Virus question…

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    • #10788
      biodawgz
      Participant

      The question is true or false: All virus particles produced from infected cells are infectious.

      I find this to be very confusing. On the one hand, some virions are non-infective if they become damaged or are missing part of the genome in the cell. I know that a virus particle is non-infective if it cannot replicate, but am not sure if ‘produced’ means replicated.

      Is the question saying this: A cell is injected with a virus. Are all virus particles that replicate infectious?

      or is it saying. A cell is injected with a virus. Are all the virus particles from this injection in the cell infectious.

    • #88623
      jonmoulton
      Participant

      I’d read that question as asking whether all of the viral particles released from an infected cell are also infectious.

    • #88627
      biodawgz
      Participant

      and would you agree with me, that No they are not.

    • #88631
      jonmoulton
      Participant

      "some virions are non-infective if they become damaged or are missing part of the genome in the cell"

    • #88689
      biohazard
      Participant

      I think many viruses, especially those with high mutation rates such as retroviruses, produce vast numbers of viral particles that are not infectious. Many mutations easily render some crucial receptor-binding protein or viral enzyme inactive, and thus the virus cannot infect its target cells.

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