Biology Forum › Community › General Discussion › Virus question…
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- January 22, 2009 at 4:50 pm #10788
biodawgz
ParticipantThe question is true or false: All virus particles produced from infected cells are infectious.
I find this to be very confusing. On the one hand, some virions are non-infective if they become damaged or are missing part of the genome in the cell. I know that a virus particle is non-infective if it cannot replicate, but am not sure if ‘produced’ means replicated.
Is the question saying this: A cell is injected with a virus. Are all virus particles that replicate infectious?
or is it saying. A cell is injected with a virus. Are all the virus particles from this injection in the cell infectious.
- January 22, 2009 at 6:29 pm #88623
jonmoulton
ParticipantI’d read that question as asking whether all of the viral particles released from an infected cell are also infectious.
- January 22, 2009 at 9:39 pm #88627
biodawgz
Participantand would you agree with me, that No they are not.
- January 23, 2009 at 1:08 am #88631
jonmoulton
Participant"some virions are non-infective if they become damaged or are missing part of the genome in the cell"
- January 26, 2009 at 9:03 am #88689
biohazard
ParticipantI think many viruses, especially those with high mutation rates such as retroviruses, produce vast numbers of viral particles that are not infectious. Many mutations easily render some crucial receptor-binding protein or viral enzyme inactive, and thus the virus cannot infect its target cells.
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