respected even if one disagrees with them.

      The problem evolutionary theory has is that it is portrayed as a scientific fact, and has been made into a dogma that has to be obeyed.
      Anyone who dares to oppose it is branded some sort of a heretic.

      So if something is portrayed as a scientific fact then it has to be shown to be so using known science. If it can’t be then it is simply another philosophy.

      Clearly evolutional theory fails in this regard, as I have been trying to show over these past months.

      The creationists are also entitled to believe whatever they want to and I also believe that their view should be respected.

      However if they (and many of them do) claim that the universe was created in 6 24 hour days because the genesis account in the bible states that, then I have to take issue with that as well. There are other issues as well.

      The genesis account says nothing of the kind and I suppose in due time I will be called on to prove it.

      Now as regards the ID community.
      Well, while they have a lot of good science they call upon, I again find there is not a consistency in their composite view.
      I can go on to explain if asked, but I think this posting is long enough.

      Hope that answers your question.

    • #105881
      WinterImp
      Participant
      quote mcar:

      I have thought if they’re viruses but since you have said “phospholipids” my thought lead me to a true cell.

      Please correct me if I’m wrong on this, but aren’t all known viruses parasitical? That is, they are basically reproductive molecules that require the use of another organism’s host cells to replicate themselves. The virus takes over the cell’s own DNA and causes it to replicate the virus instead. If that’s so, then the first organisms couldn’t very well have been viruses. Am I missing something?

    • #105894
      scottie
      Participant

      No you are not missing anything.

      Wikipedia describes a virus this way
      “Virus particles (known as virions) consist of two or three parts: the genetic material made from either DNA or RNA, long molecules that carry genetic information; a protein coat that protects these genes; and in some cases an envelope of lipids that surrounds the protein coat when they are outside a cell.”

      Question
      How is the protein manufactured? — In a cell

      Since a cell is required to manufacture protein, how on earth can anyone postulate that virus could have appeared before cells.

      All this speculation is nothing but just that.
      There is no science behind all this.

    • #105923
      scottie
      Participant

      The scientific merit of the Darwinian macro evolutionary account in all it’s forms, as the accumulating evidence shows is rather tenuous and unravelling rapidly.
      There is fierce resistance but that can only last so long.

      What about the Genesis account, which is the other main view?

      Firstly it is important to recognise that the account is presented as a historical narrative as
      Gen 2:4 clearly states.
      “ This is the history of the heavens and Earth in the DAY of their being created. in the DAY that God made earth and heaven.”

      The word day (Hebrew yowm) is used 15 times in the account and it’s meaning varies depending on the context.

      It varies from the distinction between light and darkness (night and day, i.e. roughly about 12 hours) to and unspecified creative period, finally to all the creative periods together, as the quote above clearly demonstrates.

      Now the creationist (in particular the young earth) view is that the days mentioned in the account represent 24 hour periods.
      There is no internal evidence that this is so. In fact there is nothing in the account to warrant an understanding that these created days were literal 24 hour periods.

      The 24 hour period for each creative day is clearly a dogma and not based on evidence.

      However can any part of the account be analysed scientifically?
      The first 8 verses relating to Days 1 and 2 simply cannot.

      However the process attributed to day 3 is interesting.
      Vrs 9 & 10 reads
      And God said, Let the waters under the heaven be gathered together unto one place, and let the dry [land] appear: and it was so.
      And God called the dry [land] Earth; and the gathering together of the waters called he Seas: and God saw that [it was] good.

      Current scientific understanding does seem to support this statement.
      The evidence below shows that current science agrees that the landmass of the earth was all in one place in the past.

      http://pubs.usgs.gov/gip/dynamic/historical.html

      http://www.time.com/time/magazine/artic … 74,00.html

      http://en.wikipedia.org/wiki/Pangaea

      http://pubs.usgs.gov/gip/dynamic/polar.html

      There are some other points worthy of note but I will leave that to another post

    • #105949
      canalon
      Participant

      Thanks Scottie,

      Finally showing your true color and answering to the question, you take the christian god for the creator.
      Would you provide evidence that the genesis account is the other main view. I seriously doubt that.

      And how cute it is to see you cherry picking verse to shoehorn science in that view. So a few more questions:
      – Why Genesis 2, and not Genesis 1? Both chapters contain a creation myth.
      – But they are diffrent so I do you chose which is more true, considering that, as you handily provide evidence for (at least for Gen 2), the link with our scientific understanding of the creation of the earth is quite hmmm…. patchy, shall we say?
      – Do you know your Geology? And do you read your links? Because Pangea was not the first mega continent, and it is probably impossible to say waht the first continent or group thereof looked like.

      But at least we can agree on something, your post on the origin of virus is correct. Since they are parasites and cannot self replicate, virus cannot be at the origin of life.

    • #105961
      scottie
      Participant

      Patrick

      Glad to see you have come “alive”again.
      You had gone very quiet recently, mind you it came as no surprise to me since your previous arguments fell apart.

      Whatever happened to your last comment on this thread, remember this

      quote :

      Thank you for your demonstartion of your ignorance and stupidity. That will be my last post in this thread.

      about14351-132.html
      🙂

      But you are alive again so let me remind you that you still have not put to record which evolutionary account you subscribe to.
      Why are you finding it so difficult to respond to such a simple question?
      Well I am not going to hold my breath on any response on this.

      However let me deal with your assertions one by one.

      quote :

      Finally showing your true color and answering to the question, you take the christian god for the creator.

      (btw. my favourite colour is green, I have a suspicion yours will be gravitating toward red. 🙂 )

      First of all I was providing an answer to MY rhetorical question.

      The genesis account refers to the God of the Hebrews, not to your so called “christian god”.
      A good piece of advice is to know your subject before you start making strong assertions.

      quote :

      Would you provide evidence that the genesis account is the other main view. I seriously doubt that.

      No no be in no serious doubt at all.
      The creation view is most definitely the other main view of origins with the main creation account found in genesis.
      Why? here is the reason.
      Tell me do you attack with the same disparaging comments anyone espousing a different view from Darwin’s hypothesis but still positing a materialist stand?
      Ofcourse you don’t.

      There could of course be a couple of reasons for this
      (a) you are not really sure what your own view is, which I suspect is the case since you are so reticent to put it to record. But also
      (b) it doesn’t really matter to you what is proposed so long as that view does not interfere with your philosophy.
      I have repeatedly made the point that these materialistic hypotheses are grounded in a philosophical view and not a scientific one. Prove me wrong.

      Now just state quite clearly what your view is and the scientific basis for it and we can then examine the veracity of it.
      Don’t keep catcalling from the sidelines. It demeans you.

      quote :

      Why Genesis 2, and not Genesis 1? Both chapters contain a creation myth.

      Because there is only one creation account in genesis.
      The creation account of chapter one ends in chapter 2:4.

      Now before you go ahead and display any more lack of understanding on this subject I would advise you to get at least a smattering of knowledge of this matter.

      quote :

      – But they are diffrent so I do you chose which is more true, considering that, as you handily provide evidence for (at least for Gen 2), the link with our scientific understanding of the creation of the earth is quite hmmm…. patchy, shall we say?

      Not quite sure what you are getting at here apart from the obvious sarcasm (which of course I am getting used to 🙂 ) but let me try to educate you a little.

      The original genesis account was an edited version from pre existing histories that were inscribed probably on clay tablets.

      The chapter headings and verses we see in bibles today are the work of translators of the King James Version of 1611. They are not the originals.
      (there is a little bit more but I am not going to bore you with the details)

      The genesis account is an edited version of 12 histories, each history concluding with the chapter and verses as follows.
      Chapter 2:4, 5:1, 6:9, 10:1, 11:10, 11:27, 25:12, 25:19, 36:1, 36:4, 37:2 and the last 50:26.

      Note please these are historical accounts. I am not cherry picking anything, but merely examining anything from the account that could be in accordance with known science.

      So please read what I am actually writing not what you may wish it to be.

      quote :

      – Do you know your Geology? And do you read your links? Because Pangea was not the first mega continent, and it is probably impossible to say waht the first continent or group thereof looked like.

      Yes I do know my geology, and yes again and I do read the links I provide.
      I suggest you read the USGS link properly.

      First, you will not find that I used the word Pangea anywhere in my post.
      Secondly the name Pangea relates to the “Continental drift theory” not plate tectonics.

      Now Patrick you are showing signs of desperation here.

      Neither I nor the genesis account (1:1 to 2:4) mention any geographical names.
      A feature of the account is the fact that no geographical names are mentioned.
      Even the sun and moon are referred to as the greater and lesser lights.
      This suggests that the account was initially set down before any geographical names were invented.
      Geographical names first appear in Chapter 2:8.

      Also the account and I make no mention of what the land mass looked like, simply that it was all in one place, just as the modern day view is, that is all.

      Are you trying to introduce a red herring in an attempt to camouflage some interesting information?

      Now there are a few more interesting little nuggets but I had better wait until you cool down a bit before I enrage you again.

    • #105980
      scottie
      Participant

      canolan

      I forgot to respond to your last comment regarding your agreement with me.

      quote :

      But at least we can agree on something, your post on the origin of virus is correct. Since they are parasites and cannot self replicate, virus cannot be at the origin of life.
      Patrick

      Well actually I am not exactly in agreement with you here.

      The virus could not predate the cell because it is essentially a protein shell housing some bits of nucleic acid (either DNA or RNA, depending on the virus) but not because it is a parasite which of course it is.

      Protein could only come from a pre existing cell process.
      The cell had to have predated the protein because it contains the processes that make protein.
      So if we are to have common ground, and it’s nice to have some, I would like to be clear what that ground actually is.

      This is an important fact as I hope will become clear.

      A specially commissioned piece of research by NASA is available online by the National Academies Press entitled
      The Limits of Organic Life in Planetary Systems
      http://www.nap.edu/catalog.php?record_id=11919

      Here are some extracts.
      http://www.nap.edu/openbook.php?record_id=11919&page=59

      quote :

      Briefly summarized, it suggests that existing prebiotic chemistry experiments do not offer plausible hypotheses for routes to complex biomolecules……

      Those facts generate the central problem in prebiotic chemistry. Spontaneous self-organization is not known to be an intrinsic property of most organic matter, at least as observed in the laboratory. It can be driven only by an external source of free energy that is coupled to the organic system.

      Page 60

      quote :

      In water, the assembly of nucleosides from component sugars and nucleobases, the assembly of nucleotides from nucleosides and phosphate, and the assembly of oligonucleotides from nucleotides are all thermodynamically uphill in water.
      That is also true for polypeptide chains that join amino acids. Two amino acids do not spontaneously join in water. Rather, the opposite reaction is thermodynamically favored at any plausible concentrations: polypeptide chains spontaneously hydrolyze in water, yielding their constituent amino acids.

      my emphasis

      There is a lot of good and honest science being put forward here.
      What is it telling us?

      Firstly — There is no “plausible” route to complex biomolecules.

      Secondly — An external source of free energy is needed to form these compounds.
      In other words some outside agency is required.

      Thirdly — Clearly in water, either thermodynamically or chemically, biomolecules whether they are nucleotides or oligonucleotides or amino acids chains, cannot form spontaneously.

      Yet Darwin and many others, like Stanley Miller and Harold Urey and many others have all posited and indeed continue to try to show that life could have spontaneously originated in water.
      All this in spite of science being against them.

      When I have said that these hypotheses have no bases in science, even NASA agrees with me.

      The cell had to predate the protein, there is no way around this in science.
      Philosophically, one may wish to hypothesize chemical processes that lead up to the formation of a cell, but scientifically they are implausible.

      As NASA research has confirmed, an outside agency is required.

    • #105982
      canalon
      Participant

      Too much spammers, not enough mods, will come back to you later….

    • #106060
      scottie
      Participant

      Origin of Life.
      Since no one is prepared to reveal what is their understanding of the processes that cause speciation other than simply state that, “evolution is a fact”,
      I will try and describe my understanding of what the consensus opinion appears to be.

      Firstly
      How can Life be defined?

      Here is a definition

      Life is a system of chemicals that possess functional information (i.e.knowledge) in their molecules and a mechanism to implement that knowledge in such a way that the system can survive and replicate itself.

      My understanding of the Molecular theory of evolution

      Sections of DNA store information needed to make proteins. This is functional information (knowledge) and this is what constitutes a gene.
      This knowledge is passed from generation to generation by a process of replication.
      Chance or random errors during replication or other causes, create the potential to make new genes.
      These mutations may create new information or alter existing information.
      In either case nature preserves the beneficial mutations ( i.e. the knowledge to modify or make new proteins) by the process of natural selection, while the other mutations survive only by chance.
      Over millions of years changes in existing genes result in new genes and that is the way animals adapt and evolve.

      The problem with this framework is that if an existing gene evolves into a new gene with a new function then the old function will be lost.
      Natural selection however will not allow that to happen, for obvious reasons.

      So it was hypothesised that existing genes do not evolve into new genes unless the first gene is duplicated.
      This duplicate copy is now free to evolve while the first maintains its function.
      This theory has since been refined by further suggesting that pieces of genes may be duplicated and then rearranged to create new genes with new functions.

      This is the theory that essentially explains the origin of many genes.

      Remember all these mutations are chance (random)mutations that can only be filtered by natural selection if they have function, (i.e. they produce protein.)

      Natural selection cannot act on any stretch of DNA unless it has a function that has produced a protein

      Also remember that the cell is presumed to be in existence for this hypothesis to even get started.

      Also this process is blind and has no foresight.

      So the origin of the cell is unanswered and as we are now discovering there are no natural plausible pathways to the production of complex biochemical molecules.

      What does that leave us with?

    • #106065
      canalon
      Participant

      I like that last post.
      At least it makes clear what we can agree and disagree on.
      Basically you got the gist of how genes do evolve, change multiply. I just would like to add that gene duplictaion is not the only way to create new genes. So genes can be fully acquired from another organism (but it need to have evolved there) by horizontal gene transfer, and some genes that become useless because e.g. the environment changed are not the subject of selective pressure and can evolve in interesting new ways.
      Plus there are genes that affect the regulation, the expression or even the folding of the protein. All that can drastically affect survival in certain conditions.
      But I digress, you seem to accept that all that is convincingly proved and that it can happen. Am I right?

      So your biggest problem is not how can the information multiply and change over time, it is only it can appear in the first place. Your problem is not with evolutionper se, but with the creation of life.
      In which case Genesis 1 (I checked, it is in the first chapter, and you were right there is only one version of the creation of life on the earth, the 2 different stories in genesis 1 and 2 are about the creation of man), is not massively helpful either because it just tell us that it is so because of the word of god. Hmmmm…
      The science of the creation of life is much more complicated than that of the following evolution for a simple reason. Whatever the first self replicating organisms, or more likely molecules (Science’s best bet is currently self replicating RNAs with catalytic activity, as those things can be observed), they did not leave traces to be analyzed, so it is as much a game of conjectures based on the current observed outcome and what we know about the primitive atmosphere’s (and there is guesswork there) composition and conditions. A few hypothesis have been offered, but since the conditions are hard to replicate (who has a set of empty planets at the right position and a few billion years to observe the outcome? And even more importantly the funding to run the experiment? :D) it will probably stay at least very informed guesses at best.
      But they are based on observation and fact. The problem with assuming a creator are multiple and honestly strong enough to make the hypothesis quite implausible. I will refer you to the very nicely written open letter of R. Dawkins to the Gov. Perry. because he writes so much better than I do:

      quote R. Dawkins:

      Darwin explained all of this with one brilliantly simple idea – natural selection, driving gradual evolution over immensities of geological time. His is a good theory because of the huge ratio of what it explains (all the complexity of life) divided by what it needs to assume (simply the nonrandom survival of hereditary information through many generations). The rival theory to explain the functional complexity of life – creationism – is about as bad a theory as has ever been proposed. What it postulates (an intelligent designer) is even more complex, even more statistically improbable than what it explains.

      In my word: If one assume that information cannot arise spontaneously, which is what you do, then we have to assume that an original agent created the self replicating information. But that leave us with the problem of the origin of this first agent. It is just like panspermia, life may not have originated on earth (makes the game of informed guesses about the condition for the origin of life even more complicated), but the process for its creation somewhere else must have followed the same general rules. It is just moving the problem without providing any new information. So pray tell me, where does the original agent come from?
      This is not science, this is logic. In science when you are making an argument you have to demonstrate that it holds water. You can spend hours on the rest if your foundation is leaky, however beautifully crafted and built is the rest of the edifice, it will crash down. So will you finally answer my simple question? As long as you cannot even provide any clue, speculation or whatever beginning of information about that, all the rest is just wind. If you keep posting your long winded diatribes and ignoring that little fact, I will have to assume that there is no point in having a discussion with you. So, once again and very clearly:
      Where does the original agent come from?

    • #106068
      scottie
      Participant

      Thanks for your post

      I have got to go out this evening so will respond first thing tomorrow morning.

      thanks

    • #106084
      scottie
      Participant

      May I deal with your response one at a time, as all you that have written is definitely worthy of a response.

      quote :

      I like that last post.
      At least it makes clear what we can agree and disagree on.
      Basically you got the gist of how genes do evolve, change multiply. I just would like to add that gene duplictaion is not the only way to create new genes. So genes can be fully acquired from another organism (but it need to have evolved there) by horizontal gene transfer, and some genes that become useless because e.g. the environment changed are not the subject of selective pressure and can evolve in interesting new ways.
      Plus there are genes that affect the regulation, the expression or even the folding of the protein. All that can drastically affect survival in certain conditions.
      But I digress, you seem to accept that all that is convincingly proved and that it can happen.
      Am I right?

      Well no, not quite.

      If you will recall I have made repeated attempts to get someone to posit their understanding of what “evolution” actually is.
      That ended in failure so I posited my understanding of what is generally understood and of course centred that understanding specifically around molecular evolution.

      The principle behind the idea of gene duplication is to account for how a new function can arise without the loss of the old function, which natural selection (the central concept of Darwinian theory) would prevent.
      Natural selection can only select from an existing function. It does not create new functions.
      In other words Natural Selection can account for the demise of a species not the arrival of a species.

      Therefore another “gene(s)” however arrived at would be needed and free to evolve.

      The central question though is whether these theories or hypotheses can account for the arrival of new species (i.e. new body plans.)

      So lets examine what the science is behind these hypotheses.

      Gene duplication, does it occur?
      Yes it does
      http://onlinelibrary.wiley.com/doi/10.1 … 3/abstract

      Spontaneous duplication of the mammalian genome occurs in approximately 1% of fertilizations. Although one or more whole genome duplications are believed to have influenced vertebrate evolution, polyploidy of contemporary mammals is generally incompatible with normal development and function of all but a few tissues.
      (My emphasis)

      There is of course a lot more information that highly questions that gene duplication can account for speciation and if required I will provide the evidence.

      HGT is posited as another method by which natural selection would be allowed to operate.
      Does it occur.
      Well yes again, in bacteria and unicellular eukaryotes.
      http://jxb.oxfordjournals.org/content/58/1/1

      quote :

      However, the prevalence and importance of HGT in the evolution of multicellular eukaryotes remain unclear.

      And again I can provide a lot more information as evidence, but at best these ideas are definitely questionable when it comes to explaining origin of speciation.

      This is why there are so many ideas that try to explain speciation with some directly contradicting Darwinism, Evo Devo and Symbiotic theory are but two of them.

      quote :

      So your biggest problem is not how can the information multiply and change over time, it is only it can appear in the first place. Your problem is not with evolutionper se, but with the creation of life.

      Ii is not me that has a problem. It is the many scientists (not science) trying to explain these matters that have the problem.

      Now I will end this post here to allow a response to this particular part and will respond to your other points shortly.

    • #106090
      scottie
      Participant

      Patrick
      Ok lets continue, this is a long one but you have raised quite a few points

      quote :

      In which case Genesis 1 (I checked, it is in the first chapter, and you were right there is only one version of the creation of life on the earth, the 2 different stories in genesis 1 and 2 are about the creation of man), is not massively helpful either because it just tell us that it is so because of the word of god. Hmmmm…

      It’s nice to see you have at least done some homework and agree with me on the number of creation accounts.
      However please read the account more carefully.
      1) The second is not about the creation of man, it is about the start of his history.
      The creation of man (male and female) appears in the first history. Chap 1:27
      You do yourself no justice when you make such careless errors in the simple matter of reading accurately.
      2) Where does the account state it is the word of God ?
      Your bias is blinding you to what is actually being stated.

      This account claims to be a history set down by ancients. The only question that can be attributed to it is whether it is accurate. That’s all.

      quote :

      Science’s best bet is currently self replicating RNAs with catalytic activity, as those things can be observed

      Really?
      Leslie Orgel’s posthumous essay on this subject is worthy of note.
      Remember he was one of the originators of the RNA world hypothesis.

      Now please read his paper of 2007 and note his conclusion of his own hypothesis which you will find here.
      It is entitled
      The Implausibility of Metabolic Cycles on the Prebiotic Earth
      http://www.plosbiology.org/article/info … io.0060018

      And here is his concluding comment

      "However, solutions offered by supporters of geneticist or metabolist scenarios that are dependent on “if pigs could fly” hypothetical chemistry are unlikely to help."

      The above is not the conclusion of some lone scientist because there are many.

      Remember I informed you of the conclusion NASA itself had reluctantly arrived at.
      There are no natural plausible pathways to the production of complex biochemical molecules.

      You see science knows that pigs don’t fly.

      You would do well to research your belief system properly rather than running with “pigs will fly” hypotheses and then treat them as if they constitute science.

      Now we already know that water prohibits any peptide sequences from forming.
      They are both chemically and thermodynamically implausible.
      This is a scientific fact.
      So what would be a better place to get started?
      Well, instead of water how about earth.

      You know those ancients were indeed quite clever chaps..
      Just look at what they wrote about the first forms of life.
      And the earth began to put forth grass, vegetation bearing seed according to its kind and trees yielding fruit, the seed of which is in it according to its kind……"

      So far then, this account has been shown to be correct in that originally, all the land mass was in one place.

      Those ancients clearly knew something that has taken modern science quite a little while to catch up with, me thinks
      Certainly contrasts with Darwin’s musings of “quiet little pond” somewhere. 🙂

      Now we note that they even knew where life got started and you appear to be still struggling to catch up.

      OK lets take a third
      There is a biologic logic about the first forms of life being vegetation.
      After all they manufacture their own food in order to survive.

      The account then goes on to state that life then got going in the seas and atmosphere and then the animals of the land.

      Scientifically implausible or scientifically plausible?

      Remember this is just an historical account. It’s not a scientific document.

      OK lets take Dawkins little open letter to Rick Perry.
      I don’t know much about this Perry person other than I think he considers himself suitable to run for the presidency of the US.
      However I do know a little something about this Richard Dawkins fellow.

      He is the eminent scientist who hypothesized the “selfish gene concept”
      That turned out to be wrong. Strike 1.
      He is still stuck in his “gradual evolution” mindset.
      Again we have science turning against him. Strike 2
      What about his Tree of Life mindset?
      Now you ought to know all about this, what with HGT and all. Have a chat with Carl Woese.et al.
      So that is also turning against him — Strike 3

      Was it not Mayor Rudy Giuliani who came up with the 3 strikes and you are out policy.
      Of course the scientific community are a little more tolerant 🙂

      A little bit of advice, if you must quote him do it on his religion not on his science.

      Now this is quite a “long winded” post as you keep reminding me so I had better end it here.
      I will deal with your next point tomorrow.
      Trust me I will answer your question 🙂

    • #106122
      scottie
      Participant

      Patrick
      Sorry for the delay.
      As I understand it your argument is essentially this.
      So long as the originator cannot be named or identified then that is evidence the originator doesn’t exist.
      Therefore (according to your logic Gravity doesn’t exist, The Laws of motion do not exist and as we don’t know who invented the wheel so it doesn’t exist either etc etc.)

      Now of course this is nonsense, as you well know, and we have covered this point before.

      However I have noticed that you have changed your approach somewhat.

      You previously wanted to know the name of the originator.(agent)
      It has now changed to

      quote :

      “So pray tell me, where does the original agent come from?

      Look I don’t need to pray about this.
      Be that as it may, lets deal with your comment on information.
      We know, because science has established it, that the metabolic pathways we observe in the cell do not exist in natural law.

      Natural laws that the study of science rests on, are not observed in the functional information content we observe guiding cell processes. That I assume is clear enough to you, since you have not attempted to rebut any of the information I have provided.

      Therefore that guiding information can only come from an outside agency as I keep stressing.
      Now you may not have realised the fact that information is non material.
      The chemical molecules are material but the information they contain, that directs them in ways that are not linear and in non random ways, is not material.

      Why else does the cell enlist such elaborate editing and feedback looping that we observe. Also we are now observing the tremendous redundancy that exists ensuring constancy of functional output.

      All our experience tells us that this king of information comes from a mind, one that is using “ an external source of free energy” as NASA puts it.

      This is the only evidence we have and all that evidence is staring at us, inconveniently it appears to some or indeed many.

      So why is it so difficult to grasp such a simple concept?

      There can only be one reason.
      Your philosophy prevents you from doing so.
      Please reflect for a moment, on your own statement

      quote :

      Science’s best bet is currently self replicating RNAs with catalytic activity, as those things can be observed

      Now apart from the fact that you aren’t keeping up with the latest understanding amongst scientists, you are reducing your view of science to a casino operation.

      Scientists with certain philosophical needs may engage in betting, science however is not a casino.

      This type of wishful speculation stems from a philosophical need.
      It has nothing to do with science and deep down I suspect you know it.
      ( Freeman Dyson sums it up nicely in a conclusion comment to his own speculative scenario on origins.
      “ The question is whether any of that makes sense. I think it does, but like all models, its going to be short-lived and soon replaced by something better.”)

      One thing we are agreed upon though.
      Logic is not science. There maybe logic in studying science but in itself it is not science.
      Philosophy, parading as science however cleverly it may be dressed up, is also not science.

      At least creationists, bizarre though some of their statements may be, wear their philosophy/religion on their sleeves.
      You though, are trying to camouflage yours under the guise of science. That is not a very stable foundation.

      Now there are invariably fundamentalist diehards who despite all the evidence to the contrary will continue to stick to an idea, no matter what.
      I sincerely hope you are not one of those, but that has to be your decision.
      In the meantime however I will continue to present information in the hope of course you don’t bar me from this forum. 🙂

      Craig Venter and George Church recently had a discussion regarding the ribosome which is very revealing.

      I will copy part of the transcript in my next post, as this has gone on long enough. 🙂

    • #106124
      JackBean
      Participant
      quote scottie:

      We know, because science has established it, that the metabolic pathways we observe in the cell do not exist in natural law.

      Natural laws that the study of science rests on, are not observed in the functional information content we observe guiding cell processes. That I assume is clear enough to you, since you have not attempted to rebut any of the information I have provided.

      I have probably skip this one. Which natural laws are you talking about?

    • #106141
      canalon
      Participant

      Now Scottie, my simple question is one of logic, not science, not naming not nothing, simple logic. I will detail it one more time for your understanding:
      1- Complexity, such as observed in life, cannot arise spontaneously
      2- Ergo matter needs guidance by a complex entity to organize it self in living beings
      So what guides the matter? And how did it appear without guidance, as it would launch us in a recursive loop?

    • #106145
      LeoPol
      Participant

      Nucleic-acid-peptide micro-molecular technology – a database of DNA through RNA intermediaries is implemented by the polypeptide interface. But this is an automated production system. A user who is? And this is an older subject – glyco-lipid membrane. Once upon a time, a few billion years ago, some engineers of a great civilization glyco-lipidoides created this nucleic acid-peptide technology and armed with it, settled by a million ships in all parts of the visible universe. But what do our evolutionists? And they are the origin and evolution of life on self-replicators – RNA! Wow! So you can keep your computer from the origin of a computer mouse! Yes, the computer system, of course at the last regular duplication mice formed a small detail, like user … 😯

    • #106166
      scottie
      Participant

      JackBean » Tue Aug 30, 2011 12:51 pm

      quote :

      I have probably skip this one. Which natural laws are you talking about?

      The laws of Physics, Chemistry, Thermodynamics.

      These natural laws are not left unguided in cell processes. They are guided by the functional information contained in the cell.
      That information is not internally sourced but, as for example, NASA has concluded can only be from an outside source.

      Patrick

      quote :

      1- Complexity, such as observed in life, cannot arise spontaneously

      Correct

      quote :

      2- Ergo matter needs guidance by a complex entity to organize it self in living beings

      Correct

      quote :

      So what guides the matter? And how did it appear without guidance, as it would launch us in a recursive loop?

      As I have already stated in my last post.
      It did not appear without guidance.
      All our experience tells us that this kind of guiding information comes from a mind.
      Is there any other logic we have experience to go on?
      If so please inform.

      Leopol
      As I understand it, you have a view that life was planted here on earth by an extra-terrestrial lifeform.

      Is that correct?

    • #106177
      LeoPol
      Participant

      to Scottie
      I think the concept "extra-terrestrial" for life is not correct. Life is life. It is the same painful geo-anthropo-centrism. Intelligent life, armed with a nucleic-polypeptide technology could in a few billion years to spread widely in the universe, and here we have one of the planetary population. It is strange that you do not think this is correct!
      Another interesting question. The above is obvious, but the crowd of smart people at NASA and elsewhere raise the question only about panspermia microorganisms! Why not reasonable landings? It’s that – a taboo? I wonder who the customer? Ah yes, the theory of evolution as something is lost … And creationism, too, seemed suddenly melts away … Wow!

    • #106178
      LeoPol
      Participant

      to Scottie

      There is also the question of why intelligent life is usually unwise? But it is not difficult:

      Collapse of civilizations – the regression of creative thinking

      It is well known that in the living world all on demand and trains – is evolving and what does not on demand and no trains – regresses.

      This refers to the organs and tissues of our organism to thinking skills, communication, food and much more, but also social institutions, and large industries. And more broadly – to the development of species and entire ecological systems. "Claim" in different cases is a demand, "social order", "selection pressure" and so on. If this law of nature to apply the theory to our ability to think creatively, the result a sudden a logical conclusion, which is the very our "starting point".
      Sense reasoning is as follows:
      Creative intelligence to develop a species until it is demanded. With it, created an elaborate set of global technology standards and stereotypes in all spheres of public life. But then, after reaching a "global harmony" and a "welfare society" creative intelligence is no longer needed, subject to negative selection pressure and begins to regress.
      30-50 thousand years happy hypothetical "world empire" (or "Democracy") becomes a world of "ants" in the minds narrowly stereotypical type of mind, where a return to the creative phase is almost impossible.
      A thousand years later, 200-300 changes in genetically fixed and this species generally losing the creative intelligence, and the "purposeful activity" in this society is no different from the cooperative activity of the same social insects. This is not the mind, and his remains – a relic. Relic Paleo-civilization reasonable.
      Armed with such a logical premise, it is possible to take a fresh look at our world as something that it has featured such "relics of the Mind," left over from long ago emerged and faded manifestation of "creative intelligence."
      This is the same social insects, provided such relics of two integers: public-Hymenoptera (wasps, bees, ants), which became public, according to various sources, from some point between 50 and 100 million years ago (an ancestor – a giant wasp) and

      – Termites, which have left their public relic from a certain point in time from 120 to 200 million years ago (an ancestor – a giant cockroach).

      Can claim to be a "relic of reasonableness" and

      – Multicellularity our organisms (there was about a half billion years ago, the creator – Vendian biont large aerobic unicellular ameboid, who built a very complex civilized society – a multicellular organism Myxomycetes).
      Some terrestrial civilization can not leave behind a "relic" – coelenterates, sponges (archeocyathids), marine polychaete (trilobites), rakoskorpions, siphonophores, salps, cephalopods, and pikaias.

      Well, the question of how to achieve the welfare, thus, is a question of how to kill a civilization. 😥

      http://spacenoology.agro.name/?page_id=32
      ( http://translate.google.com/translate?s … ge_id%3D32 )

    • #106179
      JackBean
      Participant

      Can you tell, how exactly the metabolic processes are against the natural laws? Because I’m pretty sure they are not.

    • #106220
      JackBean
      Participant

      here is some nice reading 🙂
      http://www.naontiotami.com/2011/08/does … d-rebuilt/

    • #106250
      LeoPol
      Participant

      Oh, thank you, this is interesting! But our situation is better! Our version of the ID do not want creationism. 😀

    • #106297
      scottie
      Participant

      Jackbean

      Sorry for delay in responding. I have been away for a few days.

      quote :

      JackBean » Mon Sep 05, 2011 8:55 am
      Can you tell, how exactly the metabolic processes are against the natural laws? Because I’m pretty sure they are not.

      I think you misunderstand what I am saying.
      Let me try and clarify.

      The molecules involved in metabolic processes, without a guiding outside source of energy will follow the natural laws and disintegrate down to their elemental natural states.

      I have approached this subject before but I feel it is now important to revisit it again.

      Lets take the question as to what happens at death?
      In other words what is the difference between, say, a living dog and a dead one?

      At the moment of death, all the processes we have studied in biology cease and the dog begins to disintegrate.
      However that disintegrating corpse is still subject to the same laws of physics and chemistry as the live dog was, so what was keeping the live dog living?

      At the moment of death all the biochemical molecules in body are the same as when it was alive. The same functional information in the molecules remains, yet function has ceased.

      Now ask yourself what kind of logic are we appealing to which suggests, that by assembling all the molecules together (assuming we are able to of course) into the form of a dog, we will create a dog that lives, or indeed any form of living organism.

      Doesn’t all our experience, data and intuitive understanding tell us that life is something apart from mere chemical molecules?

      Life is what keeps the chemical molecules that make up our bodies from following the natural laws that send these molecules back to their constituent parts. When life is removed these molecules begin reverting back to what they were originally.

      I hope that explains my point more clearly.

      btw I am not arguing for the ID community. There are some fundamental difficulties I have with their line of argumentation.
      I will be happy to explain in more detail if called upon.

      Leopol

      Sorry but I am having great difficulty in understanding your posts.
      It maybe a language problem.

    • #106310
      TheMatrixDNA
      Participant
      quote chilipanda:

      Hey guys,

      I’m writing a paper on the origin of life, and I need some suggestions about which theories to write about. Obviously there are tons of them, so any suggestions, information, or references you guys can give me would be great.

      Hi, Chilipanda,

      What about a theory that suggests there were no origins of life in this natural Universe because it connects Cosmological Evolution to Biological Evolution? This theory is the result of comparative anatomy between the first cell system and the last non-living system, which built a model of LUCA (the last Universal Common Ancestor), a kind of building blocks of astronomic systems, the lost link between the state the world about 4 billion years ago and the first nucleotide at Earth. The theory suggests the DNA as a universal template, called The Matrix/DNA. So, it is not panspermia, only suggesting that there was a hidden variable ( the matrix ) at the primordial soup.

      Ok, I am the author of this theory which has cost to me about 30 years of hard work. As an agnostic I don’t believe in this theory but the amount of evidences and right predictions are becoming astonishing and I am testing the models. I need ideas for testing/discussing and your topic – as I am following it – is very interesting and helpful. I should be grateful if you permit to participate in this debate. At least, I can suggest faults and gaps on the existents theories that nobody else has thought about. I can do it? Cheers…

    • #106313
      TheMatrixDNA
      Participant
      quote believer:

      Everyone that has ever commented on the origins of life are reduced to their opinions, even the great Richard Dawkins is left to speculation.

      Hi, Believer,

      There is a set of natural laws and mechanisms. If you know them and follow biological evolution in the reverse way towards biological systems origins, you will be no “left to speculations”.

      Feel free for asking or pointing out when you think there are gaps.

      But, then, you will arrive at the state of the world before life’s origins, the world that created life. If you apply the same set of laws for calculating that state of the world you will get a surprising cosmological model, where Astros exists under life’s cycles and performing perfect closed systems. The blueprint of this model is a building block, identical to a nucleotide, the fundamental unit of information in the DNA. So, there was no origin of life at Earth, because Earth, itself, belongs to a system that is half-living.

      So, the right calculations using only natural laws and mechanisms you discovered that there is a link between biological evolution and the past cosmological evolution: the DNA template.

      Continuing going deep to the past, with those laws, you will arrive to the primordial nebula of atoms systems. But, then, you will have a more complex model of atoms: they have the principles of life’s properties.
      Go deepest, before the atom nebulae, and you will meet with empty vortexes. But, you will see that those vortexes have the laws, the mechanisms and all life’s properties.

      Now you are going to before the Big Bang, leaving this Universe and believing that those vortexes are bits-information, like genes, coming from a natural system, ex-machine. That could be your God. To me, it means merely more research work to do…

    • #106329
      scottie
      Participant

      As promised in a previous post, a transcript of an interesting conversation

      quote :

      This year’s Annual Edge Event took place at Eastover Farm in Bethlehem, CT on
      Monday, August 27th. Invited to address the topic “Life: What a Concept!” were
      Freeman Dyson, J. Craig Venter, George Church, Robert Shapiro, Dimitar Sasselov, and Seth Lloyd, who focused on their new, and in more than a few cases, startling research, and/or ideas in the biological sciences.

      http://www.edge.org/documents/life/Life.pdf

      You will find more information on the scientists including video clips from this event.
      http://www.edge.org/documents/life/life_index.html
      The video clip of Robert Shapiro is quite interesting.

      I would recommend spending some time reading and viewing this.

      Here is part of the transcript of the Event.
      Discussion between Venter, Church and Shapiro.

      Page 76

      quote :

      CHURCH: I’m a little more interested in the future than the past — but I don’t
      dismiss it either. For example, on the top of Freeman’s wish list was ribosome
      archaeology. And Dimitar asked, Is there a milestone that we think is significant.
      The ribosome, both looking at the past and at the future, is a very significant
      structure — it’s the most complicated thing that is present in all organisms. Craig does comparative genomics, and you find that almost the only thing that’s in common across all organisms is the ribosome. And it’s recognizable; it’s highly conserved. So the question is, how did that thing come to be? And if I were to be an intelligent design defender, that’s what I would focus on; how did the ribosome come to be?
      The only way we’re going to become good scientists and prove that it could come into being spontaneously is to develop a much better in vitro system where you can make smaller versions of the ribosome that still work, and make all kinds of variations on it to do really useful things but that are really wildly different, and so forth, and get real familiarity with this really complicated machine. Because it does a really great thing: it does this mutual information trick, but not from changing something kind of trivial, from DNA to RNA; that’s really easy. It can change from DNA three nucleotides into one amino acid. That’s really marvelous. We need to understand that better.

      VENTER: And you can’t have life without it.

      CHURCH: Definitely. It’s common to all life. We need to understand that, and the way we’re going to fund it — there’s not that much funding for prebiotic science, but if there’s a lot of funding for understanding the ribosome in the future and in the present, inevitably it will much enable studies of it in the archaeological and ancient biology sense.

      VENTER: But using these tools, it’s my hope we can do something similar to what you suggest. We can extrapolate back once we have the database of Planet Earth genes to what might have been a precursor species, and then we should be able to build that in the lab and see if it was really viable, and then start to do component mixtures to see if you can spontaneously generate such things.

      CHURCH: But isn’t it the case that, if we take all the life forms we have so far, isn’t the minimum for the ribosome about 53 proteins and 3 polynucleotides? And hasn’t that kind of already reached a plateau where adding more genomes doesn’t reduce that number of proteins?

      VENTER: Below ribosomes, yes: you certainly can’t get below that. But you have to have self-replication.

      CHURCH: But that’s what we need to do — otherwise they’ll call it irreducible complexity. If you say you can’t get below a ribosome, we’re in trouble, right? We have to find a ribosome that can do its trick with less than 53 proteins.

      VENTER: In the RNA world, you didn’t need ribosomes.

      CHURCH: But we need to construct that. Nobody has constructed a ribosome that works well without proteins.

      VENTER: Yes.

      SHAPIRO: I can only suggest that a ribosome forming spontaneously has about the same probability as an eye forming spontaneously.

      CHURCH: It won’t form spontaneously; we’ll do it bit by bit.

      SHAPIRO: Both are obviously products of long evolution of preexisting life through the process of trial and error.

      CHURCH: But none of us has recreated that any.

      SHAPIRO: There must have been much more primitive ways of putting together catalysts.

      CHURCH: But prove it.

      Notice how both Church and Venter agree that the ribosome has no precursor, in fact Church recommends that the ribosome is the candidate for the ID community to concentrate on as an example of irreducible complexity.

      So the evidence is quite clear to these scientists, but note Shapiro’s interjection

      quote :

      Both are obviously products of long evolution of preexisting life through the process of trial and error.

      Here you have an obvious example of a renowned scientist whose thinking is guided by his philosophical view rather than by evidence.

    • #106334
      LeoPol
      Participant

      scottie
      I decided to speak out on three topic at Dawkins. But controversy still slightly opened only on one: http://richarddawkins.net/discussions/6 … ure?page=1 .
      The other two – Brake.
      ( – http://richarddawkins.net/discussions/5 … FrIJIB6U8g
      http://richarddawkins.net/discussions/6 … ife?page=4 )
      Is there a bad translation and turned out? I tried so hard! 😯

    • #106352
      scottie
      Participant

      Leopol

      There clearly is a problem in translating from Russian and it does make understanding your posts a little difficult. However you must be commended for trying.

      I have spent some time in trying to understand your position, so let me try and respond to your view.

      As I am beginning to understand it, you use the expression

      quote :

      Nucleic-acid-peptide micro-molecular technology

      In other words it seems to me that you appear believe that a technology has been developed in the past whereby peptide chains could be produced, thereby providing the ability to make cellular life.
      This technology has been transferred to the earth and that accounts for our present condition.

      I think you agree that this view is highly speculative, but more than that I believe you are making the same basic mistake that evolutionary theory an indeed ID theory make, that is, the appearance of life has been through a bottom up process.

      In other words you start with basic building blocks ( pre-biotic and then biotic) and then build up the whole organism, this essentially summarises the evolutionary view.
      The ID view ( as I understand it) has a similar perspective in that the designer has built up the organism in a Lego-like assembly way.

      However this does not reflect what we observe in reality.
      Let me try and explain with an example.

      We tend to see the cytoskeleton portrayed as a fixed structure,
      But that is simply incorrect

      quote :

      “ … it is not a fixed structure whose function can be understood in isolation. Rather it is a dynamic and adaptive structure whose component polymers and regulatory proteins are in constant flux.”

      Cell Mechanics and the Cytoskeleton – Nature 463 Jan 28 2010 485-492)

      The cell is typically about 80% water and when examined we note that the main activity is a pattern of flows. What we see are fixed structures that actually are part of these flows.

      Craig Holdrege in his book “ The dynamic Heart and Circulation” describes the development of the heart this way
      http://www.natureinstitute.org/pub/ic/ic7/heart.htm

      quote :

      We see that blood flow, the form of the heart, the pattern of its fibers, and the motion of the heartbeat are intimately entwined. We can’t think of one without the others. When we go back to the origin of the blood and the heart in embryonic development, it is no simple matter to say what came first. Early in its development the heart begins to form loops that redirect blood flow. But before the heart has developed walls (septa) separating the four chambers from each other, the blood already flows in two distinct "currents" through the heart. The blood flowing through the right and left sides of the heart do not mix, but stream and loop past each other, just as two currents in a body of water. In the “still water zone” between the two currents, the septum dividing the two chambers forms [1]. Thus the movement of the blood shapes the heart, just as the looping heart redirects the flow of blood.

      We have been educated to see the living organism as an assembly of individual parts,for example like a watch that is put together in a certain way.

      However in a living organism, (as one writer puts it)

      quote :

      the parts grow within an integral unity from the very start. They do not add themselves together to form a whole, but rather differentiate themselves out of a prior wholeness… They are growing even as they begin functioning, and their functioning is a contribution to their growing. The parts never were and never are separate, never assembled.

      Both the evolutionary and ID views have this common foundation. They have a bottom up perspective of living organisms, when in fact the reverse is the case.
      It is the whole that determines the parts. This whole is determined from the moment the two gamete cells join to form the Zygote.

      It is this wholeness that scientists have not been able to come to terms with, and the result has been a fruitless search for some understanding as to how these parts could have come together to form the whole we see and indeed are.

      Chemical molecules do not come together to form life.
      Even cutting edge biologists such a Craig Venter and George Church are beginning to recognise this fact.
      (The little transcript of their conversation at the Edge event that I had in my last post reveals this)
      They are only one step removed from recognising that life uses chemical molecules to persist. When life ends these molecules revert back to their constituent parts.

      We know of no instance where life has come from any source other than another life.
      To try and show that it can and indeed has is no different than looking for fairies at the bottom of some garden.

    • #106353
      JackBean
      Participant

      No, Venter says, that the precursor is from RNA world, but since we don’t have no such ribosomes nowadays (w/o proteins), we cannot reduce the number of proteins to less than 53.

    • #106354
      JackBean
      Participant
      quote scottie:

      Lets take the question as to what happens at death?
      In other words what is the difference between, say, a living dog and a dead one?

      Ahh, you mean this…
      The molecules are still the same, they are just not regulated. Even the cells do not die immediately after death, but they survive a little, although they are not synchronized anymore and of course, the shortage of supply causes their death later. This was discussed in another topic recently.

      quote scottie:

      btw I am not arguing for the ID community. There are some fundamental difficulties I have with their line of argumentation.
      I will be happy to explain in more detail if called upon.

      Please, go on.

    • #106368
      LeoPol
      Participant

      scottie
      Thank you! 😀
      The hypothesis is that the cell membrane – this is a direct descendant of the brilliant engineers who have several billion years ago created "Nucleic-acid-peptide micro-molecular technology". That’s membrane and is the carrier of "consciousness" – what we call ‘I’. Everything else – equipment.
      You can say so, that in every cell membrane formed a kind of cellular "self", which is the "active model of the world in an electromagnetic field of the membrane."

      I must add that this hypothesis is very useful in molecular biology, because it creates a theoretical model of cell entity which manages all the cellular technologies. A lot gets new meaning clear! At least, now we need to look for those instructions that guided this subject!

    • #106369
      scottie
      Participant

      Jackbean

      Thanks for your response.
      May I deal with your points in turn for fear my post will get too long, something for which in the past I plead guilty. 🙂

      quote :

      No, Venter says, that the precursor is from RNA world, but since we don’t have no such ribosomes nowadays (w/o proteins), we cannot reduce the number of proteins to less than 53.

      Firstly please note what he previously said about the ribosome

      quote :

      And you can’t have life without it.

      Also what Venter actually then said was this

      quote :

      In the RNA world, you didn’t need ribosomes.

      The RNA world is a speculative scenario that many are clinging to in order to have some hope of progress. However even Venter knows that is a speculative hope. He probably was not aware at that time of the NASA report (I have referred to it previously) which stated quite clearly that there are no plausible hypothesis for routes to complex biochemical molecules, either chemically or thermodynamically.

      So probably not even being aware of the NASA conclusion at that time he remained in the speculative world of RNA

      Now if you wish to remain there as well, then that’s OK it’s your choice, but please, remember that science is not backing you up.

      Now on the question of organism death you responded

      quote :

      Ahh, you mean this…
      The molecules are still the same, they are just not regulated. Even the cells do not die immediately after death, but they survive a little, although they are not synchronized anymore and of course, the shortage of supply causes their death later. This was discussed in another topic recently.

      You are right we have discussed this before, and forgive me when I state that I feel you may not have quite grasped the point I was making.

      At the moment just prior to death all the biochemical molecules in the dog are still functioning and intact.
      At the very moment of death they are still there, however as you rightly point out the regulatory mechanisms cease and the molecules begin to disintegrate.

      In other words, the natural laws of physics, chemistry and thermodynamics continue operating but without the guiding regulation that has now been removed, and the result is degeneration, down to their constituent parts.

      Therefore the natural course that natural laws take, breakdown biochemical molecules.
      Since that is the case how can those same laws naturally guide the building of cellular life let alone the whole organisms
      They have to be guided down the different regulated pathways if they are to succeed.
      So whatever life is, it is certainly not a constituent part of physics or chemistry.

      That is why a naturalist view of the origin of life is scientifically untenable.

      That is also why NASA has been forced to draw the conclusion it has.

      If any organisation needed a natural explanation to life’s origin it is they.Just think of all the funding they would receive if they could. There is every incentive for them to prove that they have conquered the problem of Abiogenesis, and if they were able to then I will let you speculate on the news headlines!!

      One further point to note.
      Nobody has been able to describe what life actually is.
      There are many who have tried to define it in one way or another, but there is no consensus even on this basic point.

      One rather cute tribal description is :-
      “Anything that is capable of Darwinian evolution”. 🙂

      I will deal with the ID situation very shortly in the next post.

    • #106371
      scottie
      Participant

      Here are problems I have with Intelligent Design theorists.
      This is what they have to say.
      http://www.intelligentdesign.org/faq.php

      quote :

      Is intelligent design theory incompatible with evolution?
      It depends on what one means by the word “evolution.” If one simply means “change over time,” or even that living things are related by common ancestry, then there is no inherent conflict between evolutionary theory and intelligent design theory. However, the dominant theory of evolution today is neo-Darwinism, which contends that evolution is driven by natural selection acting on random mutations, an unpredictable and purposeless process that “has no discernable direction or goal, including survival of a species.” (NABT Statement on Teaching Evolution). It is this specific claim made by neo-Darwinism that intelligent design theory directly challenges.

      There appears to be a contradiction in the above statement.

      A fundamental doctrine of Darwinism is the principle of common decent/ancestry, and yet some adherents of ID ( Michael Behe for example) endorses this principle of common ancestry.

      If there is common ancestry then there has to be a mechanism that engenders this process. I have not seen that explained anywhere. Darwin explained his mechanism.

      Also, by way of an example, why would a designer tie a human being to an ape through common ancestry.?
      Why not make each separately?

      It seems to me that some of the ID community are facing both ways. I have tried to find an explanation as to how this is not a contradiction but have been unable to as yet. Maybe some one will be able to enlighten me.

      However there is a more fundamental problem in which ID is explained.
      Perhaps I could illustrate it this way.

      If I am to design a house, I don’t start with designing certain aspects of it say, the kitchen sink, then the bathroom mirror or bedrooms etc and then try and fit them all together to provide an overall framework.
      In other words I don’t start from the bottom and work upwards.
      This is how evolutionary theory is explained. (i.e. a bottom up approach)

      Design however implies purpose. Therefore it is a top down action.
      So, to try and explain design as ID proponents do in finding structures within an organism that are, for example irreducibly complex and then stating that this is evidence of Intelligent design is not sufficient.
      A living organism is more than the sum of all it parts.

      Also they appear to present a mechanistic view of organisms, a sort of sum total of biological machines.
      The very icon of the ID community is presented as an outboard motor. (the bacterial flagellum).

      When something is designed, there is always a purpose to the design.
      The various parts that go into that design always grow out of that purpose.

      Now I don’t see the ID community addressing this anywhere in their literature. In fact they appear to concentrate on simply refuting neo Darwinism.

      Actually there is nothing wrong in presenting evidence that corrects a wrong idea.
      I myself can be successfully accused of that.
      Certainly the work they do is very informative and I have learned a lot from them as indeed I have from the evolutionary community.

      However there is no apparent attempt to replace that idea (neo Darwinism) with another that demonstrates purpose.

      They are shying away from the obvious implications of what design means.

    • #106405
      scottie
      Participant

      Continuing on with the problem ID has not addressed.

      As I stated in my last post.

      quote :

      They are shying away from the obvious implications of what design means.

      Design is always the product of a purpose the Designer has in mind.
      If, as do the ID community, argue for Intelligent design, then they must reveal their understanding of the purpose of the design.

      As I see matters this is very important because they are against a theory that posits randomness without purpose and they are arguing the exact opposite.

      Now the evolutionists cite as their frame of reference Darwin’s Origin of Species (albeit with modifications, but with the central tenet intact).
      That is their narrative.

      Why can’t (or wont) the ID adherents narrate their own frame of reference?

      They need to bite the bullet on this issue.

      If they believe in the veracity of the scientific method, as indeed I do, then they should simply follow that method. Here is a good description of the scientific method.
      http://teacher.pas.rochester.edu/phy_la … ndixe.html

      As far as I am aware this forum has presented a few hypothesis
      (1) There is of course the Darwinian narrative (with all it’s epicycles)
      (2) Then there is the Creation narrative (with all it’s misunderstandings and bias read into the genesis account)
      (3) Then there is Leopol’s Nucleic-acid-peptide molecular technology.
      (4) Then there is also the genesis historical account itself (without any bias attachment)
      (5) Finally there is Intelligent Design, without a purposeful narrative.

      My question is simple.
      Is there another narrative and if not,
      Which of these accounts is most consistent with the scientific method?

    • #106425
      TheMatrixDNA
      Participant

      Scottie,

      I can’t understand how works the thoughts of all of you that search the answers for life’s existence. If you could explain to me, should be very grateful.

      Let’s go start with this:

      There are enough evidences pointing to a common ancestral. The debate now between evolutionists and iD is:
      – Is evolution an unpredictable and purposeless process that "has no discernable direction or goal, including survival of a species; or
      – Evolution is a process under design and purpose?

      Ok. How my thoughts have worked? I am at the middle of evolution process. I am inside the process. So, remembering the Gödel’s theorem, it is impossible to whom is inside a system, to know the thru about that system. I never will know the thru about evolution. No way. First of all, the evolution we are watching in the whole Universe, can be merely phases of a universal process of reproduction. Then, nobody can say scientifically that there is evolution.
      But…

      There is a natural process of evolution that is outside of me, I am bigger than it, and I can watch it, fully. And this sample of evolution obeys the evidences for evolution: it is triggered by a common ancestral.
      What is it?
      The origins and development of a human body. Everything is equal to Darwinian mechanism of evolution: natural selection, variation, inheritance, common ancestral.
      The common ancestral is a genome. The body in formation takes several different shapes (see Haeckel’s recapitulation Theory). The environment plus the forces inside the fetus sets the selection and fix shapes in the evolutionary tree.
      The genome is the common ancestry. But it came from the parents; they designed the purpose of that evolution towards a final determined forma: the human shape. This evolution process I am seeing has no purpose of a final design in the image of the common ancestor, but an image beyond it.

      At this point you are saying: “Wait! You can’t make this comparison. Everything is different…”
      And I will ask: “I said that the final meaning is the same, since that the basic postulates are the same. What is different?”
      Maybe you will not answer this question or at least will say: Louis this is such an absurd that I will not waste my time with it.
      And I will comment: “My friend, the modern human kind are living in a such artificial world, with the brain hard-wired by too many scientific fantasies, that it cannot think anymore as a natural being. Why not apply Ockham’s Razor over this question? If we have a real and natural fact under ours eyes, why appellate to imaginary constructions?

      I am not saying that my method suggests the common ancestor was made by an intelligent designer, neither that there is a God. My method suggests that the common ancestor was not a microscope initial life form. It was the astronomic system surrounding us, but, then, I have a theoretical cosmological model that fits as the common ancestor, different form the theoretical cosmological model that you have seen.

      Why not trying to think out of the box, pointing out what is different between these two processes of evolution?

    • #106441
      scottie
      Participant

      TheMatrixDNA

      Thanks for your response.
      I am a bit tied up at the moment but will respond as best as I can tomorrow.

      I will make one observation on your comment below.

      quote :

      There are enough evidences pointing to a common ancestral. The debate now between evolutionists and iD is:
      – Is evolution an unpredictable and purposeless process that “has no discernable direction or goal, including survival of a species; or
      – Evolution is a process under design and purpose?

      The problem with your statement is that the ID proponents argue that common ancestry is also evidence of a common designer.
      In other words the evidence that can be argued to suggest common ancestry also could support the common designer view.

      I however do not share the view that some ID proponents take on this matter for one simple reason. The evidence from science does not support it.

      I will summarise the evidence more fully tomorrow.

      Thanks.

    • #106443
      LeoPol
      Participant

      I adhere to the hypothesis that the engineering design occurred during the rare periods when the developed technological civilizations. This has happened very rarely. But for a very long interim periods ran the Darwin’s Natural Selection, as well as Dawkins’s His Majesty the Selfish Gene! At the same time created by the engineering design technologies were degenerative effects of natural selection. As a result of species to varying degrees, lose universalism, but due to hypertrophy of various technological relics specialize in different biological niches. It is Macro-devolution!

      Now – the arguments. Nucleic-acid-peptide molecular technology we have already considered. And now – eyes.

      With all the great variety of eye, inducers that control tab in the ontogeny of the eye are the same for all studied taxa, including vertebrates and jellyfish. Moreover, the settlement and the time of appearance of the first sample of the inductor – Vendian.
      http://www.pnas.org/content/early/2010/07/14/1008389107

      These eyes have a lens with a jellyfish: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825319/

      And also Turbellaria: http://ru.wikipedia.org/wiki/Ресничные_черви

      In polychaetes: http://www.liveinternet.ru/showjournal. … id=1022068

      Etc.

      Further. Human embryo at an early stage has gills, caudal fin … But he can not use them. This is because genetic technology support was lost when the larva was in the placenta. Or in the egg. Macro-devolution is irreversible! But now, the frogs have a larva with gills and tail fin! They are versatile us. A Turbellaria, some species of which contemporaries and now have eyes with lenses, the brain is orthogonal to type, the organ of equilibrium, etc., they are active predators! – Some Turbellaria are also free-living Müller’s larva! Hence, their ancestors – in Vendian! They still have more versatile! Give Turbellaria such a trifle as a skeleton – and it is no easier to us.

      So, Turbellaria in Vendian – a super-versatile creature. And before Turbellaria? Myxomycetes! According to the logic – even more versatile! ..

      This is a message in Russian: http://spacenoology.agro.name/?page_id=5440

    • #106445
      scottie
      Participant

      TheMatrixDNA

      There is a backdrop revealed by science that should not be ignored.
      It is therefore important to nail down a few of these scientific facts that relate to biology.
      This helps recognise any philosophical statements that may be presented as fact.

      Fact 1
      The smallest living organism (species) is a single cell bacteria or archaea. Nothing smaller than this cell is considered to be living. The constituent parts of the cell if removed from it are inert. (DNA, RNA, Proteins etc are all inert when outside the cell.)
      http://publications.nigms.nih.gov/insid … eface.html

      So what does this mean?
      Simply that any discussion on the origin of species is by definition a discussion about the origin of life itself.

      Fact 2
      There are no plausible biochemical pathways to the origin of complex biochemical molecules.
      I have already provided sufficient scientific references to this effect.
      See my post of by scottie » Fri Aug 19, 2011 12:31 pm
      about14351-180.html

      Any hypothesis has to account for this fact.

      Fact 3 on the Origin of the Genetic Code
      There is no natural explanation for the origin of the code, even in principle.
      Koonin et al concludes this way.

      quote :

      At the heart of this problem, is a dreary vicious circle: what would be the selective force behind the evolution of the extremely complex translation system before there were functional proteins? And, of course, there could be no proteins without a sufficiently effective translation system. A variety of hypotheses have been proposed in attempts to break the circle (see (133–136) and references therein) but so far none of these seems to be sufficiently coherent or enjoys sufficient support to claim the status of a real theory.

      Summarizing the state of the art in the study of the code evolution, we cannot escape considerable skepticism. It seems that the two-pronged fundamental question: “why is the genetic code the way it is and how did it come to be?,” that was asked over 50 years ago, at the dawn of molecular biology, might remain pertinent even in another 50 years. Our consolation is that we cannot think of a more fundamental problem in biology.

      http://onlinelibrary.wiley.com/doi/10.1002/iub.146/full
      Again unless any hypothesis deals with this fundamental question, all else is simply philosophy.

      Fact 4
      Life is only known to come from another life. This fact has been known and indeed proved since Darwin’s day

      Fact 5
      Evolution is a historical narrative based on the Darwinian principle

      The National Center for Biotechnology Information (NCBI) has an online book entitled
      Molecular Cell Biology. 4th edition.
      Lodish H, Berk A, Zipursky SL, et al. 2000

      It is an excellent reference point in understanding cell biology functions.
      http://www.ncbi.nlm.nih.gov/books/NBK21568/

      This is how it describes the subject of evolution.

      quote :

      The interplay of events played out over billions of years, in the historical process called evolution, dictates the form and structure of the living world today. Thus biology, which is the study of the results of these historical events, differs fundamentally from physics and chemistry, which deal with the essential and unchanging properties of matter.
      The great insight of Charles Darwin was that all organisms are related in a great chain of being extending from the distant past to the present. The Darwinian principle that organisms vary randomly and the fittest are then selected by the forces of their environment guides biological thinking to this day.

      Ernst Mayr (the one of the founding fathers of the Modern Synthesis) in his 1999 Crafoord pride lecture confirms his view that this is so.

      quote :

      Darwin introduced historicity into science. Evolutionary biology, in contrast with physics and chemistry, is a historical science – the evolutionist attempts to explain events and processes that have already taken place. Laws and experiments are inappropriate techniques for the explication of such events and processes. Instead one constructs a historical narrative, consisting of a tentative reconstruction of the particular scenario that led to the events one is trying to explain. (my emphasis)

      http://www.biologie.uni-hamburg.de/b-on … luence.htm
      So with these facts in mind how do the different views previously listed stand the test of the scientific method?

      Since we are in the area of an historical narrative, the acid test for any hypothesis must be whether science supports the parts of the narrative that can be tested scientifically.

      My question to you and others would be a simple one.
      Does your idea have the backing of science?
      If not it is simply a philosophical view.

      That is not a problem as there are many philosophies around. It only becomes a problem when it is presented as a scientific fact.

      So which narrative is the most scientifically plausible?

      I posit that the Genesis narrative (without the philosophical/religious bells and whistles that creationists attach to it) is the most scientifically plausible one.
      I have already put out some evidence but there is more.

    • #106446
      LeoPol
      Participant

      "The smallest living organism (species) is a single cell bacteria or archaea. Nothing smaller than this cell is considered to be living. The constituent parts of the cell if removed from it are inert. (DNA, RNA, Proteins etc are all inert when outside the cell.)
      http://publications.nigms.nih.gov/insid … eface.html"
      – This is a clear evidence that about three billion years ago, life came to Earth from elsewhere in the universe. And degraded by the laws of Devolution! So there were bacteria. And about one billion years ago, has brought back here the settlers, but the degradation was delayed … It is still going on! 😀

    • #106447
      scottie
      Participant

      Leopol

      Your idea could be the basis of a good Sci-fi movie.

      Get in touch with James Cameron.
      http://www.jamescameron.net/

      🙂

    • #106458
      LeoPol
      Participant

      Yes, exactly! The best way to describe the world of the past – sci-fi. I’m trying. Here: http://spacenoology.agro.name/?page_id=5308
      I’ve got different universal creatures from the Cambrian, Vendian and early Proterozoic in turn show a master class of his universalism. 😕

    • #106459
      LeoPol
      Participant

      Start the story here: http://spacenoology.agro.name/?page_id=4912, but a translation of Google, it’s so awful! Sorry …

    • #106465
      TheMatrixDNA
      Participant

      THE MATRIX/DNA
      Scottie
      You said:
      “The problem with your statement is that the ID proponents argue that common ancestry is also evidence of a common designer. .. I however do not share the view that some ID proponents take on this matter for one simple reason. The evidence from science does not support it.”

      And before it you said: “ I’m writing a paper on the origin of life, and I need some suggestions about which theories to write about.”

      Ok. I think you will make a critical analyze of theories. Then, you need pay attemption about the meanings of nouns and words in each theory. The word “design” is full of problems.
      You said: “Design is always the product of a purpose the Designer has in mind.”

      And Wikipedia says: “ No generally-accepted definition of “design” exists, and the term has different connotations in different fields…
      More formally, design has been defined as follows.
      (noun) a specification of an object, manifested by an agent, intended to accomplish goals, in a particular environment, using a set of primitive components, satisfying a set of requirements, subject to constraints;…”

      Now I ask you:
      – “Why “genome” is not a designer? Considering the definition above?

      I think that genome fill up every requirement cited in Wikipedia for being a designer. Wikipedia does not say that designer has something in mind , like you said, so, designer could be not something with mind. If you think that genome does not fill one requirement above, tell me.
      But, why I am talking about genome?

      The scientific evidences point out that all living things are made through genome. Is it wrong? The theory of abiogenesis says that the “first living being was made by the unanimated world”
      So ,we have a contradiction between scientific evidences and abiogenesis theory. Is it wrong?
      You said that is writing a paper about theories of origins of life. You don’t said “only known theories and theories that makes sense for you”
      Then, there is Matrix/DNA Theory, unknown, that yet does not make sense because it is too much complex and different.

      But , for instance, Matrix/DNA has no contradiction with scientific evidences. The problem of genome and the first living being is solved: the first cell system was made in a long process of million or billion years from the decay of a half-mechanical/half biological system that transmitted a half-mechanical/half biological genome, which shape ,constitution and functioning is suggested through a model.

      The non agreement between ID and Matrix/DNA is not about the word “design”, but about the word “intelligent”. The designer and design in Matrix/DNA were not intelligent.

    • #106467
      TheMatrixDNA
      Participant

      scottie

      quote :

      Fact 1
      The smallest living organism (species) is a single cell bacteria or archaea. Nothing smaller than this cell is considered to be living. The constituent parts of the cell if removed from it are inert. (DNA, RNA, Proteins etc are all inert when outside the cell.)
      http://publications.nigms.nih.gov/insid … eface.html

      Thanks by the link. But… don’t forget that the constituents party of any organism or non-living system are inert alone. The liver, the heart, the planet Earth out of solar system… etc. Separating the parts of any system is not the same of reducing the evolutionary history, or the origin, of a system. We have a problem here.

      quote :

      So what does this mean?
      Simply that any discussion on the origin of species is by definition a discussion about the origin of life itself.

      Sorry, I can’t understand your statement. The problem is again about the meaning of words. What is “origins”?

      Word English Dictionary: Origin – 1 – – A primary source; derivation 2 – the beginning of something; first stage or part( often plural ) ancestry or parentage; birth; extraction

      Then, I think, species are products of transformation, every living specie came from other living specie. In abiogenesis theory, the first cell system – aka first living being – did not came from transformation of another living system. So, I don’t think that discussion about origin of species is the same about origin of life.

      I think there is no “primary source” or “first stage “ in this Universe. I think that every evolutionist and atheist should fight this word “origins” because it commonly means that something happens coming from outside the normal natural flow of cause and effect. This word is responsible for people searching something supernatural for explaining the existence of life, the beginning of religions. But, it is the cause that some rationalists also are believing in the arisen of life by chance. The words origins and life are wrong concepts.

      The Matrix/DNA theory has solved this problem:
      It says that there was no origin of life, as the beginning of something. Every life’s properties can be find on the last most evolved system before the first cell system (as shown in the “theoretical cosmological model”. If the models are right , at Earth surface there was origins of biological system, not life. Here, living things are products of transformation also, like species. My conclusion: You are right saying that the existence of species is related to existence of life, but, then, the theory of abiogenesis is wrong.

    • #106468
      TheMatrixDNA
      Participant
      quote LeoPol:

      – This is a clear evidence that about three billion years ago, life came to Earth from elsewhere in the universe. And degraded by the laws of Devolution! So there were bacteria. And about one billion years ago, has brought back here the settlers, but the degradation was delayed … It is still going on! 😀

      Leopol

      Congratulations. I also think “that “Devolution” is a good explanation for mystery of life.

      Indeed, “life” appeared inside a system and was produced by this system that works like a watch, the Newtonian watch. But, the first living being did not work perfect like a watch, and our human body is far away from working perfect. So, only devolution explains the passage from our stellar system to the first cell system. In Matrix/DNA Theory I found a possible hypothesis for explaining this “devolutionary step”.

      LUCA, the Last Universal Common Ancestor, was not a microscope half-living thing existing at earth surface; LUCA is the building block of astronomical systems. This is where life came from. LUCA, as shown in my models, is a perfect closed system, like the Newtonian watch. But it was attacked by entropy ( what you cal laws of degradation) and reproduced with mutations here, because here we have the liquid state of matter, then, organic chemistry. But, LUCA was a closed door to evolution and biological systems are opened door, then, macro-evolution came back again, going through a different pathway.

      I think that we, both, are in the right way, with the idea of degradation. You are thinking out of the box, and this is good, you can find something new. Now, let’s go testing our theoretical models…

    • #106477
      scottie
      Participant

      TheMatrixDNA

      quote :

      “The problem with your statement is that the ID proponents argue that common ancestry is also evidence of a common designer. .. I however do not share the view that some ID proponents take on this matter for one simple reason. The evidence from science does not support it.”

      I was simply stating that ID proponents argue that way. You do not share that view.
      You say that science supports your view, they say it supports their view also.

      Fight it out among yourselves, it has nothing to do with me.

      quote :

      And before it you said: “ I’m writing a paper on the origin of life, and I need some suggestions about which theories to write about.”

      May I suggest you read what I have said and not attribute statements to me I have not made.
      I am not writing any paper nor have I requested any suggestions.

      quote :

      Now I ask you:
      – “Why “genome” is not a designer? Considering the definition above?

      I find the wikipedia defination of design quite adequate.
      As to why the genome is not a designer— well because it is the product of design that is intended to accomplish certain goals.
      If you wish to believe the genome designed itself, then go ahead and believe it.

      quote :

      But, why I am talking about genome?

      I don’t know, why are you? 🙂

      quote :

      You said that is writing a paper about theories of origins of life. You don’t said “only known theories and theories that makes sense for you”

      Once again may I remind you to attribute my statements to me, not those of someone else. May I suggest you check my postings more carefully so that you understand more clearly what I am actually writing and therefore not confuse me with anyone else.

      Am I to understand that Matrix/DNA Theory is one that you have developed?

      If it is then try and get it peer reviewed and published so that you may add credibility to your work.

      Btw the quotes you have attributed to me are from by chilipanda » Sat Sep 20, 2008 5:35 pm
      about14351.html

      Well well!!, now you have got me doing your homework for you. 🙂

    • #106478
      scottie
      Participant

      In the beginning …
      So begins the account in Genesis.( I will return to this later)

      There is also another “In the beginning..” narrative
      So goes the account in EARTH SCIENCE The Story of O2 Richard A. Kerr June 2005

      quote :

      In the beginning, Earth was devoid of oxygen, and then life arose from nonlife. As that first life evolved over a billion years, it began to produce oxygen, but not enough for the life-energizing gas to appear in the atmosphere. Was green scum all there was to life, all there ever would be? Apparently, yes, unless life and nonlife could somehow work together to oxygenate the planet from the atmosphere to the deep sea. …..
      Historians of oxygen have always agreed on one thing: Earth started out with no free oxygen–that is, diatomic oxygen, or O2. It was all tied up in rock and water. For half a century, researchers have vacillated over whether the gases that were there favored the formation of life’s starting materials (see sidebar, p. 1732). Without free oxygen, in any case, the first life that did appear by perhaps 3.5 billion years ago had to “breathe” elements such as iron, processing them to gain a mere pittance of energy.
      For decades, scientists have argued about just how long the planet remained anoxic, and thus home to nothing but tiny, simple, slow-living microorganisms. ( p 1730—1732) (it will cost you to read the entire article)

      What does chemistry tell us?

      We have rocks, made up of granite. Granite consists of different amounts of Quartz (SiO2) Feldspar of which there are three kinds (KAlSi2O2, CaAlSi2O2, and NaAl2Si2O2), and Mica (every Mica molecule contains 12 Oxygen atoms (O2).
      Limestone and Marble contain copious amounts of oxygen atoms as well.
      So there is plenty of oxygen atoms in rocks.

      Water contains oxygen (H2O)

      Now stellar evolution tells us that accretion was the process that formed the Galaxies Stars and planets. The process consists of the collision of microscopic dust (the elements) and then sticking together. Let’s assume this is correct.

      So the hypothesis is that all these, rich in Oxygen compounds, formed the rocks and water but without a remainder O2 for the atmosphere.
      What is the physics or chemistry that can confirm this? There is none.
      So why is it so emphatically stated that the early earth had no oxygen?
      Is there a reason?
      Why yes but it’s not a scientific one.

      Oxygen cannot be in the atmosphere because if it were amino acids for instance could not form. Therefore no peptide chains. If there were none of these molecules then we don’t have proteins, therefore no robosomes etc etc.
      In other words life could not begin. (the other assumption of course, is that life is simply a coming together of biological molecules in a certain way.)

      So an atmosphere devoid of oxygen has to be a given, in order for life to get
      started.

      There is no science behind this concept of no initial oxygen in the atmosphere, just speculation because of a philosophy. May I repeat.
      This “given” is a philosophical view and has nothing to do with science.

      Of course this “given” piles on even more philosophy.
      For the account then goes on. “.. and life arose from nonlife”. ( just like that!!! as a famous comedian would announce when comically doing his magic tricks)

      However, there is more to this tale, because today the atmosphere contains about 21% oxygen.

      If there was no oxygen to begin with where then did all the oxygen come from?

      Any ideas?

    • #106488
      LeoPol
      Participant

      http://ru.wikipedia.org/wiki/Европа_(спутник)

      "In the satellite (Europe) is present thin atmosphere composed mainly of oxygen."

      – And where there is oxygenation? It is also possible on Earth as it formed, as on Europe:

      "The limited surface of the atmosphere is formed by radiolysis (the decomposition of molecules by radiation) [64]. Solar ultraviolet radiation and charged particles (ions and electrons) from the face of Jupiter’s magnetosphere with the icy surface of Europa, splitting water into its components – hydrogen and oxygen. These chemical components are adsorbed and then "sprayed" into the atmosphere. Further components under the influence of the same radiation leaving the surface, and the balance of these two processes form the atmosphere [65]. Molecular oxygen – the most dense component of the atmosphere, because it has a long period of life after return to the surface it does not settle (frozen), a molecule of water or hydrogen peroxide, but, rather, again knocked out by radiation from the surface. Molecular hydrogen is never settles on the surface, leaving it as it is light enough and at such a low gravity disappears in space [66] [67]. "

    • #106492
      scottie
      Participant

      Thanks Leopol, however, how does this apply to earth?

      Without any more boring details of chemistry, the current consensus is that photosynthesis, initially from cyanobacteria produced the oxygen.

      Now it takes one CO2 molecule (Carbon Dioxide) to produce one carbon atom and one O2 (oxygen gas) molecule.

      So if there is 21% oxygen in the atmosphere now then there must have been 21% Carbon dioxide in the early earth atmosphere.

      The current carbon dioxide concentration in the atmosphere is 388.5 parts per million which 0.0388%.
      http://cdiac.esd.ornl.gov/pns/current_ghg.html

      It has been calculated that prior to the industrial revolution, around 1750 CE, the atmospheric concentration was 280 parts per million, ie 0.0337%.

      So the rise in CO2 concentration over this period amounts to 0.0051% and this rise in concentration is causing immense concern by many Climatologists, over it’s effect to life on this planet.

      What effect therefore would an atmosphere containing 21% CO2 have on life, let alone getting it started.

      The planet Venus has an atmosphere rich in CO2. Go here to examine it’s effects.
      http://eesc.columbia.edu/courses/ees/cl … earth.html
      Here is what it says

      quote :

      Venus carbon dioxide rich atmosphere creates a very strong green house effect so the planet’s surface temperature is hundreds of degrees Celsius, even with an albedo of .75. Unlike Earth, Venus has little water in its atmosphere or on its surface. Venus atmosphere does have nitrogen in fact by mass there is about as much nitrogen in the atmosphere of Venus as there is in the Earth’s atmosphere.

      So is all this hype about an early earth atmosphere being devoid of oxygen really based on science, or are these musings ( I am trying to be polite here) simply the result of a pre conceived philosophy of abiogenesis.

      The conditions that actually would destroy life are the same conditions that got life started. Does that really make any sense?

      When life began the atmosphere of the earth was essentially no different than it is today.

      Is this view scientifically plausible or implausible?

    • #106495
      arthuriandaily
      Participant
      quote chilipanda:

      Hey guys,

      I’m writing a paper on the origin of life, and I need some suggestions about which theories to write about. Obviously there are tons of them, so any suggestions, information, or references you guys can give me would be great.

      Here is my theory. It is just a theory, but I think it makes some valid points:

      http://arthuriandaily.wordpress.com/201 … gin-birth/

    • #106499
      LeoPol
      Participant

      Scottie

      Initially, the Earth as a planet and all, had a higher hydrogen atmosphere with small amounts of oxygen, nitrogen, carbon. Then there was the dissipation of solar wind hydrogen. Oxygen, nitrogen and carbon remained, and the hydrogen is moved farther – to the giant planets, which gradually adsorbed. Venus has an obvious deficiency of hydrogen, so there is nothing to do water ocean! But on Jupiter’s moon – Europe – more water than all the oceans of the Earth!

    • #106500
      scottie
      Participant

      arthuriandaily

      Your speciality appears to be random ramblings.
      My advice would be to stick to what your good at, not that you have to follow it.
      However if you do then less ignorance of science would be displayed.

      Leopol

      quote :

      Initially, the Earth as a planet and all, had a higher hydrogen atmosphere with small amounts of oxygen, nitrogen, carbon. Then there was the dissipation of solar wind hydrogen. Oxygen, nitrogen and carbon remained, and the hydrogen is moved farther – to the giant planets, which gradually adsorbed. Venus has an obvious deficiency of hydrogen, so there is nothing to do water ocean! But on Jupiter’s moon – Europe – more water than all the oceans of the Earth!

      I don’t necessarily disagree with you, as you seem to be making the same point that the lecture I referred to makes.

      The lecture concludes with this point.

      quote :

      The questions that need to be answered then are:
      1. Where did all the water go that must have been ejected into the atmosphere of Venus?
      2. Where did all the Carbon Dioxide go that must have been ejected into the atmosphere of Earth?
      3. Why does the Earth have so much Oxygen in its atmosphere and Venus has none?

      My point is that questions 2 and 3 that relate to the earth, are not being adequately addressed by evolutionary theorists.

      Accretion theory that you and the lecture clearly are referring cannot answer these questions, therefore the answer must lay elsewhere.

      The view that photosynthesis (mainly from cyanobacteria) was the answer lacks scientific credibility simply because the amount of CO2 that would have been required to generate the oxygen we have in the atmosphere would have prevented life from even getting started. That then raises the question as to how the cyanobacteria even got started?

      There is also another problem with this idea of photosynthesis.
      Recall the increase in concentration of 0.0051% in CO2 since about 1750.
      This is telling us that all the photosynthesis currently occurring today has not been able to absorb just this small percentage of CO2.

      How much vegetation can we imagine would have been required to absorb all the 21% CO2?

      This whole idea is fundamentally flawed.

      All this goes to buttress my argument that an outside agency was involved.
      That is why the genesis narrative (without all the bells and whistles that creationists attach to it) makes sense.

      There are none of these chicken and egg situations we continually find in materialist explanations.

    • #106501
      LeoPol
      Participant

      scottie

      Well water – hydrogen and oxygen, and, two moles of hydrogen per mole of oxygen. With Venus hydrogen dissipated due to the solar wind, so the oxygen contacted with carbon. The result was the CO2 and CO.

      The theory of accretion, I do not like. I believe that all the planets, stars, the so-called "Main Sequence" – were released in the form of fragments from the end sleeves Central galaxy’s hyper-astroid. It’s such a huge Laplace-black-star in the center of galaxy, weight – how many millions of solar masses. From two opposite-facing spindle-shaped elevations on the equator of the object under the influence of centrifugal forces are constantly torn plume material, which is fragmented into pieces of various sizes, with the Coriolis force, give them the time of rotation. Since are formed spiral arms of galaxy.

    • #106502
      LeoPol
      Participant

      scottie
      Oxygen was first associated with the whole hydrogen due to an excess of hydrogen. But after the dissipation of most of the hydrogen started radiolysis of water in the upper atmosphere. Oxygen remained, and hydrogen – dissipated. Later, when the Earth moved in from outer space holders nano-molecular peptide nucleic technology, the situation began to change. Apparently, these first settlers were stored after photosynthesis in the form of oxygen, peroxides, and hydrogen – in the form of hydrocarbons.
      But if by the time of colonization of these intelligent ancestors of bacteria in the atmosphere and hydrosphere have been a lot of oxygen – oxygen store in the form of peroxide was not necessary …

      But if, in the hydrosphere, or anywhere else would be an excess of hydrocarbons … Wow! ! It’s on Titan! That’s where the bacteria stockpile peroxide instead of carbohydrates! Yyess, it also goes in my sci-fi story! 😉

    • #106504
      LeoPol
      Participant

      Yes, the question, where did the carbon in the Earth’s atmosphere? And it got in touch with calcium and oxygen in carbonates. Yes, even in deposits shale, coal and oil.

    • #106509
      vinayaksabnis
      Participant

      Try to look for Miller-Urey experiment and more alike experiments which concluded origin of life .

    • #106514
      scottie
      Participant

      Leopol
      I know we are going off subject a bit but it does have some relevance.

      I agree about accretion theory. It creates more questions than it provides answers, but it is a poplar theory and that is why I cited it.

      However the Laplace Black star model also has it’s problems.

      By defination a Laplace black star has an escape velocity that is greater than light speed.
      Any matter leaving it will be moving at less than light speed. Therefore it will return to the star as gravitation pulls it back.
      It therefore cannot escape to form planets etc unless it travels at a greater velocity than the black star’s escape velocity.
      I am not aware of any accretion mass that has been known to travel at above light speed.

      However this is all really quite academic, because whether the atmosphere contained either CO2 or O2 it would not matter. Either way metabolic pathways could not get started.
      The theory of photosynthesis is fundamentally flawed.

      As I have stated before there is no scientific reason to conclude that the current atmospheric breakdown was any different to when life first started..

      btw have you been in touch with James Cameron yet 🙂

    • #106518
      arthuriandaily
      Participant

      [quote="scottie"]arthuriandaily

      Your speciality appears to be random ramblings.
      My advice would be to stick to what your good at, not that you have to follow it.
      However if you do then less ignorance of science would be displayed.

      Leopol

      Interesting, though the relevance seems to be as elusive as the scientific evidence.

      Is there any specificity, or is the randomness of generality your specialty?

      Arthurian

    • #106537
      LeoPol
      Participant

      arthuriandaily

      I am a molecular biologist, in general, like biology, astrophysics, and much more! It’s a hobby, but I can find the necessary literature and now I can recognize manipulation. Here, for example, "black holes" of general relativity and the "Black Star Laplace" – it was interesting to me. I realized that the so-called "Black holes "of general relativity – is a clever manipulation, which deliberately ignored the kinetic energy! It turns out that the approach to the singularity of the density requires an infinite energy! And because there is nowhere to take it, then this state is not achievable. So there is only "Black Star Laplace".

    • #106572
      scottie
      Participant

      vinayaksabnis

      quote :

      Try to look for Miller-Urey experiment and more alike experiments which concluded origin of life .

      Do I take it to mean that you consider the Miller-Urey experiments and other like ones to have answered the question as to how life originated, or did you mean that these experiments demonstrated the opposite?

      Could you clarify please.

    • #106614
      scottie
      Participant

      vinayaksabnis

      Raises the experiment of Stanley Miller back in the 1950’s.

      I am not sure what his view actually is regarding the results, I await his clarification.
      However his experiment and indeed succeeding ones did show one clearly noticeable feature.

      Robert Shapiro had a comment on this in the edge event I have referred to before.
      He recounts a meeting he had with Stanley Miller.

      quote :

      At one point I went and spoke to the now, unfortunately, late Stanley Miller, and asked him about the circumstances of his famous Miller-Urey experiment — the one with the electric lightning and amino acids were formed — and he handed me a biographical piece he himself had written to something called the Transactions of the Copernican Society or something like that, and he described how in building his apparatus he was concerned with questions of safety, because if you take a flask and you mix it with methane and hydrogen and ammonia, the most likely result is BOOM, with flying glass in all directions, which is definitely not publishable.
      With regard to safety, he built a certain apparatus, let it run for a number of days, and at the end of the days he looked at what he’d found and he found the class of chemicals called hydrocarbon — the stuff that makes up the lakes on Titan but no amino acids whatsoever. And he looked at this and he said, this isn’t interesting. And he threw it out. He redesigned the equipment: he said, I was over-cautious. This is not likely to explode. He interchanged the spark and the condenser and he re-ran the experiment, and this time he got amino acids and not hydrocarbons, and he said, Ah ha! And he published.
      Thus we have the famous Miller-Urey experiment showing the inevitability of
      amino acids on the primitive Earth.

      The above is on a video clip here. (scroll about half way down to locate it)
      http://www.edge.org/documents/life/life_index.html
      The rest of his comment is transcribed below and is available in pdf form on the same site from page 90.

      quote :

      And of course the apparatus itself has no resemblance whatsoever to the primitive Earth. One of the popular magazines said that if his apparatus had been left on for a million years, something like the first living creature might have crawled out of it.
      And I say, if he’d left his apparatus on for a million years, he would have run up one hell of an electric bill. But nothing further would have happened because the spark was in the atmosphere and he’d used up all of the chemicals with carbon in the atmosphere, and the amino acids, which aren’t volatile — they don’t fly, so to speak — were safely ensconced in the water solution, and the water solution was a collection of non-volatile compounds, well, and the volatile compounds ended up in — so when an experiment goes wrong in organic chemistry you get a black gook and you reach for the potassium bichromate and sulfuric acid — mixed together it’s a called cleaning solution — that cleans out about 90 percent of the failed organic experiments that are ever run.
      You use that and you can get rid of the tars in about 80 to 90 percent of his
      carbon, this stuff that had unfortunately flown again and again until it got zapped and ended up as tars on the wall of his flask.
      Well, this was the best prebiotic experiment ever run, because at least he started with components that hypothetically could have been on the early Earth.
      Since then, so-called prebiotic chemistry, which is of course falsely named,
      because we have no reason to believe that what they’re doing would ever lead to life — I just call it ‘investigator influenced abiotic organic chemistry’ — has fallen into the same trap. ……

      ….The point is, you would take whatever mess prebiotic chemistry gives you and you would concentrate that mess so it’s relevant to RNA or the origin of life — it’s all in the eye of the beholder. And almost all of prebiotic chemistry is like this; they take chemicals of their own selection.

      The point that Shapiro is making, and he is an evolutionary scientist, is this.
      Investigators design their own atmosphere that has nothing to do with the reality of prebiotic conditions.
      They prepare their designs to try to achieve the result they are seeking. That is the start and end of it.

      With these atmospheres that are cooked up in a lab, has any serious thought been given as to how that particular atmosphere could have naturally developed?
      Of course not, because no theory can account for it.

      Their atmospheres are specifically designed to produce the result they wish.

      In the genesis narrative that is precisely what is stated. The atmosphere was specifically designed to accommodate the life that was to come.

      Of course a materialist view says you can’t have an outside agency designing because science can only deal with natural processes.
      The irony that seems to escape this type of thinking is that the very processes they are denying, they actually use to prove – what?
      That the prebiotic atmosphere can only come about by design. 🙂

    • #106616
      JackBean
      Participant

      You’re using stupid logic. Just because we can create something, doesn’t mean, it must be created by someone.

    • #106617
      JackBean
      Participant
      quote scottie:

      What does chemistry tell us?

      We have rocks, made up of granite. Granite consists of different amounts of Quartz (SiO2) Feldspar of which there are three kinds (KAlSi2O2, CaAlSi2O2, and NaAl2Si2O2), and Mica (every Mica molecule contains 12 Oxygen atoms (O2).
      Limestone and Marble contain copious amounts of oxygen atoms as well.
      So there is plenty of oxygen atoms in rocks.

      Water contains oxygen (H2O)

      Now stellar evolution tells us that accretion was the process that formed the Galaxies Stars and planets. The process consists of the collision of microscopic dust (the elements) and then sticking together. Let’s assume this is correct.

      So the hypothesis is that all these, rich in Oxygen compounds, formed the rocks and water but without a remainder O2 for the atmosphere.
      What is the physics or chemistry that can confirm this? There is none.

      I though you are an engineer, but obviously not in chemistry, right? So you have no education in related fields whatsoever, but you will complain all the time.
      Nevermind, the point is, that oxygen is quite reactive and thus it reacts with the other elements and forms other compounds. If you knew anything about chemistry, you would know, that getting oxygen from SiO2 is really hard task.
      Furthermore, there are other planets where there is oxygen in some compounds, but it is not in the atmosphere as O2 and this is no speculation. So why should we assume that the early Earth was different?

      And how did the oxygen arise? Well, from the organisms, obviously.

    • #106620
      scottie
      Participant

      Jackbean.

      Where did I say that oxygen formed from Quartz or Feldspar?
      It didn’t and that is my argument. Please read what I am writing.

      The oxygen must have been around in the compounds that formed the rocks according to the theory of accretion.
      For it not to be around after the rocks formed must mean that all the oxygen was used up with no remainder, for any atmosphere. That was what I said.

      Now is that realistic?

      Because that is the theory of a pre-biotic atmosphere.

      Therefore the question is where did the oxygen come from?

      You say

      quote :

      Well, from the organisms, obviously.

      So a simple question now
      What organisms are you referring to.

      Now think before you respond, as I have no desire to see you digging a bigger hole for yourself.

    • #106629
      JackBean
      Participant

      You said:

      quote scottie:

      What is the physics or chemistry that can confirm this? There is none.

      And I’m saying, that it’s basic inroganic chemistry, which tells us that.

      So, where do you think does the oxygen come from if not from the rocks?

    • #106633
      scottie
      Participant

      Jackbean

      I am finding it very difficult to understand why you appear to not appreciate the obvious. Maybe it is a language problem

      So may I try again

      In my post that you refer to I stated

      quote :

      Now stellar evolution tells us that accretion was the process that formed the Galaxies Stars and planets. The process consists of the collision of microscopic dust (the elements) and then sticking together. Let’s assume this is correct.

      So the hypothesis is that all these, rich in Oxygen compounds, formed the rocks and water but without a remainder O2 for the atmosphere.
      What is the physics or chemistry that can confirm this? There is none.
      So why is it so emphatically stated that the early earth had no oxygen?

      If the accretion process from material that was rich in O2 formed the rocks and water all of which are themselves rich in oxygen, why is it claimed that the atmosphere lacked oxygen?
      What is the physics or chemistry that justifies this claim?
      I said there is none.

      So for my education as I am obviously unacquainted with chemistry, can you explain a physical or chemical process controlling accretion that does, on the one hand make use of the oxygen rich material to produce the rocks and water, but on the other not leave any free O2.

      You need to explain this if you are to state that there was no O2 in the prebiotic atmosphere, and even more bizarrely that “organisms” produced the O2.

      I am saying quite clearly, with my limited understanding of chemistry, that if this process of accretion which so clearly assumes a material mass rich in O2 is correct, then this very same process would have had some remaining O2 as a constituent part of the atmosphere.

      I hope that is clear enough

    • #106634
      JackBean
      Participant

      the thing is, that the materials such as sillicates are so stable, that they do not release oxygen, similarly other elements react quickly with oxygen to form oxycompounds. These are mostly stable, definitely more than free oxygen.

      By the organisms, I mean of course the evolved bacteria. There are plenty of articles, which track the level of oxygen in the past. I’m sure, you will find some, since you’re so great with the resources 😉

    • #106639
      LeoPol
      Participant

      scottie
      Oxygen could get into the atmosphere once, 4 billion years ago when crossing the plume from the central galactic hyper-astroid Laplace in a place where centrifugal force is born spiral arm of the Galaxy. Nitrogen, by the way, too, like gold, and many other things! http://www.bbc.co.uk/news/science-environment-14827624

      JackBean
      http://www.biolib.cz/en/taxonimage/id81 … nid=125696 Wow! mushrooms … http://spacenoology.agro.name/?page_id=4349 I wonder what they were then, a billion years ago?
      (Off the top, sorry!) my daughter (13 years) now decides to do after school to learn. Here, in Kiev – is expensive, the U.S. – far and definitely not, in England – too expensive, and that in Prague? Maybe it’s time to start teaching her to Czech? 8)

    • #106640
      scottie
      Participant

      Jackbean

      quote :

      There are plenty of articles, which track the level of oxygen in the past. I’m sure, you will find some, since you’re so great with the resources

      In other words you don’t know. 🙂
      Now you are getting really careless in asking me to find your resource articles.
      Do you really wish to be even more embarrassed? 🙂

      However you have had a stab at what you refer to as "evolved bacteria" as the organisms that produced the oxygen.

      So may I remind you what the chemistry involved is. The process your “evolved bacteria” would need is photosynthesis. The popular hypothesis that this “evolved bacteria” is cyanobacteria..

      I explained all this to Leopol a little while ago,
      by scottie » Thu Sep 29, 2011 1:05 pm
      about14351-228.html
      However lets try again.

      Our current atmosphere contains about 21% Oxygen.
      Now in the process of photosynthesis it takes one CO2 molecule (Carbon Dioxide) to produce one carbon atom and one O2 (oxygen gas) molecule.

      So if there is 21% oxygen in the atmosphere now, then therefore must have been 21% Carbon dioxide in the early earth atmosphere.

      Therefore what effect do you think an atmosphere containing 21% CO2 would have on life.

      May I suggest fully absorb the reference to Venus’s CO2 enriched atmosphere and then consider how your “evolved bacteria” could have survived let alone got started.

      Please stop looking for “fairies at the bottom of your garden” they are not there. 🙂

    • #106641
      LeoPol
      Participant

      scottie
      I think those ancient reasonable membranoids in Venus would create a special way of photosynthesis. They would have done such a super-heat-resistant catalytic process in which energy of absorbed photon was spent on a separation of CO2 – C + O2. Moreover, both components would be stocked in separate granules and vacuoles! And this technological structure would require the presence of special membrane rhizoids, which would look in the substrate compounds containing hydrogen – for exothermic synthesis of water! Energy would be allocated, by the way, can also be used for CO2 – C + O2!

    • #106643
      scottie
      Participant

      Leopol

      The BBC love this type of headline grabber and treats reports such as this as fact.

      The Nature article concludes with this acknowledgement by the authors.

      quote :

      We speculate that both observations can be explained if late meteorite bombardment triggered the onset of the current style of mantle convection.

      Willbold, M., T. Elliott, et al. (2011). "The tungsten isotopic composition of the Earth/’s mantle before the terminal bombardment." Nature 477(7363): 195-198.

      Btw these researchers are basing their ideas on Accretion Theory that you don’t agree with

      "membranoids" —- Not my type of music 🙂

    • #106651
      LeoPol
      Participant

      scottie
      Well, actually, I’m not against accretion. Central hyper-astroid initially formed from the stars – the white giants that – the main population of elliptical galaxies. Such stars – pure hydrogen-helium white giants, as these galaxies formed by accretion (in my opinion). And later in the centers of these galaxies after falling stars on the growing star-monster appears hyper-astroid and stretched in the equatorial plane in a giant rotating spindle, which is detached from any planetoids and stars type "Main sequence". :mrgreen:

      Well, me, my "music" is quite suitable. Because this is my way to solve that problem, now called the crisis of the genre in molecular biology. Now the question is, what can explore methodological complex nano-phenomena in the cell membrane to describe it, "consciousness" of the cell – the "Active membrane model of the World on … Spirit? Continuum?" – Oh, what’s the difference? 8)

    • #106652
      LeoPol
      Participant

      scottie
      So. Posted by Mr. Dawkins, another message. In my opinion, he does not read them.

      http://richarddawkins.net/articles/6433 … ins?page=2

    • #106665
      scottie
      Participant

      Jackbean

      May I put this to you.

      You have a sincere belief in the evolutionary hypothesis and I understand that and respect it.

      However unless you can establish those views have a scientific basis, then it is only a belief system like any other.

      In order to get life started, for evolution to get going you have to believe that the early atmosphere lacked oxygen.

      So an atmosphere lacking oxygen had to be designed to test out the view.

      That design, whatever the combination of gases,is confronted with major problems.
      1) Many experiments involving an oxygen free atmosphere have produced amino acids, the basic molecules in living organisms. However the energy that created these molecules also destroys them. That is why Miller and others had to get them out of the system once created. What natural process could have done that? (The problem has not even been addresses as far as I know)
      2) All the experiments produce both left handed and right handed amino acids in more or less equal quantities. The life processes use only the left handed ones. Right handed ones are toxic. What natural processes are able to differentiate between them?
      3) If life did evolve in, say an ammonia/methane environment, that organism had to evolve into one that breathes oxygen. How did that happen? Again there is no plausible explanation that has been offered.
      4) How did the oxygen free atmosphere become an oxygen rich atmosphere? There have been a few attempted explanations, here is a statement on the subject of photosynthesis that you have referred to.

      quote :

      Perhaps most importantly, how did the oxygen produced by photosynthesis get incorporated into the continents? This could not have occurred by direct oxidative weathering because that is contradicted by the persistence of detrital uraninite and pyrite in Archean sediments.

      Science, Kasting, Vol. 293, 3 August 2001, “The Rise of Atmospheric Oxygen”, page 819
      5) How did the genetic code evolve? Koonan for example refers to this as an intractable problem

      Here we have a clearly designed atmosphere that has proved not to be correct simply because for the past 60 years or so all attempts to surmount these problems I have mentioned above have failed.
      Clearly no natural explanation has proved plausible. That is not in doubt.

      When I suggested that the only plausible answer was that the atmosphere was clearly designed correctly with it’s O2 content right at the start of life that is also designed all those problems go away.

      Yet you responded this way

      quote :

      You’re using stupid logic. Just because we can create something, doesn’t mean, it must be created by someone.

      Now forget that I am using stupid logic as you put it, would you like to rephrase the second half of your statement because it makes no sense to me.
      I simply do not know what you mean.

    • #106672
      JackBean
      Participant

      You know, I’m tired of arguing with you. That’s problem of all of you, anti-evolutionists, you rather beat your opponents by writing lots of long posts, which may sound nice (how else would you get followers, right?) than by true arguments.
      You are trying to look clever, but the least mistake you’re doing is mixing origin of life and evolution. You should make it clear for yourself first, what are you talking about.

      Regarding the oxygen, I know there are some articles, I have read some, but I’m not much willing to spend time searching them now (yeah, I’m sorry, but my memory is not that good to remember every article I’ve read years ago). But you’re obviously using only these facts, which are usufull for you.

      The fact, that we can create something is not proof that it must be created by someone and it cannot "evolve".

    • #106674
      scottie
      Participant

      In other words you only believe what you think you know, but can’t be bothered to actually find out if it is correct.

      That’s fair enough, belief based on emotion is a very difficult thing to combat, why should you want to change your comfort zone for the real world. 🙂

      Hope this post is short enough.

    • #106675
      oldman
      Participant

      Jackbean (and other participants in this thread).
      It`s a mystery to me why you all encourage this pseudoscientific monologue to go on and on and on. Your arguments are only adding fuel to the fire. And you should know it. It`s like debating holocaust- deniers. You can newer answer all their shoe box questions and their citing of known and unknown historians. So you don`t do it. You know their motives and you know their tactics and you don`t invite them into an arena of honest and open thinking. It`s not about censorship, but about decency, really. On a biology forum I would not expect creationists given free space to prove their point that science can`t agree on the basics of life on earth. This thread serves to verify the“fight” inside the science community, which we know is false, but nevertheless demonstrated here. Science is about placing evidence before conclusion, not the other way around, like creationists do. Yes, I took this forum to be a science forum. But this never ending stream of modern day creationism proved me wrong. It`s a pity.

    • #106679
      scottie
      Participant

      Nice bit of rhetoric, but as you say,

      quote :

      I took this forum to be a science forum.

      So where is your science.

      See another short post 🙂

    • #106683
      LeoPol
      Participant

      scottie
      Hmmm. Well, actually, personally, I do study at first, and then concluding, moreover, my idea – not creationism. I criticize creationism and criticize distorted evolutionism that creationism is a giveaway. So this is Mr. Oldman’s not about me!

    • #106692
      scottie
      Participant

      Leopol

      quote :

      So this is Mr. Oldman’s not about me!

      Absolutely correct.
      I thoroughly enjoy your posts

      I am sorry you thought I was referring to yourself. I was simply responding to the rather bizzare outburst from oldman.

      To my knowledge since he registered in June he has contributed just twice to this forum.
      On both occasions he has directed his rather tribal fire at me personally. No science, just vitriol.
      I suppose he needs to regularly vent his spleen as his frustration builds. 🙂
      His statement

      quote :

      On a biology forum I would not expect creationists given free space to prove their point that science can`t agree on the basics of life on earth.

      Well it speaks for itself. " Dissent will not be tolerated" mein Furheur 🙂

      I will consider myself quite fortunate if I don’t get anymore blasts of this nature.

    • #106693
      LeoPol
      Participant

      scottie
      In the Soviet Union was such a terrible time – Stalinism, and then was biology – Lysenkoism. Then the right was declared dogma Trofim Denisovich Lysenko, certain, and everything else – was considered the machinations of world imperialism. Then anyone who did not agree with the dogmas of Lysenko either shot or sent to concentration camps for life. Well, now we have some new trends on a global scale! .. The scientific controversy – administrative arguments. All learn to get version of evolutionary theory "from simple replicators to evolutionary crown of creation" and to ban argue with that! And anyone who does not agree – to declare "creationists" and "excommunicated", that is only true of the "admin-science"! And the fact that the opponents of the theory of creationism and does not smell – it does not matter. It remains to arrange the world "cultural revolution" with the Red Guards of Mao on the script – and … Hello, Sunset Civilization! 😉

    • #106720
      scottie
      Participant

      Leopol

      Sorry for the delay.
      I didn’t know about Lysenkoism., so I had to do a little research.
      I get your point though.

      If only serious minded people would put their religious beliefs aside when discussing science matters there would be a lot less angst around. When I use the term religious beliefs, I include the materialists who after all claim to be atheists.

      In the past the Churches ruled the roost and demanded allegiance to their dogmas.
      That has now been taken over by the material atheists who demand the same allegiance, with the creationists and Id people trying to reclaim their lost ground.
      Darwinism has now become the new dogma and any other view is crackpot and deserves only ridicule.
      Although that is now changing again.

      Funny old world 🙂

    • #106722
      JackBean
      Participant

      you’re wrong again. Darwinism is overcome for some time. Since that time there has been several other theories so you’re actually fighting a dead man (and this is meant imaginary, not Darwin)

    • #106739
      scottie
      Participant

      One of the great difficulties I have had, was in trying to get any of my detractors to explain what their understanding of evolutionary theory was.
      I finally decided to explain my understanding and then at last canalon posted his agreement with it, albeit with some additions.
      I didn’t notice you offering any other view, so your latest statement lacks any weight.

      I thought we had gone past this obfuscation.
      by scottie » Thu Aug 25, 2011 12:51 pm
      about14351-180.html

      You know very well what I mean by Darwinism so please stop trying to play word games.

    • #106775
      LeoPol
      Participant

      Darwin’s theory – "On the origin of species by natural selection." Vulgar evolutionism – a hybrid between Darwin’s theory and the idea of ​​the origin and evolution of life from primary primitive replicators to "crown of the evolutionary creation" – Homo Sapiens-sapiens-sa-…xn…-ns… Meanwhile, Darwin’s theory does not contradict the theory of devolution! Quite the contrary – a perfect match. But only at those stages when there is no intellectual activity and create and develop technology.

      Here’s an interesting example of devolution – the distribution of gene technology between the new species, outgoing from the initial species of the universal type.
      "In all vertebrates, some insects and mollusks in the blood protein is present ferric iron, but because their blood has a red color. Blood clam brachiopods contains hemerythrin – it contains iron to five times more than the hemoglobin. Oxygenated blood hemerythrin gives a purple hue, and gave oxygen to tissues, such blood turns pink. In polychaetes – the other iron-containing protein – hlorokruorin. The basis of it is not ferric iron, ferrous and which gives the blood and tissue fluid green. In ascidian blood is colorless, it is based – gemovanady containing vanadium ions. In octopus, spiders, scorpions, crabs, respiratory pigment of the blood is hemocyanin, in which iron is present instead of copper (Cu2 +). Combines with oxygen of air is blue hemocyanin, and by giving oxygen to tissues – a few discolored. As a result, the arteries flowing dark-blue blood and the veins blue. However, some shellfish oxygen transport of substances close to the hemoglobin, and other similar proteins contain manganese." http://otvet.mail.ru/question/16010365/
      That’s because, as interesting! Some evolutionists, created a series of painful anthropocentrism taboo. For example, some evolutionists reject even the thought of which created a strong di-polivergence of species of amphibians-Turbellarians in the Cambrian paleo-civilization, who had blood all at once these blood pigments! 😉

    • #106830
      scottie
      Participant

      Lets get back to basics.

      The cell is the basic unit of life.
      No one has disputed that simple fact.

      All the internal molecular systems inside the cell are, in themselves, inert.
      Again no one has disputed that.

      The simplest form of life is a single cell prokaryote,..
      Again no one disputes that.

      E coli is a single cell prokaryote and is classed as a species of bacteria.
      Again I don’t expect any one to dispute this either.

      It is obvious therefore that the basic unit of life is also the basic unit of a species

      Therefore the origin of life and the origin of species are one and the same thing.

      Proteins are probably the most important class of biochemical molecules, although of course lipids and carbohydrates are also essential for life. Proteins are the basis for the major structural components of animal and human tissue.
      http://www.elmhurst.edu/~chm/vchembook/565proteins.html

      A Ribosome is a molecule consisting of two subunits that read the genetic sequence and makes Proteins.
      A prokaryotic ribosome is made up of three kinds of ribosomal RNA (rRNA) and about 50 types of protein.
      The eukaryotic ribosome, however, consists of five types of rRNA and around 80 types of protein.
      http://www.wisegeek.com/topics/eukaryotic-ribosome.htm

      The cell membrane or plasma membrane is a biological membrane that separates the interior of all cells from the outside environment. The cell membrane is selectively permeable to ions and organic molecules and controls the movement of substances in and out of cells. It basically protects the cell from outside forces.
      Integral membrane proteins penetrate or are embedded in the phospholipid bilayer.
      Without the membrane to protect it the cell would disintegrate.
      http://en.wikipedia.org/wiki/Cell_membrane

      This is all pretty basic biology that even an engineer can comprehend. 🙂

      Now here is the dilemma for any origin of life biologist.

      The Ribosome manufactures the protein, but it itself is made up of at least 50 proteins.
      Ribosome cannot exist unless there are Proteins around.
      Proteins cannot exist unless there are Ribosomes around.

      The cell membrane cannot exist unless there are proteins about.
      Ribosomes and Proteins cannot exist unless the is a membrane around.

      This is one of the many conundrums the cell exhibits.

      Neo Darwinian theory centers on Natural Selection as being the process that drives the evolution of living organisms.

      It is obvious the proteins along with the other cell components are inert and therefore cannot be subject to any process of natural selection. The only laws applicable to any inert molecules are the natural laws governing physics and chemistry.

      As I have reported before, there are no plausible natural biochemical pathways that lead to the formation of a cell. This is coming from the most august of scientific Institutions.

      There is also the matter of the origin of the genetic code which again is being shown to be, not a natural process.

      Therefore the only plausible pathway to cell formation is an artificial process. This is a process that is regularly demonstrated in Genetic Labs around the world.

      However the difficulty goes beyond that.
      Even if we assume that somehow the cell can or was constructed there is still the problem of how the cell can come alive.
      This can be said for two reasons.

      1) Viruses are very complicated molecules made up of proteins, nucleic acids, lipids, carbohydrates etc. Yet they are not considered alive because, without cells they are unable to multiply. There are other reasons as well. Now if these very complicated molecules made from basically the same ingredients as cells, do not constitute life, it shows that that life is something more than the bringing together of these very complicated molecules.
      2) We already know that life comes only from another life. This is an established biological fact.

      These conclusions are based on science, logc and evidence.

      What prevents any biologist from acknowledging these conclusions other than a philosophical bias?

    • #106834
      aptitude
      Participant
      quote scottie:

      The Ribosome manufactures the protein, but it itself is made up of at least 50 proteins.
      Ribosome cannot exist unless there are Proteins around.
      Proteins cannot exist unless there are Ribosomes around.

      The cell membrane cannot exist unless there are proteins about.
      Ribosomes and Proteins cannot exist unless the is a membrane around.

      This is one of the many conundrums the cell exhibits.

      I think you just disproved the existence of the cell. 😆

    • #106838
      LeoPol
      Participant

      Scottie, hrotects the cell cell envelope. Membrane does not protect, but a universal substrate for placement and activation of polypeptide production lines and signaling. This is in terms of technology. But the logic of the theory of "Engineering design and the Macrodevolution" of the membrane – a direct descendant of those smart membrane beings who once created a nucleic polypeptide molecular nano-technology.

    • #106887
      scottie
      Participant

      aptitude

      quote :

      I think you just disproved the existence of the cell.

      Correction — What I have shown is that there is no natural explanation to the origin of the cell.

      Maybe you need to do some more work in your understanding of language.
      Certainly your understanding of biology is at best, a "work in progress".

      I understand your need to avoid the issue so all you can be left with, is your rather particular form humour.

      However please carry on, at least you are providing some entertainment, if nothing else. 🙂

    • #106889
      scottie
      Participant

      Let get some more basics up front.

      Two among the most prominent evolutionary proponents of evolutionary theory today are Richard Dawkins and Freeman Dyson.

      Here are some extracts from an email exchange between these two scientists.

      Freeman Dyson view.

      quote :

      “By Darwinian evolution he [Woese] means evolution as Darwin
      understood it, based on the competition for survival of noninterbreeding species."

      “With rare exceptions, Darwinian evolution requires established
      species to become extinct so that new species can replace them.

      Dawkins response by email is here.

      quote :

      “These two quotations from Dyson constitute a classic schoolboy howler, a catastrophic misunderstanding of Darwinian evolution. Darwinian evolution, both as Darwin understood it, and as we understand it today in rather different language, is not based on the competition for survival of species. It is based on competition for survival within species. Darwin would have said competition between individuals within every species. I would say competition between genes within gene pools. The difference between those two ways of putting it is small compared with Dyson’s howler (shared by most laymen: it is the howler that I wrote The Selfish Gene partly to dispel, and I thought I had pretty much succeeded, but Dyson obviously hasn’t read it!) that natural selection is about the differential survival or extinction of species.’’’”

      DYSON:

      quote :

      Good. Yes, I have two responses.
      First, what I wrote is not a howler and Dawkins is wrong. And I have read his book. Species once established evolve very little, and the big steps in evolution mostly occur at speciation events when new species appear with new adaptations. The reason for this is that the rate of evolution of a population is roughly proportional to the inverse square root of the population size. So big steps are most likely when populations are small, giving rise to the “punctuated equilibrium” that is seen in the fossil record. The competition is between the new species with a small population adapting fast to new conditions and the old species with a big population adapting slowly.

      You will find this exchange from the recent discussion “Life what a concept” at the Edge Special Event.
      http://www.edge.org/documents/life/life_index.html
      You will need to scroll down almost to the bottom of the page.

      So whose is right?

      Is it Dyson, whose understanding of Darwinian evolution is based on Competition between non interbreeding species
      Or is it Dawkins view based on competition for survival within species.

      What does this say about any factual basis for the theory?

      Is it any wonder that no one on this forum was confident enough to explain their view. I eventually had to spell out one view to even elicit a response.

      It says nothing other than merely reaffirming my statement that this is all about philosophy.

    • #106896
      aptitude
      Participant
      quote scottie:

      aptitude

      quote :

      I think you just disproved the existence of the cell.

      Correction — What I have shown is that there is no natural explanation to the origin of the cell.

      Maybe you need to do some more work in your understanding of language.
      Certainly your understanding of biology is at best, a “work in progress”.

      I understand your need to avoid the issue so all you can be left with, is your rather particular form humour.

      However please carry on, at least you are providing some entertainment, if nothing else. 🙂

      Very funny, scottie.

      You are arguing that the cell cannot function since the ribosome is part protein, and the ribosome is responsible for peptide synthesis; therefore, according to you, the protein cannot be part of the ribosome. Yet, obviously this is not true. Because the ribosome seems to be ubiquitous in almost all organisms, the ribosome must have originated very early in the history of life. Ribosome evolution began with a complex of nucleic acids that probably had another function early on, but acquired the function of protein synthesis. Only later were proteins incorporated into the ribosome.

      quote scottie:

      Maybe you need to do some more work in your understanding of language.
      Certainly your understanding of biology is at best, a “work in progress”.

      I would have been a creationist if my biology knowledge was as limited as you claim. All I am going to say is that your knowledge of evolution would have been a lot more complete had you consulted a biology textbook sometime in the past. If you want to know more about the origin of cells, please consult external sources on abiogenesis before posting a reply. The most important experiments are Fox’s experiments with protobionts, and Wachtershauser’s hypothesis. The Wikipedia article for abiogenesis should be a great help.

      Please take the time to understand the responses that others are posting before you attempt to attack the response and try to "further" your argument.

      Cheers,

      aptitude

    • #106904
      Gavin
      Participant

      I’m not willing to slog through 23 pages to try to figure out what’s going on here. Reading through a few random pages, though, I can’t see what most of this has to do with the origin of life. All I can discern is the standard, tiresome creationist/rationalist crap sprinkled with a dash of delusion. Is there a point to any of this, or do all of you just have too much time to waste? May I suggest that individual discussions have their own threads? This one just seems to be a dump for anything anyone wants to say.

      Scottie: can you state your position in 25 words or less (concerning the origin of life)? If you have something else in particular you would like to discuss, could you please start a new thread?

      Leopol: What’s the weather like on your planet? Photos would be welcome.

      The origin of life is, of course, a very interesting topic, one that has entertained me for a very long time. I know I will die without ever knowing how it occurred, but that has never detracted from the enjoyment of my ignorance. Ignorance is what science feeds on. Anyone who says "I know" or dares to use the p word (proof) is automatically disqualified.

    • #106937
      LeoPol
      Participant

      Gavin
      In the northern hemisphere – autumn in the south – spring. In the tropics, warm, at the extremes – cold.
      Very sorry, uh … but may I ask your permission at least to make assumptions?

      🙄

    • #106938
      JackBean
      Participant
      quote scottie:

      1) Viruses are very complicated molecules made up of proteins, nucleic acids, lipids, carbohydrates etc. Yet they are not considered alive because, without cells they are unable to multiply. There are other reasons as well. Now if these very complicated molecules made from basically the same ingredients as cells, do not constitute life, it shows that that life is something more than the bringing together of these very complicated molecules.

      Wrong again, viruses are much simplier than the simplest cell. Usually they contain only the nucleic acid, sometime with protein package. However, if they contain lipid membrane, it originates from the host cell, from which the virus takes it during leaving it.

      quote scottie:

      These conclusions are based on science, logc and evidence.

      So, now is logic good enough for you?

    • #106950
      scottie
      Participant

      Jackbean

      quote :

      viruses are much simplier than the simplest cell

      That is correct.
      Where have I said anything different.
      I merely said that they are very complicated molecules, which of course they are.

      What on earth are you arguing against.

      It would greatly help your obvious frustration if you actually read what I write, before replying with a shot through your own foot.

    • #106951
      JackBean
      Participant

      maybe if you read more than you cited, you would know, why I have replied to you.

    • #106952
      scottie
      Participant

      aptitude

      quote :

      Because the ribosome seems to be ubiquitous in almost all organisms, the ribosome must have originated very early in the history of life. Ribosome evolution began with a complex of nucleic acids that probably had another function early on, but acquired the function of protein synthesis. Only later were proteins incorporated into the ribosome.

      Your statement above is what you believe.
      What evidence can you call upon to substantiate this.
      The simple answer is, you are not able to. You can only hypothesise.
      Therefore it is only your belief. And if that is what you wish to believe, then believe it.
      But don’t parade it as scientific fact.

      Look even accomplished biologists like Craig Venter , George Church and others including NASA itself openly acknowledge that there are no plausible pathways to these complex biochemical molecules.
      Have you not bothered to read the papers and articles from prominent members of the Evolutionary establishment that I have referred to.

      Or are you suggesting you know more than them.
      Please, please don’t say Yes. 🙂

    • #106955
      scottie
      Participant

      aptitude

      What I am trying to get over is really quite simple, both in terms of logic and biology.

      Now please read carefully.

      The Ribosome is an essential part of every cell. It is regarded as one of the most complicated molecules in the cell.

      1) It is made up of proteins .
      2) It also manufactures the proteins in the cell
      3) In other words it manufactures the very proteins it is made from.

      How can that be?

      Well the only way this can come about is for a protein to be designed and manufactured .
      The process then repeated some 50 times or so.
      A translation system must then be designed and built.

      A Ribosome can then be constructed with these molecules.
      Then there must be some method of inserting the translation system that can read the coded sequence of amino acids.

      The Ribosome can then be placed into the cell so that it can (along with all the other systems in the cell) commence the manufacturing all the proteins the cell makes.

      In other words some outside agency must be involved in the process.
      No natural laws have the capacity to do this because natural laws do not function in this manner.
      This is a process that some biologists are beginning to attempt to do.

      Can you understand why I say that there is no natural process that can overcome this conundrum.

      It requires an outside agency.

    • #106959
      JackBean
      Participant

      As I told you already dozen times, the crucial part of the ribosome are the rRNAs, the proteins are just added cosmetics. But you refuses to accept that. You think that if something is nowadays composed from proteins, it had to be composed of proteins billions of years ago.

      I’m just curious. This "outside agency" is composed of proteins as well or is it of something else?

    • #106968
      Crucible
      Participant
      quote JackBean:

      As I told you already dozen times, the crucial part of the ribosome are the rRNAs, the proteins are just added cosmetics. But you refuses to accept that. You think that if something is nowadays composed from proteins, it had to be composed of proteins billions of years ago.

      I’m just curious. This “outside agency” is composed of proteins as well or is it of something else?

      That’s an interesting way of handling the "unnatural" influence question.

    • #107004
      scottie
      Participant

      Jackbean

      quote :

      As I told you already dozen times, the crucial part of the ribosome are the rRNAs, the proteins are just added cosmetics.

      Ribosomes are made from approx 40% proteins and 60% nucleic acids (rRNA )

      So, proteins are just added cosmetics.
      Is this supposed to be a serious statement?

      Let me take you to a basic biology refresher.

      The Ribosome is the translation system for the manufacturing of proteins.
      This process starts with Transcription.
      This is the first step in decoding a cell’s genetic information. During transcription, Enzymes called RNA polymerases build RNA molecules that are complementary to a portion of one strand of the DNA double helix.
      What is an enzyme?
      Guess what? It is a protein.

      So our basic refresher tell us that a Protein is required at the start of a process to make (guess what?) a Protein.
      http://www.nature.com/scitable/topicpag … n-14120660

      Now let’s look at your rRNA.
      How does the rRNA come about.

      One of the non ribosomal proteins the nucleolin, is considered to play a key role in the regulation of rRNA transcription, perisomal synthesis, ribosomal assembly and maturation.
      http://books.google.com/books?id=P_ajeM … &q&f=false
      page 161.

      So which came first Protein or rRNA?

      Biology is clearly not a strong point with you.

      Has it not dawned on you yet, the point is not whether proteins are the crucial part or not.

      The point is that Ribosomes, made from proteins, actually make the proteins.
      That’s the conundrum. So how does that work then.?

      Got an answer? Of course you haven’t, because there isn’t a scientific explanation based on natural processes.
      So how best to cope with that scenario.
      Well that’s easy, just pretend it doesn’t exist and ignore it.
      This is what is called wilful blindness.

      quote :

      But you refuses to accept that. You think that if something is nowadays composed from proteins, it had to be composed of proteins billions of years ago.

      Do you mean that I refuse to accept the so called RNA (world) hypothesis as a fact.
      If that is what you mean then you are correct.
      I do not accept hypothesises as fact until there is sufficient evidence to confirm them.
      The fact that this is still a hypothetical scenario even within the biological community, speaks for itself.

      btw cyanobacteria is regarded as the oldest living fossil and is dated to 3.5 billion years ago. And guess what, it contains proteins.
      http://www.ucmp.berkeley.edu/bacteria/cyanointro.html

    • #107097
      scottie
      Participant

      The conventional dating which provides the backdrop upon which all evolutionary theory is presented, reveals some interesting information regarding fossils.

      The fossils of cyanobacteria are particularly significant.
      http://books.google.co.uk/books?id=OKkT … &q&f=false

      Their ability to carry out oxygen producing photosynthesis is a universal characteristic of cyanobacteria that distinguishes it from all other prokaryotes.

      These fossils found in Western Australia are dated to at least 3.5 billion years ago.
      We don’t know as yet how much earlier they may have existed.
      However these prokaryotes are fully functional unicellular life with fully functioning transcription and translating systems manufacturing proteins, and of course they are still around today in huge quantities.

      Again according to conventional theory the earth is 4.5 billion years old.
      http://pubs.usgs.gov/gip/geotime/age.html
      And according to the same US Geological Survey the oldest dated rocks in Western Australia are 3.4- 3.6 billion years.

      This places the appearance of cyanobacteria around the same time as the appearance of the first rocks and therefore does not leave much if any time for any evolution to take place, let alone such a complicated life form as cyanobacteria which has the additional system of photosynthesis that other prokaryotes don’t.

      There is of course more to this.
      In the Jack Hills of Western Australia scientists have uncovered very interesting evidence of the early earth conditions over 4 billion years ago.

      quote :

      Deep in the Australian Outback under the sparse vegetation of the Jack Hills, scientists have uncovered secrets about conditions on the Earth over 4 billion years ago. Crystals within the rocks hint that the surface of the early Earth was cool and wet—not the roiling inferno that some theories and asteroid crater observations suggest
      Low and smoothed by erosion, the Jack Hills aren’t too impressive as a mountain range. But mineral crystals have weathered out of the Jack Hills and washed into streams, and these crystals tell a fascinating story about how far back in Earth’s past the oceans might have formed.

      http://earthobservatory.nasa.gov/Features/Zircon/
      http://earthobservatory.nasa.gov/Featur … ircon2.php

      So the evidence from the US government agencies is painting a picture of an early earth of oceans. A land mass then appearing and the first fully formed complex life appearing in the rocks around the same period.

      Where have we read this scenario before?

    • #107114
      JackBean
      Participant

      scottie, you should join another thread about23008.html I’m sure you will have lots to say in there.

    • #107141
      scottie
      Participant

      Thanks for the invite, but I think I’ll pass on this one.

      You may have not noticed this yet, but this thread is entitled "Theories – Origin of Life" not "philosophies of life".
      You do seem to display a problem with understanding language, but I am sure you are working on that as I hope you are also on biology!!

      I know you would love to get onto the subject of your religion but as I have said before, I don’t do religion. Sorry 🙂

    • #107143
      JackBean
      Participant

      Do you realize, that difference 0.1 billion of years is 100 millions of years? That’s even longer than the humankind is on Earth. That’s not long enough for you?
      So, if there is no evolution, the humans are as old as Earth, right?

      You still didn’t respond to my questions regarding the designer. Is he physical or rather something spiritual?

    • #107161
      scottie
      Participant
      quote :

      Do you realize, that difference 0.1 billion of years is 100 millions of years?

      Well congratulations at least you are getting your math correct.

      quote :

      That’s even longer than the humankind is on Earth.

      Now you are beginning to excel yourself. Well done.

      quote :

      That’s not long enough for you?

      Long enough for what?

      quote :

      So, if there is no evolution, the humans are as old as Earth, right?

      Really!!! From where did that perverse logic arrive?

      quote :

      You still didn’t respond to my questions regarding the designer. Is he physical or rather something spiritual?

      There you go again.
      I have already answered that question twice.

      here
      by scottie » Sat Sep 03, 2011 8:46 pm
      about14351-192.html

      and here
      by scottie » Tue Aug 30, 2011 12:16 pm
      about14351-192.html

      Next question please

    • #107168
      JackBean
      Participant

      You rather shouldn’t be arrogant and ironic abusing that you’re a native speaker.

      quote scottie:

      quote :

      So, if there is no evolution, the humans are as old as Earth, right?

      Really!!! From where did that perverse logic arrive?

      So, explain it to me. There is no evolution. Where did the humans come from?

    • #107232
      scottie
      Participant

      Well I am glad you appreciate what it is like be subjected to a little bit of sarcasm.
      Let me also remind you of your rather sarcastic post to me to join another thread.

      Also to threaten to block any further posts from others on another thread because you happen to disagree with them and even insult their religious belief, I found to be in very bad taste.

      I have always tried to be polite to you in all my posts and have even apologised when I have poked a little bit of fun, even though I was responding in kind to your own sarcastic questioning.

      I have always made it clear that I do not discus religion because of all the obvious emotions that manifest themselves, because when emotions take over truth is invariability a casualty.

      Now you clearly believe that evolution, (something that you still have not been prepared to explain in any detail) is the answer to the Origin of Life.

      I don’t have a problem with that, except that you insist that your belief is actual science.
      If you insist that your belief is founded in verifiable science then you must show that to be the case. Simply stating that it is a fact, is not science.

      Now let me try once again and answer your question

      quote :

      So, explain it to me. There is no evolution. Where did the humans come from?

      By referring you to my post to you on Tue Jul 26, 2011 10:16 am
      post-133083.html#p133083

      I explained very clearly my understanding of design and the reasons for it.
      I also asked that if you disagreed then to please explain where I was wrong.

      You chose not to respond to any further posts until I posted on Quorum sensing, when you responded on Sun Aug 07, 2011 8:09 am
      about14351-180.html
      I replied in great detail the following day at which point you again went silent until the 30th August when you jumped in again as the discussion had move on.

      All of this reveals to me that you don’t wish to debate your own views except to state that they are science, but keep looking for opportunities to find fault with someone else post.

      If that is your tactic then fair enough I have to live with it.
      However it only reveals to me that you do not have the confidence in your own view to debate it scientifically.

    • #107248
      JackBean
      Participant
      quote scottie:

      Well I am glad you appreciate what it is like be subjected to a little bit of sarcasm.
      Let me also remind you of your rather sarcastic post to me to join another thread.

      I have never insulted anyone for his or her English.

      quote scottie:

      Also to threaten to block any further posts from others on another thread because you happen to disagree with them and even insult their religious belief, I found to be in very bad taste.

      I have locked the topic because Tomn was saing all the time God made everything so how you want to discuss with someone like that? I would refer you to the biohazard’s post

      quote scottie:

      I have always tried to be polite to you in all my posts

      I know. You were always the good,polite guy with posts full of sarcasm.

      quote scottie:

      Now you clearly believe that evolution, (something that you still have not been prepared to explain in any detail) is the answer to the Origin of Life.

      No, I have already told you several times that evolution has nothing to do with the origin of life. As you stated correctly, Darwin wrote "On the origin of species" not "On the origin of life". What he was referring to, was diversification of species. It doesn’t matter that much how exactly evolution proceeds, but it still does.

      quote scottie:

      quote :

      So, explain it to me. There is no evolution. Where did the humans come from?

      By referring you to my post to you on Tue Jul 26, 2011 10:16 am
      post-133083.html#p133083

      I explained very clearly my understanding of design and the reasons for it.
      I also asked that if you disagreed then to please explain where I was wrong.

      You have not (repeatedly) answered my question. I asked where did humans come from. Where they designed as humans or did they evolve from "lower" organisms?

      quote scottie:

      All of this reveals to me that you don’t wish to debate your own views except to state that they are science, but keep looking for opportunities to find fault with someone else post.

      If that is your tactic then fair enough I have to live with it.
      However it only reveals to me that you do not have the confidence in your own view to debate it scientifically.

      So, when you look for mistakes in evolution (or rather darwinism), it is OK, but when evolutionist look for mistakes in creationism/IDism, it’s assault?

    • #107253
      JackBean
      Participant

      Since you mentioned your post about14351-180.html#p133485 I’ll try to reply.
      The DNA codes for many kinds or siRNA besides proteins. There is still increasing number of regulatory RNAs and together with the proteins they determine the regulation and organisation you’re referring to.

      from your other post about14351-192.html#p134037

      quote scottie:

      All our experience tells us that this king of information comes from a mind, one that is using “ an external source of free energy” as NASA puts it.

      You know, my English is as bad as my biology, would you be so kind to explain what you mean by mind? Can you show exactly where NASA speaks about some mind?

      quote scottie:

      Please reflect for a moment, on your own (canalon’s) statement

      quote :

      Science’s best bet is currently self replicating RNAs with catalytic activity, as those things can be observed

      Now apart from the fact that you aren’t keeping up with the latest understanding amongst scientists, you are reducing your view of science to a casino operation.

      Scientists with certain philosophical needs may engage in betting, science however is not a casino.

      This type of wishful speculation stems from a philosophical need.
      It has nothing to do with science and deep down I suspect you know it.
      ( Freeman Dyson sums it up nicely in a conclusion comment to his own speculative scenario on origins.
      “ The question is whether any of that makes sense. I think it does, but like all models, its going to be short-lived and soon replaced by something better.”)

      You know, that’s the difference between you and a real scientist. Scientist will never say he knows anything for 100%, we have hypothesis and theories for which we have proofs. On the other hand, you know exactly what the truth is, although you have no proof.

      quote Ashley Montague:

      Science has proof without any certainty. Creationists have certainty without any proof.
    • #107268
      scottie
      Participant
      quote :

      I have never insulted anyone for his or her English.

      No but you insult their belief. As a moderator on this forum you should be setting an example in being courteous.

      quote :

      I have locked the topic because Tomn was saing all the time God made everything so how you want to discuss with someone like that? I would refer you to the biohazard’s post

      I agree with biohazard that this is a scientific forum. I have said the same thing myself. What I haven’t done is insult Tomm through his religion. If you don’t like his post then don’t respond. Why should you stop others from responding, that smacks of censorship.

      quote :

      No, I have already told you several times that evolution has nothing to do with the origin of life. As you stated correctly, Darwin wrote “On the origin of species” not “On the origin of life”. What he was referring to, was diversification of species. It doesn’t matter that much how exactly evolution proceeds, but it still does.

      This thread is entitled “Theories – Origin of Life I would have thought that is clear enough.
      This was the first question.

      quote :

      I’m writing a paper on the origin of life,……..

      If you don’t want to discuss origin of life why are you posting on this thread?

      Also I have argued that the origin of life and origin of species is one and the same thing.and I have explained why.

      quote :

      You have not (repeatedly) answered my question. I asked where did humans come from. Where they designed as humans or did they evolve from “lower” organisms?

      I beg to differ, I have consistently argued that design is how humans and indeed species have come about.

      This is what I said to both you and Patrick
      JackBean » Tue Aug 30, 2011 12:51 pm
      about14351-192.html

      quote :

      It did not appear without guidance.
      All our experience tells us that this kind of guiding information comes from a mind.
      Is there any other logic we have experience to go on?
      If so please inform.

      I don’t see how much clearer I could have been.
      As you can see I asked for a response – You didn’t oblige

      The information that controls the cell operations in a human cell differs from the information content of cells from other species.
      Differentiation is simply one clear example of that. There are of course more examples.
      The Functional and indeed specified information found in cells is not the product of natural forces.
      The only known source of this type of information is from a mind.
      If you disagree then please inform me how else it can come about.?

      quote :

      The DNA codes for many kinds or siRNA besides proteins. There is still increasing number of regulatory RNAs and together with the proteins they determine the regulation and organisation you’re referring to.

      I don’t argue with that.
      The point I was making is that there are different levels of information regulating cells. Where those levels of information that reside in the cell are, is not known to science.
      Hence my argument, that changes in DNA only effect the type of protein manufactured, and usually to the detriment of the cell.
      That is why there is such an elaborate system of feedback and error correction in cell processes.

      This very system of error control is evidence in itself of design.

      I didn’t report NASA spoke about the mind. I said NASA acknowledged that “an external source of free energy” was required.

      I said that that external source can only come at the express will of a mind. In other words an outside agency is required to produce the design we see in the cell.

      I hope that is clear enough.

      quote :

      Scientist will never say he knows anything for 100%, we have hypothesis and theories for which we have proofs.

      I agree that a scientist should not say he knows 100%.
      When you say we have “ hypothesis and theories for which you have proof”
      That sounds like 100% to me.
      Also hypothesises are by definition not proven. When a body of information begins to support a hypothesis then, and only then may that hypothesis be elevated to the status of a theory.
      Every real scientist knows that.

      The RNA world idea is a hypothesis. It has not been elevated to the status of a theory because the evidence does not support it. This is what NASA was reporting on.

    • #107359
      scottie
      Participant

      Jackbean has argued that origin of species is not the same as the origin of life.
      These are two separate matters, and evolutionists only argue on the subject of origin of species.
      Now I have argued differently, stating that they are the same.

      However let’s assume Jackbean’s view is correct and see where that leads us.

      Now the data from the various DNA sequencing projects in animals and plants have revealed some quite surprising results.

      For example the genes found in a mouse are for the most part the same genes found in man. There may be slight differences but are clearly the same genes. The same with man and fish that are, for the most part also, the same genes. Even further than that, the Genes in man and chimpanzee are almost identical.
      Not only are the genes the same, but the base pairs in these genes are often identical.
      http://www.ornl.gov/sci/techresources/H … pgen.shtml

      We know that new proteins rarely evolve by point mutations in existing genes to create new genes.
      However there is this process called Exon Shuffling.

      After a mRNA sequence is transcribed from the chromosome, a protein called a Spliceosome will cut out sections of the gene sequence, these sections are known as Introns.

      What these Introns do is to break up the instructions for making the proteins. Therefore the Spliceosome has to cut out these sections of DNA and join the remaining pieces (Exons) together.
      This brings different protein domains together in the final protein when it is translated. Through this process, one gene may encode many different proteins.

      Here is an excellent visual of this process
      http://highered.mcgraw-hill.com/olcweb/ … cess%20RNA

      So to summarise
      Exons are the coding area in a genome that produce the genes that make proteins.
      Introns are stretches of DNA, within those coding areas, that have to be spliced out before the mRNA can be prepared for transport to the Ribosome for manufacturing protein.

      These Spliceosome Introns have been quite puzzling to biologists, because although they are numerous in Eukaryotes ( plant animal and human cells) we don’t observe them in Prokaryotes.

      Additionally some Eukaryotes like Yeast have a few of these while Humans have tens of thousands of them. The more complicated the organism the more Introns.

      So the puzzling question for biologists is to determine where these came from.

      When new information is required this is achieved by re-using existing information. This depends on the initial information and how this information must be shuffled in order to create new information.

      Exon shuffling and mRNA splicing are both highly complicated events in eukaryotes. However the primitive self-replicating cells, ie prokaryotes, cannot implement such a system.

      Not only do they lack the information to shuffle but they don’t have the machinery to shuffle it.

      Therefore the first gene could not have been created by re-arranging and shuffling existing information because there was no information or mechanism to shuffle and rearrange.

      Hence the additional puzzling questions that Biologists are trying to grapple with.
      How did the information and the machinery come about for gene creation in Eukaryotes?

      Remember that evolutionary theory posits that prokaryotes evolved into Eukaryotes by a process of random mutations of the genome and then filtered by the other process of Natural Selection. All of this cementing the other pillar of evolutionary theory – Common Ancestry.

      Here is a 2006 paper that tries to deal with this problem.
      It is entitled “Phase distribution of spliceosomal introns: implications for intron origin”
      http://www.biomedcentral.com/1471-2148/6/69
      This paper is also referenced by our very own biology online article here
      http://www.biology-online.org/articles/ … tract.html

      This paper examines two competing theories. ( I use the word theory loosely)

      One theory relies on an organism called a Progenote.
      Now what is a progenote?
      Well the progenote is a hypothetical candidate for the last universal cellular ancestor. There are two major conjectures associated with this entity: (1) the progenote’s genome is based on RNA rather than DNA and (2) the replication, transcription and translation of this RNA organism had a much higher error rate than the ensuing DNA-based cells.
      http://onlinelibrary.wiley.com/doi/10.1 … 3/abstract
      So here is one explanation that requires a mythical organism and then goes beyond that by having two major conjectures associated with it.
      And of course ones like me get berated for not calling this science. 🙂

      So what about the other “theory”
      Well I had better leave that to another post as this one is long enough.
      Don’t want to add to my “long-winded reputation” 🙂

    • #107361
      JackBean
      Participant

      Too bad, I was hoping this will fall away into the past, but you are obviously too bored, aren’t you?

      You’re permanently insulting your oponents for lack of biology knowledge and bad English. I was sarcastic to you because of your lack of simple logic, little bit of imagination, comprehention of your oponent’s arguments and overall lack of ability to discuss.
      Yeah, I have locked the topic. If you have problem with that, forward it upwards (the nick of moderator is honee_v).

      You are "discussing" theories of origin of life by arguing about Darwinism/evolution. So you should first think about it, whether is it connected or not.

      quote :

      This is what I said to both you and Patrick
      JackBean » Tue Aug 30, 2011 12:51 pm
      about14351-192.html

      I don’t see any such post.

      quote scottie:

      It did not appear without guidance.
      All our experience tells us that this kind of guiding information comes from a mind.
      Is there any other logic we have experience to go on?
      If so please inform.

      So, you again didn’t explain, what you mean by "mind". You know, you have to forgive to us poor, who not speak Engrisch.
      You have not again said, how did the humans appear on Earth. Try to read this carefully and pick one possibility (or come up with other, but do not start about lysosomes :roll:)
      1) they were created when all the other life on Earth was created few billions of years ago
      2) they were created few tens/hundreds thousands of years ago when the creator was bored again and had no forum to post on
      3) they evolved from lower animals, no matter, whether these were created or arose spontanneously

      quote scottie:

      quote :

      The DNA codes for many kinds or siRNA besides proteins. There is still increasing number of regulatory RNAs and together with the proteins they determine the regulation and organisation you’re referring to.

      I don’t argue with that.
      The point I was making is that there are different levels of information regulating cells. Where those levels of information that reside in the cell are, is not known to science.
      Hence my argument, that changes in DNA only effect the type of protein manufactured, and usually to the detriment of the cell.
      That is why there is such an elaborate system of feedback and error correction in cell processes.

      This is really like speaking with a retarded man. So you agree that DNA codes for regulating RNA and in the next sentence you write that changes in DNA affect only proteins.

      quote scot:

      I agree that a scientist should not say he knows 100%.
      When you say we have “ hypothesis and theories for which you have proof”
      That sounds like 100% to me.
      Also hypothesises are by definition not proven. When a body of information begins to support a hypothesis then, and only then may that hypothesis be elevated to the status of a theory.
      Every real scientist knows that.

      I will try it differently: hypothesis and theories for which we currently have proofs. Think about Newton, who saw the apple to fall down and came up with gravity. Einstein had more proofs and came with his theories. Now we may even find his theories false, since there were detected neutrinos faster than light.
      On the other hand, you (and Tomn) are definitely sure that you are right and noone can prove you wrong, because it would reaquire either imagination or logic.

      quote scot:

      We know that new proteins rarely evolve by point mutations in existing genes to create new genes.
      However there is this process called Exon Shuffling.

      Not true, there are gene duplications, which may further mutate.

      quote scot:

      This brings different protein domains together in the final protein when it is translated. Through this process, one gene may encode many different proteins.

      You’re obviously not much experienced with molecular biology, are you? Exons rarely code for separate domains. Also, these "many different proteins" are basically one protein with altered function.

      quote scot:

      Exon shuffling and mRNA splicing are both highly complicated events in eukaryotes. However the primitive self-replicating cells, ie prokaryotes, cannot implement such a system.

      Not only do they lack the information to shuffle but they don’t have the machinery to shuffle it.

      The last sentence is like saying "I’m human because I’m human". But back to prokaryotes. Yes, they lack the spliceosome system and they lack introns. They lack in general gene editing, although there are some exceptions such as Trypanosoma http://en.wikipedia.org/wiki/RNA_editin … r_deletion

      quote scot:

      Don’t want to add to my “long-winded reputation” 🙂

      sounds interestingly on the end of 745 words long post 😉

      Just one more thing, once you said, that Darwinism is not scientific theory, because it is not falsifiable. How is your theory (sorry, truth) falsifiable?

    • #107365
      Gavin
      Participant

      Science’s mandate is to fill in holes in our knowledge without invoking supernatural entities. Lots of holes left. Don’t despair. We’re making good progress.

    • #107417
      scottie
      Participant

      My sincere thanks to the moderators for allowing me back on the forum.

      Much appreciated.

    • #107429
      scottie
      Participant

      May I clarify some points from my last but one post.

      1) When I discussed “Exon Shuffling” in isolation, it was not intended to show that it was the only method of new information.
      I am fully aware of gene duplication as another method. In fact I believe I was the first to introduce it into this thread back in August.
      Here

      quote :

      scottie » Thu Aug 25, 2011 12:51 pm

      about14351-180.html
      and

      quote :

      scottie » Fri Aug 26, 2011 12:18 pm

      about14351-192.html

      The point I was making was that, there had to be existing splicesome introns to shuffle in Eukaryotes, plus of course the mechanism to shuffle those introns..
      As this is a vital process in transcription The question of how and where these introns and the shuffling mechanism came from is what the hypotheses I referred to were addressing.

      Now clearly the so called early theory is not preferred by the article this forum has cited.
      In fact the article prefers the late theory.
      It has it’s own set of difficulties but that is another story.

      2) Design theory is falsifiable.
      In a previous post I pointed to one way in which it would be falsifiable.

      quote :

      scottie » Tue Jun 21, 2011 10:20 pm

      about14351-144.html
      starting at this statement.

      quote :

      Is my understanding of Functional Design falsifiable?

      If this theory is falsifiable then it can seriously claim to be a scientific theory or hypothesis.
      I made it very clear how it can be falsified?

      That was in June of this year and no one has attempted to do just that.
      Now until that happens Design theory must still stand as a scientific theory or hypothesis.

      That is all I am claiming.

      I did end that post with a request as to what is falsifiable about current neo-Darwinian theory.

      As yet there has been no response.

      Hope that clear matters up.

    • #107431
      Gavin
      Participant
      quote scottie:

      I did end that post with a request as to what is falsifiable about current neo-Darwinian theory.

      If phylogenetic data, either morphological or molecular, were unable to build trees, or if the morphological data showed no relation to the molecular data.

    • #107456
      scottie
      Participant

      Let me see if I understand you correctly:-

      We can observe certain morphological characteristics in a particular group of taxa of say (plants) and use this data to draw conclusions about the evolutionary relationships between these organisms.

      Having observed morphological characteristics of this group of different plants we can now examine protein sequence in the same or related plant species to perform cladistic analysis.

      We can therefore compare the results of phylogenetic relationships obtained using protein sequences (molecular data) with the results obtained from using morphological data.

      For example if cactus (Schlumbergera truncata) and spike-moss (Selaginella) were in the group chosen we would note that they appear to have very similar leaf-like structures, but we would come up with very different evolutionary origins in the molecular data.

      How does this support or falsify evolutionary theory. I don’t understand your point.
      Could you clarify please?

      There is of course controversy within the evolutionary community on the value of morphology in producing lines of decent.

    • #107459
      Gavin
      Participant
      quote scottie:

      How does this support or falsify evolutionary theory. I don’t understand your point.

      Something about descent with modification. If trees can be built, this supposition is supported. If trees cannot be built, the supposition is falsified. Phenetics has often proven unreliable.

    • #107463
      JackBean
      Participant

      hey scottie, are you OK? Just one post after weekend? Are you ill or something?

      Again, you’re referring to post, which I cannot find. Can you copy at least like 5 first lines, so that I can find it? Or click on the name of your post and then copy the link about14351-144.html#p132383 so it will lead directly to your post.
      Otherwise I will consider that as refusal to answer the questions.

      And I’m also waiting for the answer concerning human origin.

    • #107497
      scottie
      Participant

      Gavin

      quote :

      Something about descent with modification. If trees can be built, this supposition is supported. If trees cannot be built, the supposition is falsified. Phenetics has often proven unreliable.

      There are different views on which is the more reliable Phenetics v Cladistics

      But thanks your view is now clearer.

      Decent with modification
      Or as Richard Dawkins put it in his book
      Unweaving the Rainbow: Science, Delusion, and the Appetite for Wonder, p. 201.

      quote :

      What had been distinct species within one genus become, in the fullness of
      time, distinct genera within one family. Later, families will be found to have diverged to the point where taxonomists (specialists in classification) prefer to call them orders, then classes, then phyla…Ancestors of two different phyla, say vertebrates and molluscs, which we see as built upon utterly different ‘fundamental body plans’ were once just two species within a genus.

      If that is what you mean then,
      Yes, that would and indeed does make the theory falsifiable.
      So a tree arrived at cladistically showing decent with modification would be one such way to test the data. If a tree cannot be produced then that would constitute falsification.
      That’s a good test.

      Jackbean
      I think you really are quite a nice person, who is trying very hard to be obnoxious.
      But you do need to get more practice in. 🙂

    • #107499
      JackBean
      Participant

      so now I’m a nice person? But you have changed significantly since I was away.

      Yet, you’re still not responding the answers, are you?

    • #107526
      scottie
      Participant

      Gavin
      Organisms such as Trilobites of the Phylum Arthropoda, have articulated body plans, intricate nervous systems and compound eyes. They first appear fully formed at the beginning of the Cambrian strata along with many other phyla of equal complexity.

      Aware of this himself Darwin in his “Origin..” stated

      quote :

      “The case at present must remain inexplicable; and may be truly urged as a valid argument against the views here entertained.”

      (ie his views were falsifiable then)

      In his 1987 book the “The Blind Watchmaker” page 229 Richard Dawkins comment on this is

      quote :

      “It is as though they [the invertebrate phyla] were just planted there, without any evolutionary history”

      In a their 1987 paper titled “Interpreting Great Developmental Experiments: The Fossil Record, paleontologists J.W. Valentine and D.H. Erwin. noted

      quote :

      “transitional alliances are unknown or unconfirmed for any of the [Cambrian] phyla and yet . . .the evolutionary explosion near the beginning of Cambrian time was real and produced numerous [new] body plans.”

      In view of the above observations by these recognized authorities, can a tree of “decent with modifications” now be constructed for these organisms that suddenly appeared in the strata of the Cambrian?

    • #107529
      JackBean
      Participant

      Well, there is no need for further discussion, if you persist to refuse to answer to my questions, isn’t it?

    • #107534
      Gavin
      Participant
      quote scottie:

      In view of the above observations by these recognized authorities, can a tree of “decent with modifications” now be constructed for these organisms that suddenly appeared in the strata of the Cambrian?

      I encourage you to read (from beginning to end) your quoted sources, particularly the first two, and to research the Cambrian explosion beyond creationist websites. This topic has been dealt with ad nauseam, and I have no desire to rehash it here. Also, do a search on YouTube for the following terms: "Cambrian explosion", "quote mining", and "Dawkins" – I once came across an amusing short video of Dawkins dealing with the use of quote mining by people such as yourself.

    • #107537
      JackBean
      Participant

      well, well, well, scottie, it seems, that there are coming clouds over your being here. I have always suspected you twist the meaning of all the quotes you always add (as was the example with NASA saying something about mind, right) and here you got right into your trap:

      quote scottie:

      In his 1987 book the “The Blind Watchmaker” page 229 Richard Dawkins comment on this is

      quote :

      “It is as though they [the invertebrate phyla] were just planted there, without any evolutionary history”

      Apparently, this is a well known example http://rationalwiki.org/wiki/Quote_mini … ndex_-_QMI

    • #107556
      scottie
      Participant

      Gavin

      I take it then that a tree cannot be constructed.

      I don’t need to quote mine as is suggested because I have read Dawkin’s books. Though I do find books on religion and philosophy quite tedious.

      I have also read Origins and have found that much more interesting.

      The Cambrian phyla appeared without any Precursors and that is why eminent biologists like Wray, Levinton and Shapiro have attempted to provide molecular evidence for a common ancestor.

      There is a clue for you.

      Much more interesting than you tube videos.

    • #107557
      Gavin
      Participant
      quote Gavin:

      This topic has been dealt with ad nauseam, and I have no desire to rehash it here.
    • #107592
      JackBean
      Participant

      scottie: so you won’t comment on the quote mining and you won’t answer my questions, right? Well, then I don’t see any reason why to keep this thread ongoing. So you should deal with the opened problems or I will lock it here.

    • #107593
      Gavin
      Participant

      Scottie. You are, of course, free to be selective in what and in whom you choose to believe. Lots of people have said lots of things, not all of which is true. Talk, as the saying goes, is cheap. Gould had his opinions that not everyone shares. I’d be interested in seeing some support for:

      quote scottie:

      very complicated phyla appeared in Cambrian strata without any precursors. In other words no prior speciation, they just arrived.

      It’s a bold statement that needs some backup. Do you have any evidence that these phyla "just arrived".

    • #107645
      JackBean
      Participant

      scottie, you gave me no other choice, since you still refuses to answer, I have locked this topic. If will you ever change your mind, let me know.

    • #107991
      scottie
      Participant

      Canolan
      Thank you for unlocking this thread.

      Whether it’s humans, Trilobites, Brachiopods or any other form of life,there is no scientific answer.
      There are only hypotheses.

      However from the evidence of the Cambrian strata complex multi=celled creatures first appeared around 550 million years or so, ago according to conventional dating. There is no evidence of precursors.

      Certainly no evidence of human fossils have been found in this strata as far as I am aware.
      I can only conclude that humans first appeared sometime after that.

      Gavin
      I will be able to respond to your question in the next post. It will be a little later as I have to be elsewhere for the next few hours or so.

    • #107992
      JackBean
      Participant

      so humans evolved from "lower creatures"?

    • #108039
      scottie
      Participant
      quote :

      so humans evolved from “lower creatures”?

      I have been arguing against this. I thought that point has been well established.

      I don’t accept humans evolved from any other life form.
      One of the lines lines of evidence to support my argument is the fossil data from the cambrian radiation.
      The sudden arrival of multi celled organisms with basic individual body plans.
      After some 150 years of searching no precursors have been found in any lower strata, which of course mitigates against common ancestry.
      Without common ancestry where does macro evolutionary theory, in whatever form, stand?

    • #108040
      scottie
      Participant

      Gavin
      You raise a valid point regarding Stephen Gould’s view of Punctuated Equilibrium. There are of course several others with their own hypotheses as to how the process of macro evolution works.

      Carl Woese with his hypothesis of an early era of considerable Horizontal gene transfer.
      Simon Conway Morris with his idea of “front loaded” evolution
      Lynn Margulis — Endosymbiotic theory
      James Shapiro — Natural genetic Engineering
      I could keep on with such leading names as, Allen Orr, Daniel Dennett, PZ Myers, Michael Ruse Coyne etc etc, All tearing lumps out of each other. Their email exchanges can be quite vitriolic at times.
      Freeman Dyson and Richard Dawkins can’t even agree with each other as to what Darwin’s theory actually is.
      These of course are all evolutionary scientists and philosophers.

      So who is right?
      They can’t all be right.

      That is why I have repeatedly asked the question without response, as to what particular version of evolutionary theory ones opposing me subscribe to.

      Well under all this rhetoric there is a body of evidence that no one has been able to explain.

      In part I am referring of course to the Phyla radiation in the Cambrian strata.
      This is solid evidence.
      You appear to ask the question if I can prove the non existence of these precursors.
      Well how do you prove something doesn’t exist if it has never been found.

      However Erwin’s paper that I have referred to does provide some interesting new thinking on the subject.

    • #108041
      JackBean
      Participant

      so humans were created about 40 thousands years ago?

    • #108042
      Gavin
      Participant

      Scottie,

      I guess you didn’t follow my suggestion of doing some research into the Cambrian explosion (avoiding any sources from religious organisations). I still encourage you to do so, but I’ll just make a few pertinent points here:

      1) very few organisms fossilise, especially those without hard parts, which means,
      2) the fossil record has gaps, and always will, because, in part, of 1),
      3) gaps in the fossil record do not represent the falsification of evolution, they just represent gaps in the fossil record.

      quote scottie:

      You appear to ask the question if I can prove the non existence of these precursors.
      Well how do you prove something doesn’t exist if it has never been found.

      Exactly! In science, falsification requires evidence, not lack of evidence. As the old and worn saying goes, absence of evidence is not evidence of absence. When all the fossils that have ever formed have been found, get back to us. And all the parts of the tree of life that strongly support common ancestry (and not just animals) mean what, exactly?

      quote :

      That is why I have repeatedly asked the question without response, as to what particular version of evolutionary theory ones opposing me subscribe to.

      All views of scientific evolutionary theory oppose your view of creation. Different opinions exist because science is not autocratic. Science is a work in progress, and always will be.

    • #108043
      Crucible
      Participant
      quote Gavin:

      Scottie,

      All views of scientific evolutionary theory oppose your view of creation. Different opinions exist because science is not autocratic. Science is a work in progress, and always will be.

      Does science investigate Creation ? Can you expand on how views of scientific evolutionary theory oppose it ?
      Would you view the kind of evolutionary science you are talking about, as a battleground where opposing views are to be kept out by mud slinging, marginalization tactics, name calling, and deprecation of character ?

    • #108044
      Gavin
      Participant
      quote Crucible:

      Does science investigate Creation ? Can you expand on how views of scientific evolutionary theory oppose it ?

      You have come on this forum because you believe that evolution is false. The onus is not on us to defend evolution. A decent library will do that. The onus is on you to falsify it.

    • #108045
      Crucible
      Participant
      quote Gavin:

      quote Crucible:

      Does science investigate Creation ? Can you expand on how views of scientific evolutionary theory oppose it ?

      You have come on this forum because you believe that evolution is false. The onus is not on us to defend evolution. A decent library will do that. The onus is on you to falsify it.

      That’s absolutely false. Evolution is self-evident. I do not believe in Creation or ID.

      The answer was not responsive to any of the questions asked. Noted.

    • #108046
      Gavin
      Participant
      quote Crucible:

      I do not believe in Creation or ID.

      Good for you.

      quote :

      The answer was not responsive to any of the questions asked.

      Okay, okay. The existence of gods cannot be falsified by science, but little evidence supports it. I have no desire to present the evidence supporting evolution. As I said, any decent library can do that.

    • #108047
      Crucible
      Participant

      I’m not sure who is denying that evolution occurs. Not me. There could be questioning of some basic particulars, assumptions or tenets, though, in the theory as propounded by Neo Darwinian gene-centrist proponents.

    • #108048
      Gavin
      Participant

      I’m sorry if I mistook you for a denier. We get some here, and I sometimes (OK, often) lose track of who accepts this but rejects that, and why.

    • #108049
      Crucible
      Participant
      quote Gavin:

      I’m sorry if I mistook you for a denier. We get some here, and I sometimes (OK, often) lose track of who accepts this but rejects that, and why.

      If you’re a Dawkins fan you might well call me a "denier". These people have such labels for those who do not agree absolutely with him, on certain particulars.

    • #108101
      scottie
      Participant

      Gavin
      Sorry for delay but I have been away over the weekend.

      quote :

      I guess you didn’t follow my suggestion of doing some research into the Cambrian explosion (avoiding any sources from religious organisations).

      I do recall this encouragement to me, however I assumed you were confusing me with someone else. As I have said before I don’t do religion.

      Now surely you are not suggestion that Douglas H. Erwin whose paper I have referenced is writing for a religious organisation?
      Or that the Smithsonian a religious organisation?
      Again are you suggesting that ones like James Valentine of University of Berkeley is a religionist or that Berkeley is a religious organisation.
      Please lets not invent strawman arguments.

      Let me though, take your points in turn
      1 & 2

      quote :

      very few organisms fossilise, especially those without hard parts

      It is true that shelled creatures leave a more extensive record than their soft-bodied
      counterparts. However you are aware are you not, that fossils of soft body organisms do appear quite extensively in the Cambrian layer.
      Soft-bodied phyla, such as Annelida, Onycophora and Priapulida, which do not have mineralized skeletons, make their appearance in the early Cambrian of Chengjiang, Yunnan Province in China..
      The Mid Cambrian Burgess Shale fauna from British Columbia, preserves many soft-bodied fossils similar to those of the Chengjiang fauna. This indicates that these forms were widespread and persisted for many millions of years. These faunas only serve to emphasize the spectacular diversity that was achieved so early in animal history
      Indeed cyanobacteria (ie soft body organism) are dated at some 3.5 billion years.

      So to suggest, as an argument, that the fossil record has gaps because soft body organisims don’t fossilise, clearly lacks credibility.

      quote :

      3) gaps in the fossil record do not represent the falsification of evolution, they just represent gaps in the fossil record.

      Did you not state this as evidence of falsification.

      quote :

      If phylogenetic data, either morphological or molecular, were unable to build trees, or if the morphological data showed no relation to the molecular data.

      When I produce evidence of the inability to produce a tree, you start to argue gaps.
      Can a tree be produced or can’t it, at least for the present?
      What is wrong with an admission that it can’t, at the present.

      Instead of course you accuse me of researching religious data, which clearly I was not and you know full well I wasn’t.
      In fact I am the one referencing peer reviewed papers from the evolutionary community.
      Please advise, when have you referred me to a peer reviewed paper?

      I simply report what evolutionary biologists themselves are acknowledging about the lack of precursors.
      You seem to forget what Darwin himself acknowledged. And he was the originator of this idea. (well almost).

      So then as I understand it, this is your view of science.

      quote :

      Exactly! In science, falsification requires evidence, not lack of evidence

      So when some organism suddenly appears fully formed in the fossil record, this is not considered evidence of, some organism having suddenly appeared.
      It is considered as a lack of evidence, that it had precursors.

      I have to assume this is your line of argument since you go on to state

      quote :

      As the old and worn saying goes, absence of evidence is not evidence of absence.

      It seems to me that while this "the old and worn saying " may be true, some further steps have to be taken to prevent this statement from becoming something like
      "You can posit any hypothesis whatsoever for which no definitively contradicting (or falsifying) evidence can be found".
      Now there are clear dangers connected with such an attitude.

      Hypotheses, by their very nature, contain the very elements of their own potential falsification. You cannot assert a well posited hypothesis without also revealing the ground on which the hypothesis may be refuted.

      I genuinely thought that you did just that initially. Sadly however you have resorted to a debating tactic rather than relying on science.

      Perhaps I could conclude this point with Karl Poppers observations

      quote :

      “Some genuinely testable theories, when found to be false, are still upheld by their admirers — for example by introducing ad hoc some auxiliary assumption, or by reinterpreting the theory ad hoc in such a way that it escapes refutation. Such a procedure is always possible, but it rescues the theory from refutation only at the price of destroying, or at least lowering, its scientific status. (I later described such a rescuing operation as a “conventionalist twist” or a “conventionalist stratagem.”)

      Karl Popper, Conjectures and Refutations,
      http://philosophyfaculty.ucsd.edu/facul … rphil1.pdf

    • #108102
      Gavin
      Participant

      Here’s how science works. Pay attention. Observations are made. Hypotheses are presented that attempt to explain the observations. If a verifiable observation falsifies an hypothesis, the hypothesis must be rejected or revised. You oppose evolutionary theory. What observations do you have that falsify evolution? An incomplete fossil record IS NOT AN OBSERVATION. What you will not understand (i.e. won’t accept) is that gaps in the fossil record do not falsify evolution. THEY ARE ONLY GAPS.

      Outside my window I can see no airplanes in the sky. This is evidence that there are no airplanes in my field of view. Not proof, but evidence. Maybe there is an airplane within my field of view, but it is too far away for me to see. Maybe there’s one behind that cloud. It is not very good evidence that airplanes do not exist. If I do see an airplane, that’s pretty solid evidence that airplanes do exist. Do you see the difference between an observation and the lack of an observation as evidence of something?

      Again, what about the rest of the tree of life?

    • #108103
      JackBean
      Participant

      scottie, again not responding?

    • #108127
      zombiesagan
      Participant

      Not only is the existence of gaps a faulty argument against evolution, as Gavin just explained, but it is nearly impossible to produce an evolutionary progression on our world without gaps. Finding a "missing link" closes a gap but creates two smaller gaps on either side of it. In order to close every "gap" completely we would need nearly every organism in a line of descent, as each descendant probably had some minor variations with the generation above it. This is impossible when fossils are so hard to come by.

      But that does not mean that all those gaps disprove evolution! In fact, another important part of a scientific theory is its predictive ability. Time and again evolutionary scientists have predicted that we should find an intermediate "missing link" organism in this area of the fossil record with these traits and paleontologists have found exactly those predictions. Evolution is a very powerful and fully scientific theory.

    • #108154
      scottie
      Participant

      Gavin

      quote :

      Here’s how science works. Pay attention. Observations are made. Hypotheses are presented that attempt to explain the observations.

      So let me get this right
      Evolutionary theory is now only a hypothesis. Is that what you are saying?

      Well if that is case then I agree with you.

    • #108158
      Gavin
      Participant

      Scottie

      There’s not much point in any further discussion about science and evidence. What I’m curious about is why you oppose evolution. Those who do are usually religious, but you say you believe in no gods. At least in no theistic gods. Are you a deist? But most versions of deistic gods just create the universe and then sit back and let it do its thing, including cosmic and biological evolution. I just can’t believe that you are an atheist who opposes evolution because of a lack of evidence. Would you mind stating (in 25 words or fewer) your version of things so we can understand where you’re coming from?

    • #108175
      zombiesagan
      Participant
      quote scottie:

      So let me get this right
      Evolutionary theory is now only a hypothesis. Is that what you are saying?

      Well if that is case then I agree with you.

      Evolution by natural selection was a hypothesis, but a hypothesis which accurately explains the observed data and phenomenon and makes predictions which come true becomes a theory. Evolutionary theory explains all the data and phenomenon we have so far observed and has even made predictions which have come true (both in the lab and in the fossil record).

    • #108177
      scottie
      Participant

      Gavin
      I don’t think I can stick to 25 words or fewer, so please bear with me.

      Firstly I don’t oppose evolution in the strict meaning of change over time, by whaterver natural means. Evolution in that limited sense happens.

      What I don’t accept is that this natural course of change over time as described above produces new species. In other words Darwin’s hypothesis is being shown to be wrong.

      Design is what I see the biological world revealing.

      Now if that design can be explained through natural processes then I have no problem in accepting that. Otherwise that design must be by some outside agency.
      This is not a religious question to me.
      I think for myself I don’t need or desire for the dogmas of others, be they religious or scientific.

      The only belief system I rely on is the scientific method.
      This essentially involves four steps:
      There are Observations,
      Then the formulation of a Hypotheses to explain the observation.
      That produces a Predictive capability.
      And finally devise Experiments to test the hypothesis.

      Now if that method does not provide the data in support, then at best, the hypothesis is not proven (in the scientific sense) and so remains a hypothesis.

      If data can be shown to support, then depending on the quality or quantity of that data the hypothesis may be elevated to the status of a theory,

      I have not seen any evidence that Darwinian (or Neo Darwinian) views fits the status of a theory. It is simply a hypothesis. The Cambrian fossils are but just one example of data not fitting the hypothesis. There are of course several other lines of data that my posts have referred to.

      If there is evidence then point me to it, ie peer reviewed papers, and I will certainly examine them.
      Statements like "evolution is proven" is not evidence. They are just statements unless accompanied by evidence.
      What I have seen in this discussion are the philosophical and religious views dominating over the actual data. A lot of heat but very little light.
      That is why I got involved on this forum.
      I am quite happy to answer any other questions you may have.

    • #108182
      Gavin
      Participant
      quote scottie:

      I don’t think I can stick to 25 words or fewer

      Yes, we know. Are you a philosopher? They are notorious for being poor communicators. They are also notorious for being scientifically illiterate. You are obviously not scientifically illiterate.

      Here’s my version: I know squat for sure, but the evidence seems to favour a Darwinian process for the production of new species. (20 words)

      Believe it or not, but we may actually be partial allies. I’m a relative hardliner when it comes to absolutes, such as claims of absolute truth. I’m generally a Dawkins fan but cringe a little when he continually says "evolution is a fact" or when Coyne writes a book called "Why evolution is true" (I haven’t read it yet). The word "proof" is horribly abused in all human endeavours. Proof outside of mathematics is a rare thing indeed, and even within mathematics, proof is only claimed given a certain set of unproven axioms. I try to avoid the word "proof" altogether, and in lieu of "fact" and "true", prefer "very likely a fact" and "very likely true". My view is that science can, at best, help to determine the probability of truth.

      Your reluctance to clearly state your position finally forced me to visit earlier postings to this thread to try to determine your position. You have stated that you believe in the veracity of science. So do I. You have also stated that you accept an evolutionary process occurring within species but not as a process that can produce new species. You seem to believe that design can be seen in nature, but that design has not arisen by a materialistic process. This implies that you believe in a nonmaterial designer. I am an atheist. Some atheists don’t like using the word "believe", because they say that belief implies faith, and they don’t like using the word "faith", because it implies religious faith. I’m not so queasy about using these words. Since I am a bit queasy about using the words "fact", "true", and "proof", and I have to use words to communicate my position, I say I believe something or have faith in something, meaning that the evidence to date supports the likelihood of that something being true.

      The scientific method, in an organised manner, has been applied for only a few centuries. It has helped us to come to a better understanding of many things. But we do not know how much we do not know. Duh. Hence, my beliefs remain conditional. And this is where probability enters my picture.

      Back to evolution. Your stance is that new species do not arise through a Darwinian process – no observation has indicated that any have. I know that various claims have been made that speciation has occurred within historical times or has been observed. Let’s not debate this issue but, for the sake of argument, say that no speciation has been observed to occur through a Darwinian process. Your stance seems to be that species can arise by a nonmaterial process. So for you to deny the origin of species through a Darwinian process, and for me to accept it, we both have to make a "leap of faith". A leap to the potential belief in a nonmaterial designer is a rather large leap, given the amount of evidence supporting it. My leap, that the Darwinian process that occurs within species (that you say you accept) can be extrapolated to the origin of new species, is rather small by comparison.

      I think this is where we differ. You are comfortable within your scientific veracity to entertain a large leap, and I am not. The probability thing gets in my way. So it seems that you either believe in a nonmaterial designer or you have no opinion one way or the other, i.e. you are a sceptic (you still haven’t clarified this point). The latter is fine for an ultra-strict interpretation of the data or as a purely philosophical stance, but as the saying goes, if it looks like a duck and quacks like a duck, it’s probably a duck. Sorry for trying to force a label on you, but labels exist as an aid to communication and understanding. If you’re in a class of one, I still don’t understand what that class is.

    • #108187
      zombiesagan
      Participant
      quote Gavin:

      A leap to the potential belief in a nonmaterial designer is a rather large leap, given the amount of evidence supporting it. My leap, that the Darwinian process that occurs within species (that you say you accept) can be extrapolated to the origin of new species, is rather small by comparison.

      I really like the way you put that. Exactly my thoughts as well.


      @Scottie
      : And if you’ve ever listened in on the debate about where to draw the line between certain species (the debate on how to classify early hominid remains for example), you’d realize that ‘species’ is really an artificial concept constructed in the human mind. Believing in evolution within a species but not believing that evolution can create new species is a weird belief. Where do draw the line? If you believe that evolution can occur within a species, why can’t that species experience enough change that we would call it a new species? I guess I’m just a little confused on your position.

    • #108188
      Gavin
      Participant
      quote zombiesagan:

      ‘species’ is really an artificial concept constructed in the human mind. Believing in evolution within a species but not believing that evolution can create new species is a weird belief.

      Also a very good point. The "accept micro- but reject macroevolution" camp might well ponder this.

    • #108191
      aptitude
      Participant

      scottie, you have consistently stated that you will not believe something because it is
      "just a hypothesis". I don’t think you realize that the first step of the scientific method is to make a hypothesis. So, according to your judgement, if every hypothesis is not worthy of consideration and false, the scientific method becomes useless?

      From wikipedia:
      A hypothesis (from Greek ὑπόθεσις; plural hypotheses) is a proposed explanation for a phenomenon. The term derives from the Greek, ὑποτιθέναι – hypotithenai meaning "to put under" or "to suppose".[1] For a hypothesis to be put forward as a scientific hypothesis, the scientific method requires that one can test it. Scientists generally base scientific hypotheses on previous observations that cannot satisfactorily be explained with the available scientific theories. Even though the words "hypothesis" and "theory" are often used synonymously, a scientific hypothesis is not the same as a scientific theory. A working hypothesis is a provisionally accepted hypothesis proposed for further research.[1]

      Every theory must initially be a hypothesis. If the theory matches all the criteria necessary to be a theory, such as evidence, predictability, and consistency, then it becomes a theory. Your belief that the organisms on Earth are designed is a hypothesis as well. If it matches sufficient criteria, we will consider it a theory.

    • #108217
      Crucible
      Participant
      quote aptitude:

      scottie, you have consistently stated that you will not believe something because it is
      “just a hypothesis”. I don’t think you realize that the first step of the scientific method is to make a hypothesis. So, according to your judgement, if every hypothesis is not worthy of consideration and false, the scientific method becomes useless?

      That’s a bit confusing. Which did he say ?
      a )Doesn’t necessarily believe a hypothesis because it’s only a hypothesis, or
      b) Will not consider any and they are all false ?

    • #108222
      Crucible
      Participant
      quote zombiesagan:

      quote scottie:

      So let me get this right
      Evolutionary theory is now only a hypothesis. Is that what you are saying?

      Well if that is case then I agree with you.

      Evolution by natural selection was a hypothesis, but a hypothesis which accurately explains the observed data and phenomenon and makes predictions which come true becomes a theory. Evolutionary theory explains all the data and phenomenon we have so far observed and has even made predictions which have come true (both in the lab and in the fossil record).

      quote :

      Evolutionary theory explains all the data and phenomenon we have so far observed and has even made predictions which have come true (both in the lab and in the fossil record).

      In your estimation, which of these is true, or synonymous in meaning, to your words ? That you think it has explained, can explain, would explain, does explain…?

      I’ve had a "scientist" tell me (after rebuttal) , that he only said "would explain", not "did explain" or "does explain". Do you see any difference in intent in wording, between these ?

      Are you saying everything observed has been explained ?

    • #108224
      scottie
      Participant

      Gavin
      I am sorry for the delay but I have an illness in the family and I, at this moment cannot devote much time to this discussion.

      I am a communications engineer (retired).

      I hope, that probably will indicate I try to remain grounded in the world of what can happen or indeed is possible, in the light of our current understanding of the world around us.

      My belief in the scientific method as I have explained is something I try and apply to all matters in life that require evidence to formulate opinions. I try not to have a preconceived bias when examining any matter.
      That is why I am definitely not a philosopher 🙂

      It is my belief in this scientific method, that has led me to accept the evidence that a only a mind can be responsible for the life processes we see all around us.

      That is not to say that a mind in a material body cannot create a new species.
      Craig Venter and his team have in a small way has done just that. It was his mind and that of his team that made what they accomplished possible. They did not create life itself but managed to create a new species.

      What they did serves only to highlight my acceptance that a mind must be involved in the creation of species. I see no evidence that natural forces have that capability. That is why I have continued to refer to the peer reviewed papers of scientists.

      I also accept that you can draw legitimate conclusions by way of circumstantial evidence.

      So returning the question of Darwinism, is it a fact or is it a hypothesis.
      Well it certainly is a hypothesis and indeed could reasonably be regarded as a scientific hypothesis. In fact in Darwin’s day it could have reasonably have been regarded as a null hypothesis.

      I find however that the accumulating evidence opposes that hypothesis and I have tried to present that evidence.

      Can I prove that a non material mind is responsible for life?
      No I can’t, what I can do is to present the evidence that circumstantially draws me to that conclusion.

      I did not grow up in a religious household and I don’t regard myself as a religiously inclined person. I have too much evidence around me to see the damage that organised religion has done. The same goes for organised atheism.

      I don’t have any objection to organisations per se. I just always keep in mind that the evidence shows that we don’t have the capacity to successfully organise our own affairs. The thousand of years of human history demonstrates that so clearly that I regard it as a fact.

      Yes I believe we are indeed partial allies.

    • #108230
      Gavin
      Participant

      Scottie. Thank you for making your position clear, at least to me. Amongst other labels, I consider myself an Occamist.

      We mortals face two "Big Questions" – the origin of the universe (or multiverse, or whatever) and the origin of life. Evidence is totally lacking for both, so for us to have an opinion or belief about them, we have to make a leap of some magnitude or other.

      For the origin of the universe, some physicists propose an extrapolation from the very small to the very large – the popping in and out of "existence" ("limits of detection" might be a better term) of virtual particles as a mechanism for the origin of the universe. I guess that’s the best we can do at present without invoking a deity of some sort. As a fellow old fart, I doubt much progress will be made on this front within my lifetime. Occam is not much help here. For the scientific method to be a valid means of accumulating data, though, it has to assume that observations are not the result of "outside" influences. The creation of the universe by a mind or from nothing are both rather bold proposals. I only prefer the latter due my inability to entertain the former.

      For the origin of life, various ideas have been proposed that are testable for the mechanisms involved but not for whether or not these mechanisms actually occurred (on Earth). I doubt that any test for what actually occurred is even possible, so we will probably never find sufficiently strong evidence to favour one idea over another, although I think that in order to avoid invoking an outside influence, it would have to involve an abiotic Darwinian process (selection) of some sort. For me, a materialistic process seems more likely than a supernatural one.

      For the origin of species, I can only defer to my previous argument of the magnitude of any leap that may be required. The question is not of the scale as the above two. We have pretty solid evidence that evolution occurs. Here, the extrapolation from the small to the large seems far less troublesome than what the physicists have to deal with. Occam, I think, would agree. I doubt that this leap could be the origin of your belief in some sort of cosmic mind, considering the larger issues mentioned above. I personally cannot get my head around the concept of a cosmic mind (circumstantial evidence cannot justify such a large leap), but I would choose that option over any form of a theistic god if only two options were available. But I choose the third option, just because it makes the most sense to me. The thought of a purely naturalistic, purposeless origin for everything also seems to be very comforting to me. But then I’m quite irresponsible – if there’s no cosmic purpose, then I’m off the hook for pulling my weight.

      quote scottie:

      I don’t have any objection to organisations per se. I just always keep in mind that the evidence shows that we don’t have the capacity to successfully organise our own affairs. The thousand of years of human history demonstrates that so clearly that I regard it as a fact.

      I don’t know about that. Without any speciation occurring, we have come a long way. You can’t possibly believe that we are no more organised today than our hunter-gatherer ancestors were a hundred thousand years ago. Biologically we may not have changed much, but culturally? Sometimes I think that you just like pulling our chains.

    • #108236
      Nick7
      Participant

      I’ve read the entire thread (well, maybe about 80-ish% of it… skipping Russian translations, etc…) – that was one HELL of a ride. I have NO idea how Scottie managed to withstand the pressure for so long, but I want to sincerely thank him for very interesting links, ideas and reasoning. I was also impressed by Gavin’s elegant summary.

      While I’m not in the position to judge the conclusions drawn by Scottie, it was interesting to see some arguments used against Scottie’s logic (or an absence of one, in case you are in the opposite camp). At the end, it frequently rolled down to:

      – Who is the designer?

      – Who designed the designer?

      – Why majority of scientist do not share your views?

      I still fail to comprehend why it is absolutely necessary to present a complete alternative to the dominant view to be even considered being a serious debater? For 29 pages people demanded the declarations of Scottie’s alternative. What the alternative can possibly be? A Flying Spaghetti Monster, obviously. But what would’ve happened if a Flying Spaghetti Monster appeared out of the shadow – Neo would’ve been unplugged from the Matrix and got flushed down the toilet without any need to spend any time on him (hence, on my opinion, Scotties reluctance to make any official declaration on the matter). So what’s the big deal if no well shaped alternative is offered… How about denials of Dark Matter, for example? Do those scientists have to be stripped of their degrees and sent back to school for just disagreeing with the mainstream believes? They are still the scientists, right? They earned the right to have a voice.
      There were a lot of legit links presented – I listened to a lot of Dawkins; let me listen to something different for a change.

      And this thing – who designed the designer? According to my observations, this one is always used as a final Ace up one’s sleeve when the conversation hits the roadblock, because it supposed to send a poor Flying Spaghetti Monster into a rotating loop.
      I saw a very good movie ones – Contact. There the humanity received a signal with 60,000 pages of complex data from ET life in the area of the star Vega. Nobody was able to crack it, until one guy realized what the problem was – we think like humans ( http://www.youtube.com/watch?v=2kYRvABhHAY ). We are the products of the world that we live in, and all our understanding of reality is bound by the properties of this world – a son is supposed to have a father, just like a father is supposed to have a father of his own. But is that all there is out there? If we crystallize all the knowledge that exists out there, going beyond this universe, in terms of time, space and maybe even dimensions, wouldn’t Socrates’ "I only know that I know nothing" still hold? The state sponsored religion (materialism, being that) in the country where I grew up was based on the axiom that matter has always existed, and it precedes mind. What if somehow and somewhere this concept actually works the other way around… You see what I’m sliding into? But is it really necessary, relevant or even possible to answer this question at the moment? If the mind preceded life on the planet, there should be its fingerprints left in the life itself. That’s complex enough for now, as I see it. That’s what Scottie tried to concentrate on.

    • #108552
      scottie
      Participant

      Gavin and Nick 7

      I appreciate both your comments, thanks very much

      I am sorry for being out of the loop for so long but as I explained I have had to deal with family illness
      Anyhow all seems to be well now so, if ( FSM willing) I am not barred again I will study both your posts and try to continue to bore everyone with some more of my observations unless of course you want me to shut up now.

      Nick 7 — all 29 pages read!!! Good grief you are a sucker for punishment. 🙂

      Both your comments are deserving some thought.

    • #108553
      JackBean
      Participant

      scottie, I’m sure you will first answer my very old question, right?

      quote JackBean:

      You have not again said, how did the humans appear on Earth. Try to read this carefully and pick one possibility (or come up with other, but do not start about lysosomes :roll:)
      1) they were created when all the other life on Earth was created few billions of years ago
      2) they were created few tens/hundreds thousands of years ago when the creator was bored again and had no forum to post on
      3) they evolved from lower animals, no matter, whether these were created or arose spontanneously

      you said, that 1 and 3 are wrong, so the creator "arrived" several times on Earth and worked on schifts, right? That would at least explain, why we don’t find fossils of recent animals in say Mesozoic era.

    • #108561
      JackBean
      Participant
      quote scottie:

      Gavin
      You raise a valid point regarding Stephen Gould’s view of Punctuated Equilibrium. There are of course several others with their own hypotheses as to how the process of macro evolution works.

      Carl Woese with his hypothesis of an early era of considerable Horizontal gene transfer.
      Simon Conway Morris with his idea of “front loaded” evolution
      Lynn Margulis — Endosymbiotic theory
      James Shapiro — Natural genetic Engineering
      I could keep on with such leading names as, Allen Orr, Daniel Dennett, PZ Myers, Michael Ruse Coyne etc etc, All tearing lumps out of each other. Their email exchanges can be quite vitriolic at times.
      Freeman Dyson and Richard Dawkins can’t even agree with each other as to what Darwin’s theory actually is.
      These of course are all evolutionary scientists and philosophers.

      So who is right?
      They can’t all be right.

      Right, they are all wrong, all the evolutionists, all IDers and all creators are wrong, but one retired engineer with no biological knowledge is right 😆

      I see, you are using another anti-evo trick. Just saying, that since evolutionists argue against each other, than the evolution is wrong. Hey, they do not argue, whether evolution is true or false, but how exactly it’s occurring. With the same logic, IDers and creators are wrong, because they (with you) are arguing about the exact way, how we were created.

      BTW what do you think about this video?

      I guess it’s fine for you, as an engineer.

    • #108565
      scottie
      Participant

      Jackbean

      The No 2 option of yours is the nearest to my view without of course the rather silly appendage you have attached.

      quote :

      Right, they are all wrong, all the evolutionists, all IDers and all creators are wrong, but one retired engineer with no biological knowledge is right

      My major point seems to have escaped your understanding.

      If evolutionary theory (in all it’s various forms) is correct then there will be no disagreement between the theorists as to what the mechanism that drives macro evolution actually is.
      The reality that different dissenting views not only exist but are actually competing for prominence demonstrates that the mechanism is not known.
      The only common thread that unites the various adherents is that a naturalistic cause is the only one that is acceptable, regardless of where the evidence leads.

      This makes any of these theories philosophically based. That is not a view I have any difficulty with, other than the point that it is regarded as a scientific fact and any dissension from that view is regarded as intolerable and therefore worthy of censorship, as you yourself have so plainly demonstrated.

      The creationists also introduce their religion into their arguments and then present their views as fact.

      And by the way the information I have posted comes from accredited scientific peer reviewed sources. They don’t come from a “retired engineer with no biological knowledge”. This retired engineer is only the messenger, which brings to mind the phrase “Please don’t shoot the messenger” 🙂

      Gavin and Nick 7
      I will respond to your posts asap.

    • #108580
      scottie
      Participant

      Gavin
      Thanks for the very considered and obviously very honest post.
      Your philosophical approach to this matter serves only to re enforce my contention that macro evolutionary theory is essential a philosophical explanation for the origin of species. It is a pity that others who have presented their views, and in many cases so belligerently, cannot appreciate that this naturalistic approach is a philosophical one.
      Origin of species is by nature a historical science, and since none of us were there at it’s inception all evidence must be defined as circumstantial.

      The question therefore is not to do with the evidence itself, but to what origin that evidence is actually pointing.

      My argument is simply that the evidence points away from a naturalistic origin and towards design by an outside agency.

      The proof of concept of this view has been adequately demonstrated by Craig Venter and his team.

      Their minds were directing an intentional design and manufacture. The product being a new species. So I do have verifiable data on my side.

      My contention therefore is not based on a preconceived philosophy, but on pretty solid science.

      The only question that remains is whether the mind(s) involved reside in a physical brain or in some other non-material dimension.
      This would not take such a leap of imagination (or faith) as you perhaps suggest.
      Theoretical physicists have been developing theories around 10 and 11 dimensions for some time now. String and M theory are perhaps the more prominent ones.

      quote :

      Sometimes I think that you just like pulling our chains.

      If I have been, I can assure you it was not intentional, although I accept it may have come over that way. 🙂

    • #108586
      scottie
      Participant

      Nick7
      Very interesting thoughts.

      Let me move forward on your comment

      quote :

      And this thing – who designed the designer? According to my observations, this one is always used as a final Ace up one’s sleeve when the conversation hits the roadblock

      In the past I have deliberately refrained from dealing with this “Ace up ones’s sleeve” other than simply dismissing it as a desperate attempt to gain some credibility.

      However you have understandably given it some credence so I will deal with it.

      The who “designed the designer” argument centers on the concept of spacetime.
      This is the 4th dimension our universe exists in and therefore clearly and logically a designer and creator of this universe must by any reasoning exist outside time and space.
      So questions about who or what came before the designer simply lacks any scientific weight or credibility and stems from a lack of understanding of the nature of the natural world.
      If time along with the other dimensions are products of design, then by simple logic they cannot govern the designer.

      This logic is carried through in General Relativity. It is meaningless to talk about space and time outside the limits of the universe. ( Stephen Hawkins “ A brief History of time Chapter 3)

      Scientifically the question therefore is simply invalid and as I understand it, you have perhaps alluded to this yourself.

      The question of who or what the designer may or may not be is not one that can be answered by science. Additional supporting evidence is required.
      Only some form of evidence based historical documentation can begin to answer this question.

    • #108587
      JackBean
      Participant

      so you have problem to believe in evolution, because you lack evidence for it, but you have no problem to believe in god (and yes, your creator as you described it now, is nothing else than god of any religion), although you have no evidence for its existence?

    • #108588
      Nick7
      Participant

      JackBean, the physical evidence for the creator’s existence is although circumstantial, but it goes beyond the realm of Biology, and it’s substantial enough to be just dismissed (the anthropic coincidences, for instance, and attempts to get out of them with “multiverse” ideas etc..)

      Scottie, thank you for your reply. One point… Stuff like that M-theory "mambo jumbo" led me to conclusion that the line between what we call “naturalistic” and “supernatural” is quite illusive. When a professor of physics seriously talks about possible communication with residents of other dimensions with a help of “gravitons” …. well what is natural and what is supernatural then? Supernatural, the way I see it, might as well be absolutely natural, just sitting on the other end of the abyss of still unknown. A flying piece of aluminum would be considered absolutely supernatural thing many centuries ago simply because a gap between cave level of knowledge and Bernoulli’s principle was too big back then.

    • #108609
      aptitude
      Participant

      scottie,

      The 4th dimension, as described by Einstein, is time, not another space dimension. Also, you can not simply say that "X is possible", physical evidence rather than theoretical derivation is required to say that "X must be true" when dealing with subjects as extraneous as this.

    • #108625
      canalon
      Participant
      quote scottie:

      Let me move forward on your comment

      quote :

      And this thing – who designed the designer? According to my observations, this one is always used as a final Ace up one’s sleeve when the conversation hits the roadblock

      In the past I have deliberately refrained from dealing with this “Ace up ones’s sleeve” other than simply dismissing it as a desperate attempt to gain some credibility.

      Scottie, you have problem understanding why this question is asked to you. It has absolutely nothing to do with Einstein or relativity and everything to do with logic and standard used for you to judge the acceptability of an hypothesis, i.e. to demonstrate a case of double standards.
      You are basically refuting the theory of probability because you deem improbable that self-organisation can lead to complexity. Yet you accept that the probability that something that can create the complexity we are observing (and hence according to your own explanation must be more complex than us, and I would agree with you on that: we sure cannot create artificial life yet, Venter still needed a cell to kickstart his artificial genome) is on the other hand completely within acceptable limits. And I must say that it is not a very credible argument.
      So unless you can give a better explanation on how an improbably complex and undetectable entity is more likely and acceptable than the current theory of evolution, you will just appear as a self deluded man who cannot make a self coherent argument to save the life of his discussion….

    • #108692
      Nick7
      Participant

      Canalon, I think you have a problem understanding that you are asking a gigantic cosmological question, while preferring to stay within the relative safety of the pixel of Darwinian evolution theory (and all its assumptions). Life has not started with evolution; life has started 13.ish billion years ago with a Big Bang (so, apparently, Einstein is as relevant to the issue as Darwin). What we have now is “Boeing 747”; what we had at the beginning was ….. no, not even scraps, but the hydrogen molecules and the “hurricane going through them”. We’re not the result of the order and complexity, which arose by chance alone from the pre-evolution chaos and simplicity, but we are the consequence of the preexisting order and complexity imbedded in the laws of physics and chemistry, which appeared in the very beginning of it all on universal scale.
      Every character in this game takes the rules it’s based on as given, even though, in reality, NOBODY knows the number of possible messy outcomes the Big Bang could’ve produced, which would’ve resulted in different laws of physics, little (or no) number of stars, different (or no) periodic table and NO alive characters present and observing that mess of any kind. What I’m trying to say is that the fact that we’re around, thinking, appreciating harmony and beauty, splitting atoms and writing poetry and it all started with a bunch of hydrogen molecules and the materialized-out-of-the-blue laws of nature is truly amazing (and I believe that every planet with earthlike conditions has the same development going on). No chance alone can be held responsible for it that lightly. You can dance around the roulette table as much as you want, but you will never become a rich man out of it – there is no way to avoid this statistical fact, simply because the preset rules of this “game of chance” favor a casino, not you. Only if you tilt the roulette table (even by 1 mm), the pattern you can bet on will eventually emerge. And as far as biological life goes, that tilt was quite substantial. And again… from the very beginning of our universe.
      To make a long story short…. Without seeing beyond our universe in time and space, how can you objectively conclude that the post-Big Bang rules, thanks to which you exist, are the result of the “s*&t happens” or of the intelligent effort? As a character limited by this event horizon, how can you even objectively quantify which of these 2 causes of it all has a higher probability of happening without applying your pre-event horizon subjective logic to it? Don’t you agree that simplicity first, complexity second is your subjective point of view, not more not less?

    • #108703
      scottie
      Participant

      Sorry I have been away for a few days and only now just catching up.

      I will respond this evening.

    • #108708
      canalon
      Participant
      quote Nick7:

      To make a long story short…. Without seeing beyond our universe in time and space, how can you objectively conclude that the post-Big Bang rules, thanks to which you exist, are the result of the “s*&t happens” or of the intelligent effort? As a character limited by this event horizon, how can you even objectively quantify which of these 2 causes of it all has a higher probability of happening without applying your pre-event horizon subjective logic to it? Don’t you agree that simplicity first, complexity second is your subjective point of view, not more not less?

      Sure but beyond the long words you have to admit that if you want to exclude evolution based on probabilities, you cannot accept an intelligent effort which is similarly improbable. So you have to provide positive evidence of an intelligence beyond life, which for the moment I have failed to see. All we have been presented with are along the line of "evolution is improbable, hence there must be a creator".
      So my problem is not one of inscrutable cosmology, it is one of establishing a single standard of acceptability for a theory that could explain life as we know it. One standard that would be equally applicable to creation and evolution. One standard that requires positive evidence for something, rather than if it is not A, it must be B without any other support for B.

    • #108716
      scottie
      Participant

      Aptitude

      quote :

      The 4th dimension, as described by Einstein, is time, not another space dimension.

      With respect your comment suggests you don’t appear to have a grasp of General Relativity, and how it is different from Newtonian physics. – a common confusion.

      GR provides a framework under which the laws of physics look the same for everyone at every moment, regardless of how they are moving. Einstein, in his theory achieved this by making gravity a property of the universe, rather than of individual bodies, as does Newtonian Physics.

      In other words in GR gravity is not what one body does directly to another, but what a body’s mass does to the surrounding universe

      So General relativity describes gravity as geometry.
      The fabric of the universe is described as the four dimensions of space and time.(spacetime) This fabric which includes time, is full of lumps and bumps that is created by the presence of mass and energy.

      The warping of this fabric is unavoidable whenever anything, be it you, me, a piece of space dust or a planet or even a photon of light tries to travel through the universe in a straight line, it actually follows a trajectory that is curved by any mass and energy in the vicinity. The result of this curvature is what we think of as gravity.

      So when we refer to time, we are referring to a co-ordinate of this fabric, as are the other coordinates of length, breath and thickness. They don’t exist separately.

      That is why any question about time is meaningless if applied to any reality beyond this universe.
      A common misconception is to think of GR in terms of Newtonian physics.

      I don’t wish to sound patronising but I will be happy to explain the difference in Newtonian gravity and GR gravity. The principles in Einstein’s field equations are not too difficult to understand.
      For the sake of clarity I will be happy do it in a separate post.

      quote :

      Also, you can not simply say that “X is possible”, physical evidence rather than theoretical derivation is required to say that “X must be true” when dealing with subjects as extraneous as this.

      My whole argument is centered around the lack of physical evidence for macro evolution. As I understand it, you appear to support “evolutionary theory in whatever form” despite the lack of evidence that I have repeatedly pointed out in all the peer reviewed papers I have referred to.
      So you now appear to be contradicting yourself.

      If one (me) accepts the posit that an external agency designed and created the universe, then spacetime is by logic and theory a product of that design.

      Therefore to posit an argument against this view by asking a question relating to time is, as I have stated, meaningless. Again this is not just my view but that of others much more informed than you or I.

      You will therefore need to find another line of refutation.

      Nick7
      I think we are on the same page. String and M theory are simply speculative theories that eminent scientists who cannot comes to terms with the fact that science does not have an answer to life/universe origins, have to somehow delve into the world of make believe science.

      I refer to these theories to demonstrate the inconsistency of philosophical arguments parading as science. It is noticeable that the science I put forward is not refuted.
      Why not?
      Because it is a philosophy that is being promoted here not science.
      That is why there has been so much heat.
      Question the religion/philosophy of any fundamentalist idea and heat is what you get, as I keep finding out to my cost.

      Evolutionary theory is a philosophy that even Ernst Mayr, one of the foundling fathers of the modern synthesis himself proudly acknowledged.

      Canalon

      When you ask a question that has at it’s root the dimension of time you have moved into the area of science that Einstein and many others have tried to address as legitimate lines of scientific research and theory. Please refer to my post to Aptitude above.

      I understand only too well the demarcation lines between science and philosophy/religion, lines that you are desperately trying to blur.

      The simple question is this.
      Is macro evolutionary theory actually supported by evidence or is it simply your belief that it is.
      Gavin was honest enough to acknowledge his philosophical approach.
      Why are you finding it so hard to do the same?
      After all science is not going to be the loser if you do, will it?

    • #108740
      JackBean
      Participant

      scottie, you are not that much on one page with Nick7, he’s saying, that evolution is not related to the origin of species, while you’re still arguing it is 😉

      The simple question is this.
      Is intelligent design actually supported by evidence or is it simply your belief that it is.

    • #108759
      Nick7
      Participant

      JackBean, I think I was misunderstood a bit. I was not saying that evolution was not relevant to the origin of species. I was saying that any design-vs-randomness discussion about appearance of life will be impaired if it’s focused on Biology / Genetics / Paleontology only. Complex life requires complex and orderly laws of nature as a prerequisite. Appearance of this order and complexity in the universe out of a pea size singularity is as peculiar (and relevant to the discussion) as abiogenesis, for instance. Abiogenesis (as puzzling as it is) requires a rich periodic table, periodic table requires thermonuclear fusion inside the stars (with very unique and rare events of its own, like triple-alpha process), stars formation requires sufficient amount of gravity …..going all the way to the very beginning, which also has a puzzling example of order (the cosmological “flatness problem”). So the way I see it, it’s a legit possibility that the order and complexity observed in our world (biology, physics, cosmology, etc.) may denote intelligence.

      Canalon, thank you for reply! About standard of acceptability (and to complete a thought in the reply to JackBean) … Digging up a prehistoric skeleton and using it to prove a hypothesis is fine, but pre-big-bang cosmological skeletons as well as the reasons behind the laws of nature hidden in the bizarre subquantum world are not immediately available. That’s why I wouldn’t expect Scottie to present a full-scale sufficient hypothesis in a classical understanding of this word at the moment, but I don’t see a problem with occasional sophisticated poking of the current orthodoxy with a stick.

      Scottie, about you getting the heat… I’m sure this section of the forum has seen its share of visitors telling stories about Adam and Eve prancing around together with brontosauruses. So the local old-timers have developed a powerful immune system killing on the spot anything that even moves into any suspicious directions. … I might be wrong, but I think your case is a collateral damage of that immune system. 🙂

    • #108762
      awkko808
      Participant

      Nick7:

      quote :

      What we have now is “Boeing 747”; what we had at the beginning was ….. no, not even scraps, but the hydrogen molecules and the “hurricane going through them”.

      Are you suggesting that complexity has arisen from dust? The problem with this is evolution – not biological evolution, but astronomical evolution – is based on the 13.5-billion year age of the universe suggested by the Big Bang Theory. This extraordinary amount of time is something called deep time and is something I don’t think people can comprehend. You quoted Contact in a previous post saying that we think too much like humans, and deep time is indeed a concept that is almost unthinkable to humans.

      quote :

      So the way I see it, it’s a legit possibility that the order and complexity observed in our world (biology, physics, cosmology, etc.) may denote intelligence.

      The problem with this is that the scientific community has no way to test this. Testability is key to science.

      Sorry if I repeated anything others have said, I kind of jumped into the last few pages.

    • #108778
      Nick7
      Participant

      awkko808 , “dust” was a figure of speech. I’ve suggested that the earthly sequence of events ( nothing->bacteria->Cambrian diversity ), viewed through the glasses of Biology, can psychologically trick one into believe that simplicity first / complexity second is some form of the universal truth. This way of thinking can lead to a belief that even the possibility of a preexistent designer-of-it-all is neither logical nor possible. I’ve suggested that (even putting aside the puzzles of abiogenesis and Cambrian explosion) the evolution itself didn’t start with nothing and is a consequence of the universal laws of nature in all their complexity and order and has to be viewed as a part of the larger picture (not as a standalone event). Therefore, if one is willing to defend the idea that the role of randomness as a “motor starter” for evolution is the only possible explanation, has to be ready to defend the idea that the complexity and order which predated the evolution and allowed the evolution to happen under the right conditions are also the result of some form of random chain of events.
      When Dawkins was presented with this kinda reasoning, he said that the Universe is still waiting for its Darwin (which pretty much means that he acknowledged the reasoning, but had nothing to answer – I don’t blame him though). For example, attempts to attach some form of evolution concept to the just-right post-big-bang density of matter and amount of energy was done, but it was done on a level of ideas tossed into the mix and it’s generally understood that it has to be taken as given and it’s “beyond the domain of science”.
      So… that was my argument…. Design vs randomness ideas do not offer any grounds for quantifying which one is more or less probable or likely. The incline to one of 2 options is of subjective nature.

    • #108782
      scottie
      Participant

      Nick7

      quote :

      Design vs randomness ideas do not offer any grounds for quantifying which one is more or less probable or likely. The incline to one of 2 options is of subjective nature.

      I don’t see this as a subjective option.

      awkko808 is right when he emphasises that testability is key in determining the viability of any hypothesis.

      A hypothesis that is testable is also by nature falsifiable.
      What made Darwin’s hypothesis scientifically valid was his own stated criteria in judging what would falsify it, i.e. the fossil record.

      In his day he relied on what he judged was the incompleteness of the fossil record.
      However today some 150years later that judgement has really gone past it’s sell by date.

      I argue that design does offer grounds for quantifying it as a viable theory.
      An important characteristic of design theory is that it is goal oriented.
      http://books.google.co.uk/books?hl=en&l … esc=y#v=on
      page 7

      I previously set out my thoughts is the post on page 13
      about14351-144.html
      by scottie » Tue Jun 21, 2011 10:20 pm

      quote :

      Lets start with my view.
      We all see functional design in the cell and no one seriously argues with that.
      The question is how did this functional design come about.

      My understanding is that an outside agency is responsible.

      To be regarded as science then it must be falsifiable.
      So once again, is this understanding falsifiable?
      I answer Yes, it can be falsified, and there is nothing “secretive” about this.

      Every one is aware that functional design (whether good, or not so good or even downright bad) displays itself with certain properties.
      1) The function has a purpose. ( i.e. It goes from A to B with C as it’s goal )
      2) Method by which that purpose is achieved. (How does it go from A to B)
      3) It would not contain parts or units that had no function toward the purpose.

      Therefore, falsifying this hypothesis would require that parts of the genome were non functional. Now if that was the case then that would be an argument against my hypothesis.

      So, all you have to do provide evidence that any part(s) of the genome are non functional and my hypothesis is in trouble.

      Six months later and to my surprise no one has come forward with the “Junk DNA” argument that ones like Dawkins and Coyne kept putting out. So it is pleasing to note that, that little piece of nonsense is being ditched.

      So to me this isn’t a balance of probabilities issue.
      There is sound scientific evidence to base judgments on.

    • #108783
      JackBean
      Participant

      1) how exactly does the fossil record falsify the evolution?
      2) junk DNA not, but what about pseudogenes or transposones? These have no function.
      3) I’m looking forward for when the designer will arive again to create new species.

    • #108785
      wbla3335
      Participant

      Blind cave animals with eyes, the appendix and other vestigial structures throughout the tree of life, the tree of life itself, pathogens, inadequate DNA repair, etc., etc., etc. do not speak of a deity due much credit.

    • #108788
      scottie
      Participant

      Jackbean

      quote :

      1) how exactly does the fossil record falsify the evolution?

      Origin of Species Chapter 9
      Darwins words

      quote :

      “Why then is not every geological formation and every stratum full of such intermediate links? Geology assuredly does not reveal any such finely graduated organic chain; and this, perhaps, is the most obvious and gravest objection which can be urged against my theory. The explanation lies, as I believe, in the extreme imperfection of the geological record.”

      (my emphasis)

      I assume you also believe, even after some 150years, in the imperfection of the fossil record as being the reason it does not support Darwin’s views.

      transposones?
      http://users.rcn.com/jkimball.ma.ultran … osons.html
      http://www.sciencedaily.com/releases/20 … 185538.htm

      pseudogenes
      http://www.ncbi.nlm.nih.gov/pubmed/14616058

      quote :

      “….pseudogenes that have been suitably investigated often exhibit functional roles, such as gene expression, gene regulation, generation of genetic (antibody, antigenic, and other) diversity. Pseudogenes are involved in gene conversion or recombination with functional genes……”
      quote :

      3) I’m looking forward for when the designer will arive again to create new species.

      I appreciate Adolescence is a difficult time.

      wbla3335

      quote :

      Blind cave animals with eyes, the appendix and other vestigial structures throughout the tree of life, the tree of life itself, pathogens, inadequate DNA repair, etc., etc., etc. do not speak of a deity due much credit

      Is this a positive argument for Darwinian macro evolution or simply a negative one against design.?
      Could you clarify please.

    • #108789
      JackBean
      Participant
      quote scottie:

      quote :

      3) I’m looking forward for when the designer will arive again to create new species.

      I appreciate Adolescence is a difficult time.

      Really? Didn’t you say that we were created about 40 thousands years ago?

    • #108792
      awkko808
      Participant

      Nick7
      It seems as if you’re proposing that the evolution vs ID debate is insignificant to a debate over how the universe was created. And I’d agree you with you because evolution is a "consequence of the universal laws of nature in all their complexity and order and has to be viewed as a part of the larger picture," and that in the absence of light on how the universe and its laws were established, both ID/creationism AND evolution ARE subjective – even evolution is somewhat faith-based. In the end, however, I am an evolutionist and I do support evolution because it is science-based, and I believe science trumps religion because science is dynamic, while religion is static. In a dynamic reality this only makes sense. But I think this is of a much more philosophical issue.

      scottie
      I am surprised that no one has proposed the junk-DNA argument. Of course there are DNA sequences with regulatory functions, but there is a large number of sequences still with no known function. As wbla3335 also pointed out, the presence of vestigialities (which include noncoding DNA) is BOTH support for macro evolution and evidence against design. As support for macro evolution, vestigialities are accommodated in the theory of evolution through descent with modification from a common ancestor. In such a process, similar structures become inherited but their function may become loss or limited due to the organism inhabiting a new niche. As a negative argument against intelligent design, this implies a wasteful, non-optimal design. If we did have an intelligent designer, why don’t we have eagle eyes, so that our function of ocular acuity is maximized? I’d argue is because over time, humans, as species, have evolved to survive using methods that do not require such high ocular acuity, so it was neither appreciably selected for nor selected against, especially upon the advent of vision-aiding tools.

      When you examine Darwin’s note about the fossil record, you should realize he makes an appeal to science by showing the falsifiability of his theory, something you have agreed about science. Then you should consider the 150 years that has spanned since the writing of Origin. How much improvements have been made to the fossil record? Not just in the number of fossils, but in the way we interpret them. Consider the science of his time versus the science of today.

      As for the fossil record, there are "imperfections," and I will attempt to explain some examples of them. The earliest metazoans (animals) were invertebrates – soft-bodied, mostly boneless animals. It is true that there are many missing links – missing fossils of ‘common ancestors’ – between invertebrate species from which we descended. But there are physical explanations for this: boneless, soft-bodied organisms are much less likely to fossilize as well as bony organisms would. This DOES create blanks in phylogeny, or the evolutionary relationships between species, but when we look at the wide array of support provided from other evolutionary connections, I think one can only fill in the blanks at that point. Thus, when these imperfections in the fossil record existing as blanks are filled in as interpolations, you could argue that they don’t support it, but it doesn’t falsify it, because evolution based on strong evidence from other evolutionary relationships provide the relation to be able to fill in those blanks. You’d have to falsify evolution that is strongly supported in the more recent episode of life.

      As for considering the science of his time, you can’t read Origin and believe that only the ideas of that book will apply 150 years later, because then you’d be excluding the genetic, biochemical/molecular, microbiological, and much more other sources of evidence that support evolution.

    • #108797
      scottie
      Participant

      awkko808

      Thanks for your input.
      You have made a few interesting points.
      I note in your comment to Nick7 that you recognise that

      quote :

      even evolution is somewhat faith-based.

      Faith (belief) could rightly be classed as subjective and I have due respect for any faith.

      It’s the science bit that I question.

      You deal with issues that wbla3335 cited so I will take your responses as from him.

      quote :

      the presence of vestigialities (which include noncoding DNA) is BOTH support for macro evolution and evidence against design. As support for macro evolution, vestigialities are accommodated in the theory of evolution through descent with modification from a common ancestor. In such a process, similar structures become inherited but their function may become loss or limited due to the organism inhabiting a new niche.

      Firstly
      This argument applies as much to design by an outside agent as to neo Darwinian theory.
      How a function came about has nothing to do with how a loss of that function occurred.

      Functional loss is about information corruption
      The discussion is about how function arrived not how it was lost.

      Secondly.

      quote :

      As a negative argument against intelligent design, this implies a wasteful, non-optimal design. If we did have an intelligent designer, why don’t we have eagle eyes, so that our function of ocular acuity is maximized?

      This argument about non optimal design is with respect a red herring. You yourself have perhaps unwittingly acknowledged this in your further comment.

      A designer will design something that will function optimally in an environment for which it is designed.

      You wouldn’t argue that a turbo charged Formula 1 car designed for the race track is any more or less optimally designed that your average family neighbourhood shopping vehicle would you.

      You will have perhaps noticed that I don’t preface the word design with the Intelligent adjective simply because intelligence is very subjective when used as an adjective as you yourself have demonstrated.

      Please don’t misunderstand me I am not relying on mere semantics to buttress my argument. I am simply making the point that definitions in science are very important.
      Design could be good, bad or ugly. Being ugly is not an argument against design.
      My own personal appearance can testify to that. 🙂

      However coming back to the vestigial point.
      This has more of a problem for Darwinian Natural selection theory than you perhaps appreciate.

      Professor David Dreamer of Ohio State Universityhas investigated this subject and you can find his paper entitles ENTROPY AND CAVE ANIMALS here
      https://kb.osu.edu/dspace/bitstream/han … sequence=1
      This is how he commences his paper (just to whet your appetite)

      quote :

      It is generally accepted that these animals are descendants of eyed and pigmented ancestors. Since this trait is so widespread among cave animals, any explanation of its evolutionary mechanism must also account for its ubiquitous occurrence. A number of hypotheses have been offered but it remains something of a problem for Darwinian theory

      He concludes with a proposal that has to move away from Darwinian natural selection to make a reasonable case, that interestingly can be applied to the design view as well.

      wbla3335 reference to the appendix as a vestigial structure is simply becoming another one of these urban myths.
      http://www.scientificamerican.com/artic … ction-of-t

      I will deal with this Junk DNA issue separately because there are many points of interest that I do feel is deserving of a separate post.
      Additionally your comments on the fossil record are also worthy of a separate post.

      Jackbean

      quote :

      Didn’t you say that we were created about 40 thousands years ago?

      Exactly where will you find that little piece of missinformation.
      Manufacturing quotes attributed to me adds nothing to a sensible discussion.

    • #108798
      wbla3335
      Participant

      scottie

      Every opinion under the sun can be found on any topic imaginable. They cannot all be true. Providing links to opinions that support your position does nothing to strengthen your position. We know you’re not the only person who doesn’t want to believe in evolution. I find that what is common to those who do not believe in evolution is not the failure to be convinced by the evidence (most don’t bother to look at the evidence – you do, and I commend you for that) but an aversion to wanting to believe in evolution. Aversion to snakes has a biological origin. Aversion to ideas is psychological.

    • #108807
      scottie
      Participant

      wbla3335

      quote :

      Providing links to opinions that support your position does nothing to strengthen your position

      I would argue that providing evidence from Scientific journals and peer reviewed scientific papers strengthens my position. The fact that you don’t regard this as recognisable support I find rather surprising.

      quote :

      Aversion to snakes has a biological origin.

      This Is simply your opinion isn’t it?
      btw
      I am a bit tied up for time so I will respond on the fossil record and junk DNA later.

    • #108808
      awkko808
      Participant

      scottie,
      I think I understand your argument much more clearly now and I can see why you’ve been involved in this thread for quite a few pages. Your position on a designer of life (and perhaps the universe?) is hard to tackle because there is in fact no evidence against a designer. The complexity of the designer theory arises from the fact that any evidence for evolution and natural selection can be claimed for a designer, and evolution and natural selection themselves can be a mechanism through which a designer may operate. Going back to what Nick7 said, you’d have to dissect the laws by which the universe operates to perhaps see how the designer operates. Then we’d be able to discuss possible evidence for/against a designer. To argue over whether a designer exists or not is outside the realm of science. I think you do understand that because you are, for the most part, presenting problems with evidence for Darwinian natural selection and I acknowledge that.

      quote :

      Functional loss is about information corruption
      The discussion is about how function arrived not how it was lost.

      Functional loss AND arrival could be due to design. Functional loss and arrival could ALSO be due to natural selection, however.

      quote :

      You wouldn’t argue that a turbo charged Formula 1 car designed for the race track is any more or less optimally designed that your average family neighbourhood shopping vehicle would you.

      My initial argument was against that of intelligent design. I wouldn’t argue that a race car is any more designed than a shopping vehicle. Obviously both were designed.

      Regarding my earlier comment about design, it would be a red herring depending on your perspective. I had argued against an intelligent designer, but you viewed it from a designer perspective, and in light of that my comment would in fact be fallacious. In conclusion, there seemed to be a very bad misunderstanding of your argument on my part.

      It seems clear that to propose a designer would be logically correct. But science encompasses logic and empirical evidence, the latter of which I do not currently know of existing for a designer. It seems, with respect, insignificant to argue over whether a designer exists, at least with current human knowledge of the physical world.

    • #108809
      wbla3335
      Participant
      quote scottie:

      I would argue that providing evidence from Scientific journals and peer reviewed scientific papers strengthens my position. The fact that you don’t regard this as recognisable support I find rather surprising.

      If the proportion of the "evidence from Scientific journals and peer reviewed scientific papers" that supports your position were more than tiny, your position might be a bit stronger.
      As I said earlier,

      quote wbla3335:

      Every opinion under the sun can be found on any topic imaginable.

      And some of it gets published. Publication guarantees nothing.

    • #108810
      JackBean
      Participant

      So far, although you were bullshitting with non-sense, I have respected you at least because you were stick with your opinion, no matter, how silly it may be. But I see, you are neglegting yourself already.

      about14351-336.html

      quote JackBean:

      scottie, I’m sure you will first answer my very old question, right?

      quote JackBean:

      You have not again said, how did the humans appear on Earth. Try to read this carefully and pick one possibility (or come up with other, but do not start about lysosomes :roll:)
      1) they were created when all the other life on Earth was created few billions of years ago
      2) they were created few tens/hundreds thousands of years ago when the creator was bored again and had no forum to post on
      3) they evolved from lower animals, no matter, whether these were created or arose spontanneously

      you said, that 1 and 3 are wrong, so the creator “arrived” several times on Earth and worked on schifts, right? That would at least explain, why we don’t find fossils of recent animals in say Mesozoic era.

      quote scottie:

      Jackbean

      The No 2 option of yours is the nearest to my view without of course the rather silly appendage you have attached.

      Another thing you have not responded to:

      quote JackBean:

      The simple question is this.
      Is intelligent design actually supported by evidence or is it simply your belief that it is.

      Since you require evidence for evolution, how is that, that you do not require one for ID?

      quote scottie:

      quote :

      Right, they are all wrong, all the evolutionists, all IDers and all creators are wrong, but one retired engineer with no biological knowledge is right

      My major point seems to have escaped your understanding.

      If evolutionary theory (in all it’s various forms) is correct then there will be no disagreement between the theorists as to what the mechanism that drives macro evolution actually is.
      The reality that different dissenting views not only exist but are actually competing for prominence demonstrates that the mechanism is not known.
      The only common thread that unites the various adherents is that a naturalistic cause is the only one that is acceptable, regardless of where the evidence leads.

      This makes any of these theories philosophically based. That is not a view I have any difficulty with, other than the point that it is regarded as a scientific fact and any dissension from that view is regarded as intolerable and therefore worthy of censorship, as you yourself have so plainly demonstrated.

      Imagine, that we are able to travel in time and transfer say a car into medieval times. They will try to explain, how the car functions, but none of them will be probably right, since they don’t have enough knowledge. Does that mean that the car doesn’t work?

    • #108816
      scottie
      Participant

      Jackbean is on one of his rants again so I will just patiently wait for him to calm down

      awkko808

      It is such a pleasant change to discuss this matter in a rational way and for that I do sincerely thank you.
      Actually I agree with just about everything you have said,only to comment on your last sentence.

      quote :

      It seems, with respect, insignificant to argue over whether a designer exists, at least with current human knowledge of the physical world.

      You are right in what I have been trying to do, that is to point to the empirical evidence that shows how unsupported Darwinian theory is.

      I fully realise that this attacks the very core belief of many, hence the philosophical noise that is generated toward me.

      You so rightly say that science encompasses both logic and empirical evidence.
      What I have been doing is presenting empirical evidence against the Darwinian mechanism of speciation, not the logic of it.

      Logically a designer could quite rationally have set in train the Darwinian mechanism.

      The problem is —- Does the empirical evidence point in that direction?

      Lenny Moss puts this far better than I can

      quote :

      Once upon a time it was believed that something called “genes” were integral units, that each specified a piece of a phenotype [that is, a trait], that the phenotype as a whole was the result of the sum of these units, and that evolutionary change was the result of new genes created by random mutation and differential survival. (Moss 2003, p. 185)

      Question—Has that belief been supported by the empirical evidence.

      The comparative genome analysis of the Human Genome project has produced some unexpected results.

      Lets take just one strand of evidence from the picture that has emerged

      Non coding (so called Junk) DNA accounts for only 10% of a one celled prokarote,
      only 32% in yeast,
      75% in roundworms,
      83% in insects,
      91% in a pufferfish.
      Costa, Fabricio F. (2008). "Non-coding RNAs, Epigenetics and Complexity", Gene vol. 410, pp. 9-17.

      Most of the human DNA (some 98%) does not code for proteins.
      The bulk of this non coding DNA was referred to as junk i.e. the evolutionary accumulation of meaningless genetic leftovers.
      This was a central argument from the likes of Dawkins, Coyne and others and cited as as a main line evidence of random Darwinian evolution.

      However it now appears that the more complex the organism the greater is the amount of this “junk”.
      This is highlighted in this paper
      The relationship between non-protein-coding DNA and eukaryotic complexity
      http://onlinelibrary.wiley.com/doi/10.1 … 4/abstract

      quote :

      We show by analysis of sequenced genomes that the relative amount of non-protein-coding sequence increases consistently with complexity. We also show that the distribution of introns in complex organisms is non-random.

      The above is a direct quote from the above abstract and this evidence is the direct opposite of what was believed to be true, based on Darwinian theory.

      Notice also that these intron distributions are non random.
      Now this is some the evidence from the non protein coding part of the genome.

      What about the other book end— the protein coding part.

      quote :

      Once upon a time it would have stood to reason that the complexity of an organism would be proportional to the number of its unique genetic units. (Moss 2003, p. 185)

      Well it was first expected that the Human genome would contain about 100,000 genes.
      Now why would a figure around 100,000 be expected?
      Simply because a tiny roundworm has about 20,000 and humans are clearly much more complicated, therefore the, one gene one trait, concept that our good friend Mr Dawkins contended, had to predict much more than in a simple roundworm.

      This project has revealed our genome to contain only about 23,000
      But that is not all.
      Recently researchers have found that a pea aphid has about 34,600 genes and better still, that the water flea has 39,000 genes.

      How does Darwinian theory explain this?
      Well it can’t because the evidence requires a completely different principle of causation.

      The only other causation I am aware of is design by some outside agency.
      ( Craig Venter has demonstrated the principle of that concept.)

      If there can be another cause that explains this evidence then it should be explained rather than clinging to a causation that clearly isn’t supported by the empirical evidence.

      You have quite rightly pointed to areas of evidence that can be examined and all I have done is examine some of that evidence (there is a lot more) and report on it.

      Who or what the designer may or may not be is a question that science cannot answer at this point, because that cause appears to sit outside our physical laws.
      Defining or trying to understand that cause is a philosophical/religious question that the physical sciences cannot engage with except that scientists have the humility to acknowledge that, as indeed many do.
      Sorry for such a long post.

    • #108817
      wbla3335
      Participant

      scottie

      I believe you have somewhere accused scientists of neglecting supernatural influences. Well, you are right. Scientists must do this. Science would have no power if they didn’t.

      http://weber.ucsd.edu/~aronatas/project … e.3.12.htm

      Concluding the existence of a supernatural cause of anything by an analysis of the evidence amassed by the sciences is untenable. What is tenable is the desire to justify a preconception by selective interpretation. Your strategy is the same as that used by creationists: ignore or discount the majority of human knowledge and try to hammer the remaining minority into the square hole of what you want to be true. I have no problem for you to believe whatever you want (since you don’t seem like the type who wishes harm to those who don’t share your views), but you are unlikely to win any converts on this particular forum.

      You almost sound like someone in transition – raised Christian, intelligent enough to see the absurdity of a theist god who helps certain teams win football games, but sufficiently indoctrinated against the purposelessness of a natural universe. May you continue your journey. As someone said earlier, we all take leaps in choosing what we believe. Some leaps involve probabilistic extrapolation from the known, some involve faith. Scientists, by their nature, choose the former. Theists and deists, by their nature or parents (usually the parents), choose the latter.

      I hope to see you on the "other side" some day.

    • #108818
      JackBean
      Participant

      scottie, I think you want to answer before I "calm down"

    • #108823
      canalon
      Participant

      Scottie

      Would you please answer on your position on double standard when it comes to proof?

      quote :

      Professor David Dreamer of Ohio State University has investigated this subject and you can find his paper entitles ENTROPY AND CAVE ANIMALS here
      https://kb.osu.edu/dspace/bitstream/handle/1811/5008/V64N03_221.pdf?sequence=1
      This is how he commences his paper (just to whet your appetite)

      quote :

      It is generally accepted that these animals are descendants of eyed and pigmented ancestors. Since this trait is so widespread among cave animals, any explanation of its evolutionary mechanism must also account for its ubiquitous occurrence. A number of hypotheses have been offered but it remains something of a problem for Darwinian theory

      He concludes with a proposal that has to move away from Darwinian natural selection to make a reasonable case, that interestingly can be applied to the design view as well.

      You have noted that this paper is dated from 1964, and that since then our understanding on how evolution works has slightly changed. Even if the Darwinian idea is still at the core of the theory of evolution, there are plenty of things that have been better understood and explained with respect to mechanisms and the implication of genetics. This paper has become largely irrelevant because it simply ignores what molecular biology has discovered since it was published. I do not blame the author for that, but using it as a support for your own theory only demonstrate your total and utter lack of understanding of the subject at hand 🙄

    • #108825
      awkko808
      Participant

      scottie,
      Thank you, rationality is the only way to solve these debates. It is a hot topic but I see no reason in losing rationality over this debate. In fact, I do believe there is good possibility for your beliefs to be true based on the number of sources from which you have drawn support for your argument. I actually took some time to read over Deamer’s article because upon skimming it did pose some challenging points. Upon further reading however I could see I wasn’t convinced. Although I am no expert in animals, especially cave animals, I don’t agree with it much because of several specific problems:

      First of all, one of Deamer’s underlying premises seems to be that natural selection is goal-directional, through which life should move from simple to complex. I believe this is an error, as natural selection implies that any organism, simple or complex, able to survive in an environment has a better probability of generating offspring with its genes. Technically, degenerate evolution would be very possible through natural selection, but this doesn’t happen very often because the loss of sensory organs suggested by Deamer would usually be detrimental in nature. What Deamer hypothesized was that degenerate evolution would be possible in a lab environment, and I believe it would be possible. But of course that wouldn’t be NATURAL selection now would it?

      From Deamer’s article:

      quote :

      It is generally accepted that these animals are descendants of eyed and pigmented ancestors. Since this trait is so widespread among cave animals, any explanation of its evolutionary mechanism must also account for its ubiquitous occurrence. A number of hypotheses have been offered but it remains something of a problem for Darwinian theory.

      I believe what you are arguing is that multiple analogous adaptations pose a problem for Darwinian theory. As I mentioned above, natural selection has no bias with respect to degeneracy. If it works, it works. I believe that over long periods of time, which is what Darwinian theory is partly based on, it would be possible to see such analogous adaptations. This is where I believe faith comes into play, because I have absolutely no idea what could realistically happen over such long periods of time, or "deep time" as some would call it. Perhaps the real argument against Darwinian theory should be on whether such changes can occur over vast periods of time.

      quote :

      To carry the argument further, if very small decreases in energy expenditure did have positive survival value in caves, it would seem likely that evolutionary processes would produce cave animals which are miniaturized versions of corresponding species aboveground. However, in my experience the size ranges are not drastically different.

      Another problem is in this argument. Deamer rebuts Rhoades’s suggestion that, given a cave environment, eyes would be lost in cave-dwelling organisms because of the minute energy costs required to maintain eyes. Deamer goes on even to say that if energy expenditure was a problem for cave-dwelling animals, then they would eventually shrink. This is erroneous because for cave-dwelling animals to "shrink" they would have to lose some adaptations, and this would be disadvantageous to their survival. This is from what I’d speculate, however, because I am no expert in cave animals.

      quote :

      There were no selective processes going on to preserve strains with vision and pigment. Therefore, randomization of the genetic information could occur through mutation without destroying the survival potential of the species and naturally the system would proceed to the maximum entropy possible. This would result in totally eyeless and unpigmented species of animals.

      What he did here was compare a process that probably occurred in cave animals to a process that probably occurred in the rest of the animal kingdom. As I mentioned above, degenerate evolution could very well be possible through natural selection but it doesn’t happen in nature.

      The point, I guess, is that Deamer is taking a few bits of Darwinian theory and trying to explain it in a lab environment. But Darwin’s mechanism of natural selection, as its name might imply, takes place in nature.

      scottie:

      quote :

      Well it was first expected that the Human genome would contain about 100,000 genes.
      Now why would a figure around 100,000 be expected?
      Simply because a tiny roundworm has about 20,000 and humans are clearly much more complicated, therefore the, one gene one trait, concept that our good friend Mr Dawkins contended, had to predict much more than in a simple roundworm.

      This project has revealed our genome to contain only about 23,000
      But that is not all.
      Recently researchers have found that a pea aphid has about 34,600 genes and better still, that the water flea has 39,000 genes.

      How does Darwinian theory explain this?

      The relation you hold here is that an increase in the NUMBER of genes is an increase in the complexity of an organism. I’d argue that the number doesn’t attribute completely to the complexity of the animal. More important factors, aside from the amount of genes, is how the organism expresses it, and WHEN it expresses the genes. To be more specific, there are certain developmental genes I have heard of that are expressed at distinct stages of the organism’s development and SMALL changes in the genes can lead to LARGE changes in the organism’s morphology. Although I’m sure there are more that exist, the only genes I have been taught about are the Hox genes, commonly studied for their effects on segmentation in Drosophilia.

      You’d also ask how the increase in noncoding DNA ties in with this. Well, since a good number of noncoding DNA sequences have been known to REGULATE DNA and thus gene expression, we can speculate that the increase in noncoding DNA may correlate to an increase in regulation mechanisms in humans that allow certain genes to be expressed at precise times allowing for particular physiological functions to happen. Thus, it seems plausible that not only do the number of genes factor into the complexity of an organism, but also the manner (i.e. how much they are expressed) in which they are expressed and when they are expressed. Just because humans have less coding genes doesn’t mean they’re less complex.

      I also apologize for the long post. The larger the post, the more likelihood of error it seems.

    • #108827
      Dov Henis
      Participant

      EarthLife Genesis@Aromaticity.H-Bonding

      A.
      Purines and pyrimidines are two of the building blocks of nucleic acids. Only two purines and three pyrimidines occur widely in nucleic acids.

      B.
      Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring.

      A purine is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Purines, including substituted purines and their tautomers, are the most widely distributed kind of nitrogen-containing heterocycle in nature.

      Aromaticity ( Kekule, Loschmidt, Thiele) is essential also for the Krebs Cycle, for energy production.

      (Wikipedia)

      C.
      Natural selection is E (energy) temporarily constrained in an m (mass) format.

      Natural selection is a universal ubiquitous trait of ALL mass spin formats, inanimate and animate.
      Life began/evolved on Earth with the natural selection of inanimate RNA, then of some RNA nucleotides, then arriving at the ultimate mode of natural selection – self replication of RNAs. ALL Earth life is evolved RNAs. The drive and purpose of EarthLife is to enhance RNAs replication, its natural selection.

      Aromaticity enables good constraining of energy and good propensity to hydrogen bonding. The address of EarthLife Genesis, of phasing from inanimate to animate natural selection, is Aromaticity. Hydrogen Bonding.

      Dov Henis (comments from 22nd century)
      http://universe-life.com/

    • #108830
      scottie
      Participant

      wbla3335
      scottie

      quote :

      I believe you have somewhere accused scientists of neglecting supernatural influences.

      You will not find that I have anywhere, said that nor have I made any such accusation. I appreciate you used the word “believe” which only goes to show that beliefs can be wrong. 🙂

      What I have said, and here I paraphrase the summation of all my posts

      Scientists should not stray into matters that involve the unnatural or supernatural. Scientists must try and explain matters within the known physical laws.
      Explanations beyond physical laws are philosophical.

      When the evidence does not support a physical hypothesis then that should be recognised and acknowledged.

      Now I do not know of any physical process that can explain the origin of life except that life has only been known to originate from another pre existing life.
      That is what science does testify to.

      I also do not know of any physical process that can change one species into another quite different species. (definition of species can of course be quite arbitrary.) let’s use this forums definition.
      http://www.biology-online.org/dictionary/Species

      I do know that within existing species, variation can and does occur and depend on genetic environmental and dietary factors.

      I know of only one example where known physical processes have been used to produce a new species. That is the case where an outside agent has, albeit crudely, designed and changed one life form into another. I of course refer to the Craig Venter team.
      No doubt others will follow. They have not created a new life, but simply changed and existing life form into another.

      As I understand it the smallest unit of a species is a single cell as is also the smallest unit of a life.
      I therefore maintain that any attempts to understand how life arose also by definition would understand how species arose.

      I am not aware of any physical process that can or has caused a prokaryote to change into a eukaryote.

      Finally I do not know of any physical process that can attach symbolic meaning to any chemical molecules that exist in the various genetic codes that life processes utilise.

      I think that pretty well sums up my understanding of where science is at this time on this subject.

      Since you started off your psychological analysis of me with an incorrect belief, would you mind terribly if I reserve my judgement on it. 🙂

    • #108831
      scottie
      Participant

      canalon
      Cave animals

      quote :

      You have noted that this paper is dated from 1964, and that since then our understanding on how evolution works has slightly changed. Even if the Darwinian idea is still at the core of the theory of evolution, there are plenty of things that have been better understood and explained with respect to mechanisms and the implication of genetics. This paper has become largely irrelevant because it simply ignores what molecular biology has discovered since it was published. I do not blame the author for that, but using it as a support for your own theory only demonstrate your total and utter lack of understanding of the subject at hand

      Patrick oh Patrick, you offer such kind words of encouragement, what can I say? 🙂 How about starting here

      Yes the paper is from 1964.
      1) Has it been refuted? If so please provide me with a source.
      2) Simply stating that our understanding of evolution has slightly changed is just a statement. Could you please explain in what way has it changed to make this paper irrelevant?
      3) You don’t blame the author for that but you blame me. That is a delightful little bit of “shoot the messenger” rhetoric.:)
      4) The argument though is that vestigial organs militate against functional design. If they are vestigial then they must have had a use initially, therefore this is an argument for degeneration or atrophy, not one against design. It seems you don’t fully understand the nature of this argument.
      5) According to Darwinian theory Natural selection is the force, that selects for survival from existing functions. Random mutations are the creative force in Darwinian theory. Since these organs are not necessary for survival Natural selection is not the driving mechanism for their loss. That driving mechanism is a function of increasing entropy and is not a Darwinian mechanism. That is the point Professor Deamer is making.
      6) Rhoades (1962) legitimately argues that since less energy is required this make for better survival, hence Natural selection is the force.
      7) Deamer counters his argument that this should mean that the cave animals are smaller than the corresponding above ground species, but in his experience there is no appreciable difference in size. He then goes on to cite Vandel (1961) that shows in the case of the blind salamander, in the laval stage, eyes are there and then disappear with maturity. Hope that helps you better understand the principles of Deamer’s paper.
      8) btw I have emailed the professor and hopefully will get a response. I will keep you informed, so we can all update our understanding.

    • #108832
      scottie
      Participant

      awkko808

      May I refer you to my response to Patrick where I explained my understanding of his paper.

      I fully note your comments however can we put this in abeyance until I perhaps get a reply from Professor Deemer

      So to your response

      quote :

      The relation you hold here is that an increase in the NUMBER of genes is an increase in the complexity of an organism. I’d argue that the number doesn’t attribute completely to the complexity of the animal. More important factors, aside from the amount of genes, is how the organism expresses it, and WHEN it expresses the genes.

      Sorry I should have been a bit clearer, I was not expressing my view, I was expressing the view of the researchers. Perhaps if I cited a reference it would have been clearer.
      http://www.ornl.gov/sci/techresources/H … mber.shtml

      The rest of your paragraph I totally agree with.

      The point I was making was that evolutionary theory was positing that the increase in complexity was a random happening of the mutation of existing genes, and thereby complexity of phenotype was a result of a greater variety of mutated genes.
      We now know that is not the case.

      We also now need to ask the additional question.

      Since random mutation is the creative force, with natural selection being the selective force
      How does this creative force change, not only the function of the genome, but also how the individual genes are expressed, and again when they are expressed?
      And even more than that how is the ever changing growth trajectory of the embryo is managed by this random process.

      Natural selection has nothing to do with this process. It only comes into play when the environment can act to select one of these changes once they have taken place, to an advantage.

      And of course the more complex the organism the more complex these coordinated series of changes have to be.

      Now everyone is just making the assumption that this can happen, but the improbability (now I don’t wish to go into the theory of probability) of this is so great that even the theory itself recognises it.
      Why else is common decent the other fundamental pillar.
      Because it only happened once, says the theory.

      It is this creative force that I keep challenging.
      Science advances in a culture of doubt.

      Your second paragraph I agree with.
      The more of this so called junk the more regulated is the organism.
      But this junk DNA was being (and indeed in some quarters) still being offered up as the refuse of evolutionary processes and was and indeed still is put out as an argument against design.

      Now there is more to this junk question but may I leave that to another post.
      RSS is now overcoming me. 🙂

    • #108835
      EnricoPallazzo
      Participant

      Hello,
      I stumbled over this vivid discussion and cannot resist to interfere…

      quote scottie:

      [
      Yes the paper is from 1964.
      1) Has it been refuted? If so please provide me with a source.
      2) Simply stating that our understanding of evolution has slightly changed is just a statement. Could you please explain in what way has it changed to make this paper irrelevant?

      I think you do not understand the basic concept of schience at all. Wikipedia.com puts it into a nice phrase: "Science (from Latin scientia, meaning "knowledge") is a systematic enterprise that builds and organizes knowledge in the form of testable explanations and predictions about the universe." Its all about progression! Scientific data are constantly generated, expanded, revised and sometimes dismissed or refuted. You simply cannot take a single paper, especially an old one, for absolutely granted and ignore all the scientific knowlegde that has been generated since then (what a christian attitude!). That doesn`t make old papers "irrelevant", but in the light of new discoveries quite often much more reasonable explanations can be given for many phenomena. In fact, thats what canalon already tried to explain to you. If you really want to learn about a topic, read recent literature (e.g. reviews).

    • #108845
      wbla3335
      Participant
      quote scottie:

      You will not find that I have anywhere, said that nor have I made any such accusation. I appreciate you used the word “believe” which only goes to show that beliefs can be wrong. 🙂

      I’m too lazy to plough through your posts to find where I was led to my belief. Either I am mistaken, or you have not taken enough care in expressing yourself. The rest of my last post, however, remains as it is.

    • #108846
      Nick7
      Participant

      Let me briefly summarize my subjective perception of the situation here. Unless I am biased, the biggest counter argument to Scottie’s claims about improbability of the randomness’ role in the processes described over the last 32 pages is absence of any evidence that supports existence of the supernatural “intelligent agency” that Scottie keeps referring to. Am I correct?

    • #108848
      scottie
      Participant

      EnricoPallazzo

      Thanks for your interjection, it’s nice to have a fresh view presented.

      Firstly could we nail down this point.
      The introduction of vestigial organs is an argument for degeneration in an already existing function, whatever the cause of that degeneration.
      It does not stand up as an argument against functional design.

      However canalon and now you both make the same point about essentially keeping up with new information as this is the way science proceeds. You also say that old information isn’t necessarily outdated or wrong. I completely agree.
      However simply reading reviews does not advance your knowledge of a subject. Reading the papers themselves is what matters and that is what I encourage you to do.

      So let examine what the latest papers are revealing about evidence on this subject.
      Of necessity this post will be somewhat long, because in science the detail of evidence is important.

      It is still not known how cave fish have lost eyesight and pigmentation. This is not just my view.

      W. R. Jeffery (2005) Adaptive Evolution of Eye Degeneration in the Mexican Blind Cavefish put it this way.
      http://jhered.oxfordjournals.org/content/96/3/185.full

      quote :

      Today, the mystery still persists, although the field of possibilities has been narrowed to two opposing hypotheses… The neutral mutation hypothesis (Kimura and Ohta 1971) suggests that eye regression is caused by random mutations in eye-forming genes, which accumulate in cave animals under relaxed selective pressure

      Remember this is the hypothesis that Professor Deamer offered in1964.
      Jeffery continues.

      quote :

      In contrast, the adaptation hypothesis suggests that loss of eyes is adaptive and has a selective advantage in the cave environment (Culver 1982; Poulson 1963;Poulson and White 1969). As implied in the Darwin quote, however, the actual benefits of blindness have been difficult to understand.

      This hypothesis is the one favoured by Jeffrery along with others, and is a Darwinian explanation.

      Jeffery summarises the very interesting discoveries in the molecular changes that take place during this process. (new information) The paper is a fascinating read.

      Eye formation does commence in the embryo but is arrested at a certain stage in development. ( Deamer in 1964 referred to Vandel’s (1961) discovery of this fact.)

      This arresting takes place during lens formation.
      However no genes understood to function during eye formation, appear to be damaged.
      Also when the lens of an embryo of a surface fish is transplanted into the embryo of a cave fish at the same stage development the eye in the cave fish continues to develop normally. When a reverse transplant takes place the eye of the surface embryo is arrested, suggesting that the lens is the central controller of eye formation.

      It has also been discovered that many genes are up regulated in cavefish relative to surface fish, rather than vice versa. The expanded regulation in particular of the hh genes seems to be quite central in the degenerative process.
      It is for these reasons that Jeffery hypothesises that Natural selection is at work and not mutation.

      In his 2008 paper Jeffery rows back a little in his assessment especially in the case of loss of pigmentation.
      http://www.life.umd.edu/labs/jeffery/Pu … o.2008.PDF
      cavefish and microevolution of development

      quote :

      Surface fish and cavefish brains are remarkably different, much more than expected from phenotypic variation within the same species. Page 270 2nd column
      …The evolutionary forces that generate these changes are not understood. …page 271 1st column
      How and why behavioral changes have evolved is almost completely uncharted territory.
      The relative simplicity of cavefish behaviors may reflect the short time since their original divergence, underscoring the importance of a micro evolutionary perspective. Astyanax has the potential to make significant contributions to understanding the evolution of behavior at the molecular level.

      Now
      H Wilkens University of Hamburg, Germany has a view that favours the mutation or neutral theory. (introduced by Deamer in 1964) in his 2010 paper
      Genes, modules and the evolution of cave fish
      http://amec.glp.net/c/document_library/ … -21261.pdf
      This is what he says.

      quote :

      Therefore, it is likely that in cave fish with a transplanted lens from surface fish the retina remained in its reduced state characteristic of other cave fish. This result is supported by the observation that these specimens did not respond to light (Romero et al., 2003). This finding suggests that for the restoration of an eye two subunits, lens and retina, would be necessary. Thus the ‘complete restoration of the eye’ as hypothesised by Jeffery (2005) has not been shown and hence there is no support for the hypothesis that the lens alone has a ‘central role in cave fish eye development’.

      Thus, I suggest that eye regression in Astyanax seems to be mainly because of down regulation of structural genes by the expanded hh gene expression,
      which was suggested to have a causal role in eye development of the cave fish (Yamamoto et al., 2004).
      However, the question of what causes downregulation of hh genes remains unsolved.

      Keeping in mind that expanded expression of the hh genes may have a causal role in eye reduction of the parental cave fish, the development of ‘back to surface eyes’ could be explained by the secondary restriction of expression and downregulation of hh genes. I suggest that this could be due to as yet unidentified genes. In contrast to the hh genes, it is likely that these genes show loss-of-function mutations. In ‘back to surface eyes’ they could be expressed again because of the complementary restitution of their function.

      I suggest that the variability of regressive traits is attributed to the loss of selection. Explanations of the reduction of biologically functionless traits in cave fish based on selection seem to be less probable because natural selection usually acts strongly to eliminate phenotypic variability. Therefore, variability of regressive traits in cave animals would be one of the rare cases, in which random mutations can manifest and are not eliminated by natural selection acting to preserve the functional capability of a module.

      Incidentally the paper of (Romer 2003) Wilkens refers to is here
      http://www.ncbi.nlm.nih.gov/pubmed/14984036
      Romero A, Green SM, Romero A, Lelonek MM, Stropnicky KC. 2003
      One eye but no vision: cave fish with induced eyes do not respond to light.

      quote :

      Both the eyeless epigean fish and cave fish with induced eyes are indifferent to the illumination whereas the surface forms are scotophilic, suggesting that optic development and phototactic behavior are decoupled.

      So despite the passing of nearly 50 years Professor Deamer’s hypothesis is still very much in alive and kicking.

      The last point I make is this.
      Jefferies (2008) makes good mention of cave fish as being a natural lab for the study of evolution since here we have both ancestor (suface) fish and their descendents (cave fish)
      Also note that he recognises this process as micro evolution (variation within a species)

      Now lets return to Deamer’s reference to (Woods1956) the evidence from which can be downloaded here.
      http://libsysdigi.library.uiuc.edu/OCA/Books2008 08/bulletin1/bulletin25chic/bulletin25chic.pdf
      CHICAGO NATURAL HISTORY MUSEUM BULLETIN November 1954 page 4

      Here is first hand evidence of the gradation of this degeneration that Deamer used to support his hypothesis. Evidence from the natural habitat.

      quote :

      Another kind well-known to aquarists is the cave tetra from San Luis Potosi, Mexico. This species reveals a fourstep gradation in the degeneration of the eyes from perfectly eyed, normally pigmented, surface-dwelling individuals to totally blind ones with the eye socket covered with tissue and no evident eye structure

      So it is from the evidence of the natural environment that Deamer claims support for his view.
      Even today we are unable to identify the actual theoretical mechanism of natural selection at work.
      How does Jeffery he put it?

      quote :

      The evolutionary forces that generate these changes are not understood

      If even within micro evolution (which as far as I know everyone accepts) natural selection cannot be identified at work, how is it that the Darwinian process of macro evolution is so certainly propounded as fact?

      Therefore and with great respect, I would encourage both you and canalon to keep away from sweeping statements, unless you are confident you can back them up with evidence.
      btw I have not yet received a reply from Professor Deamer. It is after all the holiday period.

    • #108851
      Nick7
      Participant

      Scottie, I view your arguments and the data you present as very convincing, logical and informative. Also, as I already said, I applaud the effort you applied to learn the subject not immediately relevant to your specialization, and the bravery with which you battle your powerful opposition. Unfortunately, until the detailed explanation is provided about what the “intelligent agency” actually is and by what means it acts on the natural world, I am afraid that the case you present will remain a topic of a casual conversation, but not a scientific symposium. I don’t see how it can be easily done to satisfy the scientific method though.

      This conversation is a flexing of intellectual muscle, not more, not less. It reminds me a ball set in motion in a U-shaped jar. The ball keeps moving in opposite directions driven by the gravity of opposing arguments, but at the end it is really not going anywhere. An intellectually advanced debater can always BS his way out of any situation because reductionist approach to the complexity of life (which has been billions of years in existence by now) can spawn a countless number of explanations. And when the conversation hits dead end, one can always say that the source of the genomic toolkit (and all the mechanisms around it) has either dissolved in Precambrian period without a trace, or will be explained sometime in the future or is hiding in the world beyond the realm of Physics.

      Now the soft-bodied creatures being dissolved, people understand. But there will always be an issue with “selling” the idea of a “super intellectual agency”. I, personally, don’t have a huge problem to make a “leap of faith” to agree with you. But as a former hardcore atheist, I see where your opponents are coming from. However, I do hope the thread will continue its existence, cause it tackles with very important issues of philosophical nature. After all, I am not really sure if I truly care about all of these if at the end our fellow C. elegans will feast on my neatly mapped genome, poop it out, and that will be pretty much the end of this story.

    • #108861
      scottie
      Participant

      Nick7

      Sorry for the delay is responding.
      I deliberately took a couple of days away from the forum just to unfreeze my brain cells. 🙂
      Also to give those who are disposed to reading the papers I refer to, have a chance to digest them.

      I very much appreciate your comments though.

      When I entered this thread back in April I made this point.

      quote :

      Now I don’t get hung up on terminology. When I see design I see it for what it is –Design. I don’t need to prefix it with adjectives such as “Intelligent” as the ID community does or “Apparent” as Richard Dawkins does.

      How did this design come about? Well I don’t see this has been answered by science.
      We haven’t even been able to explain what life is so how can science know how it came about. If it came about by supernatural means then science will never be able to answer it.

      Science however can explain how it could not have come about.

      I have remained consistent on this subject, simply because it is part of my belief system, i.e. the scientific method.
      From the evidence produced I form my conclusions.
      The evidence from science clearly shows me that life could not have got started by any known natural process.
      The evidence also shows, through advances in molecular biology, random mutations of a genome cannot produce the functional design we all see in life processes and this is why Darwinism does not explain these life processes.

      What I have found in any philosophical dogma, is that sooner or later contradictions set in.
      This is so exemplified in this cave animal vestigial and Junk DNA argument.

      Here we have a theory that, at it’s core, describes a process of random mutations of a genome eventually producing function, that another process, natural selection, filters to conserve one particular function, for survival.

      In the case of cave animals however the precise reverse is being argued. Why?
      The reason it seams to me, is to try and preserve natural selection as the filter. We know that these cavefish (for example) are the same species as their surface relatives. They can interbreed, and yet they are arguing mutation has not caused the difference, even though it was the initial cause of the species arriving in the first place. Remember also cave animals are ubiquitous in nature, so this is not some freak happening.

      How can a theory so successfully contradict itself and the adherents not see it?
      I find this quite astonishing.
      My only answer to that question is,– the theory is a philosophical view and not a scientific one.

      I understand the point you are trying to make when you say:-

      quote :

      Unfortunately, until the detailed explanation is provided about what the “intelligent agency” actually is and by what means it acts on the natural world
      I am afraid that the case you present will remain a topic of a casual conversation, but not a scientific symposium. I don’t see how it can be easily done to satisfy the scientific method though.

      With respect I have to disagree with you. It is the scientific method that is falsifying the fundamental tenets of evolutionary theory. Its promoters claim it to be genuine science, therefore it should be judged by the scientific method.

      However is the scientific method falsifying design by an outside agency?
      It is certainly not falsifying the design argument, so that leaves the “outside agency” bit.

      Now if, by argument the case is as you are implying, that an actual description of the agency must be supplied for it to be treated scientifically, then there should be consistency in this argument for both sides.
      So does the theory or indeed any evolutionary scientist know what the common ancestor, sitting at the base of the TOL is or was?
      Ok let’s make it easier.
      Does the theory or any scientist describe the common ancestor of the human/ape lineage, or the common ancestor of the bear/panda lineage?
      I know what the answer is.

      Junk DNA was used as proof of evolutionary theory. Now as it has become clear that these areas are in fact very much functional most are simply burying their heads in the sand or trying to find ways to show how it does in fact support evolutionary theory.
      So no matter what the evidence, it supports evolution.
      Sounds very philosophical to me and certainly not scientific.

      I would like to post some more information on what the latest research is revealing on mouse, rats and humans, but that had better wait for the moment.

    • #108864
      Gavin
      Participant

      I can’t figure out why you’re still going on about this, scottie. You believe in the Creator Thing and others do not. Science cannot prove or disprove its existence. Your "disproofs" of evolution are (embarrassingly) feeble compared to the weight of evidence in its support. The only people who do not support evolution are those who are ignorant of the evidence and those who WANT to believe in something else. The lack of scientific proof of a natural cause of whatever does NOT LOGICALLY LEAD to the existence of a Creator Thing. You are CHOOSING to believe in it, because you apparently WANT it to exist, not because any great body of evidence supports its existence or fails to support a naturalistic explanation. So why are you devoting so much time and effort to this thread? It’s very apparent that you must be spending HUGE amounts of time on this project, but I can’t for the life of me figure out what your project is. Are you on a personal quest to convince one part of your brain of something that another part refuses to accept? Or what. exactly?

    • #108869
      Nick7
      Participant

      Gavin, here is your statement: “The only people who do not support evolution are those who are ignorant of the evidence…”
      And here is definition of evolution: “Evolution is any change across successive generations in the heritable characteristics of biological populations.” (Wiki)

      Now, I may have a serious problem with my English, cause I haven’t noticed here anything that would’ve contradicted the abovementioned description of evolution. The label of “evolution denier” is frequently used just like a “holocaust denier” and people rarely bother to explain what they actually mean by that. If Scottie questioned the randomness role behind genetic or epigenetic complexity / abiogenesis or saltation, then I still don’t see what exactly the evidence you are talking about is. Perhaps I have to admit my ignorance (and I already did that) and acquire a PhD in biology to see your point? But here is the dilemma – I’ve never seen anyone questioning the validity of the Pythagorean theorem, but I saw PhD-s clashing over the randomness as one of the key elements of the evolution from the first amino acid to a man. So maybe it’s not ignorance that causing the issues here… Maybe the only possible alternative to randomness – supernatural involvement being that, is causing the controversy…

      On a personal note… One time I ran into event, 2 degrees later, I have absolutely no natural explanation to. What was it is irrelevant and it didn’t really prove anything specific, but it has absolutely reshuffled the weights I allocated to the elements in the equation of my perception of reality. Putting aside charlatanism, circus tricks, and misunderstood natural phenomenon, the supernatural to me is no longer multiplied by zero. Now I view it as being relevant to some form of rare phenomenon superior to our level of knowledge & superior to our ability to readily sense and perceive the reality from which it originated.

      Let me mention the quote C. Venter is credited with: “…we are literally coming out of the dark ages of biology. As a civilization, we know far less than one per cent of what will be known about biology, human physiology, and medicine. My view of biology is ‘We don’t know s*%t.’ " http://www.mindfully.org/GE/Venter-Genome-Warrior12jun00.htm
      I would rephrase him in a broader sense – we still don’t know s*%t about reality that surrounds us. We’re all balancing on the scales of our believes systems, and direction in which the scales tip depends a lot on our personal experiences. The scientific method helps us to objectively filter out mumbo-jumbo portion of these experiences, but I’m afraid the limitations of our sensory capabilities sometimes impair it severely, feeding the believes in impossibility of something that might as well be possible.

      I can only repeat what I already said – I’m not qualified to embrace Scotties case, but I don’t see any grounds to firmly reject it except the ones rooted in some form of religious atheism (and ignorance doesn’t seem to be a part of the picture here). Maybe if his arguments were predominantly discussed and judged on their own merits, the discussion would be more beneficial.

    • #108873
      scottie
      Participant

      Gavin

      I am not trying to get anyone to believe in the “Creator thing” as you call it.
      What I am trying to do is put my understanding of science (biology in this case) to the test regarding the purpose of this thread. “Theories – Origin of life”.

      quote :

      Your “disproofs” of evolution are (embarrassingly) feeble compared to the weight of evidence in its support.

      I can only point to the evidence that supports my understanding. If the “weight of evidence” as you put it supports your position then surely my feeble disproof’s should be easily countered with evidence.
      Remember you did try, when you took up my challenge to reveal what would falsify “neo Darwinism”.

      The weight of evidence does pile up in favour of the concept of micro evolution, which of course is variation within species.
      But this discussion is about more. Darwin’s whole view was about speciation, not variation within species.
      Now you have quite clearly stated that you prefer to accept the mechanism of variation within species to extend across to producing new species.
      I don’t see that evidence and post accordingly. This is a perfectly acceptable scientific position to take.
      For philosophical reasons you choose to disagree. I certainly don’t have a problem with that, in fact I commend you and indeed have done for being honest enough to acknowledge that.
      You are also correct

      quote :

      The lack of scientific proof of a natural cause of whatever does NOT LOGICALLY LEAD to the existence of a Creator Thing.

      Is it not also the case that functional design can lead logically to a designer.
      In the end it boils down to the scientific evidence, and that is where I am coming from.

      I am passionate about science, I also have enough time and inclination to delve into the subject and bore every one silly with my findings.

      I believe Nick7 makes a valid point when he says

      quote :

      I don’t see any grounds to firmly reject it except the ones rooted in some form of religious atheism

      You have acknowledged this but others have chosen to engage in rhetoric rather than produce evidence which stacks up.

      If evolutionary theory is correct then I will readily endorse it. Put me to the test.

      Do keep in mind that there are many religious people who endorse the Darwinian process.

      Just go to the BioLogos Foundation site started by Francis Collins who is one of the top geneticists and headed the Human Genome Project, and is now Director of the National Institutes of Health

      This is being made into a religious issue. Why?
      Darwinism is not the sole prerogative of atheism.

    • #108875
      Gavin
      Participant

      scottie

      You see design in nature and argue that there must be a designer (a bit tautological, that). By accepting design as a given, you cannot lay any claim to scientific rigour. Science must assume that supernatural forces are not responsible for whatever is being studied. Science does not (cannot) rely on proof, just probability based on the available evidence. The available evidence does not lean toward any design in nature. Design is a preconception, not an observation. You can believe whatever you want, but please don’t try to claim that science supports your beliefs. You may be passionate about what you think science is, but cherry-picking in science leads to bad science. All scientists plough through the literature trying to find support for their pet theories, but they cannot ignore the findings that contradict their theories. Please don’t dismiss evidence that doesn’t support what you want to be true. Doing so doesn’t make it true. And is not good science.

    • #108880
      scottie
      Participant

      Gavin

      quote :

      You see design in nature and argue that there must be a designer (a bit tautological, that).

      That is an interesting statement.
      But trying to move the goal posts into the philosophical area won’t work, and for this reason.

      You could have a case if I did not define how my argument for functional design could be falsified.
      However I have done precisely that, and it is about where you entered into this discussion. Remember!

      quote :

      scottie » Tue Jun 21, 2011 10:20 pm

      To be regarded as science then it must be falsifiable.
      So once again, is this understanding falsifiable?
      I answer Yes, it can be falsified, and there is nothing “secretive” about this.

      Every one is aware that functional design (whether good, or not so good or even downright bad) displays itself with certain properties.
      1) The function has a purpose. ( i.e. It goes from A to B with C as it’s goal )
      2) Method by which that purpose is achieved. (How does it go from A to B)
      3) It would not contain parts or units that had no function toward the purpose.

      Therefore, falsifying this hypothesis would require that parts of the genome were non functional. Now if that was the case then that would be an argument against my hypothesis.

      So, all you have to do provide evidence that any part(s) of the genome are non functional and my hypothesis is in trouble.
      There you are, I have told you what you need to show.
      Should be quite simple, shouldn’t it?

      Now you tried to falsify and failed with the phylogenetic data and tree building.. argument

      However where have you or indeed anyone even attempted to define how Darwinism could be falsified?
      The simple answer is that there has not been even an attempt to do so.
      This lack of defining even a falsifiable trait limits Darwinism to a philosophy,
      and you have in fact acknowledged that.

      Remember your own words
      about14351-336.html

      quote :

      Gavin » Fri Nov 18, 2011 5:17 pm
      …. The thought of a purely naturalistic, purposeless origin for everything also seems to be very comforting to me. But then I’m quite irresponsible – if there’s no cosmic purpose, then I’m off the hook for pulling my weight.

      You now appear to be trying to row back from your own statement of belief by suggesting that the verifiable evidence I have produced is only a product of my belief.

      Your description of what is science, does deserve a comment. You might find these descriptions of science helpful.

      http://www.gly.uga.edu/railsback/1122sciencedefns.html

      I particularly like Richard Feynman’s comment.

      quote :

      Science alone of all the subjects contains within itself the lesson of the danger of belief in the infallibility of the greatest teachers in the preceeding generation . . .As a matter of fact, I can also define science another way: Science is the belief in the ignorance of experts.
      Richard Feynman, Nobel-prize-winning physicist,
      in The Pleasure of Finding Things Out
      as quoted in American Scientist v. 87, p. 462 (1999).

      🙂

    • #108882
      Gavin
      Participant
      quote scottie:

      But trying to move the goal posts into the philosophical area won’t work, and for this reason.

      The goal posts are already philosophical. I haven’t moved them.

      quote scottie:

      Every one is aware that functional design (whether good, or not so good or even downright bad) displays itself with certain properties.
      1) The function has a purpose. ( i.e. It goes from A to B with C as it’s goal )
      2) Method by which that purpose is achieved. (How does it go from A to B)
      3) It would not contain parts or units that had no function toward the purpose.

      Why should these properties be limited to design?

      quote scottie:

      Now you tried to falsify and failed with the phylogenetic data and tree building.. argument

      I don’t recall having failed. I think I said something like evolution being falsified if phylogenetic trees could not be built, and you resorted to the creationist Cambrian argument, and I resorted to how science works and how an incomplete fossil record is not an observation. How does this constitute failure? Ignoring the myriad of trees that have been built from the available evidence is an example of how you are selectively discounting the available evidence that doesn’t support your beliefs. Sure, the tree is not complete, but are the gaps in an otherwise rather impressive assemblage MORE LIKELY to represent disproof of the whole or an incomplete collection or availability of evidence?

      quote scottie:

      However where have you or indeed anyone even attempted to define how Darwinism could be falsified?

      I think it was Jerry Coyne who said that he would abandon his belief in evolution if a human fossil were ever found in Cretaceous strata. This is just one of many proposed examples of how evolution could be falsified. Darwin also mentioned a few examples. The inability to build phylogenetic trees, that I proposed above but that you seem to have forgotten, is another.

      quote scottie:

      You now appear to be trying to row back from your own statement of belief by suggesting that the verifiable evidence I have produced is only a product of my belief.

      I have only said that you are selectively cherry picking a small subset of the available evidence and discounting the larger subset. The cherry picking is a product of your belief, not the evidence.

      quote scottie:

      I particularly like Richard Feynman’s comment.

      quote :

      Science alone of all the subjects contains within itself the lesson of the danger of belief in the infallibility of the greatest teachers in the preceeding generation . . .As a matter of fact, I can also define science another way: Science is the belief in the ignorance of experts.

      Feynman said lots of interesting things. He also said, "God was invented to explain mystery. God is always invented to explain those things that you do not understand. Now, when you finally discover how something works, you get some laws which you’re taking away from God; you don’t need him anymore. But you need him for the other mysteries. So therefore you leave him to create the universe because we haven’t figured that out yet; you need him for understanding those things which you don’t believe the laws will explain, such as consciousness, or why you only live to a certain length of time – life and death – stuff like that. God is always associated with those things that you do not understand."

    • #108885
      JackBean
      Participant

      scottie, you have not responded to this. And you know what I like most to do, right?

      quote JackBean:

      So far, although you were bullshitting with non-sense, I have respected you at least because you were stick with your opinion, no matter, how silly it may be. But I see, you are neglegting yourself already.

      about14351-336.html

      quote JackBean:

      scottie, I’m sure you will first answer my very old question, right?

      quote JackBean:

      You have not again said, how did the humans appear on Earth. Try to read this carefully and pick one possibility (or come up with other, but do not start about lysosomes :roll:)
      1) they were created when all the other life on Earth was created few billions of years ago
      2) they were created few tens/hundreds thousands of years ago when the creator was bored again and had no forum to post on
      3) they evolved from lower animals, no matter, whether these were created or arose spontanneously

      you said, that 1 and 3 are wrong, so the creator “arrived” several times on Earth and worked on schifts, right? That would at least explain, why we don’t find fossils of recent animals in say Mesozoic era.

      quote scottie:

      Jackbean

      The No 2 option of yours is the nearest to my view without of course the rather silly appendage you have attached.

      Another thing you have not responded to:

      quote JackBean:

      The simple question is this.
      Is intelligent design actually supported by evidence or is it simply your belief that it is.

      Since you require evidence for evolution, how is that, that you do not require one for ID?

      quote scottie:

      quote :

      Right, they are all wrong, all the evolutionists, all IDers and all creators are wrong, but one retired engineer with no biological knowledge is right

      My major point seems to have escaped your understanding.

      If evolutionary theory (in all it’s various forms) is correct then there will be no disagreement between the theorists as to what the mechanism that drives macro evolution actually is.
      The reality that different dissenting views not only exist but are actually competing for prominence demonstrates that the mechanism is not known.
      The only common thread that unites the various adherents is that a naturalistic cause is the only one that is acceptable, regardless of where the evidence leads.

      This makes any of these theories philosophically based. That is not a view I have any difficulty with, other than the point that it is regarded as a scientific fact and any dissension from that view is regarded as intolerable and therefore worthy of censorship, as you yourself have so plainly demonstrated.

      Imagine, that we are able to travel in time and transfer say a car into medieval times. They will try to explain, how the car functions, but none of them will be probably right, since they don’t have enough knowledge. Does that mean that the car doesn’t work?

    • #108911
      scottie
      Participant

      Gavin

      quote :

      The goal posts are already philosophical. I haven’t moved them.

      You have said it all.
      Evolutionary theory is philosophical, which is what I have always been saying.

      This thread is about scientific theories of Origin, and I am arguing that Darwinian theory is not backed up with scientific evidence. It is supported by a philosophy.
      I am providing evidence that backs up my claim and you respond that I am being selective in presenting the evidence.

      If I am selective, then please present the evidence that opposes my understanding, but not with vague statements like “ the weight of evidence” or

      quote :

      “Ignoring the myriad of trees that have been built from the available evidence is an example of how you are selectively discounting the available evidence that doesn’t support your beliefs”

      If this evidence is based on science and not philosophy then it can be examined scientifically for its veracity.

      So why don’t you just produce a phylogenetic tree and lets examine it scientifically.
      Just one other point

      quote :

      Every one is aware that functional design (whether good, or not so good or even downright bad) displays itself with certain properties.
      1) The function has a purpose. ( i.e. It goes from A to B with C as it’s goal )
      2) Method by which that purpose is achieved. (How does it go from A to B)
      3) It would not contain parts or units that had no function toward the purpose.

      Why should these properties be limited to design?

      Gavin, you are arguing against yourself now.
      How on earth can a process on the one hand be random and undirected and at the same time be purposeful?

      quote :

      I think it was Jerry Coyne who said that he would abandon his belief in evolution if a human fossil were ever found in Cretaceous strata.

      Jerry Coyne is on a pretty safe bet here.
      Even many Creationists would go along with that one 🙂
      Oh and I would be quite happy to examine the contradictions and circular arguments in his book "Why evolution is true." at another time.

      Now I am not looking for answers to these ones just making the point.

      However can we just concentrate on an example of a phylogenetic tree so we can discuss it scientifically.

      Please don’t feel you have to rush a response, just carefully choose an example and cover all the angles you can think of.
      I say this because I do sincerely have respect for your views even though we part company on some.

      In the meantime I will present some more evidence to ponder on.
      This time it covers the whole structure of a genome and the evidence that has emerged.

    • #108913
      scottie
      Participant

      Gavin Here is some more evidence, this time on Isochores
      Erwin Chargaff identified two Rules governing DNA.
      The first which gave Watson and Crick the necessary leg-up in identifying the structure of DNA.
      These 4 nucleotide bases are Adenine (A), Thymine (T), Cytosine (C), Guarnine (G)
      Chargaffs Rules govern two things.

      1) Adenine(T) always pairs with Thymine (T) and are in equal amounts
      Guanine (G) and Cytosine (C) always paired and are in equal amounts.
      2) The ratio of the amounts (G+C) and (A+T) varies from species to Species and is universal. (Chargaff’s C+G% rule)
      In other words this ratio is species specific.

      There are large regions of DNA (greater than 300 KB) with a high degree uniformity in G-C and C-G (collectively GC) and these regions tend to have more genes, and important genome features are dependent on these isochore regions or structures, e.g. genes are found predominantly in the GC-richest isochore classes.
      http://www.ncbi.nlm.nih.gov/pubmed/11591471

      Here is an abstract from a paper that emphasises importance of these isochore structures.
      http://www.ncbi.nlm.nih.gov/pubmed/11433361 2001

      quote :

      Abstract
      One of the most striking features of mammalian chromosomes is the variation in G+C content that occurs over scales of hundreds of kilobases to megabases, the so-called ‘isochore’ structure of the human genome. This variation in base composition affects both coding and non-coding sequences and seems to reflect a fundamental level of genome organization. However, although we have known about isochores for over 25 years, we still have a poor understanding of why they exist.

      So an outstanding feature of eukaryote genomes is this segmentation of the DNA into these isochore regions, each with a distinctive species specific base composition.

      Therefore to view the genome without reference to it’s isochore mosaic would be like describing, say, the Colorado River without any reference to the Grand Canyon, or the Grand Canyon National Park, Colorado desert or Horseshoe bend etc etc, the very structures that guide and direct the river to its destination into the gulf of California.

      However the fact is that most of us view the genome in precisely this manner.
      This means that although we acknowledge the fact of the genetic code, (how did that come about I wonder) we almost always are oblivious to this other level of information that organises the genome, and another thing, remember also that each genome organisation is species specific.

      If a graph is drawn of the relative densities of GC we would get an undulating line of hills and valleys, with the gene distribution being mainly around the hill sections of the genome

      This type of graph is precisely what the authors of a paper appearing in Nature plotted.
      The paper is entitled
      Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
      Rat Genome Sequencing Project Consortium*
      *Lists of participants and affiliations appear at the end of the paper
      http://www.nature.com/nature/journal/v4 … e02426.pdf.
      The principle author of this paper is Francis Collins,.along with some 150 or so other researchers.( I stopped counting after about 100)

      Now why is this significant as far a evolutionary theory is concerned.?
      Because it reaches directly into the issue of Darwinian speciation.

      If you bring up the paper in a separate tab and scroll down to page 502 of this paper you will notice 4 graphs in figure 9

      Let just examine the graph 9c labelled “Lineage specific SINE content”
      The X axis represents some 110 million base pair segment of the Rat chromosome 10.
      The Y axis Red line represents the Rat specific SINE distribution.
      The Green line represents the corresponding distribution in the Mouse genome.
      It is quite noticeable that the two demonstrate a remarkable similarity. In fact it could be argued that one is a copy of the other with a few minor amendments.

      Each graph denotes only lineage specific mutational insertions affecting mostly the so called Junk DNA.
      Now here is the rub.
      Evolutionary theory posits that the Rat and Mouse diverged from a common ancestor some 20 odd millions years ago.

      So what we are seeing are two independent random mutational processes acting on Junk DNA over a period of some 20 million years and both processes randomly produce the same high order result.

      What are the chances of an undirected random process producing this result?
      If anyone wishes to believe in miracles, then you are staring at one.

      On page 509 Collins discusses this finding under the heading

      quote :

      Co-localization of SINEs in rat and mouse
      Despite the different fates of SINE families, the number of SINEs inserted after speciation in each lineage is remarkably similar:,300,000 copies……Figure 9c displays the lineage-specific SINE densities on rat chromosome 10 and in the mouse orthologous blocks, showing a stronger correlation than any other feature. The cause of the unusual distribution patterns of SINEs, accumulating in gene-rich regions where other interspersed repeats are scarce, is apparently a conserved feature, independent of the primary sequence of the SINE and effective over regions smaller than isochores.

      Notice how this reference to isochors is just glossed over. Why? Because Junk DNA is becoming an embarrassment It was used by Jerry Coyne amongst others as proof of Darwinian evolution. Now it is viewed as conserved, but lets not dwell too loudly on that.

      When looking for functionality the first thing geneticists try to spot is a distinct non random pattern. This is what we have here and we all know what non random functional patterns reveal. 🙂

      However since an outside agent cannot be considered we are left with random mutations being the miracle worker.
      So am I being selective. Well we can examine the other graphs if anyone wishes.
      btw the Human genome produces the same pattern.
      The whole genome is an organised entity as is being clearly demonstrated, not the cobbling together of random undirected mutations.

    • #108930
      Gavin
      Participant

      scottie, are you sure you’re not a creationist? You seem to use their tactics a lot. Gee, science doesn’t have a good answer for this. I guess god must have done it. When science has figured out everything, we’ll get back to you. Until then, read the last paragraph of the section you quoted from.

    • #108963
      scottie
      Participant

      Gavin
      Sorry for the delay, on my travels away again.

      I am disappointed that you are so reluctant to engage in the science underpinning your view.

      quote :

      are you sure you’re not a creationist? You seem to use their tactics a lot. Gee, science doesn’t have a good answer for this. I guess god must have done it.

      Actually science reveals the right answer. The evidence from science is demonstrating that this view you are presenting cannot be supported by random and unguided natural processes.

      If you are suggestion that I am using creationist tactics then they must be well pleased with your "compliment" because I have been presenting only the evidence that science itself reveals.

      Your reference to the last paragraph which I have quite naturally read, states

      quote :

      These phenomena, in conjunction with an overall trend in substitution rates towards AT-richness, suggest a model in which quickly evolving regions accumulate a higher-than-average AT content, which attracts LINE elements. Although distinct cause– effect relationships such as this remain largely speculative, these results reinforce the idea that local genomic context strongly shapes local genomic features and rates of evolution.

      Isn’t this is the way science works.
      One looks at the evidence, then formulates a hypothesis that can explain it, paying particular attention to stating clearly what the assumptions that underpin that hypothesis are based on.

      Now when speculation is the best some of these scientists can come up with, you either run with that speculation or call it for what it is.
      That is all I am doing.
      I realize it is upsetting to you but I didn’t join this forum to run with the crowd or indeed be intimidated by it.

      quote :

      When science has figured out everything, we’ll get back to you.

      Who is the We ? 🙂

      You seem to be confusions one noun "science" with another "scientists"
      Is that not rather presumptuous?

    • #108964
      LeoPol
      Participant

      Hi! Thus, the origin of life began with the origin of the mind. And then the mind, picked up the knowledge and created a polypeptide-nucleic technology! Armed with this technology and has spread throughout the universe.

      (Comment 101 by LeoPolishchuk)
      http://richarddawkins.net/articles/6435 … egin#page4

      "In order for a origin of membrane – much organic matter is not necessary – only the membrane lipids of different isoforms, it is necessary also to a weak emission core of the star created a flow of heat through the surface phase transition, and yet not interfere with a certain oscillation – vibration … In general, all this is difficult to discuss now, not yet studied the process of emergence and functioning in a natural cell membrane of this very … – Active situational model – a kind of natural intelligence and personality!! But when it all becomes clear, then we can speculate about the conditions and awakening him on the protostar, or on some planet out there."

    • #108966
      Gavin
      Participant
      quote scottie:

      I am disappointed that you are so reluctant to engage in the science underpinning your view.

      Experience has taught me that doing so is futile. Closed minds are difficult to reason with. The issue is neither the lack of evidence supporting evolution nor the wealth of evidence supporting supernatural creators, but why we all believe what we do.

      quote scottie:

      The evidence from science is demonstrating that this view you are presenting cannot be supported by random and unguided natural processes.

      Few natural processes are random, but they do appear to be guided – by natural laws.

      quote scottie:

      Now when speculation is the best some of these scientists can come up with, you either run with that speculation or call it for what it is.
      That is all I am doing.

      In the absence of answers, speculation is all we can do. But speculation is the source of further research. You haven’t convinced me that your belief in a supernatural creator is speculation on your part.

      quote scottie:

      Who is the We ?

      "We" are the forum members who understand how science works.

      quote scottie:

      You seem to be confusions one noun “science” with another “scientists”
      Is that not rather presumptuous?

      No. I don’t see any other group using a systematic, rational approach to looking for answers.

    • #108985
      scottie
      Participant

      Gavin

      quote :

      scottie wrote:Who is the We ?

      “We” are the forum members who understand how science works.

      Would you mind terribly if I demonstrate how I understand science works and perhaps any forum members could then comment whether my understanding is correct.
      Perhaps a good start could be by putting the case for phylogenitic trees that you introduced but the details of which you now don’t wish to discuss.
      Below is a broad paraphrase description from wiki that I essentially agree with.

      A phylogenetic tree is a branching diagram or "tree" showing the inferred evolutionary relationships among various biological species or other entities based upon similarities and differences in their physical and/or genetic characteristics.
      The taxa joined together in the tree are implied (or inferred) to have descended from a common ancestor.

      The website talkorigins has a very good primer on this subject.. A lot of it is very technical but much of it is understandable even to a layman such as me.
      http://www.talkorigins.org/faqs/comdesc/phylo.html

      At the very end of this primer is the subheading

      quote :

      Caveats with Phylogenetic Inference
      As with any investigational scientific method, certain conditions must hold in order for the results to be reliable. A common premise of all molecular phylogenetic methods is that genes are transmitted via vertical, lineal inheritance, i.e. from ancestor to descendant.
      If this premise is violated, gene trees will never recapitulate an organismic phylogeny.

      This assumption is violated in instances of horizontal transfer, e.g. in transformation of a bacterium by a DNA plasmid, or in retroviral insertion into a host’s genome. During the early evolution of life, before the advent of multicellular organisms, horizontal transfer was likely very frequent (as it is today in the observed evolution of bacteria and other unicellular organisms). Thus, it is questionable whether molecular methods are applicable, even in principle, to resolving the phylogeny of the early evolution of life near the most recent common ancestor of all living organisms

      (my emphasis)
      It then goes on to list some of the some of the more important caveats. (about 11 in total)
      This is all coming from an evolutionary site and is a very honest presentation of the evidence.

      Please note the expression “phylogenetic Inference”.

      Now it is very clear that the hypothesis of Horizontal Gene Transfer has considerably muddied the waters in establishing the tree of life and hence common ancestry
      So as this site recognises, it was very common in prokaryotes and thus the last universal common ancestor cannot be determined through molecular means.
      The base of the tree therefore cannot be distinguished in any diagram..

      Since HGT is inferred to have played such a ubiquitous role in early evolution, I would suggest perhaps HGT also needs an explanation.
      Can anyone please assist?

    • #108986
      JackBean
      Participant
      quote Gavin:

      scottie, are you sure you’re not a creationist? You seem to use their tactics a lot.

      agree, quote mining, avoiding unwanted topics etc.

    • #108987
      Gavin
      Participant

      scottie

      You’re getting back to the crux of the matter by addressing the issue of scientific inference. In the absence of absolute truth, inference, through inductive and deductive reasoning, and based on the available evidence, is the best we can do. No phylogenetic tree, or anything else for that matter, is proven to be perfectly known. We can only collect data and propose probabilities based on those data. New data often force revisions. We will likely never be able to build a complete tree of life that will have any substantial probability of accuracy, and we will certainly never KNOW any tree to be accurate, especially for the early stages of life where things like HGT have muddied the waters. I don’t know that evolution is true any more than you know that your creator exists. But the body of evidence collected to date favours evolution more than it favours creation – by a large margin. You may interpret the evidence to favour your beliefs all you want, but doing so will have little impact on the scientific world.

      As I keep saying, you believe what you want to be true. The evidence points elsewhere.

    • #108999
      scottie
      Participant

      Gavin
      I agree with just about everything you have said except the last two sentences.
      It is in the area where you state that the weight of evidence falls in favour of Darwinism that you are unable substantiate.
      It is in just this area that I have been producing the weight of evidence and citing the peer reviewed support for it that you have been unable to contradict.

      The only argument that you seem able to produce is by way of vague statements
      like

      quote :

      But the body of evidence collected to date favours evolution more than it favours creation – by a large margin.

      A statement like that should be backed up, not just made.
      I am backing up my argument from actual evidence reported on by evolutionary scientists themselves.

      However I do give you much credit for acknowledging that your stand is essentially a philosophical one, and one with which I have no problems because I take it to be a sincere one

      However it is when you say it is backed by science then I respond that you really have to demonstrate that.
      The weight of evidence that you keep referring to is evidence that supports variation within species.
      I don’t think even the so called "creationists" who believe that life somehow continues after death, disputes that fact.

      I find it difficult why on a biological blog no one is prepared to, for instance, engage on the subject of HGT.

      Why?
      it’s a perfectly valid biological subject, one that prompted a lot of detailed research.

      You apart, I sense some trepidation to engage in anything that can be analysed scientifically.

      So I ask again, is anyone prepared to at least engage on HGT as it impacts on the very subject you yourself introduced.

    • #109001
      Gavin
      Participant

      You’re becoming tiresome, scottie. If you really want to believe that science favours the existence of a creator over evolution, then go ahead. Your faith is stronger than your ability to reason and seems unshakeable, so any effort on my part to shake it appears to be futile. Science requires an open mind to be effective.

      Don’t be too offended if members of the forum don’t take you seriously. We get many deniers here, and sometimes we just get tired of them, or annoyed with them. I’m not annoyed, but I am tired.

    • #109002
      scottie
      Participant

      Gavin

      quote :

      Don’t be too offended if members of the forum don’t take you seriously. We get many deniers here, and sometimes we just get tired of them, or annoyed with them. I’m not annoyed, but I am tired.

      Why on earth should I be offended. You have a view and I have a view.
      However what is it that I deny?
      Is it Science or your philosophy?
      I am simply presenting the evidence of science and you are presenting the philosophy.

      Now you surely cant deny that?

      The views on this thread are increasing by over 1500 on average per day.
      It seems many are quite far from getting bored, unless of course they enjoy being bored. 🙂

      Gavin I don’t except you to respond, but at least listen to what evolutionary scientists themselves are saying.
      Not the ones who write books denying the evidence, but the ones who are actually doing the research and acknowledging the difficulties Darwin has created.
      I am not simply an outsider denying Darwinism. My roots are firmly within science.
      The denying is coming from within the evolutionary community itself.
      You may not wan’t to embrace my design view and I don’t have a problem with that, but at least acknowledge the evidence against Darwinism.

      As I see it, the problem you are faced with is that your materialist view (and I have due respect for that) has led you into accepting a dogma, one that insists Darwinism and Science are one and the same thing and anything that disagrees with it is not scientific.

      Well the situation is, the evidence from scientific research is rapidly unraveling that dogma and I fully understand how difficult it must be to come to terms with it.

      However the scientific method is what matters in the end, and adhering to that is what advances knowledge and understanding.

      Perhaps if I press ahead with the case for HGT as presented by the evolutionary community maybe I and perhaps others can learn some more.

    • #109018
      scottie
      Participant

      Horizontal Gene Transfer and the Tree of Life
      A common premise of all molecular phylogenetic methods is that genes are transmitted via vertical, lineal inheritance, i.e. from ancestor to descendant.

      It was anticipated that this method would demonstrate the Darwinisn mechanism of common decent, and the universal tree of life would be vindicated.

      However these molecular comparisons began producing some very contradictory results.
      The hoped for Darwinian Tree of Life (TOL) simply has turned out to be more of a bush or even forest.

      The largest biomedical research facility in the world is the National Institutes of Health with its subdivisions, National Center for Biotechnology Information, National Library of Medicine, at Bethesda, MD USA.

      This is what Eugene Koonin it’s Senior Investigator along with colleges presented in their paper in 2001

      http://www.ncbi.nlm.nih.gov/books/NBK2228/
      Horizontal Gene Transfer in Prokaryotes: Quantification and Classification
      Eugene V. Koonin,1 Kira S. Makarova,1,2 and L. Aravind2.
      Annu. Rev. Microbiol. 2001. 55:709 – 42.

      quote :

      Horizontal (lateral) gene transfer, the transfer of genes between different species, is an evolutionary phenomenon whose extent and even very existence have been the subject of a longtime debate that tends to become particularly vigorous when cases of horizontal gene transfer that involve eukaryotes are considered (98, 103). This is understandable because (a) horizontal gene transfer seems to challenge the traditional, tree-based view of the evolution of life and the core neo-Darwinist belief in the central role of reproductive isolation between species in evolution (21–23, 53, 74, 89, 90) concepts that, at least initially, have been developed in studies on the evolution of sexually reproducing eukaryotes, and (b) like many evolutionary phenomena, horizontal transfer is hard to prove unambiguously.

      Eight years later and as a result of more accumulated evidence Koonin and colleges present some more findings.

      http://www.ncbi.nlm.nih.gov/pubmed/19594957
      Search for a ‘Tree of Life’ in the thicket of the phylogenetic forest. (2009)
      Puigbò P, Wolf YI, Koonin EV.

      quote :

      CONCLUSIONS:
      Horizontal gene transfer is pervasive among prokaryotes: very few gene trees are fully consistent, making the original tree of life concept obsolete. A central trend that most probably represents vertical inheritance is discernible throughout the evolution of archaea and bacteria, although compressed cladogenesis complicates unambiguous resolution of the relationships between the major archaeal and bacterial clades.

      So lets try and bring this up to date.
      A team of researchers has attempted to produce a new model of decent.
      They have termed it the “Rooted Nest of Life”.
      http://www.ncbi.nlm.nih.gov/pmc/article … ool=pubmed
      A Rooted Net of Life 2011
      David Williams, #1 Gregory P Fournier, #2 Pascal Lapierre,3Kristen S Swithers,1 Anna G Green,1 Cheryl P Andam,1 and J Peter Gogarten 1

      All papers are reviewed by expert reviewers before publication
      Reviewer 1: W. Ford Doolittle, Dalhousie University Comments ( He is regarded as one of the foremost researchers in this field. Here is an extract of his comments.

      quote :

      Reviewer 1 continued: Second, we might ask why the microbial systematics and evolution community still feels that we need some single way of describing the relationships of organisms and some singly historical "metanarrative" to undergird it. I’d guess our colleagues doing human linguistic, cultural and social history would see this as an unnecessarily simplistic and ultimately misleading aspiration (see for instance [95]). Is it just our need to defend Darwinism from its politically powerful opponents that causes us to cling to it?

      Authors’ response: This is a fascinating question. In the context of this manuscript, we make the assumption that there is a single "true" sequence of events or organization of matter on the temporal and spatial biological scale (i.e., Life on Earth). The goal of reconstructing the resulting relationships between organisms is therefore to recover a single, historical description – but any such attempts are limited by the methods used and the data available (which at present do impose limitations on the confidence of historical events/relationships).

      Reviewer 2 continued: Eric Bapteste, Université Pierre et Marie Curie
      The authors suggest that rooting the ribosomal tree of life should help by polarizing the complex reticulations of the many gene trees mapped onto it. This seems optimistic: individual gene phylogenies can be so messy (due to duplication, losses, and recombinational lateral gene transfer in addition to speciation) that even knowing how to root the ribosomal tree may not be that decisive for the polarization of these gene trees.

      Authors’ response: We agree that mapping a gene tree onto the ribosomal scaffold is a complex, non-trivial process that needs to consider probabilities of gene duplications, gene loss, and gene transfer. Certainly, mapping a gene with sporadic disjoint distribution will need to incorporate gene transfer relative to the ribosomal scaffold. Furthermore, the comment on messiness is entirely correct. In many instances multiple mappings are possible, especially if extinct and unsampled lineages are taken into consideration. Especially for small gene families the distinction between gene-transfer donor and recipient often is not possible. The identification of donors and recipients is certainly probabilistic and not absolute. However, these limitations not withstanding, the availability of a rooted reference tree greatly facilitates the integration between gene and reference tree

      There is a lot more but is this not enough to sum up the case against TOL.
      But what about the “messy bit” Horizontal Gene Transfer.
      Well lets keep that for the next post as this one is probably long enough.

    • #109024
      JackBean
      Participant

      So? How does horizontal gene transfer in bacteria disproof evolution (in eukaryotes)?

    • #109025
      scottie
      Participant

      JackBean

      quote :

      So? How does horizontal gene transfer in bacteria disproof evolution (in eukaryotes)?

      The hypothesis of HGT militates against common decent and therefore the tree of life concept as posited by Darwin and also the neo Darwinian synthesis.

      This is why there is such a vigorous debate between the opposing views within the evolutionary community, hence Koonin et al’s observation that I quoted.

      quote :

      “horizontal gene transfer seems to challenge the traditional, tree-based view of the evolution of life and the core neo-Darwinist belief in the central role of reproductive isolation between species in evolution”

      And HGT is the hypothesis that is intended to explain the reason why molecular phylogenetic trees produce such contradictory results.

      HGT doesn’t disprove any evolutionary process. It disproves the core Darwinian concept of decent from a universal common ancestor.

      Please remember the phylogenetic tree was intended to prove common decent from a universal common ancestor and the tree of life diagram has been used to explain the common and vertical inheritance from that ancestor.

      I hope I have explained that more clearly.

      However the HGT has it’s own difficulties as well as I hope to show next.

    • #109028
      wbla3335
      Participant

      Scottie

      Few, if any, evolutionary biologists deny that HGT complicates the construction of prokaryotic trees. I doubt that any evolutionary biologist would consider this a problem for evolutionary theory. You contend that anything other than a simple, unambiguous, linear tree of life disproves evolution. No one educated in the biological sciences would make such a contention. When I looked at the parts of the quotes that you have put in bold in your posts, it became very clear that you do not understand what these people are saying. They are saying that evolutionary history is complex, not that it is wrong. As Jack has urged, please clarify why you think that HGT falsifies evolutionary theory. Specifically, please provide support that these authors, particularly Koonin, think evolution is bogus. You should thoroughly research something before misrepresenting quotes. Science, which you claim to admire, does not tolerate poor research.

    • #109046
      scottie
      Participant

      wbla3335 » Sun Jan 15, 2012 5:15 am

      quote :

      As Jack has urged, please clarify why you think that HGT falsifies evolutionary theory

      Please read what I have actually said or have you not bothered to read my response to Jackbean’s question.
      You don’t have to look very far, just 7 lines from the bottom of my last post.

      quote :

      HGT doesn’t disprove any evolutionary process. It disproves the core Darwinian concept of decent from a universal common ancestor.

      Does that sound as if I am claiming HGT is falsifying evolutionary theory?

      It is militating against the core Darwinian view of common ancestry.
      Koonin actually goes further than I have. He includes the

      quote :

      central role of reproductive isolation between species in evolution

      Please argue against what I am actually saying.

      quote :

      Specifically, please provide support that these authors, particularly Koonin, think evolution is bogus. You should thoroughly research something before misrepresenting quotes. Science, which you claim to admire, does not tolerate poor research.

      Once again where have I stated that Koonin thinks evolution is bogus?
      Are you not aware that I also acknowledge that evolution actually happens.
      Change over time is a fact of life.
      It is the Darwinian process of random mutation and speciation that I challenge, and I bring to bear the research of major figures and institutions of science in support.

      So please when it comes to misrepresenting views it would be helpful to follow your own advice.

    • #109050
      wbla3335
      Participant
      quote scottie:

      HGT doesn’t disprove any evolutionary process. It disproves the core Darwinian concept of decent from a universal common ancestor.

      The conjunction of these two sentences belies your level of understanding. Evolution IS descent from common ancestors. You’re suggesting that HGT disproves this. It doesn’t. Are you suggesting that HGT is the dominant means of gene transfer? Are you suggesting that HGT somehow negates the consequences of vertical transfer?

      quote :

      It is the Darwinian process of random mutation and speciation that I challenge, and I bring to bear the research of major figures and institutions of science in support.

      You have done no such thing. You have misunderstood, quoted out of context, and promoted minority views while ignoring the overwhelming evidence that does not support your faith.

    • #109060
      scottie
      Participant

      wbla3335

      quote :

      "scottie wrote:HGT doesn’t disprove any evolutionary process. It disproves the core Darwinian concept of decent from a universal common ancestor."

      The conjunction of these two sentences belies your level of understanding. Evolution IS descent from common ancestors

      (1) Darwinism and neo Darwin or Modern synthesis IS decent from a Universal Common Ancester.(LUCA) not the rather loose description you appear to be trying to slide into.
      Unless, — if you are advancing your own private theory then please clearly state what that theory is so there can be no confusion.

      quote :

      You’re suggesting that HGT disproves this. It doesn’t.

      (2) Doesn’t disprove what? Your private theory or the neo Darwinist belief?
      Koonin’s view is

      quote :

      horizontal gene transfer seems to challenge the traditional, tree-based view of the evolution of life and the core neo-Darwinist belief in the central role of reproductive isolation between species in evolution.

      Is he wrong?
      If so then may I suggest that you inform Koonin of that fact and perhaps demonstrate it by presenting your evidence in support. (so far you are simply making statements

      quote :

      Are you suggesting that HGT is the dominant means of gene transfer?

      No

      quote :

      Are you suggesting that HGT somehow negates the consequences of vertical transfer?

      Again No – vertical transfer is a fact of inheritance. Why would you think I was suggesting that?

      Maybe when I actually get to the point of presenting the evidence relating to HGT that researchers are bringing to light you may understand the subject a little bit more.

      Now finally

      quote :

      "It is the Darwinian process of random mutation and speciation that I challenge, and I bring to bear the research of major figures and institutions of science in support."

      You have done no such thing. You have misunderstood, quoted out of context, and promoted minority views while ignoring the overwhelming evidence that does not support your faith.

      If I have done no such thing. Well then please explain what else you require in the way of evidence.
      For example
      When I refer to NASA’s considered view that I reported in this post
      about14351-180.html
      by scottie » Fri Aug 19, 2011 12:31 pm
      This is a minority view is it?
      Or when I reported on the evidence of no precursor to the ribosome here
      about14351-204.html
      by scottie » Tue Sep 13, 2011 10:05 pm
      This is something being taken out of context is it?
      Or when I reported on the subject of cave animals here
      about14351-384.html
      by scottie » Sun Dec 25, 2011 1:01 pm
      What just another minority view?

      When I reported on isochores here
      about14351-396.html
      scottie » Tue Jan 03, 2012 12:15 pm
      Of course another minority view. Why should anyone pay attention to the NIH?

      If all this evidence is wrong then you should have no trouble in refuting them with your own evidence.
      I don’t understand why you are so reluctant.
      Could the uncomfortable truth be that you are simply unable to.
      That would be an explanation, would it not?

    • #109063
      JackBean
      Participant
      quote scottie:

      quote :

      Are you suggesting that HGT is the dominant means of gene transfer?

      No

      quote :

      Are you suggesting that HGT somehow negates the consequences of vertical transfer?

      Again No – vertical transfer is a fact of inheritance. Why would you think I was suggesting that?

      Because if no, there is no problem. For the vertebrates you can easily make a tree of life with only one ancestor. For previous life it will be little bit harder, since it’s more like bush than tree, but it would lead to one single ancestor again.

    • #109066
      wbla3335
      Participant
      quote scottie:

      Darwinism and neo Darwin or Modern synthesis IS decent from a Universal Common Ancester

      Isn’t that what I said?

      quote :

      Doesn’t disprove what?

      What you were claiming it disproves.

      quote :

      Is he wrong?
      If so then may I suggest that you inform Koonin of that fact

      Koonin knows exactly what he is saying (and why). You don’t.

      quote :

      Maybe when I actually get to the point of presenting the evidence relating to HGT that researchers are bringing to light you may understand the subject a little bit more.

      I’ve been interested in HGT since it first came to light. Do you really think your armchair understanding of anything biological surpasses that of biologists? Didn’t you say you were some sort of engineer? I’m an armchair physicist and would never have the audacity to suggest that I know more than a real physicist. Get real.

      quote :

      I don’t understand why you are so reluctant.

      It’s not my part to educate you. The biologists on this forum enjoy answering legitimate questions, but we are not compelled to cater to deniers. When anti-evolutionists come onto an evolution forum, the onus is on them to convince us, not for us to convince you. You’re not looking for answers. You’re not making much progress here, partly because you’re not presenting a coherent argument, and partly because you interpret your "evidence" through the filter of your faith. Science requires an open mind and a willingness to weigh ALL the evidence.

    • #109070
      scottie
      Participant

      Here is a Primer in HGT
      Now stick with this, it is not coming from an armchair biologist, you will find this journal helpful

      http://www.landesbioscience.com/journal … cle/18776/
      What Nematode genomes tell us about the importance of horizontal gene transfers in the evolutionary history of animals

      Definition

      quote :

      Horizontal gene transfer (HGT) can be defined as the movement of a gene from one donor species to a receiver species by means other than vertical inheritance from a direct common ancestor has been recognized as an important phenomenon in the evolutionary biology of prokaryotes.

      It continues

      quote :

      In eukaryotes, in contrast, the importance of HGT has long been overlooked and its evolutionary significance has been considered to be mostly negligible. However, a series of genome analyses has now shown that HGT not only do probably occur at a higher frequency than originally thought in eukaryotes but recent examples have also shown that they have been subject to natural selection, thus suggesting a significant role in the evolutionary history of the receiver species.

      So what is the mechanism that effects this transfer?
      It continues
      How Were the Genes Transferred in Nematode Genomes?

      quote :

      Both for plant-parasitic and necromenic nematodes, the question of the mechanisms that have allowed successful gene transfer in their genomes is intriguing and remains undetermined. Intuitively, gene transfer in the genome of an animal appears very challenging. Indeed, even if we assume that the gene is transferred in a genomic location compatible with its transcription and translation, several barriers have to be passed before a gene can be integrated in the genome of an animal. Animals have a separate germline and HGT must reach cells in the germline to have a chance to be transmitted to the offspring, otherwise they will remain individual-specific….
      quote :

      Conclusion
      As more animal genomes are being sequenced we can expect new cases of HGT to be reported. Usually, candidate HGT in animal genomes are identified by searching genes that are more similar to bacterial or fungal genes than to genes of closer relatives like other animals. However these approaches will not allow identifying HGT events between different animals.

      So although HGT is being more and more recognised as having occurred in eukaryotes, the mechanism of this gene transfer is undetermined. The way HGT is recognised is by gene similarity.
      The assumption being that this sort of similarity has come about by as yet some unknown evolutionary process.

      So what would any evolutionary process have to take account of?
      Again lets not speculate

      Here is some interesting information of immune system response to gene alterations from the Stanford School of Medicine.
      How does HGT invade a cell without the immune system responding to prevent?

      http://med.stanford.edu/news_releases/2 … quirt.html
      This interesting article on sea squirts shows that Sea squirts only fuse with relatives (genetically similar). It rejects those that are not near relatives.

      So, a reasonable question
      How does HGT take place without immune response, especially in nature?
      Has HGT ever been observed or is it just a hypothesis to explain gene similarity in different species.

      What is research actually revealing?
      Lets go to this paper

      Lateral gene transfer and the nature of bacterial innovation
      http://www2.yale.edu/ochman/Papers/Ochm … re2000.pdf
      Under the subheading

      quote :

      The impact of acquired DNA (page 303)
      Lateral gene transfer provides a venue for bacterial diversification by the reassortment of existing capabilities. Yet, while the emergence of new phenotypic properties through lateral gene transfer furnishes several advantages, it also presents several problems to an organism.
      Newly acquired sequences, especially those conferring traits essential to only a portion of the bacterial life cycle, are most useful when they are appropriately and coordinately regulated with the rest of the genome.
      In Salmonella, the expression of several independently acquired virulence genes is under the control of a single regulatory system – the PhoP/PhoQ two-component system that was already performing essential functions in the genome before the acquisition of these genes
      Although the precise manner by which each of these genes is regulated has yet to be resolved, these findings suggest that the physiological capabilities and adaptation of very divergent bacteria rely on a common set of universally distributed regulatory signals

      HGT therefore has to be a highly regulated process

      So what is PhoP/PhoQ regulation?
      Here is a good description of this regulation
      http://jb.asm.org/content/183/6/1835.full

      quote :

      The Pleiotropic Two-Component Regulatory System PhoP-PhoQ
      Here, I first discuss how the PhoP-PhoQ two-component system responds to environmental cues and interacts with other regulatory systems to integrate multiple signals into a coordinated cellular response and then I describe the PhoP-regulated genes mediating the various PhoP-controlled functions, including virulence.

      The phoPQ operon is autogenously controlled, that is
      Regulation of gene expression is by a product of the gene itself that either inhibits or enhances the gene’s activity.

      A bit more information from
      Proceedings from The National Academy of sciences of the United States

      Autogenous and nonautogenous control of response in a genetic network
      http://www.pnas.org/content/103/34/12718.full

      quote :

      Discussion
      Biomolecular interactions within cells ultimately decide their physiology. This genetic circuitry resembles in many aspects that found in other nonbiological scenarios, and thus control ideas commonly used in these contexts have been incorporated into the understanding of cellular action (30).
      These types of studies are contributing to the discovery of a set of feedback-based regulatory strategies in biological systems and to further confirmation of the possible identification of fundamental design principles of cellular control [e.g., robustness (5, 6), noise tolerance (7), programmed temporal order (8, 11), sign-sensitive dynamics (9, 10), ultrasensitivity (12), optimal performance (13), and implementation-dependent dynamics (14)].

      Pay particular note to the acknowledgement of “fundamental design principles of cellular control”

      Why is this control and regulation needed?

      Well let the Institute of Science in Society answer that question
      http://www.i-sis.org.uk/FSAopenmeeting.php

      Recent Evidence Confirms Risks of Horizontal Gene Transfer

      quote :

      Horizontal gene transfer is one of the most serious, if not the most serious hazard of transgenic technology. I have been drawing our regulators’ attention to it at least since 1996 [1], when there was already sufficient evidence to suggest that transgenic DNA in GM crops and products can spread by being taken up directly by viruses and bacteria as well as plant and animals cells….

      Also check out Gene therapy from Human Genome Project Site
      http://www.ornl.gov/sci/techresources/H … rapy.shtml

      Now if you really want to believe that all this level of cellular control, (and here I have only touched on one little area of cellular organism,) is the product of random and undirected happenings, then your faith in miracles seems to have no bounds.

      This is evidence of design at it’s most exquisite, and even the proceedings from the National Academy of Sciences has no difficulty in openly acknowledging this.

      So please, unless you can demonstrate how your random and undirected happenings can produce all of this, then you have no case to defend.

      Richard Dawkin’s get out of jail phrase is that “science is working on it”
      Is that your answer?
      Oh and by the way he (Dawkins) has recently announced that he has retired from the field of Public understanding of Science. Can’t say I am surprised.

    • #109074
      wbla3335
      Participant

      scottie, how does ANY of this disprove evolution (or common ancestry or whatever)?

    • #109076
      canalon
      Participant

      Or even correct understanding of what is read for that matter.
      You are reading that HGT in Salmonella is under PhoP/PhoQ regulation, when what the paper you are citing is sating that the expression of (some of) the genes that get transfered in plasmids are under that regulation. That is quite different.
      And HGT is extremely widespread and use a plethora of mechanisms that are not all regulated the same way (if at all). But no more than sex does HGT invlid the idea of common descent.

      And by the way, if you aim to discredit Darwin’s explanation of the mechanism of evolution, you are wasting your time. Everybody knows he was wrong in the details (how else, he had no ideas about genes and such), but he is still right in the main idea (changes are generated and selected after generations).

      And as a parting remark, your attacks against what you call philosophy are again underlining your lack of both understanding of science and selfawareness. Philosophy is essential to science, it is the reflection about our practices and how we go on about doing science. There is a lot of useless fluff, but a lot of it is useful. Just like the scientific method that you like to wrap yourself into. It is essentialy a philosophical description of what science is and how it should work.

    • #109092
      scottie
      Participant

      Canalon

      quote :

      You are reading that HGT in Salmonella is under PhoP/PhoQ regulation, when what the paper you are citing is sating that the expression of (some of) the genes that get transfered in plasmids are under that regulation.

      Of course it is an example. I used it to illustrate that HGT has to overcome a highly regulated response to any foreign transfer.
      After all what is the purpose of the immune response system if it is not to protect against foreign ingress.

      quote :

      And HGT is extremely widespread and use a plethora of mechanisms that are not all regulated the same way (if at all).

      I also stated that HGT is recognised only on the concept of similarity. But for it to be valid it has also to explain the mechanism.
      Could you provide an example of a mechanism please. I don’t know of one, maybe there is.
      But please not an assumption, an actual mechanism by which this transfer has been shown to take place?

      quote :

      But no more than sex does HGT invlid the idea of common descent.

      Common decent from what?
      Please at least acknowledge that neo Darwinian theory is based on, not just common decent but on common decent from a Universal common ancestor. That is the foundation pillar of the theory, hence the tree of life concept. The hypothesis of HGT invalidates or at least challenges that concept.
      That is what Koonin is showing.
      As I understand it, you appear to be sliding away from that concept but at the same time arguing (as wbla3335 has) that there is no difference between the two views. There is a big difference.

      Now of course sex produces a progeny from an ancestor but not from a Universal common ancestor.

      We know that Darwin was wrong for the reasons you have given. But the standard theory, with all it’s epicycles, is what I am challenging.

      quote :

      but he is still right in the main idea (changes are generated and selected after generations).

      With respect Patrick that is a very loose statement.
      Changes are generated, but how?
      Is not your view that these are random mutations (changes) to the genome.
      Also
      Can you also be clearer as to how these changes are selected after generations?

      quote :

      Philosophy is essential to science,

      I agree but only within the bounds of what natural processes can demonstrate.
      That is why the scientific method as a philosophical concept has stood the test of time.
      It is also the reason I have, as you put it, wrapped myself into it.

      The problem I have with “Darwinism or neo Darwinism or what is commonly referred to as evolution” is that it is philosophical view that attributes to natural forces that which these forces cannot accomplish, and I have been producing the evidence that demonstrates that point. Hence my often rather boring but I would argue detailed posts.

      Any theory presented in broad terms can appear very persuasive, however it is in the details that it stands or falls.

    • #109093
      JackBean
      Participant

      scottie, there is difference between lineage of genes and individuals. What we usually build from molecular data is gene tree, but does HGT affect the offspring production? I don’t know how about you, but I could build my family tree, ergo I have a common ancestor.

    • #109094
      wbla3335
      Participant

      scottie

      I think part of the problem with your posts is that you have difficulty communicating. You go on and on and on about this or that, but I, at least, have been unable to discern what your core arguments are (other than you think evolution is bogus). You could help us and yourself if you could focus. Maybe your ideas are clear in your head, but they are not in ours. I’ll help by proposing that you complete the following sentence:

      HGT disproves evolution (or common ancestry or whatever) because ________. (Notice the period at the end.)

    • #109110
      scottie
      Participant

      I fully appreciate that there is often a communication problem here.

      Jackbean
      I understand the point you make about lineage and individuals. However the matter of HGT became relevant because when researchers tried to build gene tree lineages they hit a serious problem.
      They started to get different results depending on which gene or indeed protein was being selected.
      The problem was that one of their assumptions was that genes could only be handed down vertically ie from ancestor to offspring as per common decent and species divergence. (The Darwinian principle) the ultimate ancestor being (LUCA) in this bifurcating tree like process

      The other assumption was that similar genes but in different species indicated common ancestry between species. The more similar, the closer the relationship on this bifurcating tree of life
      So the theory was that a gene tree could be constructed showing the relationship between (and ultimately ) all species, thus proving Darwin’s idea, but through molecular investigation.

      The problem that surfaced was that genetic information was found to be very intermixed even across domains.

      Now this was initially showing up among prokaryotes (bacteria and archaebacteria)
      But more recent research is revealing this showing even in eukaryotic life forms, as more animal genomes are sequenced. Evidence of this is the example of the Nematode that I have referred to.

      So this similarity of genetic information has negated the original Darwinian tree.
      What is now emerging is more like a bush or forest. Some even regard a Net to be a more accurate reflection of genetic history.

      So Horizontal Gene Transfer is assumed to be the way in which this mix of genetic information has come about.

      With all this in mind though, the actual mechanism(s) by which any transfer of genetic information between organisms takes place is unknown.

      What is known is that any transfer that does take place must overcome the control and regulatory mechanisms that prevents foreign genetic mixing.
      These controls present a serious challenge to genetic transfer because the controls are specifically intended to prevent such transfers.
      When that does happen it is invariably deleterious to the receiving organism.

      The only mechanisms that I am aware of is that which researchers use in the labs.
      Of course these is not natural but artificial mechanisms

      So wbla3335 coming to your question

      quote :

      HGT disproves evolution (or common ancestry or whatever) because ________. (Notice the period at the end.)

      HGT does not disprove the “evolutionary” ie the change over time, view.

      If such mechanism(s) of this transfer actually exist, as they are assumed to, then it is a serious challenge to the view of common decent from a universal common ancestor. This of course is the Darwinian core concept and it is what Koonin was explaining.
      Koonin does of course assume that mechanisms do in fact exist, we just haven’t discovered them yet.

      Remember though, that it is the similarity of genetic information in different species that has led to the assumption that transfers have taken place.
      I see a more appropriate name for this observation to be Horizontal Gene Similarity as opposed to “Transfer”, unless of course an actual natural mechanism is discovered.

      The design view such as I advocate, would argue that this similarity is evidence of a natural way for a designer to reuse different functions already designed, in different species, with slight modifications to suit the particular circumstances.
      GM crops is a practical example of how this is achieved.

      Gene therapy is also another design applied way to rectify faulty mechanisms, but with significantly high risks to organs when natural immune responses are suppressed to allow these modifications.

      Gene similarity across even distant species challenges the core Darwinian principle of common ancestry.
      If there is a natural mechanism for HGT then certainly the core pillar of universal common decent is refuted.
      However it does not refute evolution (i.e change over time) as such.
      I hope this clears up any misunderstandings.

    • #109111
      wbla3335
      Participant
      quote scottie:

      Gene similarity across even distant species challenges the core Darwinian principle of common ancestry.
      If there is a natural mechanism for HGT then certainly the core pillar of universal common decent is refuted.

      Are you saying that HGT discredits phylogenies derived from vertical transmission? If so, you are really grasping at straws. Do you really think that an omnipotent creator would need to reuse gene sequences here and there? Why bother to create a huge diversity of gene sequences in a huge diversity of creatures and then get lazy with a relative few? Saying that HGT refutes common descent is like saying that the similarity of a few gene sequences in diverse organisms refutes the existence of an omnipotent creator.

    • #109170
      scottie
      Participant

      wbla3335
      Sorry for the delay. Life beyond this forum exists. 🙂
      Now I do wish you would respond to what I actually write.
      This is what I wrote

      quote :

      However the matter of HGT became relevant because when researchers tried to build gene tree lineages they hit a serious problem.
      They started to get different results depending on which gene or indeed protein was being selected.

      Is it your claim that that these problems are not manifest?

      This hypothesis was introduced, essentially by Gogarten and Woese, to explain these very difficulties.

      If they didn’t exist, HGT would not have been a necessary hypothesis
      So is there vertical lineage?
      Yes, within species.
      Are there problems in determining what the vertical lineage actually is beyond species?
      Again Yes.
      Why?
      Because when researchers try to establish these lineages they get different results depending on which gene or protein they use.
      Hence the concept of HGT was formulated to explain away these difficulties.

      So is the hypothesis of decent from a common universal ancester correct?

      Well it can only be regarded as correct if it can be demonstrated to be so.
      Molecular investigation was the mechanism that was expected to do just that.
      Although very informative it has not shown that vertical decent from a Universal common ancestor (i.e. across species) is correct.

      quote :

      Do you really think that an omnipotent creator would need to reuse gene sequences here and there?

      Why not?
      This principle is sound in design theory.
      Designers follow this principle every day in their design works.
      How many different versions of the wheel do you see in designs today and indeed throughout history.
      What about sub routines in computer programming?
      Many of these routines are called upon variously and in different programs.
      The very computer application you are using to communicate your views on this forum is replete with routines used commonly.

      quote :

      Saying that HGT refutes common descent is like saying that the similarity of a few gene sequences in diverse organisms refutes the existence of an omnipotent creator

      I don’t understand what it is you are trying to say.

      What I will do however is ask you a simple question.

      What challenges have to be overcome for HGT to actually occur in nature.
      In other words, for DNA to be taken up from another organism, what stages of transfer would be required from both donor and recipient.
      You are a biologist so you should have no difficulty in explaining to this forum what those stages would be.
      Would you do that, please.

      If you are unable to then I would be quite happy to do so.

    • #109173
      JackBean
      Participant
      quote :

      Are there problems in determining what the vertical lineage actually is beyond species?
      Again Yes.
      Why?
      Because when researchers try to establish these lineages they get different results depending on which gene or protein they use.
      Hence the concept of HGT was formulated to explain away these difficulties.

      That’s why I was talking about the difference in gene and individual trees. You should know, that even creation of the gene trees is little magic simply because we do not know when and what changes happened. We are usually going for least changes, but there is a chance that some mutation occurred and then other, reverting one occurred again.
      But since we are able to build trees of individuals, we would be theoretically trace our ancestors down to LUCA.

    • #109190
      wbla3335
      Participant
      quote scottie:

      However the matter of HGT became relevant because when researchers tried to build gene tree lineages they hit a serious problem.
      They started to get different results depending on which gene or indeed protein was being selected.

      This happens without HGT.

      quote :

      Is it your claim that that these problems are not manifest?

      No.

      quote :

      This hypothesis was introduced, essentially by Gogarten and Woese, to explain these very difficulties.

      If they didn’t exist, HGT would not have been a necessary hypothesis

      HGT was known long before anyone tried to build trees from sequences. HGT is only one of the problems phylogeneticists face.

      quote :

      Because when researchers try to establish these lineages they get different results depending on which gene or protein they use.

      This happens without HGT sequences. See above. Phylogenetics is a complicated endeavour that requires a very careful selection of sequences.

      quote :

      Hence the concept of HGT was formulated to explain away these difficulties.

      Still wrong. HGT was formulated to explain the existence of identical or nearly identical sequences in organisms too diverse for the sequences to have got there vertically. "Explaining away" is your interpretation.

      quote :

      Do you really think that an omnipotent creator would need to reuse gene sequences here and there?
      Why not?

      Agree. Since you are designing your designer, you can give it whatever properties you wish.

      quote :

      I don’t understand what it is you are trying to say.

      The occurrence of identical or nearly identical sequences in a diverse array of organisms clearly falsifies creation.

      quote :

      What challenges have to be overcome for HGT to actually occur in nature.
      In other words, for DNA to be taken up from another organism, what stages of transfer would be required from both donor and recipient.
      You are a biologist so you should have no difficulty in explaining to this forum what those stages would be.

      I’m not unable, but as I’ve said, I’m not here to educate you. Your postings aren’t worth so much of my time.

    • #109250
      scottie
      Participant

      wbla3335

      quote :

      I’m not unable, but as I’ve said, I’m not here to educate you. Your postings aren’t worth so much of my time.

      I take it then that you don’t actually understand the intricacies of the HGT proposal OR you do understand, but can’t bring yourself to openly acknowledge what prevent this as a viable explanation.
      So allow me to set out the problems and I will do that next.

      Jackbean
      I think we are getting onto the same page here.
      As you say even the building of gene trees is a little magic because we don’t know when and what changes happened.
      How true.
      If we don’t know or even understand what those basic fundamentals are, how can we then say these evolutionary forces are matters of fact.
      I acknowledge of course that you are not saying that but others are doing just that.

      quote :

      But since we are able to build trees of individuals, we would be theoretically trace our ancestors down to LUCA.

      But these gene trees can only be established within species.
      To theoretically trace back to LUCA HGT must be invoked.
      The question is how valid a hypothesis is HGT?

      That is what wbla3335 is having difficulty in coming to terms with.

    • #109251
      scottie
      Participant

      Here are some of the stages whereby a cell can take in foreign DNA.
      1 There has to be DNA in the immediate environment.
      2 The host cell must be capable of receiving this DNA. In other words it
      must be competent, which begs the question, what is competence?
      3 For any interaction between the cell and free DNA, specific sequences
      and receptors are involved..
      4 How is the entry of DNA through the outer cell membrane (periplasmic
      space) and then, in the case of eukaryotic cells, the nuclear
      (cytoplasmic) membrane processed.
      5 This foreign DNA then has to be integrated into the chromosome so that
      it can be functionally expressed into cell operation.
      Apart from the first all these stages are common to any type of gene transfer.

      So by simply enumerating the stages we begin to get an idea of what any natural and unguided process has to produce.

      But of course it becomes much more complicated when we start to investigate each stage process. Lets just touch on some of the detail.

      Stage 1 It is assumed that DNA in varying concentrations is present in almost any environment, due to spontaneous cell lysis (breakdown), digestion etc.

      Stage 2. Competence
      This is a specific physical state of bacterial cells that allows nucleic acids to bind to the cell surface and be taken up by the host.
      Studies have shown that are different requirements for different lengths of this free DNA, also for different states of DNA, i.e ssdna (single stranded) dsdna (double stranded) If you look up any review on this matter of competence you will invariable find such expressions as “unclear” “not known” even “mysterious”.
      Some research suggests that only about 1% of bacterial species are naturally capable of taking up DNA under lab conditions.

      Stage 3 requires specific molecules to be in place. How? from where?

      Stage 4 So how does this transfer occur. Well the simple answer is we don’t know.
      What we do know however is what kinetic studies have shown and that is, the process of transfer through just the nuclear(cytoplasmic)membrane occurs surprisingly, quite rapidly. Surprising because this is a very highly controlled and regulated process with very defined energy requirements.

      Stage 5 This DNA has then to be functionally integrated into the host chromosome, again another highly controlled and regulated process. Remember the host cell naturally guards against foreign infestation.

      The details of each stage would require it’s own essay in explanation apart from all the unknowns.
      So just a very brief overview of a process reveals what is naturally possible and what is not.
      HGT is a hypothesis that has been posited to try and explain away the incongruities between the Darwinian species tree founded on LUCA and what gene trees are revealing.
      But as we can see from just this simple overview even this process cannot be accommodated within the framework of natural and undirected processes.

    • #109259
      wbla3335
      Participant

      Just a few things for you to ponder and look into, scottie.

      Do you consider HGT by your proposed "steps" impossible or unlikely?
      Research other proposed mechanisms.
      Investigate the difference between gene trees and species trees.

    • #109268
      scottie
      Participant

      wbla3335
      Oh dear, I am going to try and be patent

      quote :

      Do you consider HGT by your proposed “steps” impossible or unlikely?

      These aren’t my proposed steps. These are the steps required to effect gene transfer. There is clearly a gap in your understanding of the process.

      quote :

      Do you consider HGT by your proposed “steps” impossible or unlikely?

      HGT is a reality, in the laboratory of researchers that design the methodology required. GM in crops is one such process.
      In nature it is assumed because of the similarity of gene sequences in different species.
      Do please try and at least understand the subject you are cat calling about.

      quote :

      Research other proposed mechanisms.

      What other mechanisms?
      Or are you going to revert to your “ It is not my job to educate you” mode 🙂

      quote :

      Investigate the difference between gene trees and species trees.

      Are you not aware that the molecular investigation of genes was intended to support the Darwinian species tree concept of vertical inheritance that provided speciation?
      Therefore the gene tree was supposed to confirm the Darwinian tree of life concept.
      It hasn’t proved to be so and that is why the concept of HGT has been proposed.
      Now what is it you seem to be finding so hard to grasp?
      You are clearly out of your depth here, my advice is to stop digging, the hole is getting rather large.

    • #109269
      wbla3335
      Participant
      quote scottie:

      You are clearly out of your depth here

      An armchair biologist/creationist suggesting that an evolutionary biologist is out of his depth in a discussion of evolution? Can you consider the possibility it might be the other way around? Just maybe?

    • #109277
      ughaibu
      Participant
      quote scottie:

      So is the hypothesis of decent from a common universal ancester correct?

      Well it can only be regarded as correct if it can be demonstrated to be so.

      You seem to be equivocating over technical and colloquial definitions of "hypothesis". Evolutionary theories which posit a universal common ancestor will allow the generation of hypotheses which either will or won’t adequately predict the probability of making certain observations. However, such theories do not entail ontological commitment to the models which are posited within them, predictive accuracy is independent of ontological correspondence. So, conjecturing about the historical fact or otherwise of a universal common ancestor isn’t important for evolutionary theory, and in any case, is not a question which can be settled by observation.

    • #109280
      Anonymous
      Participant

      What about he endosymbiotic theory? You could look into that.

    • #109301
      scottie
      Participant

      biostudent12 » Sun Jan 29, 2012 12:17 pm

      quote :

      What about he endosymbiotic theory? You could look into that.

      Thanks for your suggestion.
      Yes I have looked into this theory in some detail and have covered it before.
      However here is a good explanation of the theory.
      http://users.rcn.com/jkimball.ma.ultran … iosis.html
      This is the theory that eukaryotic cells arose as a result of one prokaryotic cell engulfing (without digestion) another cell. The engulfed cell becomes the mitochondria or chloroplasts of the new cell. These have their own circular genome carry out transcription and translation and replicate independently of the host cell by binary division, similar to bacteria.

      There are several problems with it.
      For example the mitochondria’s genetic code is at variance with the standard DNA code. The codon UGA is a stop codon in the standard code, but encodes for Tryptophan in mitochondria. ( I have covered this before)
      This means that the genes of the ingested prokaryote would have had to have been re-coded (somehow) on their way into becoming the nucleus of the emerged eukaryote. How does that happen? Remember the two prokaryotes have the same DNA code to begin. There are a lot more details I can elaborate on, but I hope you get the point.

      Then there is another problem. The mitochondrial protein is tagged with an extra length of polypeptide to ensure that is recognised by the cell as a product of the mitochondria.
      What unguided and random processes can produce a different symbolic meaning to the code and also know of a need to identify the origin of a protein.

      Any naturalistic theory cannot answer these questions.
      But it gets worse.
      There is the additional problem of energy requirements.

      In a review article by Nick Lane and William Martin published in Nature in Oct 2010
      http://www.nature.com/nature/journal/v4 … 09486.html
      This problem is addressed.
      The energetics of genome complexity
      The abstract reads

      quote :

      All complex life is composed of eukaryotic (nucleated) cells. The eukaryotic cell arose from prokaryotes just once in four billion years, and otherwise prokaryotes show no tendency to evolve greater complexity. Why not? Prokaryotic genome size is constrained by bioenergetics. The endosymbiosis that gave rise to mitochondria restructured the distribution of DNA in relation to bioenergetic membranes, permitting a remarkable 200,000-fold expansion in the number of genes expressed. This vast leap in genomic capacity was strictly dependent on mitochondrial power, and prerequisite to eukaryote complexity: the key innovation en route to multicellular life.

      The energy requirement in processing the eukaryotic DNA is far greater that what is available by a bacterial cell.
      The ATP requirement by necessity, requires the presence of mitochondria.
      Do you see a chicken and egg situation here?

      The number of mitochondria varies according to the type of cell, between one and 10,000 with an average of about 200.
      The human liver has over 1,000 mitochondria.
      Now ask yourself just one question
      How does the mitochrondria know how many divisions are necessary for each type of cell?

      Why do you think that these reviews postulate that this has happened only once?
      Simply because the odds are so remote that a one off event is the only one that can even be put forward as hypothesis.
      None of these questions can be answered except as a result of design requirements.

    • #109315
      wbla3335
      Participant
      quote scottie:

      Any naturalistic theory cannot answer these questions.
      quote :

      None of these questions can be answered except as a result of design requirements.

      I guess this is why you can’t reason like a scientist. You must really, really want to believe in that god of yours. I’m curious why.

    • #109330
      scottie
      Participant

      wbla3335

      This is all so sad.
      You are sounding more and more like Richard Dawkins.
      That poor fellow has had to retire from educating the public on science matters, so like any faithful disciple you appear to be doing the same. 🙂
      And why not?

    • #109338
      wbla3335
      Participant

      scottie,

      I’m a fan of Dawkins the biologist, not Dawkins the atheist. But the guy’s 70 years old – I don’t think he was forced to retire, as you imply. What’s sad is your pretension to understanding things you don’t. Better people than you have been trying longer than you to debunk evolution, without success. No one has ever come to a belief in a god by a rational analysis of the available evidence. That’s no proof one does not exist, just unlikely to. Believers have either been indoctrinated from birth or have a need to believe in something other than the natural world. I don’t mind you believing in whatever you wish, and I don’t mind your efforts to justify your belief (although you DO need to research more deeply before heading down blind alleys), but you really must stop making silly statements like those I have recently quoted.

    • #109344
      Nick7
      Participant
      quote wbla3335:

      That’s no proof one does not exist, just unlikely to..

      Likely / unlikely…. You are quantifying something that is, as it stands, unquantifiable, cause we lack knowledge, enough evidence and even capacity to gather enough evidence. At the same time you offer little to debunk Scottie’s statements, cause you don’t want to waste your time on Scottie-the-engineer. That’s understandable, but Scottie is a conduit. All these ideas are most likely (let Scottie correct me) are gathered from your peers. For instance, Brown Norway rat reasoning from page 34, as far as I know, was first made by your colleague ( http://www.richardsternberg.com/biography.php ). Just like all the other arguments presented can be traced to biologists, geneticists, …. Are those people aware that their conclusions point at something that is unlikely and it’s silly to even waste time on it?

    • #109345
      ughaibu
      Participant
      quote Nick7:

      quote wbla3335:

      That’s no proof one does not exist, just unlikely to..

      Are those people aware that their conclusions point at something that is unlikely and it’s silly to even waste time on it?

      Gods are fictional characters and I think that it’s highly unlikely that the conclusions of Wbla3335’s "peers", regardless of what you mean by that, suggest the reality of those fictional characters.
      1) if "their conclusions point at something that is unlikely" is not intended to mean ‘their results point to the conclusion that real gods exist’, please clearly explicate your meaning.
      2) if "their conclusions point at something that is unlikely" is intended to mean ‘their results point to the conclusion that real gods exist’, please clearly present an argument in support of that contention.

    • #109347
      wbla3335
      Participant

      Nick. Absolute knowledge is a rare animal. The best we mortals can do is to deem something more or less likely than something else. As ughhaibu alludes to, the findings of science often differ from the interpretations of those findings, particularly unqualified and prejudged interpretations.

    • #109367
      Nick7
      Participant
      quote ughaibu:

      Gods are fictional characters.

      I know… 😕 . I’ve read it somewhere already… Gods are fictional characters… Religion is the opium of the people….. Yeh, I believe this stuff was in my soviet 4th grade “History of the Ancient World” text book. But I have kinda already deviated from a black’n’white perception of controversial issues of that nature by now.

      quote ughaibu:

      I think that it’s highly unlikely that the conclusions of Wbla3335’s “peers”, regardless of what you mean by that, suggest the reality of those fictional characters.

      Well, the guy I mentioned above is an evolutionary biologist with Ph.D. in Molecular Evolution and Ph.D. in Theoretical Biology, which would (I assume) make him Wbla335’s peer. If you open the link above and read his one-paragraph introduction called “My approach to the study of biology”, you will see that, yes, his conclusions (conclusion / opinion / way of thinking…. Whatever you wanna call it) suggest a possible “reality of those fictional characters” in one form or another. That’s a matter of his opinion of course, but judging by his credentials, that opinion is worthy of consideration.

    • #109368
      Nick7
      Participant
      quote wbla3335:

      …findings of science often differ from the interpretations of those findings, particularly unqualified and prejudged interpretations.

      “That’s no proof one does not exist, just unlikely to….. have a need to believe in something other than the natural world (c)
      all this stuff is also the interpretation. If one is a conscious character in, say, a computer simulation, one cannot possibly objectively and conclusively evaluate through rational thinking how likely or unlikely it is that the reality one exists in is designed or not designed. All one can do is to study the laws governing one’s existence in all their enormous complexity and structure. Anything more than that will require breaking the boundaries of space and time, stepping out of the computer simulation and evaluating the situation from aside… something one can’t do (as it stands, at least). Therefore, allocating the role of the designer to “the natural world” also seems to be quite subjective to me, and I don’t see how one can rationally quantify it (likely or unlikely…)
      P.s. Personally, I don’t care about naturalistic or non-naturalistic origins of life, universe, etc. I care about the truth (whatever that ends up to be), which assumes providing the podium to the people of diverse opinions, provided they have brains, decent level of education & provided that they do care in this life about something higher than who exactly currently Kim Kardashian sleeps with. Now Scottie is not an evolutionary biologist, agree, but it definitely doesn’t seem like he just hatched into a civilized world from the wilderness of the Polynesian forest either…. And he usually provides links to the opinions of the more-than-qualified individuals. And when he doesn’t, I’m pretty sure you can trace them.

    • #109373
      wbla3335
      Participant
      quote Nick7:

      Therefore, allocating the role of the designer to “the natural world” also seems to be quite subjective to me, and I don’t see how one can rationally quantify it (likely or unlikely…)

      Everything that goes on in heads is subjective, but some of it can be based on evidence. In the absence of evidence for the supernatural, some of us consider the natural to be more likely. Some of us don’t.

      quote :

      And he usually provides links to the opinions of the more-than-qualified individuals.

      He provides links to studies. The opinions he gives are his own. The authors of the studies are not claiming the falsification of evolution nor the existence of a designer.

    • #109379
      ughaibu
      Participant
      quote Nick7:

      That’s a matter of his opinion of course. . . .

      Does this mean that there’s no argument?

      quote Nick7:

      . . . . but judging by his credentials, that opinion is worthy of consideration.

      Not at all. Either he has an argument or he hasn’t.

    • #109423
      scottie
      Participant

      wbla3335
      Well now you appear to have said it all

      quote :

      I’m a fan of Dawkins the biologist, not Dawkins the atheist. But the guy’s 70 years old – I don’t think he was forced to retire, as you imply

      Perhaps another primer, this time for a fan of Richard Dawkins, is in order.

      Education DPhil, MA
      Occupation Ethologist (The scientific study of animal behavior, especially as it occurs in a natural environment )

      Dawkins studied zoology under Niko Tinbergen, the Dutch Nobel prize-winning ethologist. Tinbergen had already outlined his idea that plants and animals could be described as survival machines for genes.

      He was awarded the Michael Faraday Prize for "excellence in communicating science to UK audiences".

      Also the Kistler Prize in recognition for original contributions "to the understanding of the connection between human heredity and human society.

      Has he published any peer reviewed papers on evolutionary biology?
      I have searched and cannot find any, perhaps you could help here as you regard him as a biologist.

      He has written several books and had some ideas on biological evolution.
      His selfish gene concept (not peer reviewed of course) has been shown to be wrong.

      He certainly is an outspoken atheist and a prominent critic of religion.

      So as you are a fan of him as a biologist, please inform this forum (not me personally as I am clearly not deserving of your educational prowess 🙂 ) what contribution has he made to biology?.
      Now you say you are not a fan of him as an atheist.
      Well what else is he known for?
      Now as Nick7 states

      quote :

      At the same time you offer little to debunk Scottie’s statements,

      I think Nick7 is being kind to you.
      You have offered nothing to refute my statements except continually sliding into “god speak” as some sort of authority in the name of science.
      Nick7 is also right when he says that I have only cited references from the peer reviewed evolutionary publications.

      I am though, more cautious than him in regarding them as your peers as you have not demonstrated any willingness to convey exactly what evidence you rely on to buttress your apparent atheism. All that has emanated from you is a philosophical rant.
      But where is the science?
      I’m afraid the evidence shows you as a fan of Dawkins the atheist, not Dawkins the biologist.
      I see no evidence that he is/was a biologist, even though the poor fellow is now 70 years old, a good age though, I’ll have you know. 🙂
      However he doesn’t seem to have benefited much from maturity.

      I would advise not to go down his path, unless you wish to be regarded as an embarrassment to the scientific community and as Michael Ruse (philosopher of biology, aged 72 currently at Forida State University) describes as, “pig ignorant”. 🙂

    • #109431
      wbla3335
      Participant
      quote scottie:

      But where is the science?

      None of this is about the science, scottie. I doubt that any amount of science will prevent you from filtering everything through your faith. We’ve tried to explain to you how science works, but you don’t seem to be catching on. Not much I can do about that, apparently.

      It sounds like you have an issue with Dawkins.

    • #109577
      scottie
      Participant

      I have come across an article in New Scientist which bears on the subject of Natural Selection.
      another fundamental pillar of darwinian evolution.

      You will find the article here
      http://www.newscientist.com/article/dn9 … rming.html

      The actual paper is from Science and is here
      http://www.sciencemag.org/content/313/5794/1773
      entitled
      Global Genetic Change Tracks Global Climate Warming in Drosophila subobscura

      Ok

      The researchers conclude that populations of fruit flies on three separate continents have independently evolved identical gene changes within just two decades, apparently to cope with global warming.

      quote :

      What we’re showing is that global warming is leaving its imprint on genes,” says Raymond Huey at the University of Washington in Seattle, US, who made the discovery with colleagues. “For this to happen in such a short time-frame in so many parts of the world is rather disturbing, he says

      The article goes on

      quote :

      These changes, called inversions – constituting a flip of the order of DNA sections – tally with latitude and, by implication, with ambient temperatures.

      So these inversions are proportional to average temperatures. This of course means that random mutations are clearly not involved and random mutations is a key driving force in Darwinian evolution.

      Furthermore, since there is this direct connection between temperature (environmental pressure)
      and the amount of this inversion (the researchers are connecting this with global warming,) how does Natural selection fit this data?
      Natural selection as we know, is the simple result of variation, differential reproduction, and heredity — it is mindless and mechanistic. It has no goals; it’s not striving to produce "progress" or a balanced ecosystem.

      This is evidently a programmed response to climate (temperature) change.
      Once again we see the darwinian process failing to account for the data.

    • #109583
      AstraSequi
      Participant
      quote scottie:

      So these inversions are proportional to average temperatures. This of course means that random mutations are clearly not involved and random mutations is a key driving force in Darwinian evolution.

      Furthermore, since there is this direct connection between temperature (environmental pressure)
      and the amount of this inversion (the researchers are connecting this with global warming,) how does Natural selection fit this data?

      Maybe the mutations are common enough that they happen all the time?

      Or maybe the mutation occurred once or twice and then spread through the population by interbreeding, with the final frequencies indicating the selective advantage in each particular environment.

      Or maybe the mutation was already at a low frequency in the population (say, 1%), and was neutral until the recent changes.

      quote :

      Natural selection as we know, is the simple result of variation, differential reproduction, and heredity — it is mindless and mechanistic. It has no goals; it’s not striving to produce “progress” or a balanced ecosystem.

      It is an optimization process. It has no long-term goal, but it most certainly does have a short-term one, for each individual generation – and that is to maximize reproductive success.

      quote :

      This is evidently a programmed response to climate (temperature) change.

      Then you should expect that the same amount of temperature change should promote the same amount of mutations. If you look at figure 2 in the paper you cited, this is not the case. Unless the programmed response you are suggesting has some randomness in it. 🙂

    • #109594
      wbla3335
      Participant

      Your beliefs, scottie, are shared by very few people in this world, and you may want to ask yourself why that is. There are lots of theists, fewer deists, even fewer deists who believe that their deity tinkers with its creation, and even fewer deists who believe that their deity micromanages its creation. Your efforts to find support for your beliefs in the findings of science are futile. The only support you’re finding is in your interpretations, which are not the result of an open or rational mind.

      Concerning your latest effort, I don’t have access to the original article, but from what you have provided, i can find no claim that the same inversions originated independently in the different populations (only that the frequencies of the inversions in the different populations are the same). Does the original article make the claim of independent origin?

    • #109599
      AstraSequi
      Participant
      quote wbla3335:

      Does the original article make the claim of independent origin?

      No – in fact, the populations discussed in the paper share very recent common ancestry (the North and South American populations were founded from the Old World populations within the last 35 years), and the inversions have been known about as pre-existing polymorphisms in various Drosophila species for nearly that long.

    • #109600
      wbla3335
      Participant
      quote AstraSequi:

      No – in fact, the populations discussed in the paper share very recent common ancestry (the North and South American populations were founded from the Old World populations within the last 35 years), and the inversions have been known about as pre-existing polymorphisms in various Drosophila species for nearly that long.

      Thanks Astra. So the "independently evolved identical gene changes" are just shifts in frequencies resulting from selection.

    • #109612
      scottie
      Participant

      AstraSequi

      quote :

      Maybe the mutations are common enough that they happen all the time?

      Or maybe the mutation occurred once or twice and then spread through the population by interbreeding, with the final frequencies indicating the selective advantage in each particular environment. 

      Or maybe the mutation was already at a low frequency in the population (say, 1%), and was neutral until the recent changes. 

      Quite a few maybes here.
      What then would be your favoured maybe? 🙂

      (Now I stated that)
      Natural selection as we know, is the simple result of variation, differential reproduction, and heredity — it is mindless and mechanistic. It has no goals; it’s not striving to produce "progress" or a balanced ecosystem.

      Your response

      quote :

      It is an optimization process. It has no long-term goal, but it most certainly does have a short-term one, for each individual generation – and that is to maximize reproductive success. 

      Actually my description of Natural Selection is a direct quote from the NIH and University of California credited teaching site.
      http://evolution.berkeley.edu/evolibrary/article/evo_32

      If you have a different view of NS then may I suggest you correct this august body as it does appear to disagree with your understanding. I am sure they will consider your amendment seriously.

      quote :

      Then you should expect that the same amount of temperature change should promote the same amount of mutations. If you look at figure 2 in the paper you cited, this is not the case. Unless the programmed response you are suggesting has some randomness in it. 

      Firstly please notice that the concluding reference to NS by the above referenced site states very clearly

      quote :

       Natural selection is NOT random!

      Now back to the paper I cited
      It recognises that 4 of the 26 data sets were problematic, however just note their response to comments on this matter
      http://www.sciencemag.org/content/315/5818/1497.2.full

      quote :

      Finally, with regard to our own study, 4 of 26 samples are indeed problematic, but our original conclusions hold when those samples are excluded. We stand by our original conclusion that global genetic change in D. subobscura is tracking global warming and is not a sampling artifact.

      The authors were responding to comments from researchers with more knowledge on this matter that either you or I, so in the absence of a further questioning I am happy the accept that they have responded with credibility.

      So I hold to my statement that, since this genetic change is tracking global warming it is therefore evidently a programmed response to climate (temperature) change.

      Why else would Dr Huey find this data disturbing?
      His words

      quote :

      For this to happen in such a short time-frame in so many parts of the world is rather disturbing
    • #109615
      JackBean
      Participant

      scottie, you get obviously confused mutations and natural selections. Mutations ARE random, the selection is NOT.

    • #109626
      AstraSequi
      Participant
      quote scottie:

      quote :

      Maybe the mutations are common enough that they happen all the time?

      Or maybe the mutation occurred once or twice and then spread through the population by interbreeding, with the final frequencies indicating the selective advantage in each particular environment. 

      Or maybe the mutation was already at a low frequency in the population (say, 1%), and was neutral until the recent changes. 

      Quite a few maybes here.
      What then would be your favoured maybe? 🙂

      …It doesn’t matter. You said that the only possible conclusion was that it was a programmed response, and I gave you three possible ways in which it might not be. If you want to maintain your conclusion, then you have to show that all of these are incorrect, not just one.

      That being said, I think you should be able to interpret based on the information in my last post which one is probably the most likely.

      quote :

      Natural selection as we know, is the simple result of variation, differential reproduction, and heredity — it is mindless and mechanistic. It has no goals; it’s not striving to produce “progress” or a balanced ecosystem.

      Actually my description of Natural Selection is a direct quote from the NIH and University of California credited teaching site.
      http://evolution.berkeley.edu/evolibrary/article/evo_32

      I apologize – I made an equivocation fallacy over the word "goal," with a meaning that I think is incorrect anyways. Always admit your errors. 🙂

      The point I was trying to make was that if you apply the same environmental stress to different populations of the same species, it is expected that they will probably change in similar ways. The change is still directional, and will be in the same direction every generation.

      Reproductive success is the criterion that allows for natural selection, and under selective pressure each generation changes in response to this criterion. My use of the word "goal" was meant to refer to the animals themselves, for whom reproductive success is indeed the goal, and who can take action towards that goal. (Though to be strict I suppose we should only use the word for those organisms with neural processing ability.)

      Also, it’s generally considered good form to list a source when you quote it word-for-word.

      quote :

      Firstly please notice that the concluding reference to NS by the above referenced site states very clearly

      quote :

       Natural selection is NOT random!

      As far as I can tell, the argument in your above post was that natural selection was random, and thus could not result in evolution – or at least, reproducible evolution. If this is the case, please decide what your position is. 🙂

      Natural selection takes initial randomness, in the form of mutations, and eliminates all the randomness that does not fall "in the right direction," so to speak. Refer to Jack’s previous post.

      quote :

      Now back to the paper I cited
      It recognises that 4 of the 26 data sets were problematic, however just note their response to comments on this matter…[“We stand by our original conclusion that global genetic change in D. subobscura is tracking global warming and is not a sampling artifact.”]

      I never said that there was anything wrong with their data. I said that their data do not support your assertion that the
      response must be "programmed."

      As I said above: if you have a programmed response,

      quote :

      then you should expect that the same amount of temperature change should promote the same amount of mutations. If you look at figure 2 in the paper you cited, this is not the case.

      It is not necessary to look at the four outliers to reach this conclusion. The amount of change is quite variable even among populations that experienced the same temperature difference.

      In the most charitable interpretation I can think of, I suppose it is possible to make some assumptions and then say that their data is consistent with a completely deterministic model. However, you cannot say that it is evidence for such a model against natural selection, because natural selection can account for the same results quite well, and without the extra assumptions.

      quote :

      So I hold to my statement that, since this genetic change is tracking global warming it is therefore evidently a programmed response to climate (temperature) change.

      Why else would Dr Huey find this data disturbing?

      Are you sure you can’t think of another reason why someone would be disturbed by the observation that climate change is causing animals to undergo dramatic genetic changes?

    • #109658
      scottie
      Participant

      Jackbean

      quote :

      scottie, you get obviously confused mutations and natural selections. Mutations ARE random, the selection is NOT

      .

      No, I am not confused. I have never stated that NS is random. The mutations are random on which NS is hypothesied to filter. This has always been my understanding of darwinian theory.

      I quoted Berkeley education to correct AstraSequi and of course he has acknowledged that.

      AstraSequi

      Firstly may I thank you for engaging in the science of the subject. It does make a pleasant change and of course challenges thinking processes, which is what good discussions are all about.

      Ok having put on my thinking cap let me respond.

      quote :

      …It doesn’t matter. You said that the only possible conclusion was that it was a programmed response, and I gave you three possible ways in which it might not be. If you want to maintain your conclusion, then you have to show that all of these are incorrect, not just one. 

      Sorry but I said

      quote :

      This is evidently a programmed response to climate (temperature) change.

      You quoted me correctly the first time so I don’t understand why you misquote me now.

      I was stating my considered view based on the data evidence.

      I don’t see how your three “maybe” scenarios answer this question.
      Please note that three separate populations on three different continents developed these same inversions and in an “evolutionary” short space of time.
      How this can be the result of random mutations, which according to darwinian theory they would have to be, unless of course one is happy to play with unlikely statistics.

      Natural Selection is not a force but simply the naturally selected result of random forces.
      The driving force in darwinian theory is the random mutations that allow nature to select from.

      So when you say

      quote :

      The point I was trying to make was that if you apply the same environmental stress to different populations of the same species, it is expected that they will probably change in similar ways. The change is still directional, and will be in the same direction every generation. 

      1) The enviromental stress in three different continents are not the same. What the
      researchers noted was that the climate/latitude was the common factor. That is why
      they made the link with global warming.
      2) According to the theory, the mutations upon which this process rests is Random.
      To expect, as you suggest that changes will probably be in similar ways, is to support
      my view that the change is not random. You can’t have it both ways.
      Either change is random or it is not.
      Please note what another researcher stated which is quoted in the New Scientist.

      quote :

      Camille Parmesan at the University of Texas in Austin, US, who has carried out similar research, says these new findings are a warning that species may only have limited capacity within their own genomes to adapt to climate change.

      If the capacity for change is limited as this researcher warns, then what happens to the theory?
      After all climate has always been on the change throughout life’s history.

      quote :

      Are you sure you can’t think of another reason why someone would be disturbed by the observation that climate change is causing animals to undergo dramatic genetic changes?

      Well actually I cannot think of any reason why Dr Huey would be disturbed, other than this change does not sit well with evolutionary theory.

      The basis of darwinian theory is adaptation to different environments. Species change is the product of random (unguided with no goal) mutations with nature selecting any functional changes that present themselves.
      In other words the functional variation is already there for nature to select.
      If the change is dramatic (as you are suggesting) then new species would be expected to arise.
      Why would that be disturbing?
      Surely this is the natural way, according to the theory.

      No, the reason it is disturbing is because this data does not sit within evolutionary theory.

      This of course raises another question.

      What evidence is there for Speciation through Natural Selection?
      It is after all the corner stone of evolutionary theory.
      Darwin’s own words
      http://www.jstor.org/pss/187407 (please note my good form in naming my source :))

      quote :

      “When we decend to details, we can prove that no one species has changed [ i.e. we cannot prove that a single species has changed]; nor can we prove that the supposed changes are beneficial, which is the groundwork of the theory. Nor can we explain why some species have changed and others have not. ( Darwin 919, 2:210)

      Has this situation changed since Darwin’s day?
      Can someone help with some evidence.

      Lets try and make the question a little easier.

      What evidence is there that random mutations and natural selection can produce new functional biological information.

    • #109660
      wbla3335
      Participant
      quote scottie:

      Please note that three separate populations on three different continents developed these same inversions and in an “evolutionary” short space of time.

      Three separate populations on three different continents DID NOT develop these same inversions …
      The inversions developed in the ancestral population from which the studied populations disseminated. Only the frequencies of the inversions changed in response to climatic influences. This is the critical point that you have failed to understand and that renders your argument completely useless. I really wish you could see that it’s only your desire for your beliefs to be true that makes you interpret (misinterpret) the findings of science the way you do. Wanting independent origins of the inversions in different populations to support your beliefs cannot make them true. Your parents must really have done a number on your head.

    • #109674
      scottie
      Participant

      wbla3335

      I must give you credit for being consistent.
      These rather juvenile ad hominem attacks obviously make you feel better, so please carry on as I do enjoy pleasing you. 🙂

      You clearly have a problem in understanding this subject so let me try and elucidate, albeit I probably won’t be very successful, but at least its worth a try.

      The research abstract said this
       

      quote :

      We determined the magnitude and direction of shifts over time (24 years between samples on average) in chromosome inversion frequencies and in ambient temperature for populations of the fly Drosophila subobscura  on three continents. 

      The New scientist comment reads

      quote :

      Populations of fruit flies on three separate continents have independently evolved identical gene changes within just two decades, apparently to cope with global warming.

      My statement that you quoted is entirely consistent with both these statements.

      You see in English when the word develop or developed is used it refers to a process, and when something appears suddenly this word is not used. So is that clear? OK

      So you will of course notice that I used the word "developed".

      In this case the process concerned was tracked over a development period of some 24 years.
      Sadly I didn’t see the need to provide a time period and any additional details since I provided the reference paper url for anyone to check out.
      Clearly it appears that you wish to be spoon fed all the details to make matters easier to grasp.

      So, dear boy, the critical point that I have understood and sadly you appear not to have grasped, is that these inversions do not fit into the darwinian narrative.
      The other researcher makes the additional point.

      quote :

      Camille Parmesan at the University of Texas in Austin, US, who has carried out similar research, says these new findings are a warning that species may only have limited capacity within their own genomes to adapt to climate change.

      (Another negative against the darwinian process.)

      Now since you are so reluctant (dare I say afraid) to present to this forum what evolutionary process you adhere to, I can understand your frustration. I sense the same with some religionists also.

      We do know what religion you adhere to, but look, this is a science forum.
      So may I ask once again, what evolutionary process do you subscribe to?
      Come on, don’t be shy, spill the beans and put me out of my misery. 🙂

    • #109675
      wbla3335
      Participant

      You’re a real hoot, scottie. Blind faith is strange thing.

      So you didn’t read the Science paper (not a good practice) – just the abstract and the New Scientist article. As you point out, though, the paper’s abstract says,

      quote scottie:

       

      quote :

      shifts over time (24 years between samples on average) in chromosome inversion frequencies

      That says it all. Note the words "shifts" and "frequencies". I don’t read New Scientist, so I don’t know the quality of its reporting, but judging from this one article, I’m not impressed.

      quote :

      independently evolved identical gene changes

      Bad wording. The magazine’s editor should have caught this. The author should have said "genetic changes" instead of "gene changes". Readers may be misled, so I’ll forgive you for your misunderstanding. Maybe this is why the author is a journalist rather than a scientist.

      quote :

      the critical point that I have understood and sadly you appear not to have grasped, is that these inversions do not fit into the darwinian narrative

      Read the paper. It describes the "darwinian narrative". Are you saying that the authors understand their work less than you do?

      quote :

      species may only have limited capacity within their own genomes to adapt to climate change.

      A "negative against the darwinian process"? Really?

      quote :

      what evolutionary process do you subscribe to?

      Whatever’s real. By the way, there’s no single "evolutionary process". Evolution consists of many "processes". Natural selection is just one, albeit an important one. Having published research on shifts in frequencies as a result of selection, I am amused by your claim of authority. A strange thing indeed.

    • #109732
      scottie
      Participant

      wbla3335

      quote :

      You’re a real hoot, scottie. Blind faith is strange thing.

      So you didn’t read the Science paper (not a good practice) – just the abstract and the New Scientist article. As you point out, though, the paper’s abstract says,

      Well at last you may be about to engage in science, well first sentence apart that is, 🙂

      Since you claimed not to have access the the paper I stuck with the abstract. Why do you assume (indeed claim) that I have not read the paper. Please establish your facts, you do yourself no good by making these unsubstantiated claims.

      quote :

      independently evolved identical gene changes

      Bad wording. The magazine’s editor should have caught this. The author should have said “genetic changes” instead of “gene changes”. Readers may be misled, so I’ll forgive you for your misunderstanding. Maybe this is why the author is a journalist rather than a scientist

      .
      So your complaint now is semantics.
      Ok, let’s take your suggestion and use “genetic changes” instead of gene changes, and let me try and help with an understanding of what is actually going on.

      quote :

      The rapid response of this polymorphism to environmental conditions makes it a good candidate to measure
      the effect of the global rising of temperatures on the genetic composition of populations. Indeed, the long-term variation of this polymorphism shows a general increase in the frequency of those inversions typical of low latitudes, with a corresponding decrease of those typical of populations closer to the poles.
      Although the mechanisms underlying these changes are not well understood, the system remains a valid tool to monitor the genetic impact of global warming on natural populations.
      Heredity advance online publication, 29 July 2009;doi:10.1038/hdy.2009.86

      http://faculty.washington.edu/hueyrb/pd … redity.pdf

      So genetic changes on different populations on different continents (all within the same species) demonstrate a remarkable similarity. So much so that they regard this as a tool for monitoring.

      Is this a darwinian process?
      Well If it were then these changes would have to be random and clearly would not show up as the same in the different locations, but of course they do. Remember this process is a valued tool to monitor.
      So some other process must be at work. If this process is not random which it clearly is not, then it can only be non-random.

      The researchers have recognised that that these changes are tracking global climate change, if that is the case, and they are confident enough to state that this is a valuable tool in assessing the impact of climate change on the genome, then the change is a response to changing climate and thus has to be a programmed response.
      Please remember that Natural selection can only select for that which is already there. It is not a force that changes anything.

      What is causing the genetic change is either random or it is programmed.
      Notice also that the mechanism of these changes is not well understood, however what is understood is that these changes do exhibit a goal of tracking climate because that is what is evident on all three continents.
      Therefore these changes are evidently a programmed response.

      I fully understand that this runs entirely against your philosophy but that is where the evidence is pointing and no amount of disparaging remarks can alter that.

      Now at last also you have responded and informed that you adhere to “Whatever’s real.”
      Well are these frequency changes random or non random?
      What is the reality?

      You also state that you have “published research on shifts in frequencies as a result of selection,”

      Huey has a comment on this matter. In the same paper he informs

      quote :

      the Palaearctic region, Prevosti (1974) and others(reviewed in Krimbas and Loukas, 1980) determined that the frequencies of many of the chromosome arrangements of D. subobscura vary in clinal patterns that are correlated with latitude. The association between climatic variables and the D. subobscura chromosomal polymorphism has been interpreted as the result of adaptation, although some authors have argued that historical factors could explain the correlations without invoking adaptive factors (Krimbas and Loukas, 1980).

      ( my emphasis)

      So at best your research regarding selection, is being argued from within the scientific community.
      Would you be prepared to identify those papers you have published, as I would be very interested in reading them.

      Finally you state that “there’s no single "evolutionary process". Evolution consists of many "processes".”
      Whatever process you wish to identify, that process is a random one is it not?
      So lets see
      Punctuated equilibrium, is it real? Dawkins, Coyne and others say not.
      The gradual random mutation that causes speciation, Is that real? Gould Eldridge and others say not.
      The theory of symbiotic relationships driving evolution by Lynn Margulis, Is that real?
      She referred to neo darwinism as
      “a minor twentieth-century religious sect within the sprawling religious persuasion of Anglo-Saxon Biology.”
      So there for a starters is a rather rich set of realities.
      I assume therefore that you adhere to them all. 🙂

    • #109733
      AstraSequi
      Participant
      quote scottie:

      No, I am not confused. I have never stated that NS is random. The mutations are random on which NS is hypothesied to filter. This has always been my understanding of darwinian theory.

      Then what is your objection?

      The occurrence of natural selection is based on a logical argument, with four premises. (Can you reconstruct the argument?)
      – the offspring of animals are never exactly the same as their parents, but rather have small variations.
      – some of this variation gives an advantage to an animal that possesses it
      – these variations can be passed down to the next generation
      – in each generation, not all animals survive.

      If you wish to dispute the occurrence of natural selection, you have to deny one of the premises.

      quote :

      Firstly may I thank you for engaging in the science of the subject. It does make a pleasant change and of course challenges thinking processes, which is what good discussions are all about.

      I care a lot about teaching people basic biology. Of course, it takes me quite a long time to write these posts, so I hope that you’re spending time thinking about them – and if it seems like you’re able to learn, then my interest will increase. 🙂

      quote :

      Sorry but I said, “This is evidently a programmed response to climate (temperature) change.”
      You quoted me correctly the first time so I don’t understand why you misquote me now.

      I don’t see how your three “maybe” scenarios answer this question.

      I’m not sure where I misquoted you. "Evidently a programmed response" implies that there is no other plausible alternative. (I suppose I should have said "plausible" rather than "possible" in my previous quote – is that what you mean?) I then provided you with three such alternatives.

      Again, the possibilities are:
      – the mutations might be common enough that they happen all the time
      – the mutations might occur once or twice and then spread through the population by interbreeding
      – the mutations might have already been present in the ancestral population

      From my post above, I think it should be fairly clear that the third option is the most likely. However, even if it is incorrect, the others are still quite possible.

      quote :

      Please note that three separate populations on three different continents developed these same inversions and in an “evolutionary” short space of time.

      That is not the observation from the paper. The observation was that at the time of the study, the populations all had certain levels of these inversions. They then compared this to historical data showing levels of inversions in the same populations, and found that the amount of increase in the different populations was correlated with the amount of temperature change at that location.

      The interpretation "developed" is an inference that is not part of the data. Nobody has observed any population with no inversions.

      I will also point out that changes can indeed happen quite fast, so long as the environment also changes fast – it is mainly the major innovations (like fins turning into legs) that take large amounts of time.

      quote :

      How this can be the result of random mutations, which according to darwinian theory they would have to be, unless of course one is happy to play with unlikely statistics.

      It depends what you mean by "unlikely." While any individual mutation is unlikely, that doesn’t mean that it will not happen on a regular basis if you give it enough chances.

      Suppose there is a mutation that has a one in a million chance of happening – you can call this unlikely. However, if a million fruit flies are born, then it will probably happen around once. If you then wait for a thousand generations, it will probably happen around a thousand times.

      (I will also point out that for a fruit fly, a thousand generations is only about 40 years.)

      I think this might be an important point that you’re missing – in statistics, this is called a Bonferroni correction. If you roll a pair of dice, your chance of a double 6 is quite low (1/36). However, if you try twice, your chance doubles – and if you try a hundred times times, your chance of getting it at least once is very high – in fact, it would be more surprising if you didn’t get it at least once. The probability of something happening increases as the number of times it is possible to occur increases.

      I will reorder your comments in order to bring this one forward:

      quote :

      According to the theory, the mutations upon which this process rests is Random. To expect, as you suggest that changes will probably be in similar ways, is to support my view that the change is not random. You can’t have it both ways. Either change is random or it is not.

      This is essentially the same point. As long as you have enough chances, the "correct" mutations will be able to occur, and then natural selection will be able to act.

      For example, if we put some bacteria in nutrient-rich media, they will always start to grow faster after some time. This experiment only takes about a week to run, and the change will always be in the same direction.

      That is to say, we observe that natural selection produces the same result. This will happen for almost any bacteria we can grow – the new environment favors those bacteria that grow the fastest, so long as we allow enough time to pass.

      quote :

      Natural Selection is not a force but simply the naturally selected result of random forces.
      The driving force in darwinian theory is the random mutations that allow nature to select from.

      I think this is semantics. Both stages, the mutations and the selection, are required for species to adapt. If there are no mutations, no variation is generated and no change can occur. If there is no selection, only random change can occur.

      quote :

      The enviromental stress in three different continents are not the same. What the researchers noted was that the climate/latitude was the common factor. That is why they made the link with global warming.

      That is why I said:

      quote :

      In the most charitable interpretation I can think of, I suppose it is possible to make some assumptions and then say that their data is consistent with a completely deterministic model. However, you cannot say that it is evidence for such a model against natural selection, because natural selection can account for the same results quite well, and without the extra assumptions.
      quote :

      quote :

      Camille Parmesan at the University of Texas in Austin, US, who has carried out similar research, says these new findings are a warning that species may only have limited capacity within their own genomes to adapt to climate change.

      If the capacity for change is limited as this researcher warns, then what happens to the theory?
      After all climate has always been on the change throughout life’s history.

      Natural selection does not say that the capacity for change is unlimited. It might perhaps be the case, but only given enough time – the rate of change over any particular time scale is limited by the amount of pre-existing variation in the population, and the rate of production of new variation (that is, the rate of mutation).

      If the rate of change is too fast, the species is unable to adapt and goes extinct. Climate has never changed as fast as it is now in any point in Earth’s history (save perhaps the mass extinctions, and of course they didn’t go too well for life!)

      quote :

      quote :

      Are you sure you can’t think of another reason why someone would be disturbed by the observation that climate change is causing animals to undergo dramatic genetic changes?

      Well actually I cannot think of any reason why Dr Huey would be disturbed, other than this change does not sit well with evolutionary theory.

      Very well – it is related to what you said above. Drosophila is a highly successful species, with a very short generation time and the ability to adapt very quickly to new environments. When we see such a species changing very rapidly, it means that it needs to change that fast in order to stay adapted to the environment. (Or, in an even worse case, that its rate of change is at maximum, and it would be changing even faster if it could.)

      This means that any less successful species, which cannot adapt as fast as Drosophila is adapting now (and which does not have other options such as migration), is likely to be in great difficulty.

      In fact, I can tell you what the authors of the paper say, in their concluding paragraph:

      quote :

      The increasing numbers of examples documenting genetic (2–5, 8, 10, 11), as well as phenotypic (1, 2) responses, to recent climate change are not surprising from an evolutionary perspective, but nonetheless are disturbing from ecological or economic ones, because such changes signal inevitable disruptions in the distributions, population dynamics, and community interactions of organisms (1, 2).

      (My emphasis.)

      I definitely agree with you that the authors know more about this topic than us. However, you will then need to accept these statements as well. 🙂

      Also, observing rigorous data contradicting evolution would not be disturbing to scientists in the same way – it would be interesting.

      quote :

      Species change is the product of random (unguided with no goal) mutations with nature selecting any functional changes that present themselves.
      In other words the functional variation is already there for nature to select.

      I agree with your first statement. The second is not true in all cases, since mutations can and do continue to occur at about the same rate, whether selection is happening or not.

      In this case, the functional variation was indeed already there, and all three populations already had the capacity (a low level of pre-existing inversions) for that change, because they shared a common ancestor which already had that capacity, and none of them lost it in the intervening generations. I suppose you might call this "programmed," insofar as all DNA is a cellular program, but there is nothing in this that contradicts natural selection.

      Actually – what do you mean when you say "programmed"? A definition might help to clear up any misunderstanding.

      quote :

      If the change is dramatic (as you are suggesting) then new species would be expected to arise.

      Speciation requires a) differential selection on different parts of the population, b) very low gene flow between those two parts of the population, and c) the low gene flow to be maintained until enough change has occurred to prevent any future interbreeding. (There are other types of speciation, but they are not as well understood.) The authors point out in the paper that criterion b is not met – in fact, that the gene flow is unusually high. As a result, criterion c cannot be met either.

      quote :

      Why would that be disturbing?
      Surely this is the natural way, according to the theory.

      As mentioned above – the authors say it quite well. Of course, it is not as disturbing for the future of life on earth as a whole, which will probably carry on no matter what we do.

      quote :

      What evidence is there for Speciation through Natural Selection?
      It is after all the corner stone of evolutionary theory.

      I would say the "cornerstone" is in fact the logical argument I mentioned above. (See below for my answer.)

      quote :

      Darwin’s own words
      http://www.jstor.org/pss/187407 (please note my good form in naming my source :))

      Thank you. 🙂

      quote :

      Has this situation changed since Darwin’s day?
      Can someone help with some evidence.

      Most definitely. I suggest you read http://en.wikipedia.org/wiki/Speciation, and also any included citations if you want to investigate further. Please note in the opening paragraph, "Observed examples of each kind of speciation are provided throughout."

      quote :

      Lets try and make the question a little easier.

      What evidence is there that random mutations and natural selection can produce new functional biological information.

      This is not the same question. I will answer you if you can demonstrate that you understand why that is. 🙂

    • #109737
      wbla3335
      Participant
      quote scottie:

      Is this a darwinian process?
      Well If it were then these changes would have to be random

      Yes, it is darwinian. Selection is not random.

      quote :

      What is causing the genetic change is either random or it is programmed.

      Or it’s nonrandom selection.

      quote :

      Notice also that the mechanism of these changes is not well understood

      The mechanism of the changes is very well understood. How the inversions confer an advantage is not understood (as far as I know).

      quote :

      Therefore these changes are evidently a programmed response.

      Or therefore you don’t understand what selection is.

      quote :

      Well are these frequency changes random or non random?
      What is the reality?

      Nonrandom. The reality is selection.

      quote :

      So at best your research regarding selection, is being argued from within the scientific community.

      Correlations of frequencies are not necessarily the result of selection. They may be due to historical factors. So? You conclude from this that selection is doomed within the scientific community. Believe whatever you’ve been programmed to believe.

      quote :

      Would you be prepared to identify those papers you have published, as I would be very interested in reading them.

      No. Anonymity allows me to be more acerbic that I normally am. There’s no lack of other material at your disposal.

      quote :

      Finally you state that “there’s no single “evolutionary process”. Evolution consists of many “processes”.”
      Whatever process you wish to identify, that process is a random one is it not?

      Some are, some aren’t.

      quote :

      Punctuated equilibrium, is it real? Dawkins, Coyne and others say not.

      Are evolutionary rates universally constant? No. I agree with the general premise that "gradualism" is not the only game in town, as do Dawkins and Coyne and most biologists. I do not support the extreme position that evolution occurs ONLY in bursts, which is also the source of Dawkins’ and Coyne’s objections.

      quote :

      The theory of symbiotic relationships driving evolution by Lynn Margulis, Is that real?

      Most biologists think not. I’m sure it contributes, but as an exclusive alternative to mutation as the major source of variation, unlikely.

      quote :

      So there for a starters is a rather rich set of realities.
      I assume therefore that you adhere to them all. 🙂

      You’re a very black-or-white kind of a guy, aren’t you. Complex systems are complex because they don’t have one controlling influence. Such thinking as yours is a function of your belief in a deity that creates and controls everything. Your belief may also be preventing you from getting the idea into your head that evolution is not a totally random thing. If selection were random, I wouldn’t buy it either. Turn off your deistic filter and read the paper. Read what it actually says and not what you want it to say.

    • #109766
      scottie
      Participant

      wbla3335

      I was under the impression that biologists were always eager to share their results, you appear to be the exception, prefering to be acerbic instead.
      Oh well some like to wallow in bitterness and others enjoy the beauty of life. It takes all sorts.

      You did however lift my spirits with some attempted scientific dialog but sadly then dumped me again with reverting back to your deity monolog.
      Still I suppose we are at least getting somewhere.

      Now I could respond line by line but will choose to concentrate on your last little bit of science which I believe is at the heart of this matter.

      You have raised the issue of complexity and in a very precise way that deserves clarification.

      quote :

      Complex systems are complex because they don’t have one controlling influence.

      You are missing a trick here.

      There are in fact three subsets to complexity. You appear to be aware of only one.
      I would recommend you read this paper (peer reviewed of course) in the NIH journal PubMed Central.
      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208958/
      These three are :-
      Random Sequence Complexity (RSC); Ordered Sequence Complexity (OSC); Functional Sequence Complexity (FSC).

      Complexity can pertain without any controling influence. You are correct.
      This type of complexity is Random Sequence Complexity (RSC) Please inform yourself by reading this paper.

      You should have noticed that I refer to functional design, check my posts.
      Functional design can be complex or it can be simple, I have given examples of both in the past.

      Functional design is one of the subsets of complexity. It is (FSC) Functional Sequence Complexity.
      Functional design always has a controlling influence.

      So we come down to the fundamental question in biology.
      Is the cell just a complex system that has evolved from the bottom up, I.e. just a sum of parts that make up the whole I.e (RSC)
      OR is it the product of functional design that the individual parts grow out of. (FSC)

      That seems to be the major difference between our views (without of course all the deity gibberish)
      Would you kindly read the paper so at least we have a common foundation to discuss from.
      If you have any other papers on this issue of complexity please inform and I will be happy to read accordingly.

    • #109769
      wbla3335
      Participant
      quote scottie:

      I was under the impression that biologists were always eager to share their results, you appear to be the exception, prefering to be acerbic instead.
      Oh well some like to wallow in bitterness and others enjoy the beauty of life. It takes all sorts.

      As I’ve said, you’re a real hoot, scottie.

      quote :

      Now I could respond line by line

      You’re wise to abandon your last attempt at debunking evolution. It wasn’t going anywhere for you, like your other attempts.

      I had a look at the abstract of the article you linked to. As a scientist, it brought a smile to my face. The bells that went off induced me to have a look into the authors’ credentials. Surprise, surprise. For those interested, others have gone further than I have:

      http://scienceblogs.com/pharyngula/2012 … litera.php

      Intelligent design, yet again. I’ve had my suspicions about you, scottie, hiding behind this deist mask. I’ll decline your offer to read the linked paper. As I’ve said before, I don’t like to waste my time.

    • #109779
      JackBean
      Participant

      scottie said

      quote :

      You did however lift my spirits with some attempted scientific dialog but sadly then dumped me again with reverting back to your deity monolog.

      😀 😀

      quote scottie:

      I would recommend you read this paper (peer reviewed of course) in the NIH journal PubMed Central.
      link

      (my emphasis)
      Why did it remind me of this? http://www.chem1.com/acad/webtext/sci/p … i.html#REC

    • #109796
      canalon
      Participant
      quote scottie:

      wbla3335
      There are in fact three subsets to complexity. You appear to be aware of only one.
      I would recommend you read this paper (peer reviewed of course) in the NIH journal PubMed Central.
      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208958/
      These three are :-
      Random Sequence Complexity (RSC); Ordered Sequence Complexity (OSC); Functional Sequence Complexity (FSC).

      Dr Abel seem to have gone a bit far for help considering his latest papers, but as far as I know, Dr Trevors is a competent if a bit strange microbiologist. But that is beyond the point.
      I could also argue that the fact that you did not grasp that Pubmed Central is not a journal but a repository for papers and that your failure to be able to identify the publication in which a paper is published (Theoretical Biology & Medical Modelling) do not speak highly of your attention to details.

    • #109811
      scottie
      Participant

      Canalon

      Nice to have you back in the ring 🙂
      So Dr Abel is a bit of a strange microbiologist?
      Well I’m sure that is just an opinion you have, for what it’s worth.
      Perhaps we could also have your opinion on the science he posits.
      Remember he has produced a paper on the principles of complexity, and has also set out 4 null hypotheses that could falsify his posits.
      So how about, as a scientist, at least attempting to falsifying what he has put out instead of resorting to and indeed relying on rather condesending rhetoric.
      Surely you can do better than this, like pointing out what is wrong with the paper.

      quote :

      I could also argue that the fact that you did not grasp that Pubmed Central is not a journal but a repository for papers and that your failure to be able to identify the publication in which a paper is published (Theoretical Biology & Medical Modelling) do not speak highly of your attention to details.

      You could argue but I take it you are not going to then. 🙂
      If you look at the top left hand insert you will note it says “PubMed Central Journal List.”
      How far away is that from what I wrote. Really now, is this the best you can do.?

      Jackbean
      Good to see you are having some fun again. 🙂

    • #109812
      scottie
      Participant

      wbla3335

      You should not misjudge why I have not taken up on the details of your assertions on NS.
      You clearly are in need of some education on the subject so like all good teachers, when a pupil is missing a fundamental principle on a matter,it is good teaching practice to explain that first. 🙂

      It appears, the reason you have those views is because of what Lynn Margulis recognised.
      Her rather amusing description of the study of biology, actually does recognise a fundamental problem within the environment in which biology is conducted.

      Many biologists have become fixated on DNA (the genome)

      For instance take the stated goal of The Human genome project ( in the projects own description)

      quote :

      identify all the approximately 20,000-25,000 genes in human DNA,
      determine the sequences of the 3 billion chemical base pairs that make up human DNA,
      store this information in databases,
      improve tools for data analysis,
      transfer related technologies to the private sector, and
      address the ethical, legal, and social issues (ELSI) that may arise from the project.

      http://www.ornl.gov/sci/techresources/H … bout.shtml

      You don’t find any mention of the cell as a whole unit.
      Now why is this?
      After all is not the genome just a part, albeit an important one, of cellular structure?
      So lets remind ourselves on what actually is the role of DNA in the context of cellular processes.?

      This is a molecule that by itself is without meaning for the organism, it cannot do anything.
      Harvard biologist Richard Lewontin describes it as “ a dead molecule among the most nonreactive, chemically inert molecules in the living world”.

      Are all molecules involved in life processes made by DNA?
      The answer is clearly NO
      1) As already noted DNA by itself cannot make anything.
      2) Many of the molecules that a functioning cell uses, like lipids and carbohydrates, do not come from DNA. We note that the crucial functioning of metabolism, which is the transformation of nutrients in the cell, is not in any real sense controlled by DNA. In fact metabolic processes send signals to DNA when it’s services are required.
      3) The proteins and non coding RNA that do derive from DNA are extensively and significantly modified by processes in the cytoplasm, in order to function correctly. In other words DNA is just a rough template of what is required.
      4) Enzymes and other proteins essential for transcribing DNA are not mere products of DNA because they already have to be existing to carry out the production.
      5) DNA far from being responsible for everything in the cell, is itself the responsibility of the cell to be accurately preserved

      In reality all the constituents parts, including DNA originate from the cell and organism as a whole.

      How is this a fact and how do we know it?

      Well lets take just one strand of information, the nuclear organisation of chromosomes.

      Every chromosome is positioned in a particular region or domain of the nucleus, and this territorial positioning varies with tissue type and the stage of the organism’s development.
      Chromosomes or parts of them near the centre of the nucleus are more intensively expressed than those near the outer periphery, which tend to be repressed. (note this is just one very simple strand of knowledge)

      Now this organisational structure has nothing to do with whether a random mutation effects a particular gene or whether natural selection somehow determines this positioning. Yet this positioning correlates very specifically with the differentiating process that makes the various types of cell and tissue.
      This is a level of organisation clearly above that of DNA.
      Now I could go on and enumerate further on chromosome organisation but that would just be re-enforcing the point.
      Also the organisation of the cell involves much more than the chromosomes themselves.

      The DNA code itself undergoes a metamorphosis.
      For example certain bases are subject to methylation. This is not a simple tagging or marking of these bases, but a complete transformation of the molecules that display different qualities.
      Some of these methylation patterns are inherited, but for the most part they are not, and for good reason.
      The undifferentiated condition of the zygote is crucial for future development. It would be disastrous if tissue specific patterns of methylation in say liver or kidney were passed on to the zygote.
      Therefore in general, these patterns need to be wiped clean.
      This is achieved by a wave of demethylation that is passed along each chromosome shortly after the fertilization of an egg and is completed by the time of embryonic implantation in the uterus.
      Then, along comes a fresh wave of methylaion that is shaped by the embryo itself and gives a fresh epigenetic start.
      If this embryonic methylation is blocked the organism dies.

      So this structuring and restructuring of DNA by the surrounding processes is as central to a developing organism as the DNA code itself. However this control does not eminate from DNA.

      As I have pointed out, this is but a strand of epigenetic processes that are controlled by methods beyond DNA.
      Following the initial draft of the Human genome project in 2001, William Bains, chief scientific officer at Amedis Pharmaceuticals in the United Kingdom, so rightly stated

      quote :

      The chances that genome properties can be used to predict organismal ones is remote. Genomics and its daughter technologies are valuable instruments in the analysis of cells and tissues. They provide means of exploring biological processes and phenomena. However … they will not often address most human needs….

      The Parts List of Life,” Nature Biotechnology 19 (2001): 401-402.
      So what we have here is organisation at the very highest level controlling in a top down way DNA Methylation, Differentiation and all other processes.
      One overarching control of cellular processes that keeps the cell in equilibrium, but which rapidly deteriorates back down to their constituent parts at death, when this control ceases.

      Now again I could go on enumerating the way in which the various processes that we have so far understood, are controlled from higher layers of organisation within the cell.

      Yet, and here is the point, we have an evolutionary view, posing as scientific, that tries to project the idea that this is all explained in a bottom up method, where the whole is simply a sum of it parts and even more than that, the whole is somehow brought about by random mutations on just one of it’s parts, DNA.

      Is this really a scientifically credible position to take.

      There is clearly nothing random about cellular life processes.
      And yet to point this out so often elicits such pejorative responses. You being a good example.
      It seems to me that a philosophical raw nerve is being touched.

      But, just to nail down this point, study this paper about the regulation by and of p53 master sensor of stress.
      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857175/
      Tied Up in Loops: Positive and Negative Autoregulation of p53
      In part it states

      quote :

      Of these, p53/mdm2 is the master autoregulation loop, and it dictates the fate of an organism by controlling the expression level and activity of p53. It is therefore not surprising that this autoregulation loop is itself subject to different types of regulation, which can be divided into two subgroups…

      So here we have the master controlling sensor is itself subject to a master controlling process
      (one of several regulatory loops) that dictates the fate of the organism.

      This master loop, is in turn regulated, in various manners, by a whole series of “multi-layered” processes, including some that are themselves “subject to direct regulation by
      mdm2” — that is, they are regulated by an element of the regulatory loop they are supposed to be regulating.

      It is hard to begin to describe the stunning complexity surrounding and supporting the diverse performances of the p53 protein. But it is now clear that such “regulatory” processes extend outward almost without limit, connecting in one way or another with virtually every aspect of the cell. ( And all of this is supposed to have come about by random unguided processes, Really!!)

      So please when you make statements such as you have that

      quote :

      Complex systems are complex because they don’t have one controlling influence.

      (a)You are certainly not speaking from knowledge of cellular processes.
      (b) Your understanding of complexity is certainly in need of further education.

      Now with that little bit of education which hopefully you will have absorbed, I will be able to take you a bit further down the path of your Natural Selection ideas.

    • #109815
      JackBean
      Participant

      The Human genome project is interested (only) in DNA? You must be kidding! And I though that the genome projects get usually involved in proteomics and metobolomics as well.

      Again and again all the same bullshit, huh? Without DNA you will get nothing. If there are no genes, there are no lipids, no sugars, no proteins, no siRNA. Of course DNA doesn’t do any real work, but guess what. That’s how is it going in the cell. Nobody is arguing about that.

      quote scottie:

      If you look at the top left hand insert you will note it says “PubMed Central Journal List.”
      How far away is that from what I wrote. Really now, is this the best you can do.?

      At least on that link, before you use it as argument. http://www.ncbi.nlm.nih.gov/pmc/journals/ As you can see it is PubMed Central – Journal List i. e. list of journals listed in PubMed Central. Obviously nothing as PubMed journal.

    • #109821
      wbla3335
      Participant
      quote scottie:

      You clearly are in need of some education on the subject so like all good teachers, when a pupil is missing a fundamental principle on a matter,it is good teaching practice to explain that first. 🙂

      You’re a real hoot, scottie. The only thing a creationist can teach me is how to close my mind, which I’m reluctant to do. I haven’t bothered to read very much of your last post, but what I did see didn’t inspire me to waste my time on it. You might better serve yourself by being succinct and organised.

    • #109825
      AstraSequi
      Participant

      Scottie, I’d like to point out that you have not yet replied to my most recent post.

    • #109827
      canalon
      Participant
      quote scottie:

      You could argue but I take it you are not going to then. 🙂
      If you look at the top left hand insert you will note it says “PubMed Central Journal List.”
      How far away is that from what I wrote. Really now, is this the best you can do.?

      In fact I should apologizing for posting by error only the beginning of an answer to take care of my mini monster at home, and never corrected or completed as I did not have time to come and correct my mistake. So yes, Scottie I will not argue your lack of attention to details.
      What I wanted to say is that your wondrous paper written by the now provably mentally troubled Dr Abel (see astrasequi post), and the competent but Weird Jack Trevors in Theoretical Biology & Medical Modelling, although published does not have garnered a strong interest: If you look on google scholar you will notice that it has been only cited by its own authors. Usually not a good sign. As a biologist, and not an information scientist, it is hard to comment on the content. Neither has the notion of functional sequence complexity, which seems to have originated in this paper, seem to have caught on much beyond Dr Abel’s own paper.

      But if I understand what is explained Abel and Trevors are arguing that in order to create a self replicating molecule, it would somehow require that a molecule was able to constrain the sequence that will follow (i.e If A then B then C then D, etc…) in order to be able too create enough copy of itself. That would be interesting, but AFAIK that is not what evolution argue. Which would be closer than a molecule that made it just a bit more likely to increase the formation of identical molecules in solution was our very first ancestor. In fact that the monomers do not need to carry any information, just that a finished product can constrain the world around it. And since that would make the notion of FSC irrelevant, that would explain why the absence of disproving the 4 null hypothesis as little to no interest.

      But before you answer this post will you answer my question about the circularity of the designer argument? Or even Astrasequi’s question.

      By the way, I am tired of your refusal to answer direct questions simply and your refusal to enter a discussion. So will you finally answer? Preferably in less than your usual 140 + k signs

    • #109834
      LeoPol
      Participant

      (richarddawkins.net/articles/643549-origin-of-life-challenge-how-did-life-begin#page4) 😛

      In order for a origin of membrane – much organic matter is not necessary – only the membrane lipids of different isoforms, it is necessary also to a weak emission core of the star created a flow of heat through the surface phase transition, and yet not interfere with a certain oscillation – vibration … In general, all this is difficult to discuss now, not yet studied the process of emergence and functioning in a natural cell membrane of this very … – Active situational model – a kind of natural intelligence and personality!! But when it all becomes clear, then we can speculate about the conditions and awakening him to the protostar, or on some planet out there.

      So. Life has two interacting components. One component – natural intelligence. The second component – the polypeptide-nucleic technology – a self-contained database on DNA, which is implemented through the input-output – RNA into the polypeptide interface. What comes first? I believe that natural intelligence is primary, and polypeptide-nucleic technology – is secondary. In this sense, the theory of “Evolution of the primary replicators to Homo Sapiens” should be replaced by a theory of “Abiogenesis, and social development of the primary natural intelligence”, which later created and developed polypeptide-nucleic technology. http://richarddawkins.net/articles/6435 … egin#page4

    • #109841
      Nick7
      Participant
      quote wbla3335:

      quote Nick7:

      Therefore, allocating the role of the designer to “the natural world” also seems to be quite subjective to me, and I don’t see how one can rationally quantify it (likely or unlikely…)

      Everything that goes on in heads is subjective, but some of it can be based on evidence. In the absence of evidence for the supernatural, some of us consider the natural to be more likely. Some of us don’t. .

      Well, 1st, it depends on what you choose to use as a starting point to measure your “natural”. (sorry for the delay, by the way). Life is a sophisticated carbon-based nanotechnology and it heavily relies on preconditions. Where did the preconditions for the complex life come from? AstraSequi , on the previous page, used dice in the example ( “If you roll a pair of dice, your chance of a double 6 is quite low (1/36). However, if you try… a hundred times times, …it would be more surprising if you didn’t get it at least once.” ) What if I give you a pair of dice with no 6 present on them at all, how many tries do you need to roll a double 6? I’ve tried to make this point several times… Why do you assume that preconditions just happened? For instance, what known cosmic law states that every universe popping into existence must have so many constants in physics? What known cosmic law requires nuclear resonances in the creation of fundamental blocks of life (Carbon and Oxygen, in our case) to be so “tuned”? ……the point is that you choose to assume that all the fundamental pillars of our existence just happened through some unknown, but purely mechanistic and unguided processes. Now, I can’t find my membership card of the The National Academy of Sciences and my pooch has chewed the certificate confirming my Ph.D. in Molecular Genetics, but I’ll risk to state that I see one fat-%#s axiom sitting in the foundation of your reasoning that leads you to that concept of “unlikely” behind the idea of “creation”. Evolution doesn’t really seem to falsify creation, it falsifies the meaning you put into the word creation (the way you believe it should’ve happened if it were true).

      quote wbla3335:

      quote Nick7:

      And he usually provides links to the opinions of the more-than-qualified individuals.

      He provides links to studies. The opinions he gives are his own. The authors of the studies are not claiming the falsification of evolution nor the existence of a designer.

      Here is the original opinion on F. Collins’ Brown Rat one by Sternberg I mentioned before http://www.evolutionnews.org/2010/03/be … 32981.html (maybe it’s just a reprint on ID site, but that’s where the Scottie’s opinion in this case came from). I’ve really got no time to google them all up, but I’d say that I think that at least 50% (and it’s very conservative estimate) of the opinions presented by Scottie were most likely originated by the peers of the papers’ authors. But those are opinions. End if studies’ authors have atheistic opinions attached to the findings of their research, those are also just opinions. That’s where I differ from both you and Scottie… ALL of us are not talking science here. We’re talking philosophy encrusted with supporting scientific evidence. Speaking of which….
      It’s not that there is no evidence of what you call “supernatural” (don’t really like this word). It’s what you would or wouldn’t accept as evidence. Scientific method works well with the evidence which supports purely mechanistic and consistently replicable natural phenomena. For instance, nobody questions the validity of the quantum entanglement in physics, even though this bizarre phenomenon is absolutely not understood and appears to be rooted somewhere beyond the realm of observable reality. Why? Because it’s easily replicable in any properly equipped lab in the world. Once you move into grey areas, scientific method can (and does) sometimes falter under the weight of biases, preconceptions, dominant believes, politics, etc. Here is an interesting article on that http://www.newyorker.com/reporting/2010 … ntPage=all ). The article describes the “decline effect”… A couple of extracts: “…selective reporting is everywhere in science….We cannot escape the troubling conclusion that some—perhaps many—cherished generalities are at best exaggerated in their biological significance and at worst a collective illusion nurtured by strong a-priori beliefs often repeated.” ….. Such anomalies demonstrate the slipperiness of empiricism. …. We like to pretend that our experiments define the truth for us. But that’s often not the case. Just because an idea is true doesn’t mean it can be proved. And just because an idea can be proved doesn’t mean it’s true. When the experiments are done, we still have to choose what to believe."
      So….for example, would you accept a possibility of “supernatural” explanation for this http://www.sheldrake.org/Articles&Paper … e_abs.html ? Why not? If there is something else out there as far as general relativity and quantum physics go, why our (and animal) consciousness is being ordered to stay within our skulls if the experiments above (and collective experiences of numerous people) suggest other possibilities? Has our consciousness been already dissected and reduced to the molecules in our brains?

      And one more thing…….. about collective experiences. I like science, but I don’t like scientism. Yes, everything that goes on in heads is subjective (as you’ve put it), but it’s still an experience. If these collective experiences make similar independent claims (across different ages, continents and cultures), it makes me suspicious that there might be something behind them. When Dawkins was asked about it, he said that his personal “anecdotal experiences” © do not matter. Well, not everyone is as lucky as Dawkins.
      To make a long story short… I view the position outlined by neuroscientist D. Eagleman ( http://en.wikipedia.org/wiki/Possibilianism )as being more scientifically honest: "Our ignorance of the cosmos is too vast to commit to atheism, and yet we know too much to commit to a particular religion. A third position, agnosticism, is often an uninteresting stance in which a person simply questions whether his traditional religious story (say, a man with a beard on a cloud) is true or not true. But with Possibilianism I’m hoping to define a new position — one that emphasizes the exploration of new, unconsidered possibilities. Possibilianism is comfortable holding multiple ideas in mind; it is not interested in committing to any particular story."

      quote wbla3335:

      Your beliefs, scottie, are shared by very few people in this world, and you may want to ask yourself why that is. There are lots of theists, fewer deists…

      This one is easy. To become a deist or an atheist or …. whoever other non-certifiably-theist, one has to start thinking. Thinking, just like anything else, requires prerequisites – extra time, education, etc. And most of the people just do not have that kind of luxury. Most of the people in this world are born into their believes, and after that they literally survive on several bucks a day; therefore, they do not think about the origins of their existence, but they mostly think about how to maintain their existence and how not to pop out of it prematurely. And why would anyone be deterred from independent thinking by the “majority” argument anyway? Even in science there is an expression “Science advances one funeral at a time”. And outside of science, following the majority is one of the most assured way to fall off the cliff.

      quote wbla3335:

      Complex systems are complex because they don’t have one controlling influence.

      Actually, I also stumbled over this one. Complex systems are indeed complex because they have a gadzillion number of variables defining them. We owe to this complexity, without it no complex creatures would exist (that’s how I started this post). But outside of our bodies, complex interactions result in what is studied by the chaos theory. If I try to predict a precise trajectory of a little slice of, ….. lets say, polyurethane foam sucked into my vacuum cleaner, I doubt that it can be easily done. But based on the “controlling influence” of the vacuum cleaner properties and, most importantly, the “controlling influence” of the structure of polyurethane, I can predict that not only my slice of foam will stay intact, but it will also “adapt” its shape to the shape of the trash it’s squeezed against inside, whatever that may end up to be. You take that embedded “plasticity” that took us from a cosmic dot to Precambrian slime to A. Einstein for granted, and I have to be convinced.

    • #109844
      canalon
      Participant
      quote Nick7:

      Why do you assume that preconditions just happened? For instance, what known cosmic law states that every universe popping into existence must have so many constants in physics? What known cosmic law requires nuclear resonances in the creation of fundamental blocks of life (Carbon and Oxygen, in our case) to be so “tuned”? ……the point is that you choose to assume that all the fundamental pillars of our existence just happened through some unknown, but purely mechanistic and unguided processes. Now, I can’t find my membership card of the The National Academy of Sciences and my pooch has chewed the certificate confirming my Ph.D. in Molecular Genetics, but I’ll risk to state that I see one fat-%#s axiom sitting in the foundation of your reasoning that leads you to that concept of “unlikely” behind the idea of “creation”. Evolution doesn’t really seem to falsify creation, it falsifies the meaning you put into the word creation (the way you believe it should’ve happened if it were true).

      You are very right and very wrong at the same time. You are right that no law or anything else requires anything from any universe popping in existence. And that the fact that all the atoms are tuned so wonderfully (whatever that means) is essential to our existence. But you are very wrong in that it is not because of us that those things are so well tuned to allow life, but that life as we know it is there only because all those stuff happened to work together. If they had not been, you would not be there mistaking causes for consequences. For all we know there might be an infinite number of universe devoid of stupid creatures to wonder how nice was their non existent creator to tune everything to allow them to exist…

    • #109846
      AstraSequi
      Participant
      quote :

      Life is a sophisticated carbon-based nanotechnology and it heavily relies on preconditions. Where did the preconditions for the complex life come from? AstraSequi , on the previous page, used dice in the example ( “If you roll a pair of dice, your chance of a double 6 is quite low (1/36). However, if you try… a hundred times times, …it would be more surprising if you didn’t get it at least once.” ) What if I give you a pair of dice with no 6 present on them at all, how many tries do you need to roll a double 6? I’ve tried to make this point several times…

      …I’m quite sure I was talking about something completely different, specifically mutations. The analogy is meant to show that if there is a small chance of something, then you can be very certain of getting lucky if you try enough times. You can replace the analogy with two one-million-sided dice if you want, so long as you get a trillion chances.

      If you want to claim that there is literally zero chance for something to happen, you need a rigorous mathematical proof – nothing else is sufficient.

      Also, a few other points that I thought I should mention (I suppose I’m jumping into someone else’s discussion, but I like talking about science at the philosophical level :)):

      quote :

      Why do you assume that preconditions just happened? For instance, what known cosmic law states that every universe popping into existence must have so many constants in physics? What known cosmic law requires nuclear resonances in the creation of fundamental blocks of life (Carbon and Oxygen, in our case) to be so “tuned”? ……the point is that you choose to assume that all the fundamental pillars of our existence just happened through some unknown, but purely mechanistic and unguided processes.

      It is not an assumption – it’s just that there is no evidence in any direction (at least as far as I know). For example, there is no way to falsify the hypothesis that our universe was created by highly advanced aliens, and I probably wouldn’t be surprised if this were true. However, since pretty much everything else in physics is "mechanistic and unguided," it is reasonable to say that this might be as well.

      Also, if you wish to make a fine-tuning argument, you must remember to consider the anthropic principle. (See http://www.anthropic-principle.com/primer.html, and also canalon’s previous post.)

      quote :

      Evolution doesn’t really seem to falsify creation, it falsifies the meaning you put into the word creation (the way you believe it should’ve happened if it were true).

      I don’t think this makes sense. The only thing that you can falsify is a hypothesis.

      quote :

      Scientific method works well with the evidence which supports purely mechanistic and consistently replicable natural phenomena.

      The scientific method works well with consistently replicable phenomena. As long as causality exists and remains consistent, the scientific method will work.

      quote :

      So….for example, would you accept a possibility of “supernatural” explanation for this http://www.sheldrake.org/Articles&Paper … e_abs.html ? Why not?

      The probability of bias or error in a single study is much higher than the probability that a "supernatural" force exists, times the probability that this force enables telepathy over long distances, times the probability that it is occuring in this circumstance, times the probability that nobody else would have found rigorous evidence for it even though it actually existed…This is where you get the phrase, "extraordinary claims require extraordinary evidence."

      That being said, a possibility? Sure – the only impossibilities are those that have mathematical proofs behind them. However, the probability is so low, given our current state of knowledge about how the universe works, that it is not reasonable to think that it might be true.

      Also, perhaps on an unrelated note – the definition of "supernatural" is basically equivalent to "that which cannot be explained by science," so I would call it a truism that science only explains things that are "natural." If science explains something, then it is no longer considered supernatural (for example – sunrise, reproduction, rainbows.) So I would say that I don’t like using the word "supernatural" either. 🙂

    • #109847
      wbla3335
      Participant

      Thanks guys, you’ve saved me a lot of bother. For me, "supernatural" simply means outside of nature.

    • #109848
      AstraSequi
      Participant

      You’re welcome, then. 🙂 (Still, though, I didn’t respond to everything, if there’s anything else you want to reply to.)

      quote wbla3335:

      For me, “supernatural” simply means outside of nature.

      I agree with this as well – I would just say that "nature" is the same thing as "everything that can (in principle) be explained by science." I can’t really think of anything that might be in principle unexplainable by science – or perhaps a better way to say it would be, something that is impossible in principle to gather evidence about, under any circumstances of time, space, etc – yet not be considered "supernatural."

      Of course, part of the point was that the word doesn’t have a very useful meaning, so I suppose it doesn’t matter. 🙂

    • #109899
      scottie
      Participant

      AstraSequi

      I have just returned to the forum after being away for a few days.
      Which question of yours do you wish me to address?

      Also
      Canalon could you repeat your question please.

      Thanks

    • #109910
      scottie
      Participant

      AstraSequi

      I have tried to catch up with the postings, now I am not sure but is this the question you wish me to address.

      quote :

      Then what is your objection?
      The occurrence of natural selection is based on a logical argument, with four premises. (Can you reconstruct the argument?)
      – the offspring of animals are never exactly the same as their parents, but rather have small variations.
      – some of this variation gives an advantage to an animal that possesses it
      – these variations can be passed down to the next generation
      – in each generation, not all animals survive. 

      If you wish to dispute the occurrence of natural selection, you have to deny one of the premises. 

      I understand the logic of the argument and I have no problem with it.
      This logic is perfectly acceptable.
      The problem is in how the variation arises.

      However I believe the question of definitions is important here.
      According to berkley edu NS is described thus:-
      http://evolution.berkeley.edu/evolibrary/article/evo_32

      quote :

      The genetic variation that occurs in a population because of mutation is random-but selection acts on that variation in a very non-random way: genetic variants that aid survival and reproduction are much more likely to become common than variants that don’t. Natural selection is NOT random!

      So, to understand NS is it not first necessary to get clear what a mutation is and then determine how it is regarded as random, because it appears according to berkley edu, that all genetic variations are random.

      What a mutation actually is, needs to be determined, since there are those who have a different description of mutations.

      For instance Lindell Bromham, Centre for Macroevolution and Macroecology, School of Botany and Zoology, Australian National University, Canberra, Australia describes mutations this way

      quote :

      The term mutation can refer to any process that changes the genetic information in the genome, including DNA insertions, deletions and rearrangements.

      http://www.tempoandmode.com/wp-content/ … oels08.pdf

      Alan F Wright, MRC Human Genetics Unit, Edinburgh, UK has this to say

      quote :

      Genetic variation is generated continuously by the mutational process, but its persistence in the genome is determined by different historical and genomic factors.

      http://evolution.unibas.ch/teaching/evo … ations.pdf

      It would be good if we can, as a start, agree on what we mean a mutation actually is.

      My own understanding of mutation harmonises with the two descriptions I have cited ( Bromham and Wright) and not that of berkley edu.
      So which definition do you understand to be the correct one?

      Also when berkley edu sets out to describe what a Random mutation is, notice what it states

      quote :

       Mutations are “random” in the sense that the sort of mutation that occurs cannot generally be predicted based upon the needs of the organism.

      So therefore, before a mutation can be classified as random or not, (although berkley seems to suggest that all mutations are random) we have to determine what the needs are of the organism.
      How then is that achieved?
      Can you help out here?

    • #109947
      AstraSequi
      Participant
      quote scottie:

      I have tried to catch up with the postings, now I am not sure but is this the question you wish me to address.

      …I was hoping that you would address the entire post, not just one part of it.

    • #109955
      scottie
      Participant

      yes I intend to address your entire post.
      But I do have to start somewhere don’t I?

      So can we agree on what each of us means when we use the term mutations. As I have demonstrated there are differing views on what constitutes a mutation.
      The talkorigins essay by Richard Harter states that :-

      quote :

      It is important to realize that mutations do not occur in response to the environment. They simply happen.

      http://www.talkorigins.org/faqs/mutations.html
      This appears to agree with berkley edu.
      I have given you my understanding, could you let me know what your understanding is, so at least we don’t get to talk across each other.

    • #109961
      AstraSequi
      Participant
      quote scottie:

      yes I intend to address your entire post.
      But I do have to start somewhere don’t I?

      I can wait for you to finish; in attempting to devise answers, I think you will be able to get closer to resolving any confusion. I see no contradictions or "differing views" in any of the phrases you have quoted – for example, as you think, you might try to specifically identify what you think the difference is.

    • #109962
      LeoPol
      Participant

      So, Origin of Life.
      In order for a origin of membrane – much organic matter is not necessary – only the membrane lipids of different isoforms, it is necessary also to a weak emission core of the star created a flow of heat through the surface phase transition, and yet not interfere with a certain oscillation – vibration … In general, all this is difficult to discuss now, not yet studied the process of emergence and functioning in a natural cell membrane of this very … – Active situational model – a kind of natural intelligence and personality!! But when it all becomes clear, then we can speculate about the conditions and awakening him to the protostar, or on some planet out there.

      So. Life has two interacting components. One component – natural intelligence. The second component – the polypeptide-nucleic technology – a self-contained database on DNA, which is implemented through the input-output – RNA into the polypeptide interface. What comes first? I believe that natural intelligence is primary, and polypeptide-nucleic technology – is secondary. In this sense, the theory of “Evolution of the primary replicators to Homo Sapiens” should be replaced by a theory of “Abiogenesis, and social development of the primary natural intelligence”, which later created and developed polypeptide-nucleic technology. http://richarddawkins.net/articles/6435 … egin#page4

      But there is an interesting aspect! Scientists can learn everything you can observe and verify, and Theologysts – thinking about the else far that beyond the border of observable reality. Here, for example, the active situational model is on the cell membrane, and that this membrane? Interacting electromagnetic fields of electronic orbitals. Hence, the intellect – the active situational model in the electromagnetic field. And what is the electromagnetic field? What, in general, the continuum? Yeah … Theologians would say – it is a membrane of Spirit! Well, ok! It does not contradicts the rational science! 😕 http://spacenoology.agro.name/?page_id=5519

      I adhere to the hypothesis that the engineering design occurred during the rare periods when the developed technological civilizations. This has happened very rarely. But for a very long interim periods ran the Darwin’s Natural Selection, as well as Dawkins’s His Majesty the Selfish Gene! At the same time created by the engineering design technologies were degenerative effects of natural selection. As a result of species to varying degrees, lose universalism, but due to hypertrophy of various technological relics specialize in different biological niches. 😉

    • #109971
      scottie
      Participant

      AstraSequi

      quote :

      I can wait for you to finish; in attempting to devise answers, I think you will be able to get closer to resolving any confusion. I see no contradictions or “differing views” in any of the phrases you have quoted – for example, as you think, you might try to specifically identify what you think the difference is.

      Since you see no difference in the views I have presented, you have answered my question.
      I can therefore move on and respond with perhaps more freedom than I had anticipated.

      There are random mutations that rearrange the DNA of the cell. These mutations are invariably the result of copying errors, breakdown in regulating functions like error correction, and DNA damage from environment like from chemical or UV radiation sources.

      There are also more mutations in DNA, by orders of magnitude, as a result of regulated cell processes, than those that are random in nature.

      The random mutations that do occur are invariably deleterious to the organism and are quite naturally the subject of intense study to solve or prevent health problems like cancers.

      Now
      Back in 1983 in her Nobel laureate lecture Barbara McClintock described various ways that an organism uses to respond to stress, among them by altering its own genome. This is what she said.

      quote :

      Some sensing mechanism must be present in these instances to alert the cell to imminent danger, and to set in motion the orderly sequence of events that will mitigate this danger. The
      responses of genomes to unanticipated challenges are not so precisely programmed. Nevertheless, these are sensed, and the genome responds in a descernible but initially unforeseen manner.

      She ended her address this way

      quote :

      In the future attention undoubtedly will be centered on the genome, and with greater appreciation of its significance as a highly sensitive organ of the cell, monitoring genomic activities and correcting common errors, sensing the unusual and unexpected events, and responding to them, often by restructuring the genome. We know about the components of genomes that could be made
      available for such restructuring. We know nothing, however, about how the cell senses danger and instigates responses to it that often are truly remarkable.

      (my emphasis)
      http://www.nobelprize.org/nobel_prizes/ … ecture.pdf
      It was also her foresight was actually quite remarkable.

      For instance here then is an interesting review of some genomic changes(variations) found in nature. (1 December 2010)
      http://www.nature.com/nrg/journal/v11/n … g2883.html
      note what it says

      quote :

      Genomic rearrangements are associated with many human genomic disorders, including cancers. It was previously thought that most genomic rearrangements formed randomly but emerging data suggest that many are nonrandom, cell type-, cell stage- and locus-specific events. Recent studies have revealed novel cellular mechanisms and environmental cues that influence genomic rearrangements.

      (again my emphasis)
      I could ofcourse go on citing research after research paper endorsing these observations, if necessary.
      The point I make is this.

      The reality is that most genetic changes occur as a result of cellular processes in response to stress, damage and copying errors and are rectified in various ways, (I have not taken account of the developmental changes that occur) while most other mutations which for some reason not corrected, are deleterious to the organism.
      I haven’t even begun to talk about transposons and their part in genome restructuring. All these processes are under the control and regulation of the cell as it responds to stress and the maintaining of it’s own equilibrium.

      In the light of all this actual evidence (and with respect, not logic that you appear to rely upon) what does Natural Selection actually have to do?
      Where are the functional phenotypes that random mutation is supposed to have produced in order for NS to select from?
      It is no wonder that Darwin himself acknowledged he could recount no evidence for species change
      by NS.
      The reality is that NS has very eloquently described how species may survive but has nothing to say about how they arrived.
      Molecular biology was the great hope in answering the question of arrival, but it is only confirming
      what many have instinctively known, that this is not the answer.
      Neo darwinism is stuck in the Neanderthal period of last century biology and (I am sorry to be blunt about this) no amount of huffing and puffing is going to alter that. (I am not suggesting that you are doing this, but others certainly are)

      btw I use the term "evidently" meaning “According to the evidence available” a conclusion is drawn.

      I won’t go on to make this post any longer but I will continue with my response (i.e your third logic point that you feel is the most likely) in the next one.

    • #109977
      scottie
      Participant

      AstraSequi

      quote :

      Again, the possibilities are:
      – the mutations might be common enough that they happen all the time
      – the mutations might occur once or twice and then spread through the population by interbreeding
      – the mutations might have already been present in the ancestral population

      From my post above, I think it should be fairly clear that the third option is the most likely. However, even if it is incorrect, the others are still quite possible. 

      Sorry but the third possibility( the existing mutation) still has to deal with the actual issues of cell processes that researchers have identified and that I have already pointed to in my last post.

      I suppose most things are possible, it is possible that pigs will fly, but is that what we are discussing here, possibilities?
      I would argue not.

      quote :

      The interpretation “developed” is an inference that is not part of the data. Nobody has observed any population with no inversions. 

      Yes of course it’s an inference, that is what data does. It helps us to draw conclusions. Do not most research papers have a conclusion section.
      Also I have not made any statement about populations without inversions.

      quote :

      I will also point out that changes can indeed happen quite fast, so long as the environment also changes fast – it is mainly the major innovations (like fins turning into legs) that take large amounts of time. 

      You are right variations can happen quite fast.
      However what is the data for “fins turning into legs” Please remember that this is also an “inference” but from what data is that inference drawn?
      Darwin couldn’t find it in his pre molecular days, hence my question again, what has changed since then?

      The next part of your questions is a serious one that deals with probability theory so I will respond to that separately.

    • #109978
      Luxorien
      Participant
      quote :

      Where are the functional phenotypes that random mutation is supposed to have produced in order for NS to select from?

      I should think that the frame shift mutation that resulted in bacteria that could metabolize the byproducts of nylon manufacture would be an example of this. As would be the several mutations that seem to confer immunity to HIV. Or the mutation that causes sickle cell anemia (my favorite example of how relative the terms "beneficial" and "deleterious" are – it all depends on the environment). Or are you arguing that these mutations were non-random events controlled by transposable elements?

    • #109983
      AstraSequi
      Participant

      While I’m waiting for you to finish, I thought I would just clarify this:

      quote :

      Since you see no difference in the views I have presented, you have answered my question.

      Actually, I can’t figure out what the views you have presented are. I only said that among the statements that you quoted, I did not see anything contradictory to my own understanding of mutations and natural selection. (And of course, I only hold one viewpoint – the commonly accepted scientific one. :))

    • #109985
      wbla3335
      Participant
      quote AstraSequi:

      Actually, I can’t figure out what the views you have presented are.

      scottie has difficulty communicating but has just the one view: everything is programmed by his god. So everything that enters his brain has to pass through the god filter. But at least he’s learning, and education is a good thing. We can only hope that a day may come when, like looking at a Necker cube, everything will flip and he’ll get it.

    • #109991
      scottie
      Participant

      Luxorien
      Some parts of human population have a mutation to their hemoglobin. This is the protein in the red blood cell that carries oxygen. Often people from sub-Saharan African origins have two copies of this mutated gene, which leads to severe sickle cell disease.
      Individuals with that disease suffer quite badly
      However on the other hand, this trait is beneficial because it prevents the most severe symptoms of malaria, including death.
      Now is sickle cell a random mutation, we actually don’t know how it got into the human population but let’s assume that it is.
      Having two copies of the gene leads to severe sickle cell disease. Individuals with this disease suffer greatly.
      Untreated this disease often leads to death.
      http://www.ncbi.nlm.nih.gov/pubmed/14531921
      Does it prevent them from succumbing to malaria.?
      Well this trait can be beneficial to humans because it prevents the most severe symptoms of malaria, including death. 

      So the result is that people with this level of immunity from malaria because of carrying the sickle cell mutation are better off are they?
      Do they not still have the problem of sickle cell disease?
      And you refer to this as

      quote :

      (my favorite example of how relative the terms “beneficial” and “deleterious” are – it all depends on the environment)

      Try convincing a sufferer of sickle cell of the cleverness of these so called relative terms.

      The choice seems to be, suffer with malaria or sickle cell. I would call it being between a rock and a hard place for those unfortunate ones.
      What on earth is favourable about having to have sickle cell disease to prevent contracting malaria?
      Which way is Natural Selection working then?
      And finally this supposed to be your favourite argument for NS selecting from random mutations to produce new species is it?
      You need to try a bit harder.
      Now I will deal with your other points but please get in the queue, I am still dealing with the AstraSequi questions. But rest assured I will get back to you.

    • #109995
      scottie
      Participant

      AstraSequi
      (continued)

      quote :

      It depends what you mean by “unlikely.” While any individual mutation is unlikely, that doesn’t mean that it will not happen on a regular basis if you give it enough chances. 

      So the question therefore must be, how many chances does “enough” mean?
      (no need to answer 🙂 )

      quote :

      Suppose there is a mutation that has a one in a million chance of happening – you can call this unlikely. However, if a million fruit flies are born, then it will probably happen around once. If you then wait for a thousand generations, it will probably happen around a thousand times. 

      You are missing your own point here.
      The problem is that the second mutation has by necessity, have to build on the first for some fitness function to begin to arise.
      This is where your probability analysis falters.
      Your analogy refers to the same mutation arising. (the point you are making for your analogy)

      In order for an improved fitness/function to arise, the mutation must be different but also it has to add to the function of the previous mutation.

      The probability for every mutation, by nature of it’s randomness, has to start from scratch every time.
      So by your analogy of a thousand generations, the progressive mutation towards fitness/function will not occur around a thousand times. It will be orders of magnitude more.

      Also please remember that mutations are invariably deleterious to the organism.
      Take for example the mutation that causes Cystic fibrosis.
      As I understand it, this is a mutation caused by the deletion of three nucleotides. This is a fairly common mutation and deleterious, it is in the nature of most random mutations.

      For NS to select for survival or “fitness” whatever that should mean, the mutation needs to be a positive one. Now since most of these mutations are deleterious, any positive one, has to not only evolve for greater fitness or function, but it also has to offset the downward pull of the many harmful mutations that are also taking place.

      Your probability idea (although in terms of logic is possible) in reality is now far more remote than your simple calculation suggests.

      Another thing to please keep in mind, these examples of random mutations provide evidence of what is termed micro evolution and in a negative way at that, the deterioration of the organism. (Nobody as far as I am aware denies that these changes take place.
      The point is do these changes lead to new species formation.
      And this of course leads to another related question.
      What evidence do we have of the positive effects of any random micro evolutionary mutations?

      quote :

      (I will also point out that for a fruit fly, a thousand generations is only about 40 years.)

      I would ask, what evidence that the segmented nature of the body plan of the fruit fly has changed throughout it’s existence, regardless of how rapid its generation time may be.
      The body plan must be altered in some way for speciation to happen.

      Recall Richard Lenskie’s 22 year experiment with bacteria (I have covered this before). After over 50,000 generations in each of 12 populations (600,000 generations) no new species of bacteria arrived.

      quote :

      I think this might be an important point that you’re missing – in statistics, this is called a Bonferroni correction. If you roll a pair of dice, your chance of a double 6 is quite low (1/36). However, if you try twice, your chance doubles – and if you try a hundred times times, your chance of getting it at least once is very high – in fact, it would be more surprising if you didn’t get it at least once. The probability of something happening increases as the number of times it is possible to occur increases. 

      I don’t know much about the Bonferroni correction, but on what you appear to have indicated, there is an obvious flaw in trying to connect this with biological mutation.
      Your last sentence reveals the flaw.

      quote :

      The probability of something happening increases as the number of times it is possible to occur increases. 

      This is with regard to the same thing happening again and again.
      But for a new mutation to provide a positive outcome it must add to a previously positive one and in a positive way, to succeed. In other words ( as I have previously stated) it must be a different type of mutation.
      Take the cystic fibrosis mutation (the 3 nucleotide deletion), it can repeat itself over many generations in a population, but it is the same mutation.
      It doesn’t add anything.
      Also in addition to this one that I have cited, I am informed that there are some 200 other mutations of this gene that have been documented. So mutation of this gene is fairly common. Only a few lead to the severe form of this disease while others cause lesser problems, but, there are no beneficial results.

      Systems biologists are increasingly recognising the robustness of cellular processes. Mutations (of all kinds) produce little phenotypic variation. If the mutation is serious enough the organism either becomes diseased or it dies.

      Your roll of dice analogy simply does not apply.

      Finally on what is the “scientific” view of mutations? Are they all random or are they also non random.
      Let me answer since you appear to be somewhat coy over the subject. 🙂

      Mutations originate both randomly, and also as a result of cellular processes, non randomly.

      Actually the interjection by  Luxorien moves this subject on a bit as he raised an interesting side to this discussion.

      But before going on I am going to take a break.
      Be back in the morning UK time.

    • #110000
      Luxorien
      Participant
      quote :

      So the result is that people with this level of immunity from malaria because of carrying the sickle cell mutation are better off are they?
      Do they not still have the problem of sickle cell disease?

      No. They don’t. That’s the point: if you are heterozygous, you have no symptoms of sickle cell anemia and you have malaria resistance.

      The majority of mutations are neutral, with a few being harmful or beneficial. What this means is that there is a high degree of variation in sexually reproducing populations. This random element provides the fuel for the nonrandom action of natural selection. I guess I’m just confused as to how you can say that mutations are "invariably" harmful when there are copious examples of beneficial mutations, like antibiotic resistance in bacteria and HIV immunity in humans.

      The point of bringing up sickle cell anemia is to underscore how relative adaptations are. Whether a mutation is beneficial or neutral is almost entirely dependent on the environment. This means that a mutation which is neutral now may very well turn out to be useful in the future. There’s no predicting what might become advantageous later on. That’s why the key to species’ survival is random genetic variation. No matter what weirdness is going on with your environment, you have at least a chance of capitalizing on some beneficial tweaking of your DNA.

    • #110010
      scottie
      Participant
      quote :

      No. They don’t. That’s the point: if you are heterozygous, you have no symptoms of sickle cell anemia and you have malaria resistance.

      Actually they do have the symptoms of sickle cell, they just rarely develop the severe life threatening anemia typical of homozygous sicklers.

      It would help greatly if you appreciate what the sickle-cell trait actually is.
      It is often referred to simply as sickle-cell anemia. 
      However, the fact is, its a condition that creates many more medical problems than just anemia. 
      Victims of this trait are also likely to experience chronic complications involving their spleen, kidneys, heart, lungs, and immune systems. 
      Probably one of the most common symptoms is the persistent and agonizing pain caused by the deflated irregular shaped red blood cells blocking small blood vessels.
      So when the whole picture is appreciated it does not portray the rather simple situation you are suggesting.

      Additionally we do not know how this sickle trait appeared.
      You are just assuming it was a random happening.
      If it was it then could not be considered neutral could it? 🙂

      Now do you really want me to respond to all the other examples you have enumerated, because I can if you really wish to extend this periphery point.

      However you probably have not appreciated it, but you have just endorsed my entire point when you state

      quote :

      That’s why the key to species’ survival is random genetic variation.

      This is what I said on page 41 Sat Mar 03, 2012 5:23 pm

      quote :

      The reality is that NS has very eloquently described how species may survive but has nothing to say about how they arrived.

      So if you are going to debate NS how about addressing the question of arrival, because that is what NS is supposed to have accomplished and what this thread is all about.

    • #110039
      Luxorien
      Participant
      quote scottie:

      It would help greatly if you appreciate what the sickle-cell trait actually is.

      Sickle cell anemia is a recessive disorder caused by a point mutation on chromosome 11. The most common disease-causing mutation causes glutamic acid to take the place of valine in hemoglobin’s beta chains, which in turn causes a hydrophobic chunk to stick out of the protein, which in turn causes the proteins to clump together. Individuals who are homozygous recessive for the disease-causing variant are quite ill; individuals who are heterozygous, however, rarely experience symptoms. They still make sickle-shaped cells, but those cells generally do not cause them problems.You’re right to say that I’m simplifying things a bit. However, I don’t think I left out anything which would contradict the main point. The fact remains that most mutations are neutral, and that a mutation’s "value" is relative to environmental conditions.

      It seems you believe either that most heterozygotes have significant symptoms or that a small number of symptomatic individuals makes the heterozygote advantage irrelevant. As far as I can tell, the former is simply not the case. As for the latter, I don’t know what to say other than this: natural selection acts at the population level and only cares about reproduction, so a few individuals experiencing non-lethal symptoms will not outweigh the benefit of being malaria-resistant. If you survive to reproduce, you get to pass on your genes, even if your genes are suboptimal. Evolution doesn’t push organisms to be the best that they can be; it pushes them to be good enough. This is why so many people go around talking about "survival of the fitter" instead of "survival of the fittest."

      quote :

      Additionally we do not know how this sickle trait appeared.
      You are just assuming it was a random happening.
      If it was it then could not be considered neutral could it? 🙂

      We do know how it appeared: a mutation on chromosome 11. There are a couple hundred different ways this gene can get modified. These inadvertent modifications happen during DNA replication at a steady rate. It’s a chemical fact of the molecular machinery that runs organisms: mistakes get made. How harmful or beneficial those mistakes are depends largely on the environment.

      As for your claim that a random event can’t be neutral…I’m utterly perplexed. A random event is one that is not deterministic. A neutral mutation is one that is neither harmful nor beneficial (i.e. does not increase or decrease the organism’s chances of survival). There is no causal relationship between these two concepts. I have no clue what you are trying to say.

      quote :

      So if you are going to debate NS how about addressing the question of arrival, because that is what NS is supposed to have accomplished and what this thread is all about.

      One of the premises of your argument is that there are no "functional phenotypes that random mutation is supposed to have produced." I take "functional" to mean either beneficial or neutral. It sounds like you are arguing that a random process could not provide the variety and novelty necessary for macroevolution. Therefore, examples of beneficial point mutations are extremely relevant. But perhaps you meant to say something else.

    • #110059
      scottie
      Participant

      Luxorien
      Since you have not disputed my last statement that NS does not explain how species arrive I take it we are both agree in agreement. Is that a correct assumption?

      You are right in that sickle cell trait is an abnormality in Chromosome 11.
      However it is also brought about by diminished production of one of the two sub units in the hemoglobin molecule. Genic changes that produce this condition are termed thalassemias.

      There is a third condition that is brought about by abnormal association of sub units.
      The science of how these abnormalities came about is not known, despite your claim that it is.

      You will find that there are significant variations in hemoglobins.
      Here are some, Hemoglobin S, C, E, H,Constant Spring, and Barts.
      All these have different causes.

      Your hetrozygous condition that you claimed has no symptoms has in fact several, some of them resulting in conditions as serious as sickle cell disease.

      All these changes in the alpha or beta units have a deleterious effect, it is just that in one area the sickle trait provides a survival advantage over people with normal hemoglobin in regions where malaria is endemic, however sickle cell trait does not provide total protection nor invulnerability to the disease.
      Now just this brief summary shows the complicated nature of the sickle cell trait. To suggest that a simple mutation produces a beneficial trait for Nature to select from is simply incorrect.
      Regarding the term mutations.
      Many biologists regard all changes in genetic make up as mutations. Some are random errors/damage but the majority are not.
      Molecular Evolution makes this point
      http://www.tempoandmode.com/wp-content/ … oels08.pdf

      quote :

      All models recognize that most random changes to the genome are deleterious, because they will tend to disrupt highly organized genetic information. It is the relative proportions of mutations that are advantageous, neutral or nearly neutral that is debated.

      DNA replication is remarkably accurate. The DNA copying machinery in eukaryotes usually makes a mistake less than once in every million nucleotides. This incredible copy fidelity is achieved by a sophisticated error-checking system involving base selection, proofreading and postreplication repair.

      James Shapiro (evolutionary biologist) states

      quote :

      Genome restructuring is a normal part of cellular life

      http://shapiro.bsd.uchicago.edu/Shapiro … 0Dogma.pdf

      Now in case you are tempted to discard this biologist’s work as product of some sort of a lone wolf or other, just check out all the supporting citations in the paper, some 154 on total.
      Plus check out the various cell function responses to various stimuli in his table 1 page 16 -21,
      some 50 in all, as a start.
      Go to any source in epigenetics and you will read a similar appraisal. The genome is a fluid structure.
      There is no such thing as a static genome that is just subject to random changes. The vast majority of genome changes are as a result of cellular processes. These changes, you seem (if I understand you correctly) to think are what you call neutral mutations.
      The problem with that view is to show an example of a “neutral mutation” that is not part of a cell process. How many of these “neutral mutations” can you name?
      Your very example of the sickle cell trait reveals a structure alteration as part of the cellular process.

      All people have fetal hemoglobin in their circulation before birth. Fetal hemoglobin protects the unborn child and newborns from the effects of sickle cell hemoglobin. However this hemoglobin disappears within the first year after birth. Why?

      Is Natural selection at work in the unborn and new born selecting for survival, and then after about a year removes this survival package? How does that work?

    • #110065
      AstraSequi
      Participant

      Luxorien – I like your signature. 🙂

      Scottie – are you going to reply to the second half of my post? If you’re conceding points, I’d like you to specify that.

    • #110068
      Luxorien
      Participant
      quote AstraSequi:

      Luxorien – I like your signature.

      Thanks. I’m thinking of trying to convince my principal that this counts as "professional development." 😛

      quote scottie:

      Since you have not disputed my last statement that NS does not explain how species arrive I take it we are both agree in agreement. Is that a correct assumption?

      That is an incorrect assumption. I disagreed with one of the premises of your argument. It so happens I also diagree with your conclusion, though I suppose one does not necessarily follow from the other (though they often go hand in hand).

      quote :

      However it is also brought about by diminished production of one of the two sub units in the hemoglobin molecule.

      Hemoglobin is tetramer. There are four subunits: two betas and two alphas. The point mutation I referred to earlier causes the beta chains to be wonky. As I said, there are a couple hundred variants of this gene. Another mutation in that same location on chromosome 11 causes the beta thalassemias you seem to be talking about. The alpha chains can also get fooked by mutations in two genes on chromosome 16.

      I’m confused as to what all this has to do with the fact that heterozygotes have malaria resistance. What is your point here? That there are even more mutations that can confer malaria resistance?

      quote :

      The science of how these abnormalities came about is not known, despite your claim that it is.

      The genes that control the construction of the subunits have been located. Variants of these genes have been described. We know the exact substitution that occurs. People with certain variants have sickle-shaped cells. People with "normal" versions do not. What is mysterious about this? The DNA sequence changes, the protein changes, causing the observed phenotype. What exactly are you arguing? That the change in the single nucleotide was not the result of the sort of DNA copying errors that happen all the time in cells?

      quote :

      Your hetrozygous condition that you claimed has no symptoms has in fact several, some of them resulting in conditions as serious as sickle cell disease.

      I said that they rarely experience symptoms, and that their sickle-shaped cells generally do not cause them significant harm. The fact that a small percentage have symptoms is irrelevant. The majority of heterozygotes suffer no ill effects. And none of this has any bearing on the fact that these mutations confer malaria resistance, which is of clear benefit to the organism. It seems we have a dispute over a matter of fact.

      quote :

      Now just this brief summary shows the complicated nature of the sickle cell trait. To suggest that a simple mutation produces a beneficial trait for Nature to select from is simply incorrect.

      The most curious thing about your response is the way you zeroed in on the sickle cell allele and ignored other, more obviously beneficial, mutations. I mentioned sickle cell anemia as an aside, because I think it’s a cool example of heterozygote advantage. It’s incidental to the larger fact that some mutations increase an organism’s chance for survival. The sickle cell allele is just the best example of the crucial point that the environment often determines whether a mutation is harmful or neutral.

      quote :

      Many biologists regard all changes in genetic make up as mutations. Some are random errors/damage but the majority are not. Molecular Evolution makes this point.

      There is no semantic analysis of the words in that article which could lead to the conclusion that the authors regard mutation as anything other than a random copying error. Far from supporting your conclusions, this source directly contradicts everything you’ve been saying.

      The "Molecular Evolution" article discusses mutation rates, and how they may differ from one organism to another, or even between parts of the same genome. Changing the rate of mutation does not change the fact that a mutation is a random copy error. The article even mentions that "mutations occur spontaneously in every generation, but not all mutations become permanent features of the genome" (1). A spontaneous mutation is one that results from the random chance of a copying error when DNA is replicated.

      The authors go on to discuss the impact of selective pressures and genetic drift on the persistence of mutations: "For any given mutation, the chance of going to fixation (replacing the wild-type in the population) is dependent on the properties of both the mutation itself (its selection coefficient) and the population in which it arises (effective population size). These two things determine the balance between the two forces that shape substitution rates: selection and drift" (2). In other words, random copy errors get made, and the relative usefulness of those copy errors will determine whether they are quickly eliminated from the population, though genetic drift will play a part, especially in small populations. This article explicitly describes the very sequence you say is impossible: random mutation – positive selection for mutation – propagation of mutation throughout species – change in gene pool.

      Another section of this article deals with "the debate between neutralist and selectionist schools of thought" (3). This is right before the sentence you quoted. The existence of advantageous mutations is assumed, while, as you quoted above, "it is the relative proportions of mutations that are advantageous, neutral, or nearly neutral that is debated" (3). I’m confused as to why you think this article supports your claim that beneficial mutations do not exist, when the text clearly treats their existence as a fact. I suppose you think that their mention of the high rate of harmful mutations somehow validates your view. Maybe you’re arguing that the rates of mutation the authors mention are too low to produce advantageous mutations?

      I don’t see that this follows, either logically or experimentally. We can observe mutations happening in the lab. We can even make them happen more frequently in the hopes of snagging some mutations that are useful to us. It is a fact that random changes to DNA occur. It is also a fact that some of these changes will be deleterious, some will be neutral, and some will be beneficial. Even if we suppose that most mutations are harmful, the advantageous mutations whose existence you deny are still real. They still affect evolution.

      There’s another reason your article on molecular evolution contradicts your argument. It’s about molecular evolution. They are including in their calculations mutations that never make it to the organism level. From a molecular standpoint, most changes in DNA will be harmful. Hence the repair mechanisms. But if you sample populations, you’ll find mostly neutral variants, because harmful ones have already been eliminated by selective pressures. A few organisms will survive despite deleterious alleles, but most of the genetic variation we see at the population level does not affect an organism’s survival.

      Once again, this is highly relative. The terms neutral, deleterious and beneficial all depend on the environment. Additionally, rates of mutation are not constant and neither are selective pressures. As your article mentions, there are some portions of the genome that tolerate mutations more readily than others. So all of this is, to echo your own phrase, more complicated than the simple picture you’re trying to paint. That was my purpose is bringing up sickle cell anemia: the value of a mutation is relative to the environment. It is the presence of these three types of mutations and not their relative frequencies that makes evolution by natural selection possible. Even if only a tiny portion of mutations are beneficial, that’s enough genetic novelty to fuel speciation.

      Futuyma puts it this way: "The neutral theory acknowledges that many mutations are deleterious, and are eliminated by natural selection so that they contribute little to the variation we observe" (320, Evolutionary Biology). He’s discussing the same debate as the article you linked. This argument is about whether selection or drift affects molecular (not phenotypic, which is what you were talking about in your original post) variation. This (admittedly fascinating) scientific discussion has no direct bearing on phenotypic variations. It has more to do with improving the accuracy of our molecular clocks.

      I think maybe you’re trying to make a point similar to one I found in Evolution: The First Four Billion Years. It has to do with limitations on the possible forms that random mutation can produce. Brian Goodwin argues against the view that there is an "infinite diversity of possible forms for evolution to work with" (299). Instead, he contends that "there are constraints on the possible forms of organisms and their behavior, so that some forms can be generated, while others cannot" (299). This is not an argument against the ability of natural selection to produce new species. It simply points out that genetic variation is not unlimited. This fits with the common conception of natural selection as a force that works within certain ranges of possible change, modifying structures to perform new functions rather than creating new systems de novo.

      I suppose this might lead one to think that natural selection can change species but cannot produce new ones. The problem with that logic is this: it fails to recognize the incremental nature of evolution and speciation. Yes, there are limits on what natural selection can do, and it’s true that there are four other "forces" of evolution: genetic drift, migration, non-random mating and mutation. But given enough time, natural selection can produce enormous changes simply by moving in tiny steps. The "constraints" on variation do not prohibit the development of complex systems; they prohibit the rapid development of complex systems.

      quote :

      Now in case you are tempted to discard this biologist’s work as product of some sort of a lone wolf or other, just check out all the supporting citations in the paper, some 154 on total.

      I have already blathered on for way too long, so I’ll just address this briefly. For one thing, the number of citations in the paper is irrelevant to its scientific rigor and/or significance. The paper describing the discovery of the double helix, for instance, cites only four sources. So I’m not sure why you think that these 154 citations somehow make this paper irrefutable. I could write a paper hypothesizing the existence of pink unicorns and cite a hundred solid scientific sources; it wouldn’t make my conclusions true.

      The other thing I would mention is this: my concern with the "evidence" that you present is generally not that you are citing unscientific sources. Rather, I think you misunderstand and thus misrepresent the meaning and import of the sources you do cite. Your links often seem to have little bearing on the point you are trying to make. And, as we saw with the piece on molecular evolution, you often pick out contextless tidbits from texts that directly contradict you.

      quote :

      All people have fetal hemoglobin in their circulation before birth…

      None of the information in this paragraph or the next has anything to do with the existence of beneficial mutations.

    • #110072
      wbla3335
      Participant
      quote Luxorien:

      The other thing I would mention is this: my concern with the “evidence” that you present is generally not that you are citing unscientific sources. Rather, I think you misunderstand and thus misrepresent the meaning and import of the sources you do cite. Your links often seem to have little bearing on the point you are trying to make. And, as we saw with the piece on molecular evolution, you often pick out contextless tidbits from texts that directly contradict you.

      You’re relatively new to this thread. I’ve been around a bit longer but am tiring of banging my head against the wall. In case you haven’t delved too far back in the thread, I’ll fill you in on what you’re getting yourself into. Scottie is a creationist. I and others have tried explaining to him how science works, but he’s just not getting it. He’s not getting it because he’s a creationist. There’s something about early indoctrination that seems to close down certain brain functions. Scottie will cite reference after reference, completely ignore the intent of the authors of those references, and then provide his own interpretation that he thinks somehow supports the existence of his god. So, all the best to you.

    • #110075
      Luxorien
      Participant
      quote wbla3335:

      You’re relatively new to this thread. I’ve been around a bit longer but am tiring of banging my head against the wall. In case you haven’t delved too far back in the thread, I’ll fill you in on what you’re getting yourself into. Scottie is a creationist. I and others have tried explaining to him how science works, but he’s just not getting it. He’s not getting it because he’s a creationist. There’s something about early indoctrination that seems to close down certain brain functions. Scottie will cite reference after reference, completely ignore the intent of the authors of those references, and then provide his own interpretation that he thinks somehow supports the existence of his god. So, all the best to you.

      I have been going back through the earlier posts and trying to catch myself up. It’s quite a read. Thanks for the heads-up.

      I learned a lot about hemoglobin, mutation, molecular clocks, and genetic drift. I also have had the opportunity and impetus to read some interesting papers and books. So far this thread has been a success for me. 🙂

    • #110091
      scottie
      Participant

      Luxorien

      quote :

      “All people have fetal hemoglobin in their circulation before birth…”

      None of the information in this paragraph or the next has anything to do with the existence of beneficial mutations.

      Really
      Well my full statement reads

      quote :

      “All people have fetal hemoglobin in their circulation before birth. Fetal hemoglobin protects the unborn child and newborns from the effects of sickle cell hemoglobin. However this hemoglobin disappears within the first year after birth. Why?
      Is Natural selection at work in the unborn and new born selecting for survival, and then after about a year removes this survival package? How does that work?”

      May I remind you that it was you who introduced the sickle cell as a beneficial mutation, that NS has (non randomly)selected to protect against against malaria.
      So to ensure clarity of the point I raised.

      It is a fact that fetal hemoglobin protects the unborn child and newborns from the effects of sickle cell hemoglobin. Unfortunately, this hemoglobin disappears within the first year after birth.
      One approach to treating sickle cell disease is to rekindle production of fetal hemoglobin. The drug, hydroxyurea induces fetal hemoglobin production in some patients with sickle cell disease and improves the clinical condition of some people. (A non random process I am sure you will agree) 🙂

      So again my question is quite a simple one.
      If Natural Selection acting on random mutations is responsible for the fetal hemogoblin (which it has to be for the theory to be intact) and this hemogoblin protects against sickle cell, what is the process that removes this protection?
      According to your theory it can only be a random mutation(s). Is it not?
      So to get this straight.
      Random mutation first removes overall protection from sickle cell and all the problems that brings, then random mutation partially restores partial protection to offset a particular disease, and you regard this as a beneficial mutation?
      It is an interesting take on things, I’ll grant you that.
      Now I appreciate that this is an inconvenient fact that you may wish to ignore by claiming it’s irrelevance, but the question still remains.
      I asked the question not to seek an answer, because I knew that you couldn’t provide one, and you sadly have responded in the time honoured fashion, i.e. ignore that which contradicts a position.

      Now as regards Shapiro’s essay that you have so casually dismissed, a simple question.
      Point to any part of the science he refers to as being incorrect?
      His works is based on the work of Nobel Laureate Barbara McClintock.
      Are you equally dismissive of her work?

      As regards your lengthy response to the molecular evolution, I think that deserves a separate post.

    • #110093
      Luxorien
      Participant
      quote :

      May I remind you that it was you who introduced the sickle cell as a beneficial mutation, that NS has (non randomly)selected to protect against against malaria.

      Actually, I mentioned HIV immunity and antibiotic resistance as examples of beneficial mutations. I brought up sickle cell anemia as an interesting example of how the term beneficial can be relative. I said all this before, and you still keep talking about sickle cell anemia as though the existence of beneficial mutations stands or falls on this example.

      The simple fact remains that beneficial mutations exist. That is the only point that I am making. Your argument against the efficacy of natural selection relies on the premise that a random mutation cannot be beneficial. This premise is demonstrably false.

      quote :

      If Natural Selection acting on random mutations is responsible for the fetal hemogoblin (which it has to be for the theory to be intact) and this hemogoblin protects against sickle cell, what is the process that removes this protection?

      This argument fails on two levels. The first is that it assumes that fetal hemoglobin was originally produced throughout the life of the organism. This does not necessarily have to be true, and indeed is not true. So there was no protection that was subsequently removed. The second level at which this argument fails has to do with its relevance to the topic at hand. The fact that a single point mutation confers malaria resistance does not somehow go away because there is another mutation that can mitigate the effects of sickle cell anemia.

      To put it another way: instead of addressing the examples of beneficial mutations that were mentioned earlier, you keep piling on additional examples of what you think are features that natural selection could not have produced. I can explain why your example of fetal hemoglobin is not evidence against natural selection:

      <tangent>
      In the course of the (random) gene duplications that led to the present series of hemoglobin genes, certain sequences were positively selected for, or achieved fixation through genetic drift. A mutation in the fetal hemoglobin’s regulatory sequences can cause this hemoglobin to be produced throughout one’s life, but this mutation has not occurred often enough, or has not been selected for strongly enough, to become very common.

      There is no "protection" that originally existed that was selected against; fetal hemoglobin has always been produced during the fetal stage. It is possible that a mutation which causes this fetal hemoglobin to be produced throughout life could become quite common, but it doesn’t necessarily follow that this must happen. It depends on whether this (random) mutation happens often enough and in the right individuals. It depends on how many people with sickle cell anemia are successfully treated, and a bunch of other factors that would affect the strength of the selection pressure on this mutation.

      The theory of natural selection says that favorable variants will tend to increase in populations, but it does not say that every possible favorable variant must come into existence – that’s the random part of mutation.
      </tangent>

      But there is no point in doing so (responding to your additional examples of what you think are problems for natural selection) because you still have not demonstrated that the point mutations mentioned earlier (HIV resistance, antibiotic resistance, malaria resistance, nylon manufacturing waste metabolism) are anything other than random mutations that happened to be useful and were therefore selected for. As long as beneficial mutations exist (and they obviously do because we can literally watch this happen), your conclusions are invalid.

      You may want to argue that beneficial mutations are possible, but that they could not form complex systems because they don’t make big enough changes to the genome, or because a bunch of them would have to happen at once for a complex system to evolve. But arguing that beneficial mutations do not exist is like arguing that HIV does not cause AIDS.

      quote :

      Now I appreciate that this is an inconvenient fact that you may wish to ignore by claiming it’s irrelevance, but the question still remains.

      I will answer as many irrelevant questions as I have time to address, but they remain irrelevant. Whether the beneficial phenotype of being resistant to antibiotics is the result of a random mutation is a matter of fact which can be verified in the lab. Instead of addressing this, or even of addressing the fact that a single point mutation can confer malaria resistance, you are hunting around for other examples of mutation’s supposed failure to produce beneficial traits.

      Those examples can be discussed also, but discussing them will not negate your earlier failures to disprove the existence of beneficial mutations.

      quote :

      Now as regards Shapiro’s essay that you have so casually dismissed, a simple question.
      Point to any part of the science he refers to as being incorrect?
      His works is based on the work of Nobel Laureate Barbara McClintock.
      Are you equally dismissive of her work?

      As I said before, I do not necessarily question the scientific conclusions of the papers you cite. I question your ability to understand their meaning. As we saw earlier, you quoted from a paper that directly contradicts your argument. You went so far as to include in your quote a sentence that clearly stated that beneficial mutations exist. You ignored that sentence and bolded the part about most mutations being deleterious.

      I’m not sure why you keep asking me to point to flaws in their research. My argument has never been that they are bad scientists. My argument is that these papers don’t mean what you think they mean. You act as though the existence of transposable elements and epigenetics means that beneficial mutations don’t exist. Is that really your argument?

    • #110098
      AstraSequi
      Participant

      Scottie – in case you didn’t see my question above…

      quote AstraSequi:

      …are you going to reply to the second half of my post? If you’re conceding points, I’d like you to specify that.
    • #110129
      scottie
      Participant

      AstraSequi

      My apologies,
      Luxorien’s interjection somewhat hijacked me, quite challenge to deal with matters on different fronts. 🙂

      Anyhow I will return to you now, and ask Luxorien to be a little patient. I am sure he would appreciate the rest from parading his developmental potential to his principle. 🙂

      I believe you refer to your final point of your post of Sun Feb 19, 2012 12:08 am. Page 39
      My question was
      Has this situation changed since Darwin’s day?
      Can someone help with some evidence.
      Your reply

      quote :

      Most definitely. I suggest you read http://en.wikipedia.org/wiki/Speciation, and also any included citations if you want to investigate further. Please note in the opening paragraph, “Observed examples of each kind of speciation are provided throughout.”

      Thank you for the wiki reference, and I have studied it.
      It does provide good descriptions of the different kinds of speciation evolutionary theory posits.
      It goes on to exemplify this:-

      quote :

      One example of natural speciation is the diversity of the three-spined stickleback, a marine fish that, after the last ice age, has undergone speciation into new freshwater colonies in isolated lakes and streams.

       
      It provides a single reference in support of this, a 2000 paper.
      Historical contingency and ecological determinism interact to prime speciation in sticklebacks,
      Gasterosteus
      http://www.ncbi.nlm.nih.gov/pmc/article … 133026.pdf

      The first point I noted in the wiki discussion was, this example appears to be about variation within a species. Nobody as far as I am aware disputes that variation within a species does occur.
      However that said, the referenced paper does clearly state:-

      quote :

      Studies on the genetics, mate choice, ecology and morphology of these fish indicate that they are reproductively isolated and exploit alternative trophic niches in sympatry (Schluter & McPhail 1992; McPhail 1994;Taylor & McPhail 1999). Consequently, they fulfill the principal criteria of biological species. It has been well argued that ecological speciation, divergent selection
      involving exploitation of alternative trophic niches owing largely to resource competition, has been a major deterministic factor driving divergence in sticklebacks
      (McPhail 1993; Schluter 1994, 1996a,b; Rundle et al. 2000).

      So although they claim species divergence, they are still referred to three-spined sticklebacks (Gasterosteus aculeatus). I find that somewhat interesting.
      Be that as it may that is not all.
      In a more recent study found in the Journal of Fish biology we have this paper
      Along the speciation continuum in sticklebacks
      http://labs.fhcrc.org/peichel/media/pdf … 09_JFB.pdf
      The authors clearly depict their understanding of speciation, which again is quite clear.

      quote :

      Speciation involves the evolution of reproductive isolation among groups of individuals; isolation that is often coupled with genetic and phenotypic differences (Dobzhansky, 1937; Mayr, 1963; Schluter, 2000).

      The introduction states that speciation is a continuum of 4 different stages, with the final one being
      the complete reproductive isolation, and this reproductive isolation is always associated with chromosomal rearrangements and environment independent genetic incompatibilities.

      The paper then goes on to examine these 4 stages in connection with the stickleback.
      1) continuous variation without reproductive isolation
      2) discontinuous variation with minor reproductive isolation
      3) strong, but reversible, reproductive isolation
      4) strong and irreversible reproductive isolation
      Only stage 4 can be classified as a speciation event and the paper points to only one example

      It asks the question

      quote :

      Why have these sympatric pairs not proceeded to the point of irreversible reproductive isolation? One possibility is the limited time frame for their divergence, given that most freshwater populations were colonized from marine ancestors only after the last glaciation (Taylor & McPhail, 2000; Reusch et al., 2001; Makinen ¨ et al., 2006).
      Genetic incompatibilities (a possible route to complete isolation, see below) might take considerably longer to develop (Coyne & Orr, 2004; Bolnick & Near, 2005).
      This explanation is not entirely sufficient, however, given that genetic incompatibilities have not been documented across the range of G. aculeatus, including among populations separated for millions of years. A telling exception will be described below.

      Another possibility, then, is that the divergent selection is not strong enough to generate irreversible barriers through ecological speciation. Equivalently, assortative mating may not be strong enough, perhaps because trait divergence is not sufficient for females to reliably or profitably discriminate against heterospecifics. Finally, irreversible isolation in sticklebacks may require specific genetic changes, such as chromosomal rearrangements.

      The conclusion of this study has this to say

      quote :

      Finally, achieving state 4 (strong and irreversible reproductive isolation) seems to require additional factors, such as chromosomal rearrangements, intrinsic genetic incompatibilities and extended periods of allopatry, all of which are less obviously linked to processes occurring along the rest of the speciation continuum.
      Perhaps the greatest lesson that sticklebacks can reach is the value of plurality in the study of speciation. That is, speciation might often involve multiple and shifting geographic contexts and mechanistic drivers. This mosaic nature of speciation has also been suggested to characterize other taxa (Feder et al., 2005; Rundle & Nosil, 2005; Mallet, 2008; Nosil et al., 2009), and it might even be reasonably common in nature.
      The solution to Darwin’s ‘mystery of mysteries’ might therefore be considerably more complicated that proponents of parsimony might desire.
      Nature is not parsimonious.

      So the observed examples that wiki points to (stickleback) is not so observed after all, is it. 🙂

      The apparent necessity of Chromosomal rearrangements within the nucleus pose a significant problem, if speciation is the product of random mutations to the genome.

      We know the nucleus of each differentiated cell appears to possess an epigenetic mechanism.
      This mechanism regulates the position of each chromosome in the nucleus and thereby determines the way and timing of how expression takes place.
      We also know chromatin structure, the variation in histone 3D structure and so on are indeed regulated by this mechanism.
      So the control of chromosome activity in the nucleus clearly cannot be the product of a mutation in the genome.
      We are observing levels of information and control above and beyond genome information.
      All of these are not instigated or varied or regulated by mutations to the genome, and yet this study
      (which is very detailed and is really worth studying in full) is concluding that chromosome rearrangement is a requirement for speciation, whereas neo darwinian evolutionary theory is fixated on random mutations of the genome.
      Ones like Donald Forsdyke have long recognised this link between chromosomal arrangement and species specific traits, only to be castigated by the likes of Coyne and Orr with their gene centred views.

      So I conclude that despite the wiki appraisal of speciation as being a darwinian process, the evidence suggests no such thing.

    • #110132
      AstraSequi
      Participant
      quote AstraSequi:

      …are you going to reply to the second half of my post?
      quote scottie:

      I believe you refer to your final point of your post of Sun Feb 19, 2012 12:08 am. Page 39

      …Actually, no. I refer to the second half of my post, like I said in the question. I did not refer to one specific point near the end of my post.

      I am asking you for the fifth time to complete your response, or to concede points. Conceding points is not conceding the entire discussion, and I will not treat it that way. In fact, it will give the impression that you are a thoughtful person who is actually engaging seriously in the discussion. However, if you simply do not answer, that gives the impression that you are simply refusing to admit that you cannot. If you need time to think, then it would be polite to specify that. If you cannot respond and are still trying to maintain the same position without making any changes, I suggest that you ask yourself why that might be.

      Furthermore, please do not use responding to me as an excuse to avoid responding to Luxorien.

    • #110160
      Luxorien
      Participant
      quote scottie:

      AstraSequi

      My apologies,
      Luxorien’s interjection somewhat hijacked me, quite challenge to deal with matters on different fronts. 🙂

      Anyhow I will return to you now, and ask Luxorien to be a little patient. I am sure he would appreciate the rest from parading his developmental potential to his principle. 🙂

      No problem, man. I got time.

      I don’t understand any part of that last sentence except the pronoun, so I might as well take this opportunity to mention that I have girl parts. I don’t mean that as a reprimand – just stating a fact.

      Good luck.

    • #110185
      scottie
      Participant

      AstraSequi

      It seems to me that you are being quite evasive here.
      I believe I have responded to all the points you have made. If I have missed any then please be courteous enough to specify what I have not responded to.

      Also I have no intention of avoiding a response to anyone, nor have I even suggested that as an excuse. I will simply put your last comment down to a misunderstanding. 🙂

      It is noticeable to me that you have not responded yourself to the points I have raised in rebuttal. Are you then conceding those points?
      If not perhaps, could you in in turn address the issues I have raised.
      You do appear to be getting a bit rattled. 🙂

      Luxorien
      Sorry,
      Thanks for the gender correction.
      I have a very busy life at the moment and cannot devote all the time I would wish to this forum, so I appreciate your patience.

      I will go over your last post point by point as far as possible, and will start later on this evening.

    • #110191
      AstraSequi
      Participant

      I would call it frustration than being "rattled," thank you – it’s now been a month that I’ve been trying to get you to answer. If you were uncertain about anything, it would only have taken a couple of minutes for you to check, and I was assuming you could do that without me reposting it (although of course I would have, if you had asked). You were certainly able to find the comment about speciation which is within said post.

      I will, of course, start replying when you have finished. If I think I have points to concede, I will do so at that time. Since you say you have no intention of evasion, I will give you the benefit of the doubt, at least for now.

      The sections for which I see no response are as follows. If you actually did reply to any of it (besides the speciation comment containing the Wikipedia link, which I already know about), then please give me the page and post number.

      quote :

      quote :

      According to the theory, the mutations upon which this process rests is Random. To expect, as you suggest that changes will probably be in similar ways, is to support my view that the change is not random. You can’t have it both ways. Either change is random or it is not.

      This is essentially the same point. As long as you have enough chances, the “correct” mutations will be able to occur, and then natural selection will be able to act.

      For example, if we put some bacteria in nutrient-rich media, they will always start to grow faster after some time. This experiment only takes about a week to run, and the change will always be in the same direction.

      That is to say, we observe that natural selection produces the same result. This will happen for almost any bacteria we can grow – the new environment favors those bacteria that grow the fastest, so long as we allow enough time to pass.

      quote :

      Natural Selection is not a force but simply the naturally selected result of random forces.
      The driving force in darwinian theory is the random mutations that allow nature to select from.

      I think this is semantics. Both stages, the mutations and the selection, are required for species to adapt. If there are no mutations, no variation is generated and no change can occur. If there is no selection, only random change can occur.

      quote :

      The enviromental stress in three different continents are not the same. What the researchers noted was that the climate/latitude was the common factor. That is why they made the link with global warming.

      That is why I said:

      quote :

      In the most charitable interpretation I can think of, I suppose it is possible to make some assumptions and then say that their data is consistent with a completely deterministic model. However, you cannot say that it is evidence for such a model against natural selection, because natural selection can account for the same results quite well, and without the extra assumptions.
      quote :

      quote :

      Camille Parmesan at the University of Texas in Austin, US, who has carried out similar research, says these new findings are a warning that species may only have limited capacity within their own genomes to adapt to climate change.

      If the capacity for change is limited as this researcher warns, then what happens to the theory?
      After all climate has always been on the change throughout life’s history.

      Natural selection does not say that the capacity for change is unlimited. It might perhaps be the case, but only given enough time – the rate of change over any particular time scale is limited by the amount of pre-existing variation in the population, and the rate of production of new variation (that is, the rate of mutation).

      If the rate of change is too fast, the species is unable to adapt and goes extinct. Climate has never changed as fast as it is now in any point in Earth’s history (save perhaps the mass extinctions, and of course they didn’t go too well for life!)

      quote :

      quote :

      Are you sure you can’t think of another reason why someone would be disturbed by the observation that climate change is causing animals to undergo dramatic genetic changes?

      Well actually I cannot think of any reason why Dr Huey would be disturbed, other than this change does not sit well with evolutionary theory.

      Very well – it is related to what you said above. Drosophila is a highly successful species, with a very short generation time and the ability to adapt very quickly to new environments. When we see such a species changing very rapidly, it means that it needs to change that fast in order to stay adapted to the environment. (Or, in an even worse case, that its rate of change is at maximum, and it would be changing even faster if it could.)

      This means that any less successful species, which cannot adapt as fast as Drosophila is adapting now (and which does not have other options such as migration), is likely to be in great difficulty.

      In fact, I can tell you what the authors of the paper say, in their concluding paragraph:

      quote :

      The increasing numbers of examples documenting genetic (2–5, 8, 10, 11), as well as phenotypic (1, 2) responses, to recent climate change are not surprising from an evolutionary perspective, but nonetheless are disturbing from ecological or economic ones, because such changes signal inevitable disruptions in the distributions, population dynamics, and community interactions of organisms (1, 2).

      (My emphasis.)

      I definitely agree with you that the authors know more about this topic than us. However, you will then need to accept these statements as well. 🙂

      Also, observing rigorous data contradicting evolution would not be disturbing to scientists in the same way – it would be interesting.

      quote :

      Species change is the product of random (unguided with no goal) mutations with nature selecting any functional changes that present themselves.
      In other words the functional variation is already there for nature to select.

      I agree with your first statement. The second is not true in all cases, since mutations can and do continue to occur at about the same rate, whether selection is happening or not.

      In this case, the functional variation was indeed already there, and all three populations already had the capacity (a low level of pre-existing inversions) for that change, because they shared a common ancestor which already had that capacity, and none of them lost it in the intervening generations. I suppose you might call this “programmed,” insofar as all DNA is a cellular program, but there is nothing in this that contradicts natural selection.

      Actually – what do you mean when you say “programmed”? A definition might help to clear up any misunderstanding.

      quote :

      If the change is dramatic (as you are suggesting) then new species would be expected to arise.

      Speciation requires a) differential selection on different parts of the population, b) very low gene flow between those two parts of the population, and c) the low gene flow to be maintained until enough change has occurred to prevent any future interbreeding. (There are other types of speciation, but they are not as well understood.) The authors point out in the paper that criterion b is not met – in fact, that the gene flow is unusually high. As a result, criterion c cannot be met either.

      quote :

      Why would that be disturbing?
      Surely this is the natural way, according to the theory.

      As mentioned above – the authors say it quite well. Of course, it is not as disturbing for the future of life on earth as a whole, which will probably carry on no matter what we do.

      quote :

      What evidence is there for Speciation through Natural Selection?
      It is after all the corner stone of evolutionary theory.

      I would say the “cornerstone” is in fact the logical argument I mentioned above. (See below for my answer.)

      quote :

      Darwin’s own words
      http://www.jstor.org/pss/187407 (please note my good form in naming my source :))

      Thank you. 🙂

      quote :

      Has this situation changed since Darwin’s day?
      Can someone help with some evidence.

      Most definitely. I suggest you read http://en.wikipedia.org/wiki/Speciation, and also any included citations if you want to investigate further. Please note in the opening paragraph, “Observed examples of each kind of speciation are provided throughout.”

      quote :

      Lets try and make the question a little easier.

      What evidence is there that random mutations and natural selection can produce new functional biological information.

      This is not the same question. I will answer you if you can demonstrate that you understand why that is. 🙂

    • #110212
      scottie
      Participant

      AstraSequi
      This is going to be a long one, so take your time.

      quote :

      I would call it frustration than being “rattled,” thank you – it’s now been a month that I’ve been trying to get you to answer. If you were uncertain about anything, it would only have taken a couple of minutes for you to check, and I was assuming you could do that without me reposting it (although of course I would have, if you had asked). You were certainly able to find the comment about speciation which is within said post. 

      Yes you are right it has been a month, but what have you contributed in that time? What response have I had from you?
      However I don’t get frustrated, I have just learned to cope. 🙂

      quote :

      I will, of course, start replying when you have finished. If I think I have points to concede, I will do so at that time. Since you say you have no intention of evasion, I will give you the benefit of the doubt, at least for now. 

      Now now, I don’t need you to give me the benefit of any doubt, whether you harbour any doubts really is your concern.

      quote :

      The sections for which I see no response are as follows. If you actually did reply to any of it (besides the speciation comment containing the Wikipedia link, which I already know about), then please give me the page and post number. 
      According to the theory, the mutations upon which this process rests is Random. To expect, as you suggest that changes will probably be in similar ways, is to support my view that the change is not random. You can’t have it both ways. Either change is random or it is not.

      This is essentially the same point. As long as you have enough chances, the “correct” mutations will be able to occur, and then natural selection will be able to act.

      I would have thought my response on the wiki link along with the probability point was sufficient to answer most of your questions, but it seems not, so I will deal with all your points even though I will find myself going over the same ground again’

      So, how many “chances” are enough? And what are “correct” mutations.
      The “Chances” question can only be answered with probability theory. I have already dealt with that aspect of this subject see scottie » Sun Mar 04, 2012 7:42 pm page 41

      The question of “correct” mutations being random makes no sense when we are dealing with for example proof reading. This type of process requires some template to compare with in order to be “correct”.
      How about checkpoint systems during cell division. Here again there must be some template by which the process is able to determine when the process is ready to move on to the next stage.
      In other words there must be some body plan by which these mutations can be compared in order to make any determinations as to whether to continue or abort.
      No one as far as I am aware has even adequately addressed the how cell differentiation can be the result of random mutations to the genome.

      quote :

      For example, if we put some bacteria in nutrient-rich media, they will always start to grow faster after some time. This experiment only takes about a week to run, and the change will always be in the same direction.

      That is to say, we observe that natural selection produces the same result. This will happen for almost any bacteria we can grow – the new environment favors those bacteria that grow the fastest, so long as we allow enough time to pass. 

      The question is not whether the bacteria grow any faster, the question is does this produce any new species.
      The Lenskie experiment has clearly shown that no new species has emerged despite all the mutations that occurred.
      May I refer you to the previous discussions on this subject
      about14351-60.html
      Page 6  scottie » Mon May 02, 2011 7:10 pm
      For a start there has not been enough time in earth’s history for any probability theory to be used in connection with these ideas.

      quote :

      Natural Selection is not a force but simply the naturally selected result of random forces.
      The driving force in darwinian theory is the random mutations that allow nature to select from.

      I think this is semantics. Both stages, the mutations and the selection, are required for species to adapt. If there are no mutations, no variation is generated and no change can occur. If there is no selection, only random change can occur. 

      This is not about semantics. Random Mutations are the driving force in Darwinian processes. The problem is that you have to rely on such vague terms as “enough chances” to try and justify the hypothesis.

      quote :

      The enviromental stress in three different continents are not the same. What the researchers noted was that the climate/latitude was the common factor. That is why they made the link with global warming.

      That is why I said:
      In the most charitable interpretation I can think of, I suppose it is possible to make some assumptions and then say that their data is consistent with a completely deterministic model. However, you cannot say that it is evidence for such a model against natural selection, because natural selection can account for the same results quite well, and without the extra assumptions.

      Well you are right. You can suppose its possible to make any manner of assumptions if you wish to be charitable.
      It may not refute NS but it is certainly evidence against as I stated

      quote :

      Camille Parmesan at the University of Texas in Austin, US, who has carried out similar research, says these new findings are a warning that species may only have limited capacity within their own genomes to adapt to climate change.

      If the capacity for change is limited as this researcher warns, then what happens to the theory?
      After all climate has always been on the change throughout life’s history.

      Natural selection does not say that the capacity for change is unlimited. It might perhaps be the case, but only given enough time – the rate of change over any particular time scale is limited by the amount of pre-existing variation in the population, and the rate of production of new variation (that is, the rate of mutation).

      I haven’t suggested that NS in unlimited, however it is attributed with going from Amoeba to Man. That’s a very bold claim, so what is the evidence to back it up.

      quote :

      If the rate of change is too fast, the species is unable to adapt and goes extinct. Climate has never changed as fast as it is now in any point in Earth’s history (save perhaps the mass extinctions, and of course they didn’t go too well for life!)

      It’s not a question of whether the species goes extinct. Species do go extinct. The point is whether they change into new species, That is what Natural selection is supposed to accomplish.

      quote :

      Are you sure you can’t think of another reason why someone would be disturbed by the observation that climate change is causing animals to undergo dramatic genetic changes?

      Well actually I cannot think of any reason why Dr Huey would be disturbed, other than this change does not sit well with evolutionary theory.

      Very well – it is related to what you said above. Drosophila is a highly successful species, with a very short generation time and the ability to adapt very quickly to new environments. When we see such a species changing very rapidly, it means that it needs to change that fast in order to stay adapted to the environment. (Or, in an even worse case, that its rate of change is at maximum, and it would be changing even faster if it could.)

      This means that any less successful species, which cannot adapt as fast as Drosophila is adapting now (and which does not have other options such as migration), is likely to be in great difficulty.

      In fact, I can tell you what the authors of the paper say, in their concluding paragraph:
      The increasing numbers of examples documenting genetic (2–5, 8, 10, 11), as well as phenotypic (1, 2) responses, to recent climate change are not surprising from an evolutionary perspective, but nonetheless are disturbing from ecological or economic ones, because such changes signal inevitable disruptions in the distributions, population dynamics, and community interactions of organisms (1, 2).

      (My emphasis.) 

      I am aware of their “ not surprising from an evolutionary perspective” view but are they speaking from the perspective of speciation? The fact is they are not. The variations they are referring to are variation within species that appear to be governed by cellular responses to climate change. If natural selection was at work (in other words if NS was causing these changes) why would they be disturbing?
      After all is it not expected that natural selection will result in changes such as these.
      They are disturbing because they don’t sit very well with Natural Selection expectations.

      quote :

      I definitely agree with you that the authors know more about this topic than us. However, you will then need to accept these statements as well.

       
      I accept their data not their “disturbing” perspective.

      quote :

      Also, observing rigorous data contradicting evolution would not be disturbing to scientists in the same way – it would be interesting.

      So scientists are now relying on symantics are they?
      You are going around in circles here 🙂 How then did the program arise?

      The common ancestor argument is an assumption. The creationists argue that the data this argument rests on is equally applicable to the creation argument. So this is no different to the “God did it argument” except in your case you are only moving the problem back.
      The method by which the common ancestor arrived is no different to how  Drosophila arrived.
      Ernst Mayr one of the fathers of the Modern Synthesis in his Crafood Lecture put it this way.
      http://www.biologie.uni-hamburg.de/b-on … luence.htm

      quote :

      A most important principle of the new biological philosophy, undiscovered for almost a century after the publication of On the Origin of Species, is the dual nature of biological processes. These activities are governed both by the universal laws of physics and chemistry and by a genetic program, itself the result of natural selection, which has molded the genotype for millions of generations.

      According to Mayr, God didn’t do it. Natural Selection is what did it via common ancestory. That was his philosophy as he himself has put it.
      But you eventually get back to the single cell. He provides no explanation any more than Darwin himself did.
      How did the cell emerge? There is no plausible answer that scientists can envisage other than by some outside agency.
      My argument is simple. The same process that caused the cell to emerge is the one that has caused the different species to emerge and that is by an outside agency.
      Craig Venter has shown that an outside agency (his team) have managed to demonstrate proof of concept. Albeit not in the creation of life but how an existing life form can be changed by design.

      However In his intellectual arrogance Ernst Mayr classically contradicted his own argument.
      His philosophy as he states it, is “governed both by the universal laws of physics and chemistry by a a genetic program (his words).
      Every scientist knows that a program be it genetic or otherwise does two things.
      1) It uses natural forces which are governed by universal laws
      2) It injects decision nodes into the process to over ride that natural progress and directs (governs) towards a specified goal.
      He then goes on to state as if it were a fact that it was natural selection that created this program.
      What decision node has natural selection injected into a process governed by the universal laws that has resulted in this genetic program?
      Natural Selection has to work on what is already there, that is why is regarded as a selective process.
      It does not create anything let alone inject decision nodes into any process.
      For example how is the genetic code(s) the result of natural selection. There is no answer yet according to Mayr and all those who follow his philosophy, natural selection has somehow done just that. It is a dogma nothing else.

      quote :

      Actually – what do you mean when you say “programmed”? A definition might help to clear up any misunderstanding.

      Yes I did use the term programmed. I am not alone am I?

      quote :

      If the change is dramatic (as you are suggesting) then new species would be expected to arise.

      Speciation requires a) differential selection on different parts of the population, b) very low gene flow between those two parts of the population, and c) the low gene flow to be maintained until enough change has occurred to prevent any future interbreeding. (There are other types of speciation, but they are not as well understood.) The authors point out in the paper that criterion b is not met – in fact, that the gene flow is unusually high. As a result, criterion c cannot be met either. 
      Why would that be disturbing? 
      Surely this is the natural way, according to the theory.

      As mentioned above – the authors say it quite well. Of course, it is not as disturbing for the future of life on earth as a whole, which will probably carry on no matter what we do.

      Your assumption is that climate change is man made. You appreciate that the debate around this is quite vigorous.  

      quote :

      What evidence is there for Speciation through Natural Selection? 
      It is after all the corner stone of evolutionary theory.

      I would say the “cornerstone” is in fact the logical argument I mentioned above. (See below for my answer.)

      Logic does not necessarily reflect reality as I have pointed out to you before. It can only be used if it is based on evidence, and with respect that is where your problem is

      quote :

      Darwin’s own words
      http://www.jstor.org/pss/187407 (please note my good form in naming my source )

      Thank you. 
      Has this situation changed since Darwin’s day?
      Can someone help with some evidence.

      Most definitely. I suggest you read http://en.wikipedia.org/wiki/Speciation, and also any included citations if you want to investigate further. Please note in the opening paragraph, “Observed examples of each kind of speciation are provided throughout.”
      Lets try and make the question a little easier.

      What evidence is there that random mutations and natural selection can produce new functional biological information.

      Well we are back to the Wiki argument which I have dealt with.

      This whole post has really been an exercise in futility as I have gone over the same ground before and with others, however I don’t get frustrated as this is the price one has to pay for dealing with what is essentially
      a philosophical position trying to pose as science. 🙂

    • #110213
      wbla3335
      Participant
      quote scottie:

      This whole post has really been an exercise in futility

      Finally. Something we can agree on. Have you ever looked into the extensive research on the origin and evolution of religion and the psychology of religious belief? Doing so might be more fruitful than continuing with your misunderstandings and misrepresentations of biological evolution.

    • #110221
      scottie
      Participant

      Luxorien

      quote :

      Actually, I mentioned HIV immunity and antibiotic resistance as examples of beneficial mutations. I brought up sickle cell anemia as an interesting example of how the term beneficial can be relative. I said all this before, and you still keep talking about sickle cell anemia as though the existence of beneficial mutations stands or falls on this example.

      You mentioned sickle as your favourite that is why I went on to analyse it in the way I did.
      I also said I am quite happy to respond to your HIV and antibiotic resistance examples as well if you wished, so I don’t “keep talking about sickle cell anemia as though the existence of beneficial mutations stands or falls on this example.”

      If you recall I wrote

      quote :

      Now do you really want me to respond to all the other examples you have enumerated, because I can if you really wish to extend this periphery point.

      I hope you are not deliberately trying to misquote me and introduce straw man arguments.
      My point was and is, if you wish to point to “beneficial examples” then keep them in the context they appear.

      quote :

      The simple fact remains that beneficial mutations exist. That is the only point that I am making. Your argument against the efficacy of natural selection relies on the premise that a random mutation cannot be beneficial. This premise is demonstrably false.

      This is what I wrote on page 41
       scottie » Sat Mar 03, 2012 5:23 pm

      quote :

      The reality is that most genetic changes occur as a result of cellular processes in response to stress, damage and copying errors and are rectified in various ways, (I have not taken account of the developmental changes that occur) while most other mutations which for some reason not corrected, are deleterious to the organism. I haven’t even begun to talk about transposons and their part in genome restructuring. All these processes are under the control and regulation of the cell as it responds to stress and the maintaining of it’s own equilibrium.

      (my emphasis)
      I have not argued as you are suggesting, since when does “most other mutations .. are deleterious” some how translate into, as you put it “the premise that random mutations cannot be beneficial”
      Perhaps rebutting what I actually say would be helpful

      Further My point

      quote :

      If Natural Selection acting on random mutations is responsible for the fetal hemogoblin (which it has to be for the theory to be intact) and this hemogoblin protects against sickle cell, what is the process that removes this protection?

      Your response

      quote :

      This argument fails on two levels. The first is that it assumes that fetal hemoglobin was originally produced throughout the life of the organism. This does not necessarily have to be true, and indeed is not true. So there was no protection that was subsequently removed.The second level at which this argument fails has to do with its relevance to the topic at hand. The fact that a single point mutation confers malaria resistance does not somehow go away because there is another mutation that can mitigate the effects of sickle cell anemia.

      Your first point is somewhat bizarre. Are you actually suggesting that fetal hemoglobin was not produced first?
      I would have thought it was obvious that fetal hemoglobin had to be produced first if as you claim sickle cell is a random mutation. What on earth was it a mutation of, if fetal hemoglobin was not there in the first place.
      (or have I missunderstood you somehow?)
      Your second point is also somewhat curious.
      Fetal hemoglobin actually protects against malaria, it is when that protection is removed as part of the development process, that children become exposed. So the mutation is initially deleterious and then some protection is offered in the hetrozygote.
      This is what I mean when I suggest that you report on these matters in context.

      And again I remind you that the whole point of this discussion is about NS being the process of speciation.

      You then go on :-

      quote :

      I can explain why your example of fetal hemoglobin is not evidence against natural selection:
      In the course of the (random) gene duplications that led to the present series of hemoglobin genes, certain sequences were positively selected for, or achieved fixation through genetic drift. A mutation in the fetal hemoglobin’s regulatory sequences can cause this hemoglobin to be produced throughout one’s life, but this mutation has not occurred often enough, or has not been selected for strongly enough, to become very common.

      What evidence do you produce, that the course of the (random) gene duplications is what led to the present series of hemoglobin genes?
      I understand the hypothesis you are presenting and trying to explain, however what evidence do you call on that shows these random mutations have in fact produced the “present series of hemoglobin”
      I appreciate you actually believe this, but you have to do more than state a belief if you are going to present it as a fact, and an empirical one at that.
      As indeed you believe what you further go on to say

      quote :

      Even if only a tiny portion of mutations are beneficial, that’s enough genetic novelty to fuel speciation.

      Again I appreciate you actually believe that, however you have to provide the evidence to support that statement if you are presenting it as having any empirical support? Are you able to do that?

      However we are all agreed on this point, as you put it, “

      quote :

      From a molecular standpoint, most changes in DNA will be harmful. Hence the repair mechanisms.

      ( well almost agreed I would add most random changes..)
      You appear not to have thought through the natural implications of the statement.
      If random and unguided mutations produce speciation and as molecular evolution puts it

      quote :

      DNA replication is remarkably accurate. The DNA copying machinery in eukaryotes usually makes a mistake less than once in every million nucleotides. This incredible copy fidelity is achieved by a sophisticated error-checking system involving base selection, proofreading and post replication repair.

      What has produced the incredible copy fidelity achieved by a sophisticated error-checking system involving base selection, proofreading and post replication repair.

      Are you seriously suggesting that this same process of a tiny portion of random and indeed unguided mutations has also produced the sophisticated error-checking, proofreading and post replication repair.
      Are you not aware that in order to proof read, or repair the entire process must have some template or body plan to check against.
      The rest of your rather long essay stands or falls on these statements if it to be empirically sound.
      From a philosophical standpoint it may come over as sound, but we are dealing with reality.

      Finally as regards Shapiro’s essay.

      quote :

      As I said before, I do not necessarily question the scientific conclusions of the papers you cite. I question your ability to understand their meaning. As we saw earlier, you quoted from a paper that directly contradicts your argument. You went so far as to include in your quote a sentence that clearly stated that beneficial mutations exist. You ignored that sentence and bolded the part about most mutations being deleterious.

      Actually Shapiro rejects neo darwinian or the standard hypothesis. His view is that there is a third way that is neither Darwinian nor ID. He calls it Natural Genetic Engineering.
      He is not able to explain how this cellular engineering actually got started except that it was not through some Darwinian process.
      Since you are not necessarily questioning the scientific conclusions of his paper, perhaps you better read it more carefully, because he is actually arguing against your clearly stated views.
      I do really understand the papers I cite.

      Now you bring up the Molecular Evolution quote I presented.
      You appear once again to be misrepresenting my position, and then arguing against that misrepresentation.
      This straw man argument is a debating tactic that you probably are aware of, but I hope you are not using it as a strategy.
      It is quite clear I did not quote from Molecular Evolution because I agreed with the premise of the paper, as it is clearly one that tries to explain evolutionary theory which I disagree with.

      That quote was in the context of what constituted a mutation, as not all mutations are random or randomly neutral if any change in genetic sequence is regarded as a mutation.
      Many biologists hold the view that any change in genetic information is a mutation.
      I quoted it to show that even evolutionary biologists recognise that most random mutations are deleterious to the organism. These researchers themselves recognise that and so do you, as I have previously shown.

      My whole point is really quite simple.
      I am arguing that it is the cell with it’s built in systems, that responds to the environment and not the other way around as you argue in the case for natural selection.
      Random mutations that the cell for some reason cannot correct, debilitate the cell’s response to that pressure.

      So to be clear, let me remind you of what I actually wrote as a direct quote from Molecular Evolution.

      All models recognize that most random changes to the genome are deleterious, because they will tend to disrupt highly organized genetic information. It is the relative proportions of mutations that are advantageous, neutral or nearly neutral that is debated.

      The question of what categorises a mutation is perhaps better left to another post.
      Do you wish me to respond to your HIV and antibiotic examples?

      May I request however before you feel the need to respond to any of my arguments please present an argument against what I actually write.

    • #110223
      AstraSequi
      Participant

      Thank you for the reply. I will reply in kind (for all of your posts, of course, not just the most recent one) by next week.

      In the meantime, I will point out:

      quote :

      Yes you are right it has been a month, but what have you contributed in that time? What response have I had from you? However I don’t get frustrated, I have just learned to cope.
      quote :

      Now now, I don’t need you to give me the benefit of any doubt, whether you harbour any doubts really is your concern.

      I think that anyone who reads the discussion since page 39 will see my responses. I suppose I assumed it was understood that I didn’t really want to reply until you had responded point by point, which I suppose I might have made clearer. (You appreciate that someone not arguing in good faith could take advantage of this to drop points they didn’t want to answer, not that I’m imputing this to you.)

      I would also like to mention that the quoted statements above came across as quite condescending. Of course I’m sure this was not your intent, and it doesn’t make much difference to me personally either way, but I thought I would let you know.

      I’d rather not comment on this again, since the issue is over now that you’ve finished the reply.

      Also,

      quote :

      quote :

      Actually – what do you mean when you say “programmed”? A definition might help to clear up any misunderstanding.

      Yes I did use the term programmed. I am not alone am I?

      is not an answer to the question.

      I know that you might think there is a standard definition, but if so please quote it to me. I think that your use of the word may not be what I am understanding from it.

      Finally, you seem to have left my final point out of your reply – I assume this is an oversight.

      The question was, do you understand the difference between speciation and production of new biological information? If so, please humour me and give an answer, since I think this might be an important point.

    • #110258
      Luxorien
      Participant
      quote scottie:

      I hope you are not deliberately trying to misquote me and introduce straw man arguments.
      My point was and is, if you wish to point to “beneficial examples” then keep them in the context they appear.

      I’m not sure what you mean by keeping things in "context." I guess you’re saying that any example of beneficial mutation is, in a sense, taken out of context because you think I’m not representing the full complexity of the issue?

      I agree that I left out a lot of detail, but as I said before, nothing I left out was relevant. You offered some assorted statements about sickle cell anemia that had nothing to do with the fact that sickle cell anemia is caused by a random mutation and that it does confer an advantage, albeit one that is highly situational.

      quote scottie:

      I have not argued as you are suggesting, since when does “most other mutations .. are deleterious” some how translate into, as you put it “the premise that random mutations cannot be beneficial”

      Since the statement I was responding to read as follows:

      quote scottie:

      Where are the functional phenotypes that random mutation is supposed to have produced in order for NS to select from?

      -March 3rd, pg. 41

      As I have said many times before, my only contention is that random mutations can produce beneficial mutations. Your statement from March 3rd appears to contradict that. Much of what you’ve said in response to my first post has been irrelevant to the question of whether there is such a thing as a random mutation that can produce an advantageous phenotype.

      In one of my previous posts I explained that I took your statement to mean that a beneficial mutation could not be produced randomly, and you neither confirmed nor denied this interpretation. Based on your most recent foray, it sounds like you wish to deny this interpretation. If that is the case, the prosecution rests. 😉

      quote scottie:

      Your first point is somewhat bizarre. Are you actually suggesting that fetal hemoglobin was not produced first?

      I think perhaps I did not make myself clear. Yes, I am actually suggesting that fetal hemoglobin was not produced first. But I’m talking on an evolutionary time scale, not during the life of a single organism. Our (reptilian) ancestors had normal adult hemoglobin before they had fetal hemoglobin.

      quote scottie:

      I would have thought it was obvious that fetal hemoglobin had to be produced first if as you claim sickle cell is a random mutation. What on earth was it a mutation of, if fetal hemoglobin was not there in the first place.
      (or have I missunderstood you somehow?)

      You have misunderstood me so severely that I’m unsure how to proceed. I’m not sure why it would be "obvious" that fetal hemoglobin was produced first if sickle cell is a random mutation. There is no logic in that statement. Fetal hemoglobin and adult hemoglobin are not produced by the same genes. A mutation in the gene that codes for adult hemoglobin will have no effect on fetal hemoglobin production. Nor will a mutation in fetal hemoglobin affect adult hemoglobin production. They are two separate molecules, with different structures. They are produced by different genes. There’s a good diagram of the gene clusters here.

      quote scottie:

      Your second point is also somewhat curious.
      Fetal hemoglobin actually protects against malaria, it is when that protection is removed as part of the development process, that children become exposed. So the mutation is initially deleterious and then some protection is offered in the hetrozygote.
      This is what I mean when I suggest that you report on these matters in context.

      I’m confused by this. Are you saying that the sickle cell mutation causes the cessation of fetal hemoglobin production? Are you arguing that the mutation is occurring as the child develops? I still don’t get what fetal hemoglobin has to do with anything.

      quote scottie:

      What evidence do you produce, that the course of the (random) gene duplications is what led to the present series of hemoglobin genes?

      Evolution by gene duplication is old news. As far as I know, researchers still regard the origin of hemoglobin clusters by duplication as a matter of fact. That article is not very recent, but it has the advantage of being available in full text for free. A search of more recent papers turns up a lot of abstracts that seem to treat this as a matter of course.

      I’ll stop there for now, because it’s almost time to go to work.

    • #110267
      wbla3335
      Participant
      quote Luxorien:

      Evolution by gene duplication is old news.

      Creationists have not managed to come up with viable arguments against the evidence for evolution, particularly for gene duplication, even more particularly for polyploidy, and most particularly for allopolyploidy (verging on the perverse). Maybe the creator had the hiccups or just ran out of ideas.

    • #110279
      JorgeLobo
      Participant

      Evolution has nothing to do with creation of life – only modification after the event.

      Science is not driven by "argument" and even if there were data generated that impeached the thery of evoluton, it would not de facto establish some religious concept as its replacement.

    • #110313
      AstraSequi
      Participant

      I’ve been thinking about the comments earlier, and I realized while writing it that the discussion has started to get less useful for me as well – not least because of how much time it’s taking (this reply took ~12 hours to make, including all the researching, and it is ~26 pages long in Word). As a result, I’ll make this my last response.

      However, I still suggest you read it carefully, and try to make sure you understand my points. If you have a few questions about the scientific content, I can probably still find some time, but try to make sure you actually understand what the question is first and have tried to understand the scientific opinion on it (for example, on Wikipedia or TalkOrigins, or in a science textbook). Of course, when looking for evidence, I would suggest you make sure you understand this link as well: http://en.wikipedia.org/wiki/Confirmation_bias. 🙂

      Anyways, I hope this is useful to you. I have divided up my discussion into posts based on how you divided yours ‒ approximately 1:1, but I split a couple of them for consistency of post length.

      quote scottie:

      quote :

      Then what is your objection?
      The occurrence of natural selection is based on a logical argument, with four premises. (Can you reconstruct the argument?)
      – the offspring of animals are never exactly the same as their parents, but rather have small variations.
      – some of this variation gives an advantage to an animal that possesses it
      – these variations can be passed down to the next generation
      – in each generation, not all animals survive.

      If you wish to dispute the occurrence of natural selection, you have to deny one of the premises.

      I understand the logic of the argument and I have no problem with it.
      This logic is perfectly acceptable.
      The problem is in how the variation arises.

      Yes, but the fact that variation does arise is the important point (and it is very easy to observe). The mechanism by which it occurs is irrelevant to the original argument. It turned out that the mechanism was mutation, but their discovery only strengthened the original argument instead of being required for it.

      So just to be clear (since you have “no problem with it”), you agree that natural selection occurs, and that changes occur in species over time as a result?

      Remember, if you want to say that change does not occur, you must say that one of the four premises is false. Again – can you reconstruct the argument? If so, please humour me and demonstrate your understanding.

      quote :

      However I believe the question of definitions is important here.

      So, to understand NS is it not first necessary to get clear what a mutation is and then determine how it is regarded as random, because it appears according to berkley edu, that all genetic variations are random.

      What a mutation actually is, needs to be determined, since there are those who have a different description of mutations.

      Again, the appearance of genetic variation is random, and natural selection is not random. The two are separate processes; natural selection acts only after the genetic variation is generated.

      The first process is random, and the second is not. This means that after natural selection, the variation within the population is also not random, although it is constrained by what the first process generates.

      I apologize if you already understand this, but I don’t see what it is that you’re not getting.

      You gave these three descriptions:

      quote :

      The genetic variation that occurs in a population because of mutation is random-but selection acts on that variation in a very non-random way: genetic variants that aid survival and reproduction are much more likely to become common than variants that don’t. Natural selection is NOT random!
      quote :

      The term mutation can refer to any process that changes the genetic information in the genome, including DNA insertions, deletions and rearrangements.
      quote :

      Genetic variation is generated continuously by the mutational process, but its persistence in the genome is determined by different historical and genomic factors.

      …and you said that the first contradicted the other two. As I already mentioned, I see nothing in any of these quotes which implies any contradiction between them, or with my own understanding of mutations or natural selection. Again, it would be helpful if you could specifically identify what you think the contradiction is.

      I would also point out that of the three quotes, only the second is actually a specific definition – the others are descriptions. For example, the only thing the third description really implies about mutations is that they continuously generate genetic variation.

      If you go to the Berkeley website and look at their definition of mutations (the quote you have taken is from their natural selection page), you get this definition:

      quote :

      Mutation is a change in DNA, the hereditary material of life.

      Again, I don’t see the contradiction. The second of your quotes is somewhat more advanced, referring to the process causing the change rather than the change itself, but the end result of what the DNA sequence is afterwards is the part that is relevant to natural selection.

      quote :

      Also when berkley edu sets out to describe what a Random mutation is, notice what it states

      quote :

      Mutations are “random” in the sense that the sort of mutation that occurs cannot generally be predicted based upon the needs of the organism.

      So therefore, before a mutation can be classified as random or not, (although berkley seems to suggest that all mutations are random) we have to determine what the needs are of the organism. How then is that achieved?

      Mutations are random. Some kinds are more likely than others (sometimes much more likely, as you correctly point out below), and there are also some things that can cause mutations with very high probability (like UV light). However, there is no guarantee that any particular mutation will be observed.

      The “needs” of the organism are only important in the second stage, natural selection. So I suppose that if you constrained “mutation” to refer to only the changes that persisted in the population, then you would only see those which corresponded to the “needs” – that is, the beneficial ones (or at least, the ones that are not detrimental) – because otherwise they would have disappeared.

      Is this what the misunderstanding is? If you observe a mutation that has spread within the population, then it is highly likely to be beneficial. That doesn’t mean that all mutations are beneficial, because natural selection filters them (we don’t see any mutations that caused the animal to die as an embryo, for example).

    • #110314
      AstraSequi
      Participant
      quote scottie:

      So can we agree on what each of us means when we use the term mutations. As I have demonstrated there are differing views on what constitutes a mutation.
      The talkorigins essay by Richard Harter states that :-

      quote :

      It is important to realize that mutations do not occur in response to the environment. They simply happen.

      This appears to agree with berkley edu.
      I have given you my understanding, could you let me know what your understanding is, so at least we don’t get to talk across each other.

      Again, I see no contradiction. I would add that some environmental factors can change the mutation rate (for example, exposure to UV light), but these are exceptions.

      What I am describing (which you could call my "understanding," I suppose) is detailed above. Let me restate it as a specific example:
      – Suppose a polar bear has a fur coat of a certain length, which is optimized to its conditions (too long and the bear will overheat, too short and it will freeze).
      – Mutations are always happening, some of which will result in longer fur and some of which will result in shorter fur. However, these are suboptimal, so polar bears with these mutations don’t survive very well, and the mutations don’t get passed on.
      – Now suppose the environment changes to become colder. The new optimum fur length is longer than the current length of the population.
      – The next time a longer-fur mutation happens, that polar bear will survive. In fact, it will survive better than the polar bears without the mutation. Shorter-fur mutations continue to happen, but continue to be maladaptive – in fact, they now confer more of a disadvantage.
      – As a result of the longer-fur advantage, the longer-fur mutants will leave more offspring.
      – Since this applies to the polar bear’s descendents as well, the longer-fur mutants will eventually take over the population.

      Also, if there was another population where it didn’t get colder, then those polar bears would not change their fur length. The two populations would then have a difference between them, and sufficient differences would result in speciation. In fact, if polar bears were like certain birds and females were most interested in males that had the same fur length as themselves (this is called assortative mating), then this one change could be sufficient for speciation.

    • #110315
      AstraSequi
      Participant
      quote :

      There are random mutations that rearrange the DNA of the cell. These mutations are invariably the result of copying errors, breakdown in regulating functions like error correction, and DNA damage from environment like from chemical or UV radiation sources.

      I agree, although I will point out that not all mutations rearrange the DNA – some of them just change it.

      quote :

      There are also more mutations in DNA, by orders of magnitude, as a result of regulated cell processes, than those that are random in nature.

      Some mutations occur as byproducts of regulated cell processes, yes. For example, DNA synthesis is not perfect and introduces errors. That does not make the errors non-random – there is no way to predict where specifically the DNA polymerase enzyme will make a mistake.

      A cell undergoing DNA synthesis is more likely to undergo a mutation than a cell that is not, but that is just a shift in the probabilities.

      quote :

      Barbara McClintock described various ways that an organism uses to respond to stress, among them by altering its own genome.

      quote :

      Some sensing mechanism must be present in these instances to alert the cell to imminent danger, and to set in motion the orderly sequence of events that will mitigate this danger. The
      responses of genomes to unanticipated challenges are not so precisely programmed. Nevertheless, these are sensed, and the genome responds in a discernible but initially unforeseen manner.
      quote :

      She ended her address this way

      quote :

      In the future attention undoubtedly will be centered on the genome, and with greater appreciation of its significance as a highly sensitive organ of the cell, monitoring genomic activities and correcting common errors, sensing the unusual and unexpected events, and responding to them, often by restructuring the genome. We know about the components of genomes that could be made available for such restructuring. We know nothing, however, about how the cell senses danger and instigates responses to it that often are truly remarkable.

      (my emphasis)
      http://www.nobelprize.org/nobel_prizes/ … ecture.pdf

      Yes, a cell under stress conditions might increase its mutation rate, including the rate of “restructuring” events such as inversions and translocations. This allows a greater diversity in the progeny, increasing the chance that some may survive. This does not imply that the mutations have become non-random.

      I don’t know whether this has been shown definitively – this is not a peer-reviewed publication, after all (it is speculation, of which lectures often contain a lot – and is about 30 years old, far out of date). However, it makes logical sense – it might even be possible that some types of mutation are more likely to produce adaptations to certain kinds of stress, and these specific types of mutation are induced.

      I will also point out that if you search for “restructuring” within the document, you will find her talking about it as something that occurs during species transitions.

      quote :

      For instance here then is an interesting review of some genomic changes(variations) found in nature. (1 December 2010) http://www.nature.com/nrg/journal/v11/n … g2883.html
      note what it says

      quote :

      Genomic rearrangements are associated with many human genomic disorders, including cancers. It was previously thought that most genomic rearrangements formed randomly but emerging data suggest that many are nonrandom, cell type-, cell stage- and locus-specific events. Recent studies have revealed novel cellular mechanisms and environmental cues that influence genomic rearrangements.

      (again my emphasis)

      Firstly, given that the paper is talking almost exclusively about genomic rearrangements that occur in cancer, I don’t think this helps you claim that these rearrangements are beneficial.

      That being said – yes, mutations often do not form completely randomly, and can be highly influenced by the situational context. Sometimes, the influence is enough that you might call them “nonrandom,” at least with respect to certain parameters. This does not make them predetermined (that is, nonrandom with respect to every parameter), as you seem to be arguing. For example, meiotic crossing over is essentially a series of translocations, and they are nonrandom in that they only occur in a very specific circumstance, but the locations where it occurs cannot generally be predicted.

      The changes are not random if you say that “random” means that every outcome is equally likely. If you think that is a potential confusion, it is probably better to call mutations probabilistic. There is another explanation of this at http://www.talkorigins.org/origins/post … 11_01.html.

      quote :

      The reality is that most genetic changes occur as a result of cellular processes in response to stress, damage and copying errors and are rectified in various ways, (I have not taken account of the developmental changes that occur) while most other mutations which for some reason not corrected, are deleterious to the organism.

      If you want to say this, you will also require evidence supporting the use of the word most in your first sentence.

      You should also be aware that only germline genetic changes are relevant to natural selection. Changes that occur in somatic cells, which involve most types of environmental influences (including those that lead to almost all cancers) do not affect the next generation.

      quote :

      I haven’t even begun to talk about transposons and their part in genome restructuring. All these processes are under the control and regulation of the cell as it responds to stress and the maintaining of its own equilibrium.

      For the context of natural selection, transposons are just another way that genetic changes occur – and yes, in some cases they are not entirely random. For example, I think there is research showing that transposon activation in humans is more common in the germline. I’m not sure why you think they would be any different from other mutations with respect to the discussion though.

      quote :

      In the light of all this actual evidence (and with respect, not logic that you appear to rely upon) what does Natural Selection actually have to do?

      Are you suggesting that cells intrinsically have a general capability to adapt genetically to environments without (random) mutation? It is quite easy to design experiments that falsify this.

      For example – take a cell, form several clonal populations from it – so the populations are identical except for random changes. Expose them to stress, enough to slow their growth but not enough to kill them off. If they have a programmed response, they will all respond in the same way and at the same time. Your readouts will be the rate of growth (all of them should increase in growth rate at the same time, as they all adapt in the same way) and the DNA sequence (all of their genomes should have changed in the same way). This can be repeated with many different kinds of stress.

      Or you could take some of those clonal populations and cause them to have a higher error rate in DNA synthesis. (Probably by addition of certain mutagens, or knockout/inhibition of a repair enzyme.) If the result is programmed and has nothing to do with the error rate, then the cell will again adapt to the stress in exactly the same way as the other cells (or possibly even worse). If the increased mutation rate is beneficial, as would be expected by natural selection, the higher-error cells will adapt faster.

      Do you agree that these are reasonable and fair tests? If you’re interested in science, you could probably think of even more ways to investigate. 🙂 Of course, these or similar experiments were already done many decades ago, and were shown to be in favour of natural selection. You may, of course, repeat them for verification if you choose – the ability to do that is part of what makes science unique.

      quote :

      Where are the functional phenotypes that random mutation is supposed to have produced in order for NS to select from?

      Answers have already been provided. For example, one such phenotype is the behaviour of hemoglobin containing the sickle-cell mutation.

      quote :

      It is no wonder that Darwin himself acknowledged he could recount no evidence for species change by NS.

      I think you need to provide a quote – taken in context, of course. For example, the Galapagos finches are different species.

      Also, if I recall correctly, most of the arguments and evidence involved showing that speciation through natural selection was plausible and not the only possible explanation. I am willing to be corrected though.

      You should also remember that the evidence available to Darwin was far less than the evidence available today, and it is unsurprising that there were some things he could not explain. Even if Darwin did not have evidence for something (for example, the fossil record was extremely poor in his time), that does not mean the evidence does not exist today.

      quote :

      The reality is that NS has very eloquently described how species may survive but has nothing to say about how they arrived. Molecular biology was the great hope in answering the question of arrival, but it is only confirming what many have instinctively known, that this is not the answer.
      Neo darwinism is stuck in the Neanderthal period of last century biology and (I am sorry to be blunt about this) no amount of huffing and puffing is going to alter that. (I am not suggesting that you are doing this, but others certainly are)

      This is basically an assertion that speciation cannot occur, followed by a claim that evolutionary theory is out of date (relative to what?). I’m not sure what this adds to the discussion. 🙂

      Of course, evolutionary theory has indeed advanced continuously, and the topics we are discussing have been known to biologists for some time. However, it is knowledge which has not been overturned to date. Some nuances have been determined (some of which you are clearly aware of), but the broader picture remains.

    • #110316
      AstraSequi
      Participant
      quote :

      quote :

      Again, the possibilities are:
      – the mutations might be common enough that they happen all the time
      – the mutations might occur once or twice and then spread through the population by interbreeding
      – the mutations might have already been present in the ancestral population

      From my post above, I think it should be fairly clear that the third option is the most likely. However, even if it is incorrect, the others are still quite possible.

      Sorry but the third possibility (the existing mutation) still has to deal with the actual issues of cell processes that researchers have identified and that I have already pointed to in my last post.

      I told you why I didn’t want to suggest which one I thought was most likely – because you would immediately talk about only that one, and ignore the other two.

      Again, all three possibilities are plausible, and there are probably more that I haven’t thought of. If you say that there is no plausible example, and three counterexamples are presented, addressing one counterexample is not sufficient.

      Furthermore, I don’t know exactly what you’re referring to by saying “issues of cell processes,” so I don’t know how to address your response. (Presumably it is something I replied to above.)

      quote :

      I suppose most things are possible, it is possible that pigs will fly, but is that what we are discussing here, possibilities? I would argue not.

      Well, you are arguing that certain things are not possible, right? Don’t you think that the evidence presented by someone replying to such a claim (X is not possible) would involve showing that X is possible?

      Speaking of which, I don’t think you’ve clearly identified exactly what it is that you think is not possible – or at least, there are a number of things you think are not possible, but I can’t tell which is/are central to your argument, and a couple of them are also contradicted by some other things that you’ve said.

      When I say central, that means the following – the things which, if you agreed were possible, would mean that you would also agree with the commonly accepted scientific view of evolution.

      quote :

      quote :

      The interpretation “developed” is an inference that is not part of the data. Nobody has observed any population with no inversions.

      Yes of course it’s an inference, that is what data does. It helps us to draw conclusions. Do not most research papers have a conclusion section. Also I have not made any statement about populations without inversions.

      You are the one who said that the inversions “developed.” Your quote: page 39, post 1.

      quote :

      Please note that three separate populations on three different continents developed these same inversions and in an “evolutionary” short space of time.

      I can’t see any way to interpret this statement other than that they were not present, and then they were.

      Also, the inferences are normally presented in the Discussion section. The conclusion restates the major inferences and speculates on what the importance might be if the inferences are true.

      quote :

      You are right variations can happen quite fast. However what is the data for “fins turning into legs” Please remember that this is also an “inference” but from what data is that inference drawn? Darwin couldn’t find it in his pre molecular days, hence my question again, what has changed since then?

      Firstly, there is nothing wrong with something being an "inference." If I let go of a paperclip a thousand times and it drops to the ground every time, I will make the inference that if I do it again, it will drop again. That doesn’t mean it will drop, but there is no reasonable basis for claiming that it won’t – unless you have access to further information (say, someone installed a powerful magnet in the ceiling since the last time you tried).

      All predictions about how the world works are inferences. It is an inference that the next time you get in a car, you will arrive safely at your destination. This does not always hold, but it usually does, and so you make the inference that it will.

      With regards to your question – there is not enough space here to give you a complete description of the evidence for macroevolutionary change (such as fins to legs). If you would like to understand that evidence, a complete treatment may be found at http://www.talkorigins.org/faqs/comdesc/, or a shorter one at http://en.wikipedia.org/wiki/Evidence_for_evolution.

    • #110317
      AstraSequi
      Participant
      quote scottie:

      quote :

      It depends what you mean by “unlikely.” While any individual mutation is unlikely, that doesn’t mean that it will not happen on a regular basis if you give it enough chances.

      So the question therefore must be, how many chances does “enough” mean?

      It depends on exactly how confident you want to be that you will get the desired result. For example, I might specify it to be the number of chances for which you will get that result on average about ten times. In this case, if the result had a one in a million chance, I would want ten million chances. Of course, I would probably get that result far sooner than the ten millionth chance.

      Of course, for any particular mutation, it is possible to calculate the exact probability. (I realize that you have now started talking about multiple mutations as well ‒ I will address that below.)

      Sample calculation:
      There are several single point mutations in DNA gyrase which is sufficient to confer resistance to quinolone antibiotics. (Which, I will point out for your discussion with Luxorien, is clearly a beneficial mutation when you are being treated with these antibiotics.)

      Let’s consider just one of these mutations, S83L in the gyrase A subunit, which is a C→T transition. (The first observation of this mutation was here: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC245014/.)

      E. coli has a mutation (without repair) about 1 in 300 replications.

      Its genome size is about 4.6 Mb (4.6 million bases), so you have a 1 / 4,600,000 chance of the mutation hitting the base in question.

      Since there are three possible bases it could change to, there is then a 1/3 chance of the mutation changing it to a T, rather than an A or a G.

      A quick multiplication shows that the probability of this mutation happening is about 1 / 4,140,000,000. Each time an E. coli bacterium divides, there is a 1 / 4,140,000,000 chance of this mutation happening.

      In other words, if I take 4.14 billion E. coli, about one of them will probably have the mutation. (In fact, approximately every possible E. coli mutation would be present around once.)

      4.14 billion is fewer E. coli than you would find in a half-full test tube.

      If I took that many E. coli and let them divide three times (multiplying the population by 8), you would produce the mutation de novo about 7 times. This would take about an hour.

      The point is that generating any particular mutation is easy.

      quote :

      quote :

      Suppose there is a mutation that has a one in a million chance of happening – you can call this unlikely. However, if a million fruit flies are born, then it will probably happen around once. If you then wait for a thousand generations, it will probably happen around a thousand times.

      You are missing your own point here. The problem is that the second mutation has by necessity, have to build on the first for some fitness function to begin to arise. This is where your probability analysis falters. Your analogy refers to the same mutation arising. (the point you are making for your analogy)

      So you understand that I wasn’t talking about mutations over time, but rather the likelihood of a single mutation, right? (Further answer in the next point.)

      Also, I don’t know what you mean by a “fitness function.”

      quote :

      In order for an improved fitness/function to arise, the mutation must be different but also it has to add to the function of the previous mutation.

      The probability for every mutation, by nature of its randomness, has to start from scratch every time.
      So by your analogy of a thousand generations, the progressive mutation towards fitness/function will not occur around a thousand times. It will be orders of magnitude more.

      Your statement implies that you are trying to use combinatorial probabilities where they are not applicable. You would only multiply if you were talking about multiple mutations that happened simultaneously.

      The idea of progressive change is that the mutations do not have to happen simultaneously. Let us take the same example – mutations with a one in a million chance, which will still happen very frequently over a thousand generations of fruit flies. That is, they will happen individually around a thousand times each.

      Even if one mutation is only adaptive if the first one has already been made (that is, the second one builds on the first, the probability is not low. The genetic context has changed by the time the second mutation happens. As soon as the first mutation happens and takes over the population, the second mutation cannot do anything but build on the first one.

      The applicable probability calculation would be the chance that the first mutation happens at least once, followed by the second mutation happening at least once. (To be more realistic, you can also stipulate a several-generation time lag as the first mutation takes over.)

      In fact, in this example (a thousand generations with each mutation happening about once per generation ‒ 40 years for a fruit fly), it would happen almost immediately. The first mutation would almost certainly occur at least once in the first couple of generations, you can give in a few more generations to become fixed, and then the second mutation will happen approximately once in every generation after that. In fact, you could get hundreds of sequentially adaptive mutations (if such a series actually existed) by the end of the thousand generations.

      I will also point out that multiple mutations that happen simultaneously, even with the orders-of-magnitude-lower probabilities, are still very much within reach. This is especially the case in bacteria. However, the point is that it is not necessary to do this in order to build function on top of function.

      quote :

      Also please remember that mutations are invariably deleterious to the organism. Take for example the mutation that causes Cystic fibrosis. As I understand it, this is a mutation caused by the deletion of three nucleotides. This is a fairly common mutation and deleterious, it is in the nature of most random mutations.

      You know that “invariably” means “always,” right? If that is the case, the third sentence of this quote (where you use the word “most”) is in contradiction with the first.

      quote :

      For NS to select for survival or “fitness” whatever that should mean, the mutation needs to be a positive one. Now since most of these mutations are deleterious, any positive one, has to not only evolve for greater fitness or function, but it also has to offset the downward pull of the many harmful mutations that are also taking place.

      This is where you do use conjunctive probabilities – the harmful mutation has to happen in the same organism as the beneficial mutation. As a result, this occurrence is much rarer. If strongly harmful mutations were so common as to appear with high probability in every organism, then everything would be dying quickly whether they had beneficial mutations or not.

      If they do happen to appear in the same organism, then yes, you have a conflict. Then, if the effect of the harmful mutation is greater, the double mutant will be selected out and the beneficial one will have to arise in the population again. If the effect of the beneficial mutant is greater, the double mutant would survive and take over the population, and eventually the harmful one would be reverted by another mutation. (Or, if the beneficial mutation is frequent enough, the double mutant would survive but would be outcompeted by an animal that had gotten only the beneficial mutant in the first place.)

      Two other points:
      – Actually, the majority of mutations are neutral – the majority of the rest are deleterious.
      – To answer your comment in the first sentence: “fitness” always refers to the number of viable offspring left behind. However, it is often used to describe anything that correlates with the number of viable offspring left behind (for example, skill at avoiding predators) as well.

    • #110318
      AstraSequi
      Participant
      quote :

      Another thing to please keep in mind, these examples of random mutations provide evidence of what is termed micro evolution and in a negative way at that, the deterioration of the organism. Nobody as far as I am aware denies that these changes take place. The point is do these changes lead to new species formation.

      (See the links I gave you above.)

      quote :

      And this of course leads to another related question. What evidence do we have of the positive effects of any random microevolutionary mutations?

      You just said,

      quote :

      Nobody as far as I am aware denies that these changes take place.

      If you are asking this question, it implies that you’re denying this anyways. 🙂

      And again, examples have been given ‒ such as the DNA gyrase example I gave above, as well as in your discussion with Luxorien.

      quote :

      The body plan must be altered in some way for speciation to happen.

      Definitely not. For example: changes in chromosome number, changes in behaviour (for example, mating rituals), enzymatic changes in the reproductive system, etc.

      quote :

      I would ask, what evidence that the segmented nature of the body plan of the fruit fly has changed throughout it’s existence, regardless of how rapid its generation time may be.

      Segmentation is perhaps the most successful body plan in existence. The three-segment body plan of the insects has not significantly changed since their common ancestor. It is entirely unsurprising under natural selection that some things do remain unchanged.

      (And of course, the word successful refers to fitness)

      quote :

      Recall Richard Lenski’s 22 year experiment with bacteria (I have covered this before). After over 50,000 generations in each of 12 populations (600,000 generations) no new species of bacteria arrived.

      If you have covered this before, perhaps you have been informed that the term “species” does not apply in the same way to bacteria as to sexually reproducing organisms.

      The appearance of the Cit+ strain (a change in one of the fundamental identifying criteria) is essentially as close as you can get to speciation for a bacterium. Lenski has made this point as well.

      quote :

      I don’t know much about the Bonferroni correction…

      Then look it up – this is how you learn. 🙂

      quote :

      quote :

      The probability of something happening increases as the number of times it is possible to occur increases.

      This is with regard to the same thing happening again and again. But for a new mutation to provide a positive outcome it must add to a previously positive one and in a positive way, to succeed. In other words (as I have previously stated) it must be a different type of mutation.

      I have addressed this above – you want to use probabilities of successive occurrence rather than conjunctive occurrence.

      quote :

      Take the cystic fibrosis mutation (the 3 nucleotide deletion), it can repeat itself over many generations in a population, but it is the same mutation. It doesn’t add anything.

      Correct, because it is negative – it does not spread within the population. If it did, then everyone would have it, and every new mutation would have the potential to build on it.

      quote :

      Also in addition to this one that I have cited, I am informed that there are some 200 other mutations of this gene that have been documented. So mutation of this gene is fairly common. Only a few lead to the severe form of this disease while others cause lesser problems, but, there are no beneficial results.

      Since people generally only get the CFTR gene tested if they are already suspected of having CF, it is unsurprising that only negative mutations are found.

      I am not saying that there are positive mutations that occur in the CFTR, but only that doing tests specifically on sick people is unlikely to find any.

      But by the way, did you know that CF mutations have been suggested to be protective against cholera? This is a similar idea as the sickle-cell mutation.

      quote :

      Systems biologists are increasingly recognising the robustness of cellular processes. Mutations (of all kinds) produce little phenotypic variation. If the mutation is serious enough the organism either becomes diseased or it dies.

      This is just a restatement of the claim that all mutations are negative.

      quote :

      Your roll of dice analogy simply does not apply.

      That is correct. The only point made by the analogy is that given enough chances, even the most improbable things happen – where “enough” depends on exactly how improbable the event is. If you want to look at changes over time that build on each other, you have to use a more complex analysis, as I detailed above.

      quote :

      Finally on what is the “scientific” view of mutations? Are they all random or are they also non random.

      Science is a method for learning about the world. Definitions cannot be “scientific” or “nonscientific” except insofar as they were based on scientific information, so I’m not completely sure what you mean. (See the next point)

      quote :

      Mutations originate both randomly, and also as a result of cellular processes, non randomly.

      This is about the process by which mutations are generated, and as such is not an answer to the question (which doesn’t really make sense, as I pointed out). It is also a restatement of something which I have already discussed.

      If you want me to restate my earlier responses, it would be something like this: changes in DNA occur in a probabilistic way, and evidence suggests that some changes are more likely under different conditions. It is not generally possible to predict the exact mutation that will occur, nor the exact time of its occurrence. These changes in DNA are the genetic variation which can be acted on by natural selection to allow change to occur.

    • #110319
      AstraSequi
      Participant
      quote :

      quote :

      quote :

      Has this situation changed since Darwin’s day? Can someone help with some evidence.

      Most definitely. I suggest you read http://en.wikipedia.org/wiki/Speciation, and also any included citations if you want to investigate further. Please note in the opening paragraph, “Observed examples of each kind of speciation are provided throughout.”

      Thank you for the wiki reference, and I have studied it.
      It does provide good descriptions of the different kinds of speciation evolutionary theory posits.

      The page is not about “positing”, but observation. 🙂

      quote :

      It goes on to exemplify this:-

      quote :

      One example of natural speciation is the diversity of the three-spined stickleback, a marine fish that, after the last ice age, has undergone speciation into new freshwater colonies in isolated lakes and streams.

      It provides a single reference in support of this, a 2000 paper.

      I think you could select more than one example – one which does not have some measure of debate surrounding it, as this one seems to. You could find even more examples at http://www.talkorigins.org/faqs/faq-speciation.html, for example (which I probably should have linked last time). Or perhaps you might consider ring species. 🙂

      quote :

      The first point I noted in the wiki discussion was, this example appears to be about variation within a species. Nobody as far as I am aware disputes that variation within a species does occur.

      So although they claim species divergence, they are still referred to three-spined sticklebacks (Gasterosteus aculeatus). I find that somewhat interesting.

      And what do you infer from the knowledge that this is “somewhat interesting”?

      It seems that they are different species, but nobody has yet gone through all of them (a difficult undertaking) to systematically record their similarities and differences and propose a new classification system. Or perhaps whether they are different species is not yet determined beyond doubt, and nobody will propose a new classification system until it is clear that one is necessary.

      After reading more on this particular example, it seems that there are many different populations, some of which can interbreed with each other and some of which cannot (similar to ring species), and that it is therefore difficult to assign species identifiers to any group until it is decided on how to handle situations like this.

      quote :

      In a more recent study found in the Journal of Fish biology we have this paper

      The introduction states that speciation is a continuum of 4 different stages, with the final one being the complete reproductive isolation, and this reproductive isolation is always associated with chromosomal rearrangements and environment independent genetic incompatibilities.

      Yes, in sticklebacks, and they make this suggestion based on two previous examples. They say nothing about other organisms. You can also search for “rearrangements” within the document and note that the claim for requiring genetic incompatibilities tends to be placed with qualifying words like “may” and “seem.”

      quote :

      The paper then goes on to examine these 4 stages in connection with the stickleback.
      1) continuous variation without reproductive isolation
      2) discontinuous variation with minor reproductive isolation
      3) strong, but reversible, reproductive isolation
      4) strong and irreversible reproductive isolation

      Only stage 4 can be classified as a speciation event and the paper points to only one example

      Isn’t “only one example” sufficient to refute your claim that no speciation can occur? And as I have already shown you, there are sources which supply many more such examples.

      quote :

      Why have these sympatric pairs not proceeded to the point of irreversible reproductive isolation? One possibility is the limited time frame for their divergence, given that most freshwater populations were colonized from marine ancestors only after the last glaciations…This explanation is not entirely sufficient, however, given that genetic incompatibilities have not been documented across the range of G. aculeatus, including among populations separated for millions of years…

      Another possibility, then, is that the divergent selection is not strong enough to generate irreversible barriers through ecological speciation. Equivalently, assortative mating may not be strong enough, perhaps because trait divergence is not sufficient for females to reliably or profitably discriminate against heterospecifics. Finally, irreversible isolation in sticklebacks may require specific genetic changes, such as chromosomal rearrangements.

      It may be relevant to point out that they do not say no selection is strong enough to generate irreversible barriers.

      quote :

      Finally, achieving state 4 (strong and irreversible reproductive isolation) seems to require additional factors, such as chromosomal rearrangements, intrinsic genetic incompatibilities and extended periods of allopatry, all of which are less obviously linked to processes occurring along the rest of the speciation continuum.
      Perhaps the greatest lesson that sticklebacks can reach is the value of plurality in the study of speciation. That is, speciation might often involve multiple and shifting geographic contexts and mechanistic drivers. This mosaic nature of speciation has also been suggested to characterize other taxa…and it might even be reasonably common in nature. The solution to Darwin’s ‘mystery of mysteries’ might therefore be considerably more complicated that proponents of parsimony might desire. Nature is not parsimonious.

      Again, even if these “additional factors” are necessary, that does not mean that these factors can never be supplied.

      quote :

      The apparent necessity of Chromosomal rearrangements within the nucleus pose a significant problem, if speciation is the product of random mutations to the genome.

      So your entire argument is that large-scale genetic changes are required for speciation, and that such changes are not possible?

      First, the authors only suggest that there is such a necessity in sticklebacks, and you have taken it as fact for all species.

      Secondly, you haven’t made any argument for why such changes actually aren’t possible.

      quote :

      We know the nucleus of each differentiated cell appears to possess an epigenetic mechanism.

      Do you mean, “we know that the nucleus of each differentiated cell appears to be regulated epigenetically”? If so, then I agree (and the evidence for this is far stronger than “appears to be” – I would just use “is”).

      There are lots of epigenetic mechanisms, not just “an” epigenetic mechanism ‒ histone acetylation, histone methylation, cytosine methylation, etc. Undifferentiated cells also have epigenetic mechanisms.

      quote :

      This mechanism regulates the position of each chromosome in the nucleus and thereby determines the way and timing of how expression takes place. We also know chromatin structure, the variation in histone 3D structure and so on are indeed regulated by this mechanism.

      Agreed.

      quote :

      So the control of chromosome activity in the nucleus clearly cannot be the product of a mutation in the genome.

      We are observing levels of information and control above and beyond genome information.

      The proteins involved in epigenetic control (such as histones) are themselves encoded by the genome. They don’t appear out of nowhere.

      Yes, there are some proteins which affect the expression of other proteins. This means that a mutation in a regulatory protein will also affect the expression of the proteins it controls.

      quote :

      All of these are not instigated or varied or regulated by mutations to the genome…

      See the previous point.

      quote :

      …and yet this study (which is very detailed and is really worth studying in full) is concluding that chromosome rearrangement is a requirement for speciation, whereas neo darwinian evolutionary theory is fixated on random mutations of the genome.

      Chromosome rearrangement is a mutation. Check the definitions that you gave earlier ‒ this is one of the ones you said you agreed with.

      quote :

      The term mutation can refer to any process that changes the genetic information in the genome, including DNA insertions, deletions and rearrangements.

      And as already discussed ‒ rearrangements are random as well. Or to avoid giving the wrong impression, they are probabilistic.

      quote :

      Ones like Donald Forsdyke have long recognised this link between chromosomal arrangement and species specific traits, only to be castigated by the likes of Coyne and Orr with their gene centred views.

      I think you need specific examples if you want to make such a general claim.

      quote :

      So I conclude that despite the wiki appraisal of speciation as being a darwinian process, the evidence suggests no such thing.

      The discussion above only refers to the fact that speciation has been observed, not the mechanism ‒ observation and mechanism are, of course, two different things, which involve separate bodies of evidence.

      Of course, since there are only two forces which are known to cause changes in species ‒ natural selection and genetic drift ‒ it is reasonable to conclude that one of these is the cause of speciation. The roles of each of these took some time to determine, but the evidence eventually showed that natural selection was probably the dominant factor.

      I will also point out again that you are attempting to use one example only (and a complicated one as well), and trying to generalize to every species in existence. This is not a very strong line of reasoning. 🙂

    • #110320
      AstraSequi
      Participant
      quote :

      The question of “correct” mutations being random makes no sense when we are dealing with for example proof reading. This type of process requires some template to compare with in order to be “correct”.

      No, I am not implying that there is some specification of “correctness” in evolution. I used the term “correct” as a shorthand to mean, “the mutation we are talking about, which will confer some selective advantage” – as opposed to any of the neutral or deleterious mutations that might occur instead.

      quote :

      How about checkpoint systems during cell division. Here again there must be some template by which the process is able to determine when the process is ready to move on to the next stage.

      The checkpoint systems are the template. When certain criteria are fulfilled, the checkpoint proteins allow the system to move on to the next stage. If the criteria are not fulfilled, the checkpoint proteins prevent this.

      And of course, mutations to the checkpoint systems will change the template, and the new template is then subject to natural selection. However, since this system is critical to cellular survival and many other systems depend upon it, it is already highly optimized and will not change very fast.

      quote :

      In other words there must be some body plan by which these mutations can be compared in order to make any determinations as to whether to continue or abort.

      I don’t know what the reference to the “body plan” means. If you meant to say “template,” I have answered that in the previous point.

      quote :

      No one as far as I am aware has even adequately addressed the how cell differentiation can be the result of random mutations to the genome.

      You made the same claim later, about the appearance of the genetic code. I will answer it there.

      quote :

      quote :

      For example, if we put some bacteria in nutrient-rich media, they will always start to grow faster after some time. This experiment only takes about a week to run, and the change will always be in the same direction.

      That is to say, we observe that natural selection produces the same result. This will happen for almost any bacteria we can grow – the new environment favors those bacteria that grow the fastest, so long as we allow enough time to pass.

      The question is not whether the bacteria grow any faster, the question is does this produce any new species.

      …That’s not what I was discussing.

      The points I was making were that 1) the bacteria observably adapt to their environment and 2) the adaption is reproducible no matter how many times you run the experiment.

      I was responding to your apparent view that if mutations are random, the same adaptation cannot arise independently more than once. Quote (page 39, post 1):

      quote :

      This is evidently a programmed response to climate (temperature) change… Please note that three separate populations on three different continents developed these same inversions and in an “evolutionary” short space of time.
      How this can be the result of random mutations, which according to darwinian theory they would have to be, unless of course one is happy to play with unlikely statistics.

      Of course, that does not mean that the adaptations are exactly the same ‒ the response is not programmed, as I discussed earlier. The mutations will occur at different times, and will often be slightly different. It is the phenotype which is the same, which is the important part.

      quote :

      The Lenski experiment has clearly shown that no new species has emerged despite all the mutations that occurred.

      Replied above.

      quote :

      For a start there has not been enough time in earth’s history for any probability theory to be used in connection with these ideas.

      What is “not enough”? How much time would be enough? Also, which specific “ideas” are you talking about?

      Even if you think that the world is less than 10,000 years old or something like that, there is plenty of time for at least some speciation to occur. I agree that you probably couldn’t make major evolutionary jumps, but you would still observe speciation happening.

      I also point out that you said above,

      quote :

      You are right variations can happen quite fast.

      Do you still agree with this statement, or do you have some meaning of “variations” that would not include the variation I am discussing in my probability example?

      quote :

      quote :

      quote :

      Natural Selection is not a force but simply the naturally selected result of random forces. The driving force in darwinian theory is the random mutations that allow nature to select from.

      I think this is semantics. Both stages, the mutations and the selection, are required for species to adapt. If there are no mutations, no variation is generated and no change can occur. If there is no selection, only random change can occur.

      This is not about semantics. Random Mutations are the driving force in Darwinian processes. The problem is that you have to rely on such vague terms as “enough chances” to try and justify the hypothesis.

      My point was that I think “driving force” is a vague term, and I’m not sure how establishing it is important to the discussion. Again, both the mutations and the selection are required.

      quote :

      quote :

      The enviromental stress in three different continents are not the same. What the researchers noted was that the climate/latitude was the common factor. That is why they made the link with global warming.

      That is why I said:
      In the most charitable interpretation I can think of, I suppose it is possible to make some assumptions and then say that their data is consistent with a completely deterministic model. However, you cannot say that it is evidence for such a model against natural selection, because natural selection can account for the same results quite well, and without the extra assumptions.

      Well you are right. You can suppose it’s possible to make any manner of assumptions if you wish to be charitable. It may not refute NS but it is certainly evidence against as I stated

      No, it is not evidence – that was the point. As a general principle, if two different theories make the same prediction, observation of the predicted result is not evidence for either theory.

      If Theory A predicts that the sky is blue, and Theory B predicts that the sky is blue, and then we go out and look at the sky and it’s blue, that tells us nothing about which theory is correct. I apologize if I am being overly blunt.

      quote :

      quote :

      If the capacity for change is limited as this researcher warns, then what happens to the theory? After all climate has always been on the change throughout life’s history.

      Natural selection does not say that the capacity for change is unlimited. It might perhaps be the case, but only given enough time – the rate of change over any particular time scale is limited by the amount of pre-existing variation in the population, and the rate of production of new variation (that is, the rate of mutation).

      I haven’t suggested that NS in unlimited, however it is attributed with going from Amoeba to Man. That’s a very bold claim, so what is the evidence to back it up. [/quote]
      …But that wasn’t what we were talking about. I was replying to the quoted statement, “If the capacity for change is limited.” It certainly looks like you were suggesting that natural selection only works if the capacity for change is unlimited.

      Of course I can reply to this new statement as well, and I refer you to the pages I linked when we were discussing macroevolution above.

      quote :

      quote :

      If the rate of change is too fast, the species is unable to adapt and goes extinct. Climate has never changed as fast as it is now in any point in Earth’s history (save perhaps the mass extinctions, and of course they didn’t go too well for life!)

      It’s not a question of whether the species goes extinct. Species do go extinct. The point is whether they change into new species. That is what Natural selection is supposed to accomplish.

      I was trying to illustrate the concept that adaptation is always a race – the organism must adapt faster than the environment can change, and this is the criterion for when species go extinct. (In this context, “environment” broadly refers to any change that might affect the species’ reproduction.) I thought that this might help you better understand the paper.

      quote :

      quote :

      quote :

      Well actually I cannot think of any reason why Dr Huey would be disturbed, other than this change does not sit well with evolutionary theory.

      Very well – it is related to what you said above. Drosophila is a highly successful species, with a very short generation time and the ability to adapt very quickly to new environments. When we see such a species changing very rapidly, it means that it needs to change that fast in order to stay adapted to the environment. (Or, in an even worse case, that its rate of change is at maximum, and it would be changing even faster if it could.)

      This means that any less successful species, which cannot adapt as fast as Drosophila is adapting now (and which does not have other options such as migration), is likely to be in great difficulty.

      In fact, I can tell you what the authors of the paper say, in their concluding paragraph:
      The increasing numbers of examples documenting genetic (2–5, 8, 10, 11), as well as phenotypic (1, 2) responses, to recent climate change are not surprising from an evolutionary perspective, but nonetheless are disturbing from ecological or economic ones, because such changes signal inevitable disruptions in the distributions, population dynamics, and community interactions of organisms (1, 2).

      (My emphasis.)

      I am aware of their “not surprising from an evolutionary perspective” view but are they speaking from the perspective of speciation? The fact is they are not. The variations they are referring to are variation within species that appear to be governed by cellular responses to climate change. If natural selection was at work (in other words if NS was causing these changes) why would they be disturbing?
      After all is it not expected that natural selection will result in changes such as these. They are disturbing because they don’t sit very well with Natural Selection expectations.

      To whom are they (supposedly) disturbing for this reason?

      Previously, you were saying that the authors found it disturbing for this reason. I then gave you a direct quote from the authors saying that they found it disturbing for a different reason.

      Also, did you understand my response? You didn’t comment on anything other than my last paragraph out of three.

      quote :

      quote :

      I definitely agree with you that the authors know more about this topic than us. However, you will then need to accept these statements as well. 🙂

      I accept their data not their “disturbing” perspective.

      That’s fine, but
      1) you previously asked me to accept something they had said because they had said it, which is the reason I made that comment. (Page 38, post 10).
      2) we were talking about what disturbed him. I think that a direct quote answering that specific question is sufficient to provide a definitive answer.

      (See below for my final post.)

    • #110322
      cyanodave
      Participant

      I havent cared to read all 44 pages of reply’s and I’m fairly certain you’ve enough material for your paper at this point though I feel certain things oughtn’t be left out of your paper. With evidence provided by the Miller-Urey experiments it is known the general composition of our early atmosphere was capable of producing something that we today might identify as lifelike- presumably a protobiont with a primitive lipid membrane and some means of reproduction- presumably RNA. under proper circumstances these RNA molecules could multiply, though it is doubtful any kind of orderly cellular structure developed for millions of years, a simple strip of RNA may as well be classified as a living thing due to it’s ability to reproduce.

    • #110323
      AstraSequi
      Participant
      quote :

      quote :

      Also, observing rigorous data contradicting evolution would not be disturbing to scientists in the same way – it would be interesting.

      So scientists are now relying on symantics are they?
      …How then did the program arise?

      I don’t understand what you mean.

      I was pointing out that scientists are generally interested when it is shown that some previously accepted belief is false (and the scientists that do this usually become the most famous as well) – because it means that our beliefs have been made more accurate.

      quote :

      The common ancestor argument is an assumption. The creationists argue that the data this argument rests on is equally applicable to the creation argument..

      I am glad to see that you understand the data is equally applicable to both arguments point which I referred to above.

      Also, I don’t know what you mean by “the common ancestor argument.” If you are referring to the statement “a universal common ancestor existed,” then it is an inference from the data. One line of evidence supporting this is that the fossil record shows less and less diversity as you look in older and older rocks.

      quote :

      So this is no different to the “God did it argument” except in your case you are only moving the problem back

      So in other words, you agree that a “God did it” argument (that is, a general statement with no evidence) is fallacious?

      So you understand that “proving evolution false” would not mean that creationism were true, since the two are separate things. It is possible for both to be true (as long as you don’t insist on interpreting your scripture literally) or for neither to be true – although I see no need to publically endorse a position on that here since it’s not relevant to this argument.

      quote :

      The method by which the common ancestor arrived is no different to how Drosophila arrived.

      Since this statement presupposes the existence of the common ancestor, I suppose that my inference about your “common ancestor argument” statement above is wrong? However, if so, I don’t know what you mean by “common ancestor argument.”

      I also agree with the statement, with “the method” being natural selection. The common ancestor was not the first form of life, only the one from which all current life is descended.

      quote :

      Ernst Mayr one of the fathers of the Modern Synthesis in his Crafood Lecture put it this way.
      http://www.biologie.uni-hamburg.de/b-on … luence.htm

      quote :

      A most important principle of the new biological philosophy, undiscovered for almost a century after the publication of On the Origin of Species, is the dual nature of biological processes. These activities are governed both by the universal laws of physics and chemistry and by a genetic program, itself the result of natural selection, which has molded the genotype for millions of generations.

      If you could describe why you quoted this (out of all the possible paragraphs in the speech), it would help me understand what point you are trying to get across. It doesn’t seem to be related to your following statements.

      quote :

      According to Mayr, God didn’t do it. Natural Selection is what did it via common ancestry. That was his philosophy as he himself has put it. But you eventually get back to the single cell. He provides no explanation any more than Darwin himself did.

      How did the cell emerge? There is no plausible answer that scientists can envisage other than by some outside agency.

      There are most certainly answers that scientists find plausible. For example, http://en.wikipedia.org/wiki/RNA_world and http://en.wikipedia.org/wiki/Iron-sulfur_world_theory

      These do not address the origin of the cell per se, but rather are theories about what came before the cell, which I’m sure you’ll agree is a prerequisite before the experiments to investigate how non-cellular life became cellular life.

      And if we don’t know, is there something wrong with that? Science does not claim to know everything. However, there is no special reason to think that once we know enough, a problem which currently is unsolved will not be solved in the future. It has certainly happened enough times in the past, after all.

      quote :

      My argument is simple. The same process that caused the cell to emerge is the one that has caused the different species to emerge and that is by an outside agency.

      This is not an argument, but rather an assertion. (Arguments have both premises and conclusions. 🙂 )

      If your argument is that we do not know how the cell emerged, therefore it was an outside agency, then that is argumentum ad ignorantium.

      quote :

      Craig Venter has shown that an outside agency (his team) have managed to demonstrate proof of concept. Albeit not in the creation of life but how an existing life form can be changed by design.

      This is affirming the consequent. “It is possible for an outside agency to manipulate life; life came into being; therefore an outside agency was the cause.”

      quote :

      However in his intellectual arrogance Ernst Mayr classically contradicted his own argument. His philosophy as he states it, is “governed both by the universal laws of physics and chemistry by a genetic program” (his words).

      I don’t see where the contradiction is. All I interpret from these quotes is a number of statements about natural selection ‒ and I also infer Mayr felt that natural selection (the unifying principle of biology) was an important consideration in the philosophy of biology, which I imagine is probably unremarkable among these philosophers.

      Also, I am sure you know that science does not hold the words of any individual scientist as more important than the next. Newton was wrong about many things, Darwin was wrong about many things, and no scientist has any trouble saying so. Authority (at least ideally) derives only from the experiments that you are capable of and the results you derive from them.

      I think this might be something you’re having trouble understanding. A quote from a famous scientist does not mean that they were right – in fact, it doesn’t even say anything about the current state of knowledge unless it was made in the last few years. Even scientific papers have some chance of being wrong or containing wrong statements. I’m not saying that Mayr was necessarily wrong about any particular statement, but you seem to be assuming that I (or “scientists”) must agree with him simply because he said it.

      (I can’t think of any other line of thought that makes these quotes relevant to the discussion.)

      quote :

      Every scientist knows that a program be it genetic or otherwise does two things.
      1) It uses natural forces which are governed by universal laws
      2) It injects decision nodes into the process to over ride that natural progress and directs (governs) towards a specified goal.

      I’m not sure about “every scientist” – are you including those which don’t even work with programs? 🙂

      Anyways ‒ is this meant to be a definition, or a description? If a definition, where does it come from? If a description, what is the definition and how do these characteristics derive from it?

      If it is meant to be a definition, why not simply “A sequence of instructions that perform a specified task”? (slightly modified from the Wikipedia definition of “Computer program.”)

      quote :

      He then goes on to state as if it were a fact that it was natural selection that created this program.

      I imagine that he was speaking to an audience of scientists, and thus felt no need to justify something that everyone in his audience already knew the evidence for.

      quote :

      What decision node has natural selection injected into a process governed by the universal laws that has resulted in this genetic program?

      I imagine that you could analyse the Tree of Life using decision theory, but the Tree of Life is not itself a decision tree.

      The term “decision node” implies a single point of decision. Species do not reach a certain point in time and then get “forced” to choose one or the other path – change happens gradually, every generation, including when speciation is not occurring.

      quote :

      Natural Selection has to work on what is already there, that is why is regarded as a selective process. It does not create anything let alone inject decision nodes into any process.

      Natural selection works with what is already there, plus what is generated by mutations.

      If you wanted to use an actual decision tree, it would involve every occurrence (action or random event) ever done by or to every single member of the species that was relevant to its reproduction or lack thereof. On this level, natural selection most certainly is acting at the decision nodes – at every node, there is a change in the likelihood that the organism will reproduce.

      quote :

      For example how is the genetic code(s) the result of natural selection. There is no answer yet according to Mayr and all those who follow his philosophy, natural selection has somehow done just that. It is a dogma nothing else.

      Not really. The inference is something like this: the Theory of Evolution has accounted for the vast majority of the evidence, no other explanation can do this to nearly the same degree, therefore it is reasonable to conclude that it probably can account for the rest of the data as well.

      It is the same kind of inference as “the sun has always risen in the past, therefore I think it highly likely that it will do so tomorrow as well.”

      You may dispute the premises, but if you do not (and Mayr himself probably did not), then the inference itself is quite reasonable.

      To be specific: no, I do not know how natural selection built the genetic code. For all I know, it didn’t ‒ for example, perhaps it was built by an external agent (say, aliens with advanced technology). However, I see no reason why natural selection couldn’t have been responsible, so without external evidence I see no reason why I should go against Occam’s Razor and postulate an additional factor in my model.

      quote :

      quote :

      Actually – what do you mean when you say “programmed”? A definition might help to clear up any misunderstanding.

      Yes I did use the term programmed. I am not alone am I?

      I already answered this before ‒ this is not an answer to the question.

      quote :

      quote :

      If the change is dramatic (as you are suggesting) then new species would be expected to arise.

      Speciation requires a) differential selection on different parts of the population, b) very low gene flow between those two parts of the population, and c) the low gene flow to be maintained until enough change has occurred to prevent any future interbreeding. (There are other types of speciation, but they are not as well understood.) The authors point out in the paper that criterion b is not met – in fact, that the gene flow is unusually high. As a result, criterion c cannot be met either.

      quote :

      quote :

      quote :

      Why would that be disturbing? Surely this is the natural way, according to the theory

      As mentioned above – the authors say it quite well. Of course, it is not as disturbing for the future of life on earth as a whole, which will probably carry on no matter what we do.

      Your assumption is that climate change is man made. You appreciate that the debate around this is quite vigorous.

      This is very much a non sequitur. I was talking about the results of climate change ‒ and pointing out why it would be disturbing, which is what you asked me to answer. Of course, man-made climate change is quite uncontroversial among scientists, but that is not the issue I was responding to.

      Also, you fused two of my replies to each other and only responded to the second.

      quote :

      Logic does not necessarily reflect reality as I have pointed out to you before. It can only be used if it is based on evidence, and with respect that is where your problem is

      So you are saying that logic only reflects reality if the premises of the argument are true? I agree with that.

      I also agree that if the premises of an argument are true (and the logical argument itself is correct), then the conclusions are also true.

      I also agree that for an inductive argument, if the premises of the argument are true (and the logical argument itself is correct), and the inductive argument has been shown to be correct many times in the past, then there is no reason to think that the conclusions are not true. This does not mean that the conclusions are true, but that it is unreasonable not to proceed under the assumption as if they are, until more evidence can be gathered.

      quote :

      …this is the price one has to pay for dealing with what is essentially a philosophical position trying to pose as science. 🙂

      But you agree that if something is supported by evidence, then it falls under science? Just to make sure that we share common ground on this.

      Thank you for the discussion.

    • #110333
      wbla3335
      Participant
      quote AstraSequi:

      Thank you for the discussion.

      Wow. You have far more tolerance of deniers than I do. They can resemble bricks sometimes, so I hope your efforts haven’t been wasted. Good job, though.

    • #110343
      einfopedia
      Participant

      there are 7 theories of a life.
      Panspermia

      Perhaps life did not begin on Earth at all, but was brought here from elsewhere in space, a notion known as panspermia. For instance, rocks regularly get blasted off Mars by cosmic impacts, and a number of Martian meteorites have been found on Earth that some researchers have controversially suggested brought microbes over here, potentially making us all Martians originally. Other scientists have even suggested that life might have hitchhiked on comets from other star systems. However, even if this concept were true, the question of how life began on Earth would then only change to how life began elsewhere in space.

      Simple Beginnings
      Instead of developing from complex molecules such as RNA, life might have begun with smaller molecules interacting with each other in cycles of reactions. These might have been contained in simple capsules akin to cell membranes, and over time more complex molecules that performed these reactions better than the smaller ones could have evolved, scenarios dubbed "metabolism-first" models, as opposed to the "gene-first" model of the "RNA world" hypothesis.

      RNA World

      Nowadays DNA needs proteins in order to form, and proteins require DNA to form, so how could these have formed without each other? The answer may be RNA, which can store information like DNA, serve as an enzyme like proteins, and help create both DNA and proteins. Later DNA and proteins succeeded this "RNA world," because they are more efficient. RNA still exists and performs several functions in organisms, including acting as an on-off switch for some genes. The question still remains how RNA got here in the first place. And while some scientists think the molecule could have spontaneously arisen on Earth, others say that was very unlikely to have happened.

      Other nucleic acids other than RNA have been suggested as well, such as the more esoteric PNA or TNA.

      Chilly Start
      Ice might have covered the oceans 3 billion years ago, as the sun was about a third less luminous than it is now. This layer of ice, possibly hundreds of feet thick, might have protected fragile organic compounds in the water below from ultraviolet light and destruction from cosmic impacts. The cold might have also helped these molecules to survive longer, allowing key reactions to happen.

      Deep-Sea Vents

      The deep-sea vent theory suggests that life may have begun at submarine hydrothermal vents, spewing key hydrogen-rich molecules. Their rocky nooks could then have concentrated these molecules together and provided mineral catalysts for critical reactions. Even now, these vents, rich in chemical and thermal energy, sustain vibrant ecosystems.

      Community Clay

      The first molecules of life might have met on clay, according to an idea elaborated by organic chemist Alexander Graham Cairns-Smith at the University of Glasgow in Scotland. These surfaces might not only have concentrated these organic compounds together, but also helped organize them into patterns much like our genes do now.

      The main role of DNA is to store information on how other molecules should be arranged. Genetic sequences in DNA are essentially instructions on how amino acids should be arranged in proteins. Cairns-Smith suggests that mineral crystals in clay could have arranged organic molecules into organized patterns. After a while, organic molecules took over this job and organized themselves.

      Electric Spark

      Electric sparks can generate amino acids and sugars from an atmosphere loaded with water, methane, ammonia and hydrogen, as was shown in the famous Miller-Urey experiment reported in 1953, suggesting that lightning might have helped create the key building blocks of life on Earth in its early days. Over millions of years, larger and more complex molecules could form. Although research since then has revealed the early atmosphere of Earth was actually hydrogen-poor, scientists have suggested that volcanic clouds in the early atmosphere might have held methane, ammonia and hydrogen and been filled with lightning as well.

    • #110351
      scottie
      Participant

      Sorry for being out of the loop for a while.
      My early childhood bout of chicken pox has revisited me in the form of shingles and has left me low for about ten days. Still not over it but have got back online to have a look at progress, if one could refer to any of wbla3335 posts as scientifically progressive 🙂
      AstraSequi
      Thank you for the time you have put into your final response. I will read through it all, that amount of effort is certainly worth due consideration.

      Luxorien
      Thank you also for your response. I will read and digest. I did prepare a little information to post on antibacterial resistance before I went down, so I will put it up later for you to comment on if you wish.

    • #110421
      Nick7
      Participant
      quote AstraSequi:

      …this reply took ~12 hours to make.. As a result, I’ll make this my last response.

      Looks like I missed the train by … a month or so, so it’s perfectly fine if you don’t reply to this one (there is nothing serious enough to reply to anyway). Time-wise your reply to Scottie was a heroic effort by the way (polar bear example was a bit excessive though …).

      quote AstraSequi:

      quote Nick7:

      Life is a sophisticated carbon-based nanotechnology and it heavily relies on preconditions. Where did the preconditions for the complex life come from? AstraSequi , on the previous page, used dice in the example ( “If you roll a pair of dice, your chance of a double 6 is quite low (1/36). However, if you try… a hundred times times, …it would be more surprising if you didn’t get it at least once.” ) What if I give you a pair of dice with no 6 present on them at all, how many tries do you need to roll a double 6? I’ve tried to make this point several times…

      …I’m quite sure I was talking about something completely different, specifically mutations. The analogy is meant to show that if there is a small chance of something, then you can be very certain of getting lucky if you try enough times. You can replace the analogy with two one-million-sided dice if you want, so long as you get a trillion chances.
      If you want to claim that there is literally zero chance for something to happen, you need a rigorous mathematical proof – nothing else is sufficient.

      I was not talking about mutations, obviously. I have simply recycled your example to make a different point to Wbla3335, which is …. Yes, there is absolutely zero chance for something to happen if the necessary preconditions are absent. And you don’t need any “rigorous mathematical proof”, just go to you kitchen and make an omelet without eggs…

      quote AstraSequi:

      quote Nick7:

      Why do you assume that preconditions just happened? For instance, what known cosmic law states that every universe popping into existence must have so many constants in physics?

      It is not an assumption – it’s just that there is no evidence in any direction

      If “there is no evidence in any direction”, then “any direction” is equally possible. If Wbla downgrades the design possibility from “equally possible” to “unlikely”, then he clearly makes a number of assumptions in his reasoning. One of the arguments I’ve heard so far was that the nature itself is "mechanistic and unguided" (therefore the entire universe, even though it’s compatible with the conscious life that observes it, must’ve come into existence through some "mechanistic and unguided" processes). That type of reasoning is called “self-reference”, and if you like “rigorous mathematics”, I can offer you some – consider Gödel’s incompleteness theorem. Simply put, it states that the system can not be objectively evaluated from within the system. And that’s what I pointed out using the computer simulation example – a conscious character created by a computer simulation will notice that it’s compatible with the laws governing its creation and existence, but will have no way of figuring out how the whole system came into existence (since he can’t step out of it and evaluate it from aside). Using Gödel’s theorem, I can also pull a thorn from canalon’s side, and answer the question “who designed the designer” in the most adequate, satisfying, intelligent and fulfilling manner. Here is the answer ….. I have no GODDAMN idea! If we can’t objectively evaluate our own system from within, how can we objectively evaluate outside systems from within our system? How designer came into existence? How / when and why ANYTHING came into existence? Why the whole space is not just an empty void? Who knows…

      quote AstraSequi:

      Also, if you wish to make a fine-tuning argument, you must remember to consider the anthropic principle. ….and also canalon’s previous post.) …

      That’s almost all I’ve been doing here so far – considering the anthropic principle. I’d love to step out of the anthropic principle, but then I’m going to have to argue about biology with an evolutionary biologist (and becoming a kamikaze has always been the last item on my “things-to-do-before-I-die” list). And it’s not that a biologist’s atheistic views are right or wrong. It’s just he is a pro, and I’m not. Let’s look at the canalon’s previous post.

      quote canalon:

      You are very right and very wrong at the same time. You are right that no law or anything else requires anything from any universe popping in existence. And that the fact that all the atoms are tuned so wonderfully (whatever that means) is essential to our existence. But you are very wrong in that it is not because of us that those things are so well tuned to allow life, but that life as we know it is there only because all those stuff happened to work together. If they had not been, you would not be there mistaking causes for consequences. For all we know there might be an infinite number of universes devoid of stupid creatures to wonder how nice was their non existent creator to tune everything to allow them to exist….

      1st, by “tuning of atoms” I mostly meant a “stellar nucleosynthesis”, for instance, related to the resulting abundance of Carbon and Oxygen (which triggered F. Hoyle’s famous phrase about “a superintellect” who “ has monkeyed with physics “ to allow life to appear http://en.wikipedia.org/wiki/Fred_Hoyle … osynthesis ).
      So, here is canalon’s suspicion….. I’m sitting here, observing the “tuning of atoms”, scratching my melon, and assuming that some holy spirit must’ve tweaked it for my sake. And, in reality, I’m failing to realize that I’m simply sitting inside one lucky universe, which I, obviously, by default happened to select from the population of not-so-lucky universes.
      And here is the truth… There is NO such a population of universes that we actually know of. The reality does seem to go beyond the observable realm (hence unexplained problems in physics), BUT we, actually, know NOTHING about any multiple universes. We don’t know what they are. We don’t know how and based on what laws they come into existence. We don’t know to what extent there is a causal interrelation between them. We don’t know if they even exist….

      Anthropic principle simply shows the effects – how all the bullets hit the bullseye (not gonna toss here any relevant links from physics and cosmology – everyone can google them), and says nothing about causes. The link you provided is not as much about anthropic reasoning, as it is about all kinda reasoning ABOUT anthropic reasoning, and it is heavily leaning towards discussion of the selection bias, that canalon suspects I’m guilty of. So, being a resident of only this universe, knowing nothing about what’s outside of it in space and time, and considering only anthropic principle (for the sake of this particular argument), I say that unguided and guided creation of our universe are equally possible. So am I guilty of the selection bias here?

    • #110422
      Nick7
      Participant
      quote AstraSequi:

      quote Nick7:

      Evolution doesn’t really seem to falsify creation, it falsifies the meaning you put into the word creation (the way you believe it should’ve happened if it were true).

      I don’t think this makes sense. The only thing that you can falsify is a hypothesis.

      I’ll allow you to refute your own statement. Here…

      quote AstraSequi:

      there is no way to falsify the hypothesis that our universe was created by highly advanced aliens…
      quote AstraSequi:

      …So you understand that “proving evolution false” would not mean that creationism were true, since the two are separate things. It is possible for both to be true (as long as you don’t insist on interpreting your scripture literally)…

      So, broadly speaking, can you really seriously create a scientific hypothesis, explaining how blind "the blind watchmaker" really is without a ton of assumptions and axioms?

      quote AstraSequi:

      quote Nick7:

      Scientific method works well with the evidence which supports purely mechanistic and consistently replicable natural phenomena.

      The scientific method works well with consistently replicable phenomena. As long as causality exists and remains consistent, the scientific method will work. .

      What if the causality exists, but it is not consistent? What if the causality exists, but it is not consistent AND it’s beyond observable reality?

      quote AstraSequi:

      quote Nick7:

      So….for example, would you accept a possibility of “supernatural” explanation for this http://www.sheldrake.org/Articles&Paper … e_abs.html ? Why not?

      The probability of bias or error in a single study is much higher than the probability that a “supernatural” force exists, times the probability that this force enables telepathy over long distances, times the probability that it is occuring in this circumstance, times the probability that nobody else would have found rigorous evidence for it even though it actually existed…This is where you get the phrase, "extraordinary claims require extraordinary evidence."

      That being said, a possibility? Sure – the only impossibilities are those that have mathematical proofs behind them. However, the probability is so low, given our current state of knowledge about how the universe works, that it is not reasonable to think that it might be true.?

      The probability higher than probability times the probability….. The use of the dice and probabilities is getting completely out of control… I’m getting a feel that we were discussing the game of Craps or something.
      Sheldrake didn’t take his research material from a thin air. The occurrence the he studied has been observed for generations. So it’s not exactly the case of “nobody else would have found” the evidence, it’s the evidence itself that triggered Sheldrake’s attention. If dogs don’t empress you, try homing pigeons. Every possible experiment to pinpoint what physical senses they use to get to a loft from great distances (up to 1800 km) has been done (frosted lenses for sight, anesthesia and isolated containers to deprive a pigeon from outward journey info, use of magnets and release in the spots with magnetic anomalies to affect a possible internal compass navigation, etc., etc, etc.). If you put ALL the results together, you will see a picture that looks either mixed or negative or inconclusive…. There is no “rigorous evidence” that would allow us to state without a shadow of a doubt what physical senses homing pigeons are exclusively relying on. Sure…. the more complex system you experiment with is, the harder it is to draw definitive conclusions, but, as far as I know, there is no even clear logical understanding of how returning to a loft could even be done under some of the experimental conditions that were created……
      What if there are missing elements in this picture? That’s why I used quantum entanglement as an example, when you see the effect, but you have NO idea what the cause of it is by definition.
      However, IF only quantum entanglement were not as mechanistic and replicable as it is, you would’ve rejected it too, because “given our current state of knowledge about how the universe works” the principle of locality in physics is supposed to work everywhere you look. Well, it doesn’t work with quantum entanglement, does it? Unfortunately for the dogs and pigeons, they are not Newton’s falling apples – their behavior is not exactly fully mechanistic. But, again, what if, just like with quantum entanglement, we can’t quite connect all the ends together for the same reasons – the invisible elements in the equation? "extraordinary claims require extraordinary evidence."? If you continuously failing to complete a jigsaw puzzle, and I’m suggesting that you might be missing some pieces… is that such an extraordinary claim? I’m not making a strong statement here, I’m defending an obvious possibility. And If you still demend the almighty “rigorous evidence”, I can only refer you to the extracts from the article I posted before again…
      http://www.newyorker.com/reporting/2010 … ntPage=all
      “…selective reporting is everywhere in science….We cannot escape the troubling conclusion that some—perhaps many—cherished generalities are at best exaggerated in their biological significance and at worst a collective illusion nurtured by strong a-priori beliefs often repeated.” ….. Such anomalies demonstrate the slipperiness of empiricism. …. We like to pretend that our experiments define the truth for us. But that’s often not the case. Just because an idea is true doesn’t mean it can be proved. And just because an idea can be proved doesn’t mean it’s true. When the experiments are done, we still have to choose what to believe."

    • #110423
      Nick7
      Participant

      Wbla3335 & canalon… I referred to you as "third people" throughout the post (sorry)… It’s not the sign of disrespect (I was just trying to squeeze everything in one post). Sorry again!

    • #110431
      AstraSequi
      Participant

      I’ll make a few comments, since this was a separate conversation. (I’m not replying to everything, though, and I probably won’t make another “large-scale” response here after this one. Unless I get tempted anyways. 🙂 )

      quote :

      Yes, there is absolutely zero chance for something to happen if the necessary preconditions are absent. And you don’t need any “rigorous mathematical proof”, just go to you kitchen and make an omelet without eggs…

      You most certainly do need a rigorous mathematical proof to show that it is impossible to make matter from something else.

      You said, “there is absolutely zero chance for something to happen if the necessary preconditions are absent” (my emphasis). This is a truism, because of the word necessary – which implies an absolute requirement. However, you cannot specify that the preconditions are necessary without mathematics.

      I assume you are including in your statement the claim it is impossible to create matter? This definitely does have to be mathematically proven – in fact, it’s been done, and shown to be possible: E = mc^2 (from energy) and virtual particles (from nothing).

      I recognize that your statement is actually allows for the use of “non-egg” matter as well, but I’m assuming you intended to make the stronger argument which I just replied to. (If you allow matter, there is no reason why you could not take other foods, break them down at the molecular level, and reassemble them into an omelet. It’s not possible with current technology, but it is possible in theory.)

      quote :

      …if you like “rigorous mathematics”, I can offer you some – consider Gödel’s incompleteness theorem. Simply put, it states that the system can not be objectively evaluated from within the system.

      I think the incompleteness theorem says quite a bit less than you would like it to. 🙂 It is a theorem about mathematical systems, and says that all consistent mathematical systems contain some statements which are true but unprovable within the system.

      I am not a mathematician or physicist, so I am willing to be corrected, but it seems that you are adding the premises that 1) the universe (or “reality”) is a mathematical system, 2) certain specific postulates are unprovable within this system (the theorem does not say that all postulates are unprovable), and 3) we do not have any way to leave the system or access anything outside of it.

      quote :

      I’d love to step out of the anthropic principle, but then I’m going to have to argue about biology with an evolutionary biologist (and becoming a kamikaze has always been the last item on my “things-to-do-before-I-die” list). And it’s not that a biologist’s atheistic views are right or wrong. It’s just he is a pro, and I’m not.

      I’m not sure what you’re trying to say. I think you’re making a faulty generalization though – not all biologists (or even close to all) are atheists.

      quote :

      So, being a resident of only this universe, knowing nothing about what’s outside of it in space and time, and considering only anthropic principle (for the sake of this particular argument), I say that unguided and guided creation of our universe are equally possible. So am I guilty of the selection bias here?

      The anthropic principle is about selection bias. I agree that it says nothing about the likelihood of a creator or creators – I was only trying to point out that a fine-tuning argument, which you seemed to be making, cannot distinguish between a creator and a many-worlds interpretation.

      Second: I’m not sure about claiming the two are equally possible. Just because there are two possibilities does not necessarily mean that the probability is 50%, since it should be possible to interpret information about any creator from the structure of our universe.

      You might find this link interesting, although I’m not really sure whether it’s related: http://lesswrong.com/lw/mm/the_fallacy_of_gray/.

      It also feels like you’ve also chosen an arbitrary way to divide up possible causes for the universe. If I change the statement to “Either the universe is a quantum fluctuation, or it was caused by a nonrandom but unintelligent event in some other universe, or it was created,” do these now all have a possibility of 33%? But then the likelihood of a designer would be lower than before. Since no new knowledge has been gained, this is a contradiction.

    • #110432
      AstraSequi
      Participant
      quote Nick7:

      quote AstraSequi:

      quote Nick7:

      Evolution doesn’t really seem to falsify creation, it falsifies the meaning you put into the word creation (the way you believe it should’ve happened if it were true).

      I don’t think this makes sense. The only thing that you can falsify is a hypothesis.

      I’ll allow you to refute your own statement. Here…

      quote AstraSequi:

      there is no way to falsify the hypothesis that our universe was created by highly advanced aliens…

      The two statements are consistent. I did not say that all hypotheses can be falsified (specifically, unfalsifiable hypotheses cannot be falsified 🙂 ). The point was that the word “falsify” only refers to hypotheses – you cannot falsify a “meaning.” In mathematical terms, the set of all falsifiable statements is a strict subset of the set of all hypotheses.

      (Of course, I was not saying that the “alien hypothesis” I proposed is unfalsifiable in principle, but that we cannot do it based on our current knowledge.)

      quote :

      quote AstraSequi:

      …So you understand that “proving evolution false” would not mean that creationism were true, since the two are separate things. It is possible for both to be true (as long as you don’t insist on interpreting your scripture literally) or for neither to be true – although I see no need to publically endorse a position on that here since it’s not relevant to this argument.

      So, broadly speaking, can you really seriously create a scientific hypothesis, explaining how blind “the blind watchmaker” really is without a ton of assumptions and axioms?

      I don’t understand. “The blind watchmaker” generally refers to evolution, so if we wanted to explain something more about evolution, we would update the theory itself rather than try and invent a new theory to explain it.

      quote :

      quote AstraSequi:

      quote Nick7:

      Scientific method works well with the evidence which supports purely mechanistic and consistently replicable natural phenomena.

      The scientific method works well with consistently replicable phenomena. As long as causality exists and remains consistent, the scientific method will work.

      What if the causality exists, but it is not consistent? What if the causality exists, but it is not consistent AND it’s beyond observable reality?

      I assume that these are not rhetorical questions. 🙂

      For the first question – if causality exists but is not consistent (and is not probabilistic either), then the scientific method does not apply to that circumstance. However, we have not observed causality to be inconsistent in any way before, so we can infer that it is consistent in most if not all cases.

      For the second question – it would again not apply, but we wouldn’t even know about it anyways because you specified that we can’t observe it. I’m not sure where this question is intended to lead, but I’ll point out that if you want to draw any conclusions based on it you would first have to determine that something really is unobservable.

      quote :

      quote AstraSequi:

      The probability of bias or error in a single study is much higher than the probability that a “supernatural” force exists, times the probability that this force enables telepathy over long distances, times the probability that it is occuring in this circumstance, times the probability that nobody else would have found rigorous evidence for it even though it actually existed…This is where you get the phrase, "extraordinary claims require extraordinary evidence."

      That being said, a possibility? Sure – the only impossibilities are those that have mathematical proofs behind them. However, the probability is so low, given our current state of knowledge about how the universe works, that it is not reasonable to think that it might be true.?

      The probability higher than probability times the probability….. The use of the dice and probabilities is getting completely out of control… I’m getting a feel that we were discussing the game of Craps or something.

      And that is sufficient reason to dismiss the argument? 🙂

      The point is that for the claim to be true, it would require several other highly improbable claims to also be true (and the probability of all of these claims being true is far lower than that – it is the product of all the probabilities). The claim has an incredibly low prior probability based on other evidence which is not directly related to the experiment but which is still relevant.

      quote :

      Sheldrake didn’t take his research material from a thin air. The occurrence the he studied has been observed for generations. So it’s not exactly the case of “nobody else would have found” the evidence, it’s the evidence itself that triggered Sheldrake’s attention.

      It has not been observed under conditions that screen out bias. For example, when you run actual blinded (and/or otherwise controlled) experiments testing psychic phenomena, you get far more negative results than positive. And of course, small numbers of positive results are unsurprising in statistics, with the exact proportion depending on what your p-values are.

      quote :

      If dogs don’t empress you, try homing pigeons. Every possible experiment to pinpoint what physical senses they use to get to a loft from great distances (up to 1800 km) has been done (frosted lenses for sight, anesthesia and isolated containers to deprive a pigeon from outward journey info, use of magnets and release in the spots with magnetic anomalies to affect a possible internal compass navigation, etc., etc, etc.). If you put ALL the results together, you will see a picture that looks either mixed or negative or inconclusive…. There is no “rigorous evidence” that would allow us to state without a shadow of a doubt what physical senses homing pigeons are exclusively relying on.

      I did not say that anybody necessarily knows the answer to everything, only that some explanations are more likely than others.

      quote :

      What if there are missing elements in this picture? That’s why I used quantum entanglement as an example, when you see the effect, but you have NO idea what the cause of it is by definition.

      …We don’t know what the cause is because we haven’t figured it out yet. There is no definition of quantum entanglement that involves not understanding the cause as an intrinsic part of the phenomenon.

      quote :

      However, IF only quantum entanglement were not as mechanistic and replicable as it is, you would’ve rejected it too, because “given our current state of knowledge about how the universe works” the principle of locality in physics is supposed to work everywhere you look.

      No, it is not “supposed to work everywhere” based on our current knowledge. Our current knowledge, since the discovery of quantum entanglement, is that the principle of locality may work everywhere, and it may not.

      Secondly: science does not care about the term “mechanistic” (which is a philosophical term and not a scientific one), but only “replicable.”

      quote :

      But, again, what if, just like with quantum entanglement, we can’t quite connect all the ends together for the same reasons – the invisible elements in the equation? “extraordinary claims require extraordinary evidence.”? If you continuously failing to complete a jigsaw puzzle, and I’m suggesting that you might be missing some pieces… is that such an extraordinary claim? I’m not making a strong statement here, I’m defending an obvious possibility.

      No, it is not an extraordinary claim. However, it is an extraordinary claim that particular pieces are missing (out of the huge number of pieces that could be), and that is what you seem to be doing.

      quote :

      “…selective reporting is everywhere in science….We cannot escape the troubling conclusion that some—perhaps many—cherished generalities are at best exaggerated in their biological significance and at worst a collective illusion nurtured by strong a-priori beliefs often repeated.” ….. Such anomalies demonstrate the slipperiness of empiricism. …. We like to pretend that our experiments define the truth for us. But that’s often not the case. Just because an idea is true doesn’t mean it can be proved. And just because an idea can be proved doesn’t mean it’s true. When the experiments are done, we still have to choose what to believe."

      And yet science is still better at predicting the world around us than any other method tried to date. 🙂

    • #110874
      JackBean
      Participant

    • #110892
      JorgeLobo
      Participant

      very sophomoric

    • #110896
      JackBean
      Participant

      I’m sorry?

    • #112022
      TheMatrixDNA
      Participant
      quote scottie:

      Continuing on with the problem ID has not addressed.

      As I stated in my last post.

      quote :

      They are shying away from the obvious implications of what design means.

      Design is always the product of a purpose the Designer has in mind

      Ok.In my opinion,this is the most instructive thread in the Internet for those that are interested in the question of "theories about origin of life". It seems to me that this thread is death, abandoned,and I can’t understand it because this question wouldn’t have an end till the day that scientifically someone prove how life has emerged. The normal behavior here, I think, should be everyone trying to reinforce his/her theory bringing on more evidences, while bringing on new evidences that deconstruct the other theories.
      Then, this thread must have no end because everyday the news are showing new facts that can be used as positive or negative evidence to the current theories.
      I had driven for a new theory of origins of life and even the universe, when I was living in Amazon jungle and observing the systems that composes that biosphere and inquiring how must be the state of the world, in its astronomic, atomic, and even the dimension of quantum fluctuations aspects, that has produced our kind of life. Of course, my goal now must be testing the whole theory against real facts. But I and the scientific enterprise has no the necessary tools for doing it just now. Then,what I can do with this theory? The same others are doing here: searching more thoughtful brains for doing a rational scrutiny of this theory, while showing the news about facts that are evidences in favor and showing evidences that I think, does not fit in another theories.

      Introducing the people to a new big theory, which requires a change of his/her world vision is a difficult task. Maybe only high intellectuals individuals with open minds that are retired and has time for spent here, like Scottie, could invest attention in your theory and debating it with you. The fundamental requirement is that you can communicate it in a language understandable and that your theory makes same sense in the light of modern known facts. For instance, we had a poster here, Leopol, with two problems: poor Google translations from Russian, a lack of evidences and a world vision that is not tasteful. But it is not justice and intellectually productive rejecting Leopol’s theory, we must deal with the details giving him the opportunity to advocate his world vision till he can not resisting anymore for lack of positive evidences. same thing I think must be the reactions about my theory, called "The Universal Matrix/DNA of natural Systems and Life’s Cycles".

      I am reading the whole thread, it is a lot of stuff, 45 pages. When finishing everything I will begin from the first post again, selecting those that are interesting to my theory and deserves a reply, proposing discussions. I know that this means that I will post here almost another 45 pages, because each post is interesting and touches the roots of Matrix/DNA world vision. I don’t know if the moderator will permit it, but I will try because this is the right thing to do. But, then there are posts that can not wait the application of this method, it is irresistible a reply just now, like this post from Scottie.

      I think there is a big difference about what "design" means when making comparison between the designs made by Scottie as an engineer and the designs that emerges in Nature. But we can see this difference only from the view point of another observer with another world vision. The way Scottie was educated for dealing with designs he can not understand that other things can do design without using a mind,a purpose. Let’s focus on the generation of a new baby’s giraffes. When mating, father and mother giraffes are doing same minded project of a design that will be real in the future? Or the future designed baby will be product of merely flow of natural laws? Could be possible that the flow of natural laws creates unpredictable complex designs? The phenomena of giraffes doing a new baby is not a proof that this is normal functioning in this world? Where is the mind behind this whole process? Where is the design while a female and a male genomes are fusing together inside an egg and during the whole process of gestation? I think that the design only appears outside the egg, ex-machine in relation to the egg. And the author of that design also are outside the egg, They are ex-machine in relation to the egg. They are natural construction by natural laws and they are not applying their minds for doing the design. Also the male and female giraffes has no purpose of doing the design that will emerges from their natural mating act.
      Someone here has any problem with my proposition? I will consider that no, and will continue.
      This biological phenomena of babies’ generation is the unique real fact known by everybody when a design appears in Nature. We know the causes, the authors, the process, the evolution of whole process.
      My question is: why every current theory (exception of Matrix/DNA Theory) forgets this phenomena when trying to understand what is going on in the whole Universe? Why every author of every theory made by human beings ( exception of Matrix/DNA Theory) believes that the explanation of universe’s and life’s existences is better when applying human imagination creating images of theoretical universes instead cleaning up the action of human imagination and applying what we see here and now, as real, over the whole universe for getting those explanations?

      If we try doing that, this universe will be merely a material structure in which, inside it, is occurring a process of reproduction, from something ex-machine. Every process of reproduction is a sum of small and gradual processes of evolution. The observer inside an egg will think that is watching evolution and really he is; but the observer outside the egg will know that the evolution is an illusion, a process inside something bigger, called "reproduction".

      The world inside an egg is a natural world, like the womb where the egg is located. If the universe is a natural world, why it should not be located inside a natural world, working, like the womb? Why people from TOE are imagining that babies giraffes are products of random processes filtered by natural selection exerted by the mother wombs’ giraffe? They are not… but their imagined universe is explained like that. Why people from ID are imagining that babies giraffes are products of previous design made by the mind of father and mother giraffes? They are not… but their imagined universe is explained like that. Why Matrix/DNA Theory is believing that babies giraffes are products from the normal chain of causes and effects through natural laws that are passing through the bodies of father and mother giraffes? It is and its universe is explained like that.

      What we see in this universe is the evolution of a unique system that appeared in shape of atoms, has evolved to shape of galaxies and to shapes of living beings. Like inside an egg a first cell has passed through several shapes. The final shape of the contents of a fertilized human egg has consciousnesses, but it appears as the last shape, maybe after the birth, ex-machine in relation to the egg. In the whole history of this egg never had the action of intelligence neither randomness. Why people are imagining a Universe that works in other way?! In the same way, I think, the process inside the egg and in relation to the egg is purposeless. There is no goal of the matter inside the egg, neither the action of an outside agency, as believed by Scottie, driven the processes towards a design. Do you believe that molecules called genes has the conscious goal of making a design in the shape of a giraffe? Do you believe that the parents giraffes or another entity outside the egg is acting inside the egg, driving its matter towards a final design, in shape of a giraffe? I can’t believe in that. But, if you apply everything in the same way over the whole universe, based in the current proved facts we have about the universe, you get everything working like the real world we are experimenting just now. Them why rationally someone could refuse this theory? Some ideas? But please, let’s work with facts, evidences only, Not ideologies or psychological analyses of the authors of these theories.

    • #112030
      TheMatrixDNA
      Participant

      The debate between TOE and ID also is about the question of a common descent.Is there something that is half-non-organic e half-organic? A kind of link between life and non-life? A link between the mechanical Newtonian state of matter in the world of 4 billion years ago and the biological organization of matter that appeared 500 millions years later? The very fact is that nobody could yet imagine how could be the structure and functioning of such half-organism/half astronomic system.Then, we still are divided between those like Stanley/Urey that believes in the natural transition from non-organic to complex molecules and those like ID, Scottie, NASA, saying that it was impossible the emergency of complex molecules.

      But… if we don’t have the scientific tools for solving this question, our Reason and intelligence has the ability of organizing the known facts into bigger boards elaborating theories, which can driven us to the right tools and applied scientific method.Remember the Oparin theory and Muller/Urey applying the theory in a experiment. One rational method is "comparative anatomy between the sun/atomic system and the first cell system". Listing the differences and similarities, calculating the action of transformations and evolution, we can get a theoretical design about how should be such link. I don’t know nobody else than me that has applied this method and the reason is understandable: a) The scientific thought at this time is driven by the reductionist method, not the systemic one, Then, people are reducing their focus over a small part of a system, like the primordial soup of Oparin, Urey, and all those applying positivist chemistry. Since that the first real living being was a complete eukariote cell, it was a complete and working system and not a part of system. It is rational to think that the creator of this cell must be a complete system.And since that the first living being here emerged from the matter of Earth ( or another astronomic body-panspermia), this matter must contains all informations of the creator system.If it was the primordial soup, the creator system must be there, in someway. So, before waiting the formation of complexes molecules with the vital force for continuing towards protein, RNA, Urey need reconstruct the reduced initial conditions to a non-organic working system, something where the forces responsible for this dynamic internal motion is the same vital force. In that soup and time we had only two known natural systems: atoms and astronomical. I tried during years to get a way for a systemic atom giving the jump towards complexes molecules by themselves and got no results. Then I tried the stellar system and no success either. But the design from comparative anatomy was pointing toward a direction: the galactic system.I will explain why.By the way, the scientific reductionist method never will find the transition between non-life and life because it is all about systems.b) When a problem is very difficult to solve, but the human being need a solution, imagination take the task, and the result is religions, etc.That is the causes nobody else could accept that the comparative anatomy between living systems and non-living could elaborate a better and rational theory.
      Ok, resuming this post, this method left us with a theoretical design of the half-living system that emerged from the primordial soup.It is not a atomic neither a unique planetary body, neither a stellar system. I spent seven years searching this system in nature and not found it. But…

      The properties that emerged with the first cell system must be: a) or the result of evolution ( normal flow of natural laws) from the properties of priors non-living systems; b) a product of design by an outside agency adapted to the properties of priors non-living systems; c) a third unknown alternative which must be searched by our Reason.

      And my theoretical design was the resume of these three alternatives together. The secret is that the "outside agency" is a natural thing, which has not designed the first cell system using intelligence, only transferring itself into the world, from which resulted the natural laws, which had the potential for to evolves towards the design of the first cell system. Everything like when a couple of giraffes makes a new baby giraffe. This was the third alternative. But, then, the link between non-living systems and the first living system was not the alone creator of first cell system, like giraffes are not the creators of animal kingdom. I was driven deeper into universal history till the Big Bang and there finding the depository of the force that gives the dynamic to both, non-living and living systems: natural light.

      So, how is the theoretical design of a link between non-living and living natural systems, which must explain all questions about these transition, first of all, the emergency of complexes molecules? How is the code that imprints the dynamism into matter transferred by light? How is this code imprinted in natural light?

      I have found that the solution suggested by Matrix/DNA Theory is very rational and logical. Now it is time for to expose the solution to the scrutiny of every another brain hard-wired in different way than mine, testing if the solution is rational in a global manner.And trying to get the participation of others for the fight of getting the scientific tools and doing the first experiments suggested by the theory. Someone there reading this post? I have got an apparatus defense against the first stones and eggs throwing towards me. Feel free.

    • #112034
      david23
      Participant

      can you write shorter posts

    • #112048
      JackBean
      Participant

      oh man, not again 🙄

    • #112109
      scottie
      Participant

      I apologise for my long abstention from this forum, but illness has taken it’s toll.
      However I am somewhat better now so may I perhaps continue to engage and no doubt irritate. 🙂

      Luxorien
      I did say I would put out some information on antibacterial resistance so here it is for any further discussion.

      Antibiotic resistance is often used to show that the development of this resistance in humans is a result of random evolutionary forces that natural selection uses.
      However what does the empirical evidence actually show?

      In the book “Bacteria versus Antibacterial Agents – an Integrated approach”
      http://books.google.co.uk/books?id=mayr … 8.&f=false
      Page 243 has this to say.

      quote :

      Resistance to tetracycline may be mediated by one of three different mechanism:
      (I) an energy-dependant efflux of tetracyclines carried out by by transmembrane spanning proteins which results in reduction of the concentration of tetracycline in the cytosol:
      (II) ribosomal protection, whereby tetracyclines no longer bind productively to the bacterial ribosome; or
      (III) chemical modification requiring oxygen and NADPH and catalysis by enzymes.

      Efflux and ribosomal protection, mediated by plasmid or chromosomal determinants, are the two major mechanism of bacterial resistance of clinical significance……

      Levy and co workers discovered that efflux is a major mechanism of tetracycline resistance in bacteria. They demonstrated that tetracycline-resistant cells lose accumulated drug faster than susceptible cells do and that tetracycline enters the bacterial cell by an energy-dependant process. The determinants which confer resistance by removing tetracycline from the cytosol encode transporter proteins located in the cytoplasmic membrane. These proteins mediate energy-dependant efflux of the tetracycline.

      As far as ribosomal protection is concerned the book goes on

      quote :

      The ribosomal protection proteins are all polypeptides …. These proteins interact with the ribosome, making it insensitive to tetracycline inhibition. |The exact mode of interaction of these proteins with the ribosomes is not well understood.

      There is the third mechanism not considered by the book

      Some bacteria produce enzymes that neutralize antibiotics groups to a specific site on the antibiotic. This modification reduces the ability of the antibiotic to bind to ribosomes, rendering it harmless to the cell.

      The interesting question here is, where do these antibacterial properties come from?

      Are they the result of blind random mutations that natural selection can select from.
      Here is what the data reveals.

      http://www.ncbi.nlm.nih.gov/pmc/article … ool=pubmed
      Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance.

      It notes

      quote :

      Tetracycline resistance is often due to the acquisition of new genes, which code for energy-dependent efflux of tetracyclines or for a protein that protects bacterial ribosomes from the action of tetracyclines.

      So the question naturally is, where do these genes comes from?
      It goes on

      quote :

      We have shown that the tet genes are found in the producing Streptomyces spp. and the otr genes are found in the nonproducing Mycobacterium spp. (Table ​(Table5).5). Eighteen of the tet genes and one of the otr genes code for efflux pumps, and seven of the tet genes and one of the otr genes otr(A) code for ribosomal protection proteins (Table ​(Table3).3). The presence of both tet and otr genes with similar efflux or ribosomal protection mechanisms of resistance is consistent with the hypothesis of lateral gene transfer from the tetracycline-producing streptomycetes to other bacteria (16)

       

      So Bacteria don’t appear to be evolving new genes at all, they are acquiring previously existing antibiotic resistance genes through lateral gene transfer.
      It goes on further..

      quote :

      Both efflux and ribosomal protection proteins are found in antibiotic-producing streptomycetes ……

      Thus, bacteria exposed to antibiotics in the environment or in animals can ultimately influence antibiotic resistance in bacteria of human origin

      So there is nothing new about antibacterial resistance, for it now appears to have been in nature all along.
      In fact Streptomyces uses these methods to protect itself from its own antibiotics. 🙂

      The idea that antibiotic resistance is so readily used to show that the development of this resistance in humans is a result of random evolutionary forces, actually runs counter to the empirical evidence.

      What the empirical evidence shows is that, it is the direct clinical intervention that induces the acquisition of these natural occurring mobile genetic elements in tetracyclines that produces the resistance.
      So this is not mutations selected by natural selection but (although unintended) artificial selection.
      In fact this paper makes an sound empirical observation.
      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC383146/

      quote :

      The low level of occurrence of tetracycline resistance among isolates from wild animals is presumably due to their low exposure to these antibiotics. Most of these isolates either had a high level of resistance or none at all, suggesting that the acquisition of a mobile genetic element accounts for resistance.

      Another point to keep in mind is this.

      Even if a mutation occurs in the ribosome that may provide an advantage to the bacterium, it would come at a cost. Ribosomal mutations, while providing antibiotic resistance for the organism, slow the process of protein synthesis, slow growth rates, and reduce the ability of the affected bacterium to compete in an environment that is devoid of a specific antibiotic.
      Furthermore, a mutation that confers resistance to one antibiotic may make the bacterium more susceptible to other antibiotics.
      These are deleterious effects and are completely inconsistent with the evolutionary model of natural selection acting on random mutations.

      What I find quite amusing is this statement you will find on wikipedia.
      http://en.wikipedia.org/wiki/Antibiotic_resistance

      quote :

      “Thus, a gene for antibiotic resistance that evolves via natural selection may be shared.”

      [/quote]
      Please notice that while this statement acknowledges that antibotic resistance results from pre existing genes that are transferred, it is followed by a simple doctrinal statement that these genes have evolved via natural selection.
      This is not science but simple philosophy, no different to a creationist statement like “God created the world in 6 days”

    • #112336
      scottie
      Participant

      Now that the Olympics and paralympics are over I am able to put away my armchair and pop corn and continue. 🙂

      One of the reasons I was amused at the wiki statement that a gene evolves via natural selection has to do with their understanding of what a gene is.
      Their definition is

      quote :

      A modern working definition of a gene is “a locatable region of genomic sequence, corresponding to a unit of inheritance, which is associated with regulatory regions, transcribed regions, and or other functional sequence regions “.

      This is not exactly correct and at least 5 years out of date, but let’s stick with it for the moment.

      Now lets see the description of Natural Selection according to this same wiki.

      quote :

      Natural selection is the gradual, non-random process by which biological traits become either more or less common in a population as a function of differential reproduction of their bearers.
      It is a key mechanism of evolution

      Remember of course, there has to be a functioning entity or biological trait for NS to act upon, and the only mechanism according to any branch of Darwinian evolutionary theory is some random occurrence that produces a function.

      Now the gene codes for amino acids that the cell needs to use. (we are not even going to discuss how this coding sequence could have come about.)
      Here is what wiki records about amino acids.

      quote :

      Amino acids serve as the building blocks of proteins, which are linear chains of amino acids. Amino acids can be linked together in varying sequences to form a vast variety of proteins. Twenty amino acids are naturally incorporated into polypeptides and are called proteinogenic or standard amino acids. These 20 are encoded by the universal genetic code. Nine standard amino acids are called "essential" for humans because they cannot be created from other compounds by the human body, and so must be taken in as food. (Again although not strictly correct we get the picture)

      http://en.wikipedia.org/wiki/Amino_acid

      In the simplest sense, expressing a gene means manufacturing its corresponding protein, which is a sequence of amino acids.
      So according to wiki, we have biological traits coded by genes that are randomly built without any purpose and are then naturally selected through some gradual non random process by which they get stabilised in a population.

      However, nearly 50% of these amino acids cannot be selected by the cell that the genes have coded for, because they aren’t there to select from. (the body doesn’t make them)

      So in order for this selective process to occur, there has to be a fully functioning digestive system so that when the food gets eaten, the nutrients travel down into the stomach and then intestines. These organs break up and dissolve the food into small pieces that can be absorbed by the blood stream. Most of these small particles travel from the intestines to the liver, which filters and converts the food into nourishment that the blood stream delivers to the cell. How these nutrients pass into the cell of course is another area we are not even going to go into for now.
      So the obvious question is :
      Which came first?
      The genes that code for the proteins using the amino acids that the body can make.
      OR
      The genes that codes for the entire digestive tract that provides the cell with the amino acids that body can’t make but which the body cannot do without.

      Isn’t it obvious that that the whole show has to be in place before any of these individual parts can functionally operate.
      But of course the obvious is not acceptable.
      Instead we have these doctrinal statements promulgated with a religious fervour, and any dissent from that view is considered heretical.

      The problem with all these just so stories is that they fall apart when the detail is examined.

      Wouldn’t it be nice to see some real science showing how Natural Selection produces a gene.
      But that’s hoping for too much, after all what has science got to do with a good story. 🙂
      This whole idea gets more farcical when we consider what the latest research on genes throws up.
      That however is better left for another time.

    • #112389
      Luxorien
      Participant

      Let me see if I’ve got this straight. Someone says to you, "beneficial mutations exist. Example: antibiotic resistance." And your response is, "this bacterium got antibiotic resistance from lateral gene transfer, therefore beneficial mutations do not exist."

      That’s like saying the grocery store couldn’t possibly be selling DVDs because Best Buy sells DVDs. In order to demonstrate that mutation is not responsible for antibiotic resistance, you would have to go through all cases of antibiotic resistance and show how lateral gene transfer is the cause in each and every one of them.

      A much better approach would be to look for papers which detail the spontaneous mutation of antibiotic resistance in the lab. If you fail to find such papers, that would be an indication that such mutations do not exist.

      It took me about thirty seconds to find such papers. I’m not sure how many you require, but logic says even one is enough to invalidate your argument. I’ve selected three to reference. The abstract for the first one can be found here:

      http://www.ncbi.nlm.nih.gov/pubmed/17184282

      Unfortunately, the full text is not available online (at least not that I could find) but the abstract gives a good idea of the content. This article reviews the current research on mutations which confer antibiotic resistance. It acknowledges that horizontal gene transfer is responsible for the spread of many mutations, but also references many instances where antibiotic resistance has arisen as the direct result of mutation.

      I was able to get a copy of the second source through my public library’s subscription to EBSCO. It’s an American Scientist article from 11/6/06 called "Free Upgrades, Unfortunately." The article describes a study where the researchers took samples of bacteria from people infected with M. tuberculosis. They did this at two different points in time: once early on in the infection and then again later, when the bacteria had had time to mutate inside the person’s body. They found mutations that conferred antibiotic resistance.

      "Okay," you might say, "but what if the patients picked up some resistant bacteria somehow? Those bacteria could have spread the resistance to them."

      Not only did antibiotic resistant bacteria show up out of nowhere in the patients, they also showed up in the lab. Researchers started with normal M. tuberculosis and exposed them to the antibiotic. They were easily able to produce several antibiotic-resistant strains.

      I intended to present this simply as an example of beneficial mutations, but it coincidentally contradicts your assertion that antibiotic resistance always comes at a price. The whole point of this study was not to demonstrate that mutations can cause antibiotic resistance (that’s well-established and they completed that task only incidentally as part of their methodology) but to see if antibiotic resistant strains evolved in vivo are as hardy as non-resistant ones. They found that, in many cases, they were.

      Now, I realize that citing papers which are not freely available online might seem like kind of a cop-out, so here’s one that is available in full-text:

      http://aac.asm.org/content/44/7/1771.short

      Again, the ability of mutation to cause resistance is taken for granted: the focus of the article is on the technicalities of measuring mutation rates. But there are still copious examples in this article of bacteria acquiring resistance through mutation. These mutations have been observed clinically as well as in the lab. Researchers can actually induce these mutations to order. They can cook up any resistance they want, using nothing more than their knowledge of mutation rates and the rapid reproduction of these organisms.

      I will mention something else about the costs of resistance. Though the American Scientist article indicates that there is not always a cost, I don’t mean to imply that there is never a cost. Of course there are costs. This is what I have been saying all along: the terms "advantageous" and "deleterious" are highly relative. They depend almost exclusively on context. A bacterium living in an antibiotic-free environment will probably not be as successful if it has a resistance mutation. But as soon as antibiotics enter the environment, suddenly it’s a stud, out-reproducing all its fellow bacteria. That is whole point of the combination of random mutations with directional selection: one fuels the variation on which the other acts. And steady mutation rates mean that even alleles which are eliminated from the population can pop up again later.

      You are somewhat correct to point out that, clinically, we can never be sure that a mutation has arisen because the conditions are not controlled. But many of these cases of resistance mutations occur in the lab. These are cultures that are carefully kept from contamination. No lateral gene transfer is possible in these situations.

      The only possible argument left to you is to contend that these variants are not arising spontaneously but were always there, hidden in the bacterial colonies in such small numbers that they were undetectable until exposure to antibiotics brought them roaring to life. If that is indeed your argument, then I have two challenges to offer:

      1) If mutation cannot cause antibiotic resistance, then why do mutagens increase the speed with which resistance-conferring variants arise?

      2) If these variants exist in such small numbers, and they get no benefit from their antibiotic resistance until an antibiotic is introduced to the environment, then how do they survive for so long and occur so frequently? Wouldn’t their relative disadvantage/small numbers increase the likelihood that they would, by chance, fail to reproduce and thus remove their alleles from the population? I mean, we might expect that some would survive by chance, but why is it that scientists can generate antibiotic resistance, under controlled conditions, in literally any population of bacteria they decide to test? How do you account for that without steady mutation rates?

      Edited to add a third question: how do these preexisting alleles for antibiotic resistance elude researchers who create pure strains from a single bacterium and even sequence the DNA of that bacterium to ensure that the allele is not present in its genome?

      To wrap up, your assertion that bacteria never get antibiotic resistance from mutation is astounding given the abundance of evidence to the contrary. You seem very concerned about the latest research, but the fact is that we’ve known about these beneficial mutations for decades. The latest research is way beyond that, investigating the details of how often these mutations occur, what other effects they have on the bacteria, how the mutations spread once they are introduced, etc.

    • #112390
      Luxorien
      Participant
      quote scottie:

      This is not exactly correct and at least 5 years out of date, but let’s stick with it for the moment.

      I’m not touching this trollbait with a ten-foot pole, lol.

      quote scottie:

      Wouldn’t it be nice to see some real science showing how Natural Selection produces a gene.

      I’m not interested in debating the origin of genes with you. As I said previously, I’m only concerned with the issue of beneficial mutations. However, you might be interested in watching (if you haven’t already) What Darwin Never Knew. It has some good visuals of the complexity of genomic interactions. The simple answer to your question is that genes are legos made of legos. Nothing is created de novo; it’s all built modularly. Do a Google search on "gene origins."

    • #112414
      scottie
      Participant

      Luxorien
      For the sake of clarity, and I have stated this before and will probably have to continue ad nauseam.

      My position is not that random mutations do not happen. They do.
      Does NS act upon random mutations. Yes I believe that may also happen.
      In other words, does evolution (change over time) happen. Yes

      However
      Does this mechanism account for species change, let alone the Origin of Species. (remember this is the subject of this thread)
      I argue NO
      Aside from a lot of adolescent rhetoric (not necessary from you)I see no evidence.
      Now
      I have also clearly stated about14351-480.html

      quote :

      There are random mutations that rearrange the DNA of the cell. These mutations are invariably the result of copying errors, breakdown in regulating functions like error correction, and DNA damage from environment like from chemical or UV radiation sources.

      There are also more mutations in DNA, by orders of magnitude, as a result of regulated cell processes, than those that are random in nature.
      The random mutations that do occur are invariably deleterious to the organism and are quite naturally the subject of intense study to solve or prevent health problems like cancers.

      I went on to state (not to you)

      quote :

      The point I make is this.
      The reality is that most genetic changes occur as a result of cellular processes in response to stress, damage and copying errors and are rectified in various ways, (I have not taken account of the developmental changes that occur) while most other mutations which for some reason not corrected, are deleterious to the organism.
      I haven’t even begun to talk about transposons and their part in genome restructuring. All these processes are under the control and regulation of the cell as it responds to stress and the maintaining of it’s own equilibrium.

      In the light of all this actual evidence (and with respect, not logic that you appear to rely upon) what does Natural Selection actually have to do?
      Where are the functional phenotypes that random mutation is supposed to have produced in order for NS to select from?
      It is no wonder that Darwin himself acknowledged he could recount no evidence for species change by NS.
      The reality is that NS has very eloquently described how species may survive but has nothing to say about how they arrived.

      Which is about where you came in.

      So let me turn to your question

      quote :

      Let me see if I’ve got this straight. Someone says to you, “beneficial mutations exist. Example: antibiotic resistance.” And your response is, “this bacterium got antibiotic resistance from lateral gene transfer, therefore beneficial mutations do not exist.”

      This is what I have stated.

      quote :

      What the empirical evidence shows is that, it is the direct clinical intervention that induces the acquisition of these natural occurring mobile genetic elements in tetracyclines that produces the resistance.
      I also went on to state
      Even if a mutation occurs in the ribosome that may provide an advantage to the bacterium, it would come at a cost. Ribosomal mutations, while providing antibiotic resistance for the organism, slow the process of protein synthesis, slow growth rates, and reduce the ability of the affected bacterium to compete in an environment that is devoid of a specific antibiotic.
      Furthermore, a mutation that confers resistance to one antibiotic may make the bacterium more susceptible to other antibiotics.
      These are deleterious effects and are completely inconsistent with the evolutionary model of natural selection acting on random mutations.

      It appears to me that you are raising straw man arguments here.

      The abstract you refer to is certainly not inconsistent with my statements.
      In fact if I may refer you to a more recent and complete paper in 2009.
      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684669/ entitled
      The role of natural environments in the evolution of resistance traits in pathogenic bacteria
      This is how the abstract begins

      quote :

      Antibiotics are among the most valuable compounds used for fighting human diseases. Unfortunately, pathogenic bacteria have evolved towards resistance. One important and frequently forgotten aspect of antibiotics and their resistance genes is that they evolved in non-clinical (natural) environments before the use of antibiotics by humans.

      All I have argued is that this resistance is already there in nature. The question is not how did the resistance in humans come about. We know that, well sort of!
      The question is how did these genes come about in the first place.

      That is what I found amusing about the wiki posit ie that NS is “what done it”.
      For that statement to be valid then empirical evidence is required.
      But what do we get.
      Well antibacterial resistance proves this. (Perhaps not you but others do claim this)
      With all due respect it does nothing of the kind.

      What it does show is that clinical intervention passes on a resistance that already exists in nature.
      That sounds to me very much like artificial selection. 🙂
      Not a very good one at that, since we are now having to deal with the consequences.

      The 5 years out of date comment has to do with the latest Encode definition of a gene. Nothing to do with trollbait.

      Ok so you are not interested in discussing the origin of genes with me but you do know the simple answer.
      Genes are legos made of legos.
      My my, however did I miss that one.
      Errr yep I’ve got it.
      I have been accused of lacking imagination, that’s what it must be. 🙂
      Got to keep working at it.!!

    • #112436
      Luxorien
      Participant
      quote scottie:

      My position is not that random mutations do not happen. They do. Does NS act upon random mutations. Yes I believe that may also happen. In other words, does evolution (change over time) happen. Yes.

      So, in other words…you agree that beneficial mutations exist. When you said "Where are the functional phenotypes that random mutation is supposed to have produced in order for NS to select from?" you did not mean to deny that an organism may acquire a beneficial trait from a random mutation. You simply meant that you didn’t think beneficial mutations sufficient to account for complex adaptations. By "functional phenotype" you mean the whole mouse trap, not just a piece of it.

      It sounds like what you’re saying is that natural selection can’t account for complex structures like eyes and blood clotting cascades because random mutation can’t produce eyes or blood clotting cascades.

      This is an argument I can understand. I don’t agree with it, but I can understand why someone would take this position. However, your statement that "The random mutations that do occur are invariably deleterious to the organism" seems to contradict the aforementioned argument. Hence my initial incredulity. But if we can agree that a random mutation might confer a benefit for the mutated organism, then we can agree that the variation on which natural selection acts is, at least in part, the result of random mutation.

      quote scottie:

      All I have argued is that this resistance is already there in nature. The question is not how did the resistance in humans come about. We know that, well sort of! The question is how did these genes come about in the first place.

      Then there are three steps to antibiotic resistance. First, the bacteria evolves a gene that confers resistance to some dangerous substance. This substance is "natural" in the sense that it is not man-made (not an artificial antibiotic).

      Second, the bacteria encounters the man-made antibiotic. The gene that conferred resistance to the "natural" substance isn’t much use against the man-made antibiotic until a random mutation tweaks it in such a way that it confers resistance to that man-made antibiotic.

      Third, the bacteria becomes successful because it is immune to the man-made antibiotic. So it freely proliferates and passes its resistance to the man-made antibiotic on to all its friends, and even to other types through horizontal gene transfer.

      So. If I understand you correctly, putting forth antibiotic resistance as an example of beneficial mutation is flawed for this reason: the gene that is altered by the mutation was already conferring resistance to dangerous substances, therefore the mutation didn’t really confer any benefit; it tweaked a benefit that was already there.

      What I don’t understand is why you tried to explain this by citing a paper on horizontal gene transfer. That’s the third step. Why did you go there, if the real question is where the gene in step one came from?

      Maybe you meant that there is no step two? That there are bacteria which are naturally immune to man-made antibiotics because they are immune to natural antibiotics? And that these bacteria spread their immunity through horizontal gene transfer? Which brings us back to the experimentally verified fact that mutation can also cause immunity. In which case HGT is irrelevant.

      I’m sorry, but no matter how I try to unpack your argument, it still strikes me as fundamentally illogical. And the only response you can come up with is to cry "straw man" and quote the same flawed argument that I just excoriated. You say that the sources I linked are "not inconsistent with your statements" but you don’t explain how. You offer no refutation of the copious examples of antibiotic resistance that have nothing to do with HGT.

      Here’s another thing I find curious: you say the resistance was already there in nature because this paper says the resistance genes "evolved in non-clinical (natural) environment before the use of antibiotics by humans." But later on in the paper, they mention that although there are some bacteria which produce natural antibiotics and thus already have genes specifically for antibiotic resistance, "some resistance genes may have other functional roles in their original organisms besides antibiotic resistance." In other words, genes that now confer antibiotic resistance may have served a completely different function in the past. "These examples illustrate the concept that a determinant which contributes to the resistance of human pathogens to antibiotics can be involved in central metabolic processes of environmental bacteria in their natural habitats."

      So, one of the major points of the paper you quoted is that a gene that was originally used to make a protein involved in metabolism might later play a role in antibiotic resistance. This seems to directly contradict your assertion that all antibiotic resistance is "already there in nature." In fact, it supports the idea that natural selection plays a strong role in the evolution of these genes. Because, as any biologist will tell you, natural selection doesn’t work de novo. It takes what is already there and tweaks it. Complex structures don’t evolve overnight. You don’t need the whole mousetrap at once because the individual pieces may be individually useful for other things.

      If the sources I cited were truly consistent with your argument, you should have pulled quotes from them and explained how they supported you. Instead, you cited a new source. Not only does this new source not support your argument, but the parts that you didn’t quote actually directly contradict you.

      quote scottie:

      Ok so you are not interested in discussing the origin of genes with me but you do know the simple answer. Genes are legos made of legos. My my, however did I miss that one. Errr yep I’ve got it. I have been accused of lacking imagination, that’s what it must be. Got to keep working at it.!!

      No, seriously. Google "gene origins." It’s really interesting.

    • #112472
      scottie
      Participant

      Luxorien
      you wrote

      quote :

      But if we can agree that a random mutation might confer a benefit for the mutated organism, then we can agree that the variation on which natural selection acts is, at least in part, the result of random mutation.

      Please don’t take my statement any further than what I have said.
      I said

      quote :

      “Yes I believe that may also happen.”

      To me the jury is still out.
      How does one distinguish between what is a random and what is a prescribed cellular response to outside pressure.

      It is for this reason that I argue that random mutations “mistakes” are mostly deleterious simply because of the cell’s checkpoint and correction processes. These processes ensure integrity to some already existing template. I am not aware of any biologist that disagrees that most random mutations are deleterious.

      Now you go on with your steps to acquired resistance. Allow me for a moment just to
      engage with your first step description.(I will deal with the rest as this develops.)

      quote :

      First, the bacteria evolves a gene that confers resistance to some dangerous substance. This substance is “natural” in the sense that it is not man-made (not an artificial antibiotic).

      Could you explain please; How does the bacteria “evolve” a gene?
      If that is how a gene arrived then could you demonstrate the process.
      That is what the scientific method requires.
      If you are unable to, then you are treating a hypothesis as a fact.
      Now if you recognise you are dealing with a hypothesis that’s ok with me, so long as you don’t quickly slide from hypothesis to fact, as you appear to be doing.
      If I am wrong then please correct me.
      btw I will Google "gene origins"

    • #112475
      LeoPol
      Participant

      Life: the active situational model on the cell membrane, equipped with a polypeptide-nucleic technology
      Polypeptide-nucleic technology: Technological database recorded triplet code of four letters in the DNA-nucleotide carrier, through the device of RNA-IO is implemented in the polypeptide interface.
      It is an ancient, several billion years ago the development of brilliant engineering. Engineers – "active models the situation in lipid membranes". Thus, the question of the origin of life, it is a question of the origin of those ancient membrane-engineers!
      https://www.facebook.com/photo.php?fbid … =1&theater 🙂

    • #112562
      Luxorien
      Participant
      quote scottie:

      Please don’t take my statement any further than what I have said.

      All I’m arguing is proof of concept. If you admit the possibility, that is enough for me.

      quote scottie:

      How does one distinguish between what is a random and what is a prescribed cellular response to outside pressure.

      What pressure is a colony of bacteria being subjected to when you keep them in their optimal environment? How do you account for steady rates of mutation in populations of organisms kept under controlled laboratory conditions?

      quote scottie:

      I am not aware of any biologist that disagrees that most random mutations are deleterious.

      Scroll up. We already talked about this.

      quote scottie:

      Could you explain please; How does the bacteria “evolve” a gene?

      No. It’s not germane to this discussion. See "gene origins" above.

      We can both agree that a bacterial strain which was previously not antibiotic resistant had genes. Where those genes came from is not important at the moment. You focus on this and completely ignore the larger issue of the irrelevancy of horizontal gene transfer.

    • #114085
      Cat
      Participant
      quote Luxorien:

      quote scottie:

      Please don’t take my statement any further than what I have said.

      What pressure is a colony of bacteria being subjected to when you keep them in their optimal environment? How do you account for steady rates of mutation in populations of organisms kept under controlled laboratory conditions?

      Absence of selective pressure leads to increase of diversity = more mutants.

      quote Luxorien:

      quote scottie:

      I am not aware of any biologist that disagrees that most random mutations are deleterious.

      FYI – I am one biologist that disagrees… Most mutations are neutral.

    • #114169
      arfeltayona
      Participant

      Here is a short post…

      How then is mutation (a change in the DNA sequence hence the genome) not a cause for Species Genesis… when basically the main difference between species is genetics?

      How then can accumulation of Mutation not a cause for Species Genesis when differences in environmental pressure could cause a shift in Species Population for varying genome composition…

      Frankly, I’m lost here…

    • #114409
      Sumanth001
      Participant

      Hey guys I am a newbie here. But I have the cracking latest stuff for all of you.
      All of you, beyond doubt believe Miller and Urey’s experiment on origin of life.
      This is one fresh discovery. A group of viruses (mimivirus) have given rise to the three different domains of life i.e., archaea, prokarya(bacteria) and eukarya.

    • #114415
      wildfunguy
      Participant
      quote scottie:

      How does one distinguish between what is a random and what is a prescribed cellular response to outside pressure.

      Didn’t Luxorien say that mutagens facilitate the appearance of resistance? If that could be shown for various cases with various mutagens, I would take it to be strong evidence.

      quote Cat:

      FYI – I am one biologist that disagrees… Most mutations are neutral.

      It depends on whether you’re talking about mutations to the genotype or mutations to the phenotype.

      quote arfeltayona:

      Here is a short post…

      How then is mutation (a change in the DNA sequence hence the genome) not a cause for Species Genesis… when basically the main difference between species is genetics?

      How then can accumulation of Mutation not a cause for Species Genesis when differences in environmental pressure could cause a shift in Species Population for varying genome composition…

      Frankly, I’m lost here…

      Speciation is related to hybridization. According to the biological species concept, separate species cannot produce viable hybrids. Why does this definition work? I’ll give the best explanation with my current understanding.
      An hybrid is kind of like a junk-yard car with incompatible parts. If you’re combining Toyota parts, you might get something that works. If you’re combining Toyota and Nissan parts, you’re less likely to get a working car.
      Anti-evolutionists think that successive mutations can’t result in new adaptations. In other words, the populations can’t evolve new parts. I have never heard the following concepts from an anti-evolutionist, but I’m presuming this to be what follows. When a population is separated geographically, the separated populations shouldn’t evolve their own unique sets of parts (assuming the anti-evo viewpoint). That is, even though they may diverge genetically, the blue-print for optimal functioning shouldn’t change. Thus genetic divergence shouldn’t result in reduced hybrid viability, and the populations should always have the potential to merge back together.
      Again, this is just what is IMO what we should expect to see if the anti-evolutionists are right. We could easily test this by separating an insect population for some time, then observing hybrid viability.

    • #114416
      wildfunguy
      Participant
      quote Sumanth001:

      Hey guys I am a newbie here. But I have the cracking latest stuff for all of you.
      All of you, beyond doubt believe Miller and Urey’s experiment on origin of life.
      This is one fresh discovery. A group of viruses (mimivirus) have given rise to the three different domains of life i.e., archaea, prokarya(bacteria) and eukarya.

      I’m sorry for moving your post to the second-to-last page, especially since it is more on the topic.

    • #114418
      wildfunguy
      Participant

      Considering my metaphor further, I suppose the "∅ beneficial" viewpoint would still be compatible with the idea that the original population contained Toyota parts, Nissan parts, and an intermediate group of Niss-yota parts that were lost during speciation.
      In that case, the initial population should show a wide range of hybrid viability, and the separated populations should not produce hyrbids that consistently fall below that range of viability. Of course, hybrid viability would have to be measured with respect to non-hybrid viability to control for any increase/decrease in harmful mutations.

    • #114581
      Cat
      Participant
      quote wildfunguy:

      quote Cat:

      FYI – I am one biologist that disagrees… Most mutations are neutral.

      It depends on whether you’re talking about mutations to the genotype or mutations to the phenotype.

      Genotype. Change in phenotype is the result of the mutation. There can be no "mutations to the phenotype" by definition…

    • #114734
      Luxorien
      Participant
      quote Cat:

      quote wildfunguy:

      quote Cat:

      FYI – I am one biologist that disagrees… Most mutations are neutral.

      It depends on whether you’re talking about mutations to the genotype or mutations to the phenotype.

      Genotype. Change in phenotype is the result of the mutation. There can be no “mutations to the phenotype” by definition…

      If you have hours of time to waste going back through this ridiculously long thread, I started out saying most mutations were neutral. Then he brought up studies on bacteria that talked about most mutations being harmful. Toward the end, I was attempting to argue that most random errors do cause problems, but cellular mechanisms correct those errors (or cause the resulting piece of DNA to be so broken that it isn’t viable) so that by the time you are looking at phenotypes, most mutations are neutral because many of the most harmful ones have been weeded out.

    • #114807
      Sumanth001
      Participant

      crazy idea but, if u remember the miller and Urey experiment for origin of life, inorganic substances form the proteins. Does this mean that inorganic substances changed in form as time advanced in the young Earth???

    • #115024
      Dthink1010
      Participant

      where’s Scottie on this?

    • #115176
      paradigm
      Participant

      The answer to the question of the meaning of life and the Universe and everything is 67: the number of unique phylogenetic types that exist in the Universe. See “An Introduction to the future of Science with the Paradigm of Types”, which is located at http://home.spin.net.au/paradigm/ts.pdf

      Paradigm

    • #115340
      wildfunguy
      Participant
      quote Sumanth001:

      crazy idea but, if u remember the miller and Urey experiment for origin of life, inorganic substances form the proteins. Does this mean that inorganic substances changed in form as time advanced in the young Earth???

      Later revelations showed that the Miller-Urey experiment didn’t simulate early Earth correctly.

    • #115465
      BasicBiology
      Participant

      In the recent series "Cosmos" with Neil deGrasse Tyson, he seems to think that the most likely origin of life is from comets. Interesting when you consider that not long ago the general consensus was that it was unlikely that any life existed other than that on Earth..

    • #115540
      JackBean
      Participant

      since when there is a consensus about the origin of life?

      And by saying that the life comes from comets, you’re just pushing the problem further away and further in time, but the question still remains. But it is true, that each comet/asteroid could have brought other compounds and when they mixed here, some pre-life could emerge.

    • #115554
      BasicBiology
      Participant

      That’s true, it isn’t really answering the question of what is the origin of life and is really only considering what might be the origin of life on Earth.

      I wasn’t trying to say there is a consensus on the origin of life, but rather just saying that that is what was said in that documentary series by Neil deGrasse Tyson. He is an astronomist so his views may be slightly biased towards astronomical explanations. There are microorganisms though that can survive in some pretty extreme environments for long times.

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